Vertical conical dryer for pharmaceutical ingredients

Optimize drying and mixing processes for high-value substances with this Vertical Conical Dryer, which ensures efficient moisture removal and uniform product consistency, essential for quality control in pharmaceutical formulations.

Dries and Mixes Active Ingredients Efficiently

The Vertical Conical Dryer (VCD) from GMM Pfaudler is an energy-efficient vacuum drying solution designed for the precise moisture removal of Active Pharmaceutical Ingredients (APIs) and specialty chemicals. Featuring static and dynamic heat transfer areas, the VCD ensures efficient drying with its vertical installation and bottom discharge design, minimizing heel volumes for optimal emptying. It caters to industries such as pharmaceutical, chemical, fine chemical, and agrochemical, handling end products like antibiotic powders, ibuprofen, and pesticides. With a wide range of filling capacities and a good turndown ratio, the dryer accommodates batch and continuous operations while maintaining high compliance with cGMP and FDA guidelines.

The VCD incorporates a hollow heated agitator with a heatable single or double helical ribbon, providing gentle mixing and efficient heat transfer. Available in stainless steel, Hastelloy, and special alloy options, the dryer offers robust corrosion resistance. Automation options include temperature control units and vacuum recovery systems to enhance process efficiency. The system is designed for easy integration, equipped with optional accessories such as a lump breaker and a dust filter, ensuring smooth operation and maintenance. Maintenance is straightforward with accessible components, and segregation of the drive unit from process areas allows for sterile clean-room installations.

Benefits

  • Enhances product quality with precise moisture control compliant with GMP and FDA standards.
  • Minimizes operational costs through energy-efficient vacuum drying technology.
  • Ensures quick and complete discharge, reducing product waste and process times.
  • Provides flexibility for diverse batch sizes with a wide turndown ratio.
  • Maintains high corrosion resistance with material options suited for harsh chemical processes.

General


Applications
Chemical,Active pharmaceutical ingredients,Fine chemicals,Agro chemicals
End products
Paracetamol,Aspirin,Fertilizer granules,Insecticides,Pesticides,Herbicides,Ibuprofen,Specialty chemical additives,Antibiotic powders
Steps before
Purification,Filtration,Solid-liquid separation
Steps after
Packing,Sterilization,Coating
Input ingredients
Active Pharmaceutical Ingredients,Chemical raw materials,Fine Chemical materials,Agro Chemical materials
Output ingredients
dried product,dried APIs
Market info
GMM Pfaudler is known for manufacturing glass-lined equipment, reactors, and engineered-to-order (ETO) solutions for the chemical, pharmaceutical, and allied industries, recognized for their innovation, quality, and global presence.

Technical Specifications


Heat transfer utilization
Static and dynamic
Installation type
Vertical
Discharge method
Bottom discharge
Filling capacities
Wide range
Operating cost
Lower compared to other dryers
Maintenance cost
Lower compared to other dryers
Automation
Available with automation systems
Shaft sealing designs
Double wet / dry mechanical seal
Agitator type
Hollow heated with helical ribbon
Discharge valve type
Twist close / segmented ball valve
Material of construction
Stainless steel / Hastelloy / special alloys
Drying method
Vacuum drying
Heel volume
Lower heel volumes
Turndown ratio
Good
Optional accessories
Lump breaker,sampling system,condenser,receiver,vacuum pump
Temperature Control Units
Available
Vacuum and solvent recovery
Units available
Dust filter
Options available

Operating Characteristics


Energy efficiency
Lower operating cost compared to other dryers
Batch vs. continuous operation
Batch
Drying mechanism
Effective utilization of static and dynamic heat transfer
Automation level
Available with automation systems
Operating environment
Sterile/clean room areas
Effective discharge
Bottom discharge ensures better emptying

Material Compatibility


Corrosive resistance (e.g. acids)
Stainless steel,Hastelloy,Special alloys
Cleanability
Designed for clean room installation
Biological compatibility
Compliance with cGMP and FDA guidelines


GMP Compliance
Yes
FDA Compliance
Yes
CGMP Compliance
Yes

Physical Characteristics


Compact footprint
Lower footprint
Discharge method
Bottom discharge with twist close valve/segmented ball valve
Machine shape
Vertical Conical

Custom Options


Automation systems
PLC integration
Temperature Control Units
TCU integration
Vacuum and solvent recovery units
Integrated
Shaft sealing designs
Double wet mechanical seals / Dry mechanical seal
Agitator design
Hollow heated agitator with heatable single or double helical ribbon
Bottom discharge
Twist close valve / Segmented ball valve