Microcarrier separation system for adherent cell culture
Enhance cell culture production efficiency by integrating a seamless microcarrier separation process, optimizing yield while minimizing manual handling and operational complexities.
Separates Microcarriers for Adherent Cell Cultures
The Harvestainer™ Microcarrier Separation System from Thermo Scientific is a cutting-edge solution for efficient separation of microcarrier beads in adherent cell culture processes. This closed, single-use system enhances product yield and reduces water and cleaning requirements. Designed for biotech and pharmaceutical applications, it supports the production of monoclonal antibodies, viral vectors, and engineered T cells. Available in capacities of 3 L, 12 L, 25 L, and 50 L, the system integrates seamlessly into existing production lines, offering scalability and high recovery rates. Its design minimizes manual intervention with a dip tube and dipwell for optimal drainage, while operating at room temperature. Constructed from durable PETG material, this system meets sterility standards and requires no additional maintenance, reducing cycle times and process validations. Suitable for various operations, it supports compliance with stringent industry regulations, providing reliability and precision in demanding environments.
Benefits
- Enhances product yield with high recovery rates, minimizing waste in biopharmaceutical and cell therapy production.
- Reduces manual handling and maintenance, lowering operational costs and improving efficiency.
- Scalable design accommodates varying production scales, from small to large volumes.
- Operates as a closed, single-use system, ensuring sterility and regulatory compliance while reducing contamination risks.
- Decreases water usage, aligning with sustainability goals and reducing environmental impact.
- Applications
- Microcarrier-based cell culture,Cell therapy,Adherent cell culture,Biopharmaceuticals,Gene therapy
- End products
- Viral vectors,Engineered t cells,Stem cell-based therapeutics,Monoclonal antibodies,Vaccine components
- Steps before
- Adherent cell culture production,Microcarrier preparation
- Steps after
- Product yield analysis,Process validations,Final product packaging
- Input ingredients
- microcarrier beads,adherent cell culture
- Output ingredients
- separated microcarrier beads,high recovery rates,product yields
- Market info
- Thermo Fisher Scientific is renowned for providing innovative scientific instruments, laboratory equipment, and engineered-to-order solutions across various industries, esteemed for their high-quality products and expertise in life sciences, pharmaceuticals, and biotechnology sectors.
- System Type
- Closed,single-use system
- Capacity
- 3 L,12 L,25 L,50 L
- Automation
- Inline microcarrier separation
- Material
- PETG
- Sterility
- Sterile
- Shipping Condition
- Room Temperature
- Working Mechanism
- Inline microcarrier separation
- Scalability
- Smaller-scale and larger-scale applications
- System Type
- Closed,single-use
- Cleaning Method Reduction
- Reduced CIP/SIP
- Automation Level
- Minimal manual intervention
- Yield Improvement
- Higher product yields
- Maintenance Reduction
- Eliminated equipment maintenance
- Cycle Time Reduction
- Reduced cycle times
- Biological compatibility
- Sterile PETG
- Cleanability
- CIP/SIP compatible
- Corrosive resistance (e.g. acids)
- Yes
- Abrasion resistance
- Moderate
- Application
- Adherent cell culture production
- Discharge method
- Inline microcarrier separation
- Unit size
- 3 L / 12 L / 25 L / 50 L
- System Type
- Closed,single-use system
- Secondary containment device
- Tray / Drum
- System Size Options
- 3 L,12 L,25 L,50 L
- Secondary Containment Device
- Tray (3 L and 12 L),Drum (25 L and 50 L)
- Bioprocess Container Design
- 3D BPC with Dip Tube and Dipwell