Adherent cell expansion platform
Maximize adherent cell culture scalability and minimize operational costs with a platform designed for continuous high-density production and efficient bioprocessing.
Facilitates Continuous Adherent Cell Expansion
The Livit ACE from Getinge is a comprehensive continuous adherent cell culture platform designed to optimize cell-based bioprocess applications. This platform excels in addressing the complexities of scalable cell growth, detachment, and collection processes. Utilizing proprietary technologies such as CellRev’s Continuase™ for controlled cell detachment, Livit ACE supports steady state operations at high cell densities. Ideal for producing personalized cancer vaccines, CAR-T cell therapies, and recombinant proteins, it integrates seamlessly into biotech and pharmaceutical production lines. Featuring automated, high-capacity operations, Livit ACE ensures efficient bioprocessing with reduced capital costs and floor space. Available in single-use and multi-use bioreactor configurations, it emphasizes operational flexibility and supports compliance with industry standards, making it suitable for diverse production environments.
Benefits
- Enhances production efficiency by maintaining high cell densities in continuous operations.
- Minimizes costs and space utilization with compact design and integrated cell processing.
- Ensures process consistency with automated control reducing risk of human error.
- Streamlines scale-up from research to production, ensuring reproducibility and reducing development timelines.
- Facilitates seamless integration into existing biopharmaceutical and cellular agriculture processes.
- Applications
- Cellular agriculture,Biopharmaceuticals,Cell-based vaccines,Cell therapies
- End products
- Car-t cell therapies,Personalized cancer vaccines,Monoclonal antibodies,Lab-grown meat,Stem cell therapies,Recombinant proteins
- Steps before
- Cell seeding,Bioreactor setup,Media preparation
- Steps after
- Cell collection,Downstream processing,Cell banking
- Input ingredients
- adherent cells,Continuase™ reagent,bioreactor culture medium
- Output ingredients
- expanded cells,cell bank,cells for downstream processing
- Market info
- Getinge is known for providing innovative healthcare and life sciences products, specializing in medical technology, infection control, surgical workflows, and critical care solutions. They maintain a strong reputation for quality and technological advancement in these sectors.
- Automation
- High-level automation integrated
- Scalability
- Seamless scale-up capability
- Stability
- Enhanced process stability
- Capacity
- High-density cell culture
- Process Type
- Continuous bioprocessing
- Reagent
- Continuase™ for cell detachment
- Detachment Method
- Proprietary controlled detachment
- Cell Harvesting
- Continuous cell collection
- Automation level
- Integrated automation
- Batch vs. continuous operation
- Continuous operation
- Integration level
- Integrated continuous bioprocessing
- CIP/SIP capability
- Available
- Materials of construction
- Single-use or multi-use options
- Application specificity
- Cell-based vaccines,Cell therapies
- Process stability
- High stability with steady state operation
- Scalability
- High scalability
- Productivity
- Superior productivity compared to batch processing
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Process Intensification
- Yes,improves productivity and reduces costs
- Compact footprint
- Yes
- Machine footprint
- Small/Medium
- Tank shape
- Cylindrical
- Feed method
- Automated seeding
- Discharge method
- Continuous collection
- Control panel type
- Digital/PLC-controlled
- Control panel type
- Getinge Livit Flex (dual) controller with Livit software
- Footprint
- Compact due to improved productivity