Flexstream fluid bed processor for pharmaceutical applications
Addressing the limitations of traditional fluid bed processing, this advanced unit consolidates drying, granulation, and coating processes, ensuring superior product homogeneity and streamlined production with efficient scale-up and containment features.

Combines Granulation, Drying, and Coating Processes
The FlexStream Fluid Bed Processor from GEA revolutionizes pharmaceutical solid dosage manufacturing by seamlessly integrating granulation, drying, and coating into one compact system. Utilizing GEA’s proven fluid bed technology, this processor addresses traditional challenges like scale-up and material handling with linear scalability and fully contained loading and unloading. Designed for producing tablet coatings, APIs, and controlled-release tablets, it operates efficiently in both batch and continuous modes, with high-speed capabilities. Its single product container minimizes footprint while ensuring superior product homogeneity. Featuring PLC-controlled automation, the FlexStream supports in-line particle growth measurement for precise process control, reducing energy consumption through optimized airflow management. Constructed with GMP-compliant materials, it is equipped with WIP and CIP systems, ensuring easy and effective cleaning. This processor integrates seamlessly into pharmaceutical and chemical production lines, offering robust customization options to meet specific scale and process requirements.
Benefits
- Enhances process efficiency with seamless transition between granulating, drying, and coating.
- Reduces scale-up complexity, ensuring consistent product quality across production volumes.
- Optimizes energy usage through advanced airflow management, reducing operational costs.
- Ensures clean, contamination-free operations with integrated CIP and WIP systems.
- Configurable design accommodates custom operational needs, improving versatility in production lines.
- Applications
- Granules,Coating materials,Tablets,Solid dosage forms,Pharmaceuticals
- End products
- Effervescent granules,Active pharmaceutical ingredients (apis),Tablet coatings,Film-coated tablets,Multi-layer tablets,Granulated excipients,Controlled-release tablets
- Steps before
- High Shear Mixing,Granulation,Blending,Liquid Preparation
- Steps after
- Tablet Compression,Packaging,Sterilization
- Input ingredients
- dry powders,aqueous granulations,solvent granulations,raw materials for solid dosage forms,organic solvents
- Output ingredients
- dried granules,coated pellets,tablets,blended powders
- Market info
- GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.
- Capacity
- Single module processing
- Automation
- PLC-controlled
- Cleaning method
- CIP / WIP
- Loading/Unloading
- Fully contained
- Particle growth measurement
- PAT-compatible in-line
- Spraying systems
- Nozzles,pumps,and liquid preparation units
- Airflow management
- Gill Plate airflow
- Installation type
- Through-the-wall
- Solvent emission control
- Open- and closed-cycle systems
- Scale-up
- Linear scale-up
- Working mechanism
- Fluid bed granulation,drying,and coating
- Integrated steps
- Granulation,drying,coating in a single module
- CIP/SIP
- WIP and CIP
- Batch vs. continuous operation
- Batch / Inline Continuous
- Automation level
- Automation with PLC
- Changeover time
- Minimal due to no mechanical adjustment needed
- Cleaning method
- CIP
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Container size and shape
- Customizable
- Compact footprint
- Reduced build envelope
- Discharge method
- Lean phase conveying system
- Control panel type
- PAT-compatible in-line measurement
- Mechanical adjustment
- Not necessary for switching operations
- Control panel type
- PLC / HMI / SCADA
- Integration possibilities
- PAT-compatible / In-line particle growth measurement
- Installation type
- Through-the-wall installation
- Cleaning system
- WIP / CIP