Compact flash and prep Hplc chromatography system
Streamline your purification processes with a versatile system that integrates flash and preparative HPLC, providing precise separation and improved purity for complex compounds while saving valuable lab space.

Purifies and Separates Compounds Efficiently
The Pure Chromatography Systems from BUCHI offer compact and automated solutions for efficient purification and separation in pharmaceutical, biotechnology, chemical, and food industries. Designed for flexibility, these systems combine flash and preparative HPLC capabilities within a single unit, allowing precise compound isolation. Ideal for applications ranging from biopharmaceuticals to natural products, these systems ensure minimal laboratory space usage with high safety standards, featuring a closed fraction collector bay for clean air. The integrated UV and ELSD detection, combined with RFID technology, enhances accuracy and mitigates risk. With user-friendly interfaces minimizing training time, these systems optimize lab operations with remote control and robust leak and pressure sensors. Capable of both liquid and solid sample injection, they support a range of applications. The Pure systems meet stringent laboratory requirements, offering scalable solutions with easy maintenance.
Benefits
- Optimizes lab space with compact design and integrated solvent platform.
- Enhances operational safety with closed fraction collector and automated monitoring sensors.
- Minimizes training time with an intuitive user interface and simple controls.
- Ensures precise purification with combined flash and prep HPLC modes and integrated UV/ELSD detection.
- Offers flexible sample processing with universal injection modes for diverse applications.
- Applications
- Vitamins,Natural products,Active pharmaceutical ingredients,Fine chemicals,Nutraceuticals,Pharmaceutical powder,Biopharmaceuticals,Enzymes,Dietary supplements
- End products
- Steps before
- Synthesis,Extraction,Fermentation,Solution Preparation
- Steps after
- Concentration,Purification,Isolation,Analysis
- Input ingredients
- liquid samples,solid samples,solvents
- Output ingredients
- purified compounds,isolated components,pure substances
- Market info
- Buchi is renowned for its expertise in laboratory and industrial solutions, particularly in producing high-quality equipment for chemical analysis and lab processes, known for precision and reliability in the pharmaceutical, chemical, and food industries.
- Flow rate (flash mode)
- 250 ml/min
- Flow rate (prep HPLC mode)
- 0 – 100 ml/min
- Pressure range (flash mode)
- 0 – 50 bar
- Pressure range (prep HPLC mode)
- 0 – 300 bar
- UV scan function
- Yes
- UV - Vis wavelength range
- 200 – 800 nm
- Detection type
- UV and ELSD
- Automation
- Fully automated
- Compact footprint
- Yes
- Remote control capability
- Yes
- Sample injection modes
- Liquid and solid
- Cartridge holder placement
- Front
- Automation level
- Manual / PLC / SCADA
- Batch vs. continuous operation
- Batch / Inline Continuous
- Energy efficiency
- 0.5–2 kWh/kg moisture
- Safe Operation
- Leak and pressure sensors,remote control
- Space Saving
- Compact design,extra solvent platform
- Cleaning method
- CIP / Manual
- Sample Injection Modes
- Liquid and solid injection,bottom-top or top-bottom
- Corrosive resistance (e.g. acids)
- Yes
- Density/particle size
- 0.5–2.5 g/cm³
- Cleanability
- Easy to clean
- Biological compatibility
- Yes
- Compact footprint
- Yes
- System Design
- Compact and fully automated
- Discharge method
- Universal sample injection
- Cartridge/Column Holder Placement
- Front of the system
- Control panel type
- Intuitive software interface
- Compact footprint
- Yes
- System Design
- Compact and fully automated
- Sample injection modes
- Liquid and solid injection
- Pump type
- Flash and prep HPLC mode
- Detection type
- UV and ELSD
- Solvent Platform
- Extra platform on top
- Remote Control
- Yes
- Safety Monitoring
- Automatic sensors for pressure and vapor
- Validation Technology
- RFID on cartridges and racks