Granulation line for pharmaceutical manufacturing
Enhance your batch production with integrated mixer and fluid-bed technology, offering efficient granulation and drying processes for diverse applications.

Mixes, Granulates, and Dries Pharmaceutical and Food Products
The CCS Granulation Line from DIOSNA is designed to optimize your pharmaceutical and food processing needs. This system seamlessly integrates mixer-granulation and fluid bed processing, allowing for efficient wet granulation followed by precise drying. Capable of producing pharmaceutical tablets, cosmetic cream bases, and nutrient-rich granules, it facilitates everything from yeast-based pre-doughs to specialty chemical granules.
Utilizing a through-the-wall installation, it ensures a strict separation of production and technical areas, promoting operational hygiene and workspace efficiency. With automation in mind, the system is equipped with PC control that complies with 21 CFR Part 11, paired with remote maintenance capabilities to support uninterrupted production.
The CCS Granulation Line is designed to meet stringent safety standards and withstand pressure shocks of up to 12 bar, adhering to ATEX regulations. Its energy-efficient design reduces operational costs while maintaining high throughput, suitable for both pilot and full-scale production. With flexible container sizes and an intuitive interface, it accommodates varied batch sizes effortlessly, ensuring your production line meets evolving demands.
Furthermore, the system supports recipe creation and comprehensive data acquisition, documented with compliant software, enhancing your quality control processes. Available with customizable options, it can be tailored to fit specific application needs, including special solutions for containment in pharmaceutical settings, ensuring your operations are both efficient and compliant with industry standards.
Benefits
- Streamlines production with seamless integration of granulation and drying processes.
- Ensures operational safety and compliance with ATEX standards.
- Enhances efficiency by reducing energy consumption through optimized process controls.
- Provides flexibility with adaptable container sizing for various batch requirements.
- Facilitates comprehensive quality control with 21 CFR Part 11-compliant data documentation.
- Applications
- Food,Feed,Dough,Fine chemicals,Pharma solids,Pre-dough,Cosmetics
- End products
- Bread dough mixes,Pharmaceutical tablets,Nutritional granules,Cosmetic cream bases,Specialty chemical granules,Animal feed pellets,Yeast-based pre-dough
- Steps before
- Material Container Preparation,Recipe Creation,Mixing
- Steps after
- Drying,Batch Data Documentation,Quality Control,Spray Granulation
- Input ingredients
- raw materials,clinical samples
- Output ingredients
- granulated products,production batches
- Market info
- Diosna is known for its expertise in manufacturing industrial dough mixing machines and systems, primarily for the bakery and food industries, showcasing a strong reputation for innovation, quality, and reliable engineered-to-order mixing solutions.
- Automation
- PC control,21 CFR Part 11 compliant,with remote maintenance
- Pressure-shock resistance
- Up to 12 bar
- Batch documentation
- 21 CFR Part 11-compliant software
- Batch vs. continuous
- Batch
- Working mechanism
- Mixing,Granulate,Drying - in combination
- Integrated steps
- Mixer-granulator and fluid bed processor
- Batch vs. continuous operation
- Batch
- Automation level
- PC control with remote maintenance
- Changeover time
- Quick change of material containers
- Safety feature
- Pressure-shock resistant up to 12 bar,ATEX compliant
- Cleaning method
- Compliant with GMP standards
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Granulation type
- Wet granulation with drying
- Spray granulation
- Prepared,retrofittable
- Control panel type
- PC control,21CFR Part 11 compliant
- Integration possibilities
- Remote maintenance
- Container change customization
- Quick change of material containers without tools
- System operation flexibility
- Flexible operation by changing container size and two operating terminals
- Installation design
- Through-the-wall concept