Twin-screw extruder for pharmaceutical formulations

Processes Pharmaceutical Formulations in Continuous Mode

The Pharma 16 Twin-Screw Extruder from Thermo Scientific is engineered for pharmaceutical manufacturers seeking efficient pilot-scale and continuous R&D processes. This dual-function extruder effortlessly switches between hot melt extrusion (HME) and wet granulation (TSG) to optimize drug process development. It facilitates the production of extended-release tablets, film-coated pills, and granulated APIs, minimizing the use of costly materials and time typically required in batch processes. With a throughput of up to 5 kg/h for HME and 15 kg/h for TSG, it meets the demands of solid dosage forms. The system integrates seamlessly into existing production lines with plug-and-play compatibility, ensuring quick setup and scalability to larger extruders. Constructed to meet GMP and FDA standards, the Pharma 16 supports various operational conditions and offers reliable performance with minimal energy wastage. Enhanced with seven barrel zones, including a permanently cooled first zone and die heater, it ensures precise temperature control. Benefiting from its compact design, the extruder simplifies cleaning and maintenance, making it ideal for dynamic pharmaceutical environments.