Sterilizable filter dryer for pharmaceutical applications

Ensure full sterility and efficient moisture removal in critical pharmaceutical processes with this advanced filter dryer, optimizing purity and compliance from filtration to discharge.

Processes and Sterilizes Slurry into Dry Cake

The COMBER Pressofiltro® Series PF 50 – PF 6000 is a versatile sterilizable agitated Nutsche filter dryer from HEINKEL’s esteemed product line, designed to maintain sterility throughout the filtration, washing, drying, and discharge processes. This equipment excels in applications requiring stringent sterility and cleanliness, such as manufacturing active pharmaceutical ingredients, specialty chemicals, and powdered food additives.

With a filtration area ranging from 0.13 to 6 m², and a slurry volume capacity of 55 to 6,000 liters, the COMBER Pressofiltro® is engineered for both batch and pilot operations. Its PLC-controlled system ensures seamless integration and automation, while compliance with cGMP and FDA guidelines guarantees product safety and quality.

Utilizing a steam sterilizable design, it ensures thorough sterilization, reaching all contact points without air entrapment, and incorporates CIP and SIP systems for automatic, efficient cleaning and disinfecting. Fabricated with materials like stainless steel, Hastelloy, and titanium, it offers excellent corrosion resistance. Moreover, it features an aseptic design with externally interchangeable dry running double mechanical seals.

The versatile COMBER Pressofiltro® comes equipped with options for dust filters, sampling valves, and vacuum systems, supporting tailored engineering to meet specific production needs.

Benefits

  • Ensures sterile production with integrated CIP and SIP systems, minimizing contamination risks.
  • Supports high-purity output by maintaining compliance with cGMP and FDA standards.
  • Enhances chemical compatibility with durable material options like stainless steel and Hastelloy.
  • Reduces maintenance time through steam sterilizable design and externally interchangeable seals.
  • Offers customizable configurations to meet diverse operational and production needs.

General


Applications
Chemicals,Surface coating,Fine chemicals,Metal recycling,Food products,Pharmaceuticals
End products
High-purity chemical precursors,Powdered food additives,Flavor enhancers,Active pharmaceutical ingredients,Specialty chemicals,Surface coating powders,Nutraceutical supplements,Recycled metal powders
Steps before
Slurry feeding,Inerting
Steps after
Discharge,Sterilization,Packing
Input ingredients
slurry,liquid mixtures
Output ingredients
dry product,filtered material
Market info
Heinkel (Comber) is renowned for manufacturing industrial engineered-to-order equipment, specializing in filtration, centrifugal, and mixing solutions. They are recognized for their precision engineering, quality, and ability to tailor solutions for pharmaceutical and chemical industries.

Technical Specifications


Filter area
0.13 to 6 m²
Slurry volume
55 – 6,000 liters
Design temperature
-10 to 150°C (14 to 302°F)
Design pressure
-1 to +4 barg (FV to 60 psig)
Heated areas
All product wetted components,including agitator
Automation
PLC-controlled
Cycle temperature
121–135°C
CIP/SIP
CIP 121°C / SIP 135°C
Material wetted components
Stainless steels,Nickel based alloys such as Hastelloy C 22 or Alloy 59,Titanium
Sealing materials
PTFE gaskets,O-Rings in FFKM or FEP encapsulated

Operating Characteristics


Automation level
PLC-controlled
Batch vs. continuous operation
Batch
CIP/SIP
CIP with Cleaning-In-Place,SIP with Sterilization-In-Place
Cleaning method
Automatic CIP/SIP
Energy efficiency
0.5–2 kWh/kg

Material Compatibility


Product wetted materials
Stainless steels,Nickel based alloys such as Hastelloy C 22 or Alloy 59,Titanium
Sealing materials
PTFE gaskets,O-Rings in FFKM or FEP encapsulated

Product type Characteristics


Filling purpose
Nutsche Filtration

Physical Characteristics


Machine footprint
Depends on model (e.g.,PF 50 - PF 6000)
Filter area
0.13 to 6 m²
Slurry volume
55 – 6,000 liters
Discharge method
Automatic / Manual
Tank shape
Nutsche type
Heating areas
All product wetted components,including agitator
Design temperature
-10 to 150°C (14 to 302°F)
Design pressure
-1 to +4 barg (FV to 60 psig)

Custom Options


Control panel type
PLC,HMI with touch screen
Integration possibilities
Interface for DCS