Pharmaceutical r&d granulation system

Optimize your pharmaceutical research with a versatile small-scale granulation system that seamlessly handles blending, drying, and pelletizing, ensuring precise and homogenous outcomes for innovative inhalable and solid dosage formulations.

Processes Pharmaceutical Powders and Inhalable Ingredients

The PharmaConnect® R&D Processing System by GEA is a versatile platform designed for pharmaceutical manufacturers and R&D laboratories, featuring a modular design that allows multiple processes from granulation to blending to be docked to a single control unit. This system excels in creating uniform micronized active ingredients and lactose carrier blends for inhalants, crucial for producing dry powder inhaler products and oral solid dosage tablets. With batch capacities ranging from 200 g to over 25 kg, it supports pilot, laboratory, and bench-top operations, making it ideal for high-speed and mobile production environments. The PharmaConnect® offers seamless integration with existing systems through its proprietary Module Recognition System, ensuring accurate configuration and operation. Constructed with GMP-compliant materials, it meets stringent pharmaceutical standards, while its plug-and-play operation simplifies use. The system is also PAT-compatible and designed for efficient cleaning, which reduces downtime and contamination risks. Furthermore, GEA offers extensive customization and engineering support to suit specific production needs, enhancing flexibility across various pharmaceutical applications.

Benefits

  • Enhances production flexibility with interchangeable process modules for diverse applications.
  • Ensures product consistency and quality with precise control and PAT compatibility.
  • Reduces contamination risk through efficient cleaning and containment design.
  • Supports scalable production from laboratory to pilot scale without compromising data integrity.
  • Decreases downtime with quick module swapping and easy-to-use interface.

General


Applications
Active pharmaceutical ingredients,Pharmaceutical tablets,Oral solid dosage forms,Dry powders,Inhalable products,Excipients,Pharmaceutical powders
End products
Oral solid dosage tablets,High-shear blended apis,Excipient base mixes for tablets,Micronized active ingredients for inhalers,Lactose carrier blends for inhalants,Granulated pharmaceutical tablets,Dry powder inhaler (dpi) products
Steps before
Dispensing raw materials,Purification,Drying,Grinding
Steps after
Tablet Pressing,Coating,Packing,Sterilization
Input ingredients
raw materials,pharmaceutical powders,active pharmaceutical ingredients,base excipients,lactose carrier,aqueous or solvent formulations
Output ingredients
finished tablet,homogenous and stable blends,pellets,formulated products,granules
Market info
GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.

Technical Specifications


Batch size
200 g to 25 kg+
Automation
PLC-controlled
High Shear Granulation
Bottom-driven/Top-driven
Impeller Speed
up to 20 m/s
Working capacity
150 g to 30 kg
Batch vs. continuous
Batch
Energy input
High energy input
Drying,Milling
Included
Pelletization
Available
Blending system
BUCK® IBC
Module Recognition System (MRS)
Yes
Control Interface
Touchscreen
Processing Temperatures
cGMP-compliant

Operating Characteristics


Batch vs. continuous operation
Batch
Automation level
PLC
Cleaning method
CIP / SIP
CIP/SIP
CIP 121°C / SIP 135°C
Energy efficiency
0.5–2 kWh/kg moisture

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm


GMP Compliance
cGMP-compliant
PAT Compatibility
PAT-compatible

Physical Characteristics


Machine Footprint
Compact
Batch size
200 g to 25 kg
Control panel type
Touchscreen interface
Interchangeable bowls
Geometrically scalable
Plug-and-play operation
Yes

Custom Options


Control panel type
Touchscreen
Integration possibilities
Through-the-Wall or Mobile Module
Modularity
Interchangeable process modules
Module detection system
GEA’s Module Recognition System (MRS)
Scalability
Geometrically scaled bowls