Tipping and filling line for bulk Api powder production
In bulk antibiotic production, precise handling of active pharmaceutical ingredients (APIs) is critical to maintain product sterility and efficiency. The process requires isolating the powder, minimizing contamination risks, and ensuring accurate measurements throughout the tipping and filling stages.
Ensures aseptic conditions in bulk Api production
The Tipping & Filling Line for Bulk API Powder by Comecer is designed specifically for the sterile handling of antibiotic powders. This advanced plant features three fully automatic lines and a component preparation isolator to ensure the API powder remains uncontaminated. The system’s stellar valve enables precise filling, achieving an accuracy of ±25g on a 10kg fill. An automatic cleaning-in-place (CIP) and sterilization-in-place (SIP) system guarantees all product contact parts are clean and sterile. Additionally, the system includes an automatic discharge station, washing, and drying within isolators, and an autoclave offloading process using an anthropomorphic robot under a Grade A isolator. This setup not only maintains the highest operational efficiency but also offers a fully automated process that meets stringent aseptic conditions.
Benefits
- Maintains sterility with Grade A isolation
- Achieves precise filling with ±25g accuracy
- Reduces manual handling with robotic automation
- Ensures thorough cleaning with CIP and SIP systems
- Minimizes contamination risks during production