Laboratory mixer mill for small volume grinding

Designed for rapid homogenization and size reduction, this versatile mixer mill efficiently processes small volume samples, ensuring consistent results across biological, chemical, and geological applications. Ideal for labs needing precise control over mixing parameters for optimal extraction and analysis outcomes.

Mixes, Homogenizes, and Reduces Sample Size

The Mixer Mill MM 400 by Retsch is an advanced laboratory device engineered for efficient sample preparation and homogenization across multiple industries. Utilizing radial oscillations and high-energy impacts, it effectively mixes, homogenizes, and reduces sample sizes, making it ideal for applications such as DNA/RNA extraction, isotopic sample preparation, and cryogenic grinding. With a frequency range up to 30 Hz, the MM 400 handles a variety of materials, including biological samples, pharmaceuticals, and geological materials. It supports two grinding stations, caters to bench-top operations, and can accommodate capacities of up to 2 x 20 ml. The digital control system and programmable SOPs ensure precise and reproducible results. Designed for the R&D and laboratory departments, it is essential for pharmaceutical laboratories, research institutions, and environmental testing labs. Available in materials like stainless steel and zirconium oxide, it ensures contamination-free preparations, adhering to rigorous industry standards. Its compatibility with various jar materials and optional accessories further enhances its versatility and customization potential.

Benefits

  • Enhances research efficiency with rapid sample preparation and homogenization.
  • Supports versatile applications, accommodating both biological and mechanical samples.
  • Ensures reproducible results with programmable SOPs and precise digital controls.
  • Minimizes contamination risk with a range of material options such as zirconium oxide.
  • Enables diverse processing needs, including cryogenic grinding and cell disruption, suitable for laboratory and pharmaceutical applications.

General


Applications
Chemicals,Construction materials,Minerals,Metals,Waste samples,Agricultural products,Environmental samples,Glass/ceramics,Plant materials,Food products,Geological materials,Textiles,Biological samples,Pharmaceuticals
End products
Hard mineral pulverizations,Protein extracts,Waste biomass homogenizations,Isotopic analysis sample preparations,Recycled material pellets,Geological powder samples,Ceramic powder mixtures,Herbal extract suspensions,Pesticide-treated plant extracts,Homogenized construction material samples,Textile fiber samples,Dna/rna pellets,Cannabis extracts,Soil sample suspensions,Homogenized tissue for research
Steps before
Sample Collection,Pre-cooling,Homogenization,Cell Disruption Preparation
Steps after
Sample Analysis,Isotope Analysis,Pesticide Extraction,Protein Extraction
Input ingredients
alloys,animal feed,bones,ceramics,cereals,chemical products,coal,coke,drugs,electronic scrap,glass,grains,hair,minerals,oil seeds,ores,paper,plant materials,plastics,sewage sludge,soils,straw,tablets,textiles,tissue,tobacco,waste samples,wood,wool,microalgae,capsules with liquid,polyurethane pellets,concrete
Output ingredients
homogenized powders,suspensions,grinded mixtures,cryogenically processed samples,homogenized biological samples,cell disrupted suspensions,DNA/RNA extraction,protein extraction,herbal ingredient extraction,QuEChERS extracted pesticides,pellets for XRF,in-situ RAMAN spectroscopy ready samples,fine powders,mechanochemically altered substances
Market info
RETSCH is known for its high-quality laboratory equipment for sample preparation and particle size analysis, including mills, crushers, and sieve shakers, praised for their precision, durability, and reliability in research and industrial applications.

Technical Specifications


Max Speed
30 Hz
Feed Size
Up to 8 mm
Final Fineness
~ 5 µm
Batch Size / Feed Quantity
Max 2 x 20 ml
Vibrational Frequency
3 - 30 Hz (180 - 1800 min-1)
Mean Grinding Time
30 s - 2 min
Max Grinding Time
99 h
Dry Grinding
Yes
Wet Grinding
Yes
Cryogenic Grinding
Yes
Cell Disruption with Reaction Vials
Yes,up to 20 x 2.0 ml
Grinding Jar Sizes
1.5 ml / 5 ml / 10 ml / 25 ml / 35 ml / 50 ml
Setting of Grinding Time
Digital,10 s - 8 h
Storable SOPs
12
Storable Cycle Programs
6
Power Consumption
165 W
Net Weight
~ 27.5 kg

Operating Characteristics


Automation level
Manual / PLC / SCADA
Batch vs. continuous operation
Batch
Cleaning method
Manual / Pre-cooling in liquid nitrogen
Energy efficiency
Low kWh/kg

Material Compatibility


Biological compatibility
DNA/RNA
Abrasion resistance
Steel,zirconium oxide
Cleanability
Stainless steel jars
Corrosive resistance (e.g. acids)
Zirconium oxide
Density/particle size
glass beads

Product type Characteristics


Cell disruption
DNA/RNA,Protein extraction


CE marking
Yes
ISO/IEC 17025
Applicable
ISO 9000ff
Applicable

Physical Characteristics


Compact footprint
385 x 350 x 470 mm
Net Weight
~ 27.5 kg
Max Feed Size
8 mm
Grinding Jar Sizes
1.5 ml / 5 ml / 10 ml / 25 ml / 35 ml / 50 ml
Grinding Stations
2
Clamping Device
Self-centering
Type of Grinding Jars
Screw top design

Custom Options


Control panel type
Touch display
Jar materials
Hardened steel,stainless steel,agate,tungsten carbide,zirconium oxide,PTFE,PMMA
Grinding modes
Dry,wet,cryogenic
Sample adapters
Adapters for single-use vials,conical centrifuge tubes
Grinding stations
2 grinding stations
Programmable settings
Storable SOPs and cycle programs
Size range for grinding balls
5 mm to 25 mm
Cryogenic processing options
Pre-cooling in liquid nitrogen,CryoKit available
Frequency calibration
Calibrated speed and time
Noise reduction features
Significant noise reduction
Sample throughput enhancement
Multiple adapters for increased sample throughput