Single-use separator for cell harvesting
Achieve maximum cell harvesting efficiency with single-use technology, streamlining batch processes and significantly reducing downtime by eliminating the need for cleaning and sterilization between cycles. Ideal for scalable production scenarios where speed and cleanliness are critical.
Clarifies and Harvests Cells from Cultures
The GEA kytero® single-use Separator, engineered by GEA, offers a streamlined solution for cell harvesting in the pharmaceutical and biotech sectors. This disk stack separator excels in clarifying mammalian and E. coli cultures without the need for complex cleaning cycles, thanks to its single-use design. This setup not only reduces batch preparation time but also eliminates the dependency on filtration systems by cutting the required filter area significantly. The separator is perfect for producing monoclonal antibodies, vaccine components, and protein therapeutics with high separation efficiency. It integrates seamlessly into any pharma cleanroom environment and fits within plug-and-produce operations. With no need for SIP/CIP processes, it allows rapid batch turnover, enhancing throughput and operational flexibility. Engineered with a contact-free drive system, it ensures low maintenance and high reliability, designed to meet GMP standards and streamline your production line operations.
Benefits
- Accelerates batch preparation by eliminating SIP/CIP steps, increasing production efficiency.
- Decreases reliance on large filtration systems, saving space and reducing waste.
- Enhances operational flexibility with quick changeover capabilities using single-use components.
- Maintains productivity with tool-free disassembly and assembly for minimal downtime.
- Integrates seamlessly into cleanroom environments, supporting GMP compliance.
- Applications
- Liquid formulations,Biopharmaceuticals,Mammalian cells,E. coli,Pharmaceuticals
- End products
- Gene therapy vectors,Mammalian cell cultures,Monoclonal antibodies,Insulin formulations,E. coli expression systems,Protein therapeutics,Recombinant proteins,Vaccine components
- Steps before
- Cell cultivation,Cell culture preparation,Media preparation
- Steps after
- Formulation,Filling,Lyophilization,Sterilization
- Input ingredients
- mammalian cells,E.coli,cell cultures
- Output ingredients
- harvested cells,clarified solution,biomass-free liquid
- Market info
- GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.
- Solids Capture Rate
- Up to 99%
- Preparation Time
- 5 minutes
- Batch Operation
- Yes
- Filter Area Reduction
- Up to 100% primary,50% secondary
- CIP/SIP Requirement
- No
- Plug,Produce Setup
- Yes
- User Handling
- User-friendly,no tools required
- Batch vs. continuous operation
- Batch
- Changeover time
- 5 minutes
- CIP/SIP
- No SIP/CIP
- Cleaning method
- Manual
- Plug,Produce Time
- 5 minutes
- Filter Area Reduction
- 100% Primary / 50% Secondary
- Biological compatibility
- Suitable for mammalian cells and E.coli
- Cleanability
- Single-use,no CIP/SIP required
- Corrosive resistance (e.g. acids)
- Not applicable (Single-use)
- Density/particle size
- Potentially 99% solids capture rate
- Machine footprint
- Compact
- Discharge method
- Single-use bags and hoses
- Control panel type
- User-friendly
- Control panel type
- User-friendly interface
- Integration possibilities
- Plug,produce operation
- Compact footprint
- Fits into any pharma cleanroom
- Single-use components
- Bowl cartridge,bags,hoses
- Easy changeover
- No tools required