Microcarrier separation system for adherent cell cultures
Enhance your production efficiency with a scalable, single-use system designed for high recovery rates in adherent cell culture processing, streamlining microcarrier separation while minimizing manual interventions and upkeep.
Separates Microcarrier Beads in Cell Culture
The Harvestainer Microcarrier Separation System from Thermo Scientific is a reliable solution for efficient separation of microcarrier beads in adherent cell culture processes. This closed, single-use system enhances production by increasing yields and minimizing contamination risks through its in-line processing capabilities. Ideal for biopharmaceutical applications, including the production of vaccines and monoclonal antibodies, the system is scalable for both small and large-scale operations. It features a pre-assembled bioprocess container (BPC) with a dip tube designed for optimal drainage, reducing manual decanting and maintenance needs. With capacities ranging from 3L to 50L, it supports compliance with strict bioprocessing standards, offering sterilized PETG material suitable for diverse biopharma and biotech environments. By reducing clean-in-place and steam-in-place requirements, it significantly cuts down water for injection usage, thus aligning with sustainable production practices.
Benefits
- Enhances product yield by providing efficient microcarrier bead separation.
- Reduces contamination risk with a closed, single-use system.
- Decreases operational costs by minimizing clean-in-place requirements.
- Supports scalability from small to large-scale cell culture applications.
- Lowers water usage, contributing to sustainable production practices.
- Applications
- Cell and gene therapy,Biopharmaceuticals,Adherent cell culture production
- End products
- Vaccines,Gene therapy vectors,Monoclonal antibodies,Biologics,Car-t cells,Stem cell therapies
- Steps before
- Cell culture preparation,Microcarrier bead addition,Adherent cell seeding,Cell growth and expansion
- Steps after
- Product collection,Cell harvest,Final product refinement,Quality control and analysis
- Input ingredients
- microcarrier beads,adherent cell cultures
- Output ingredients
- separated microcarrier,recovered cells,higher product yields
- Market info
- Thermo Fisher Scientific is renowned for providing innovative scientific instruments, laboratory equipment, and engineered-to-order solutions across various industries, esteemed for their high-quality products and expertise in life sciences, pharmaceuticals, and biotechnology sectors.
- Capacity
- 3 L,12 L,25 L,50 L
- Material
- PETG
- Sterility
- Sterile
- System Type
- Closed,single-use
- Container Configuration
- 3D Bioprocess Container (BPC)
- Containment Device
- Tray or drum
- Dip Tube Design
- Dipwell design
- Shipping Condition
- Room Temperature
- Application
- Adherent cell culture production
- Usage
- For Research Use Only
- Working mechanism
- Microcarrier bead separation
- Integrated steps
- Inline microcarrier separation
- CIP/SIP
- Reduces CIP and SIP requirements
- Batch vs. continuous operation
- Inline Continuous
- Automation level
- Manual
- Energy efficiency
- Increases product yields
- Cleaning method
- Closed system
- Biological compatibility
- Yes
- Cleanability
- Easy to clean
- Corrosive resistance (e.g. acids)
- High resistance
- Density/particle size
- Suitable for microcarrier beads
- PETG compatibility
- Yes
- Use
- Adherent cell culture production
- Unit Size
- 3 L / 12 L / 25 L / 50 L
- Product Design
- Closed,single-use system
- Containment Device
- Tray or Drum
- Containment Design
- Secondary containment device
- System capacity options
- 3 L / 12 L / 25 L / 50 L
- Unit configuration
- Single-use
- Containment device type
- Tray / Drum
- Dip tube design
- Dipwell
- System scalability
- Smaller-scale to larger-scale