Lab-scale fermenters for research and development
Optimize your small-scale production with compact bioreactors designed for precise control in fermentation, mixing, and aeration processes, ensuring quality outcomes from monoclonal antibodies to craft beers.
Conducts Fermentation and Process Control Operations
The RALF Bioreactor from Bioengineering AG is designed for precise monitoring and control of fermentation processes, accommodating industries such as biopharmaceuticals, food, and cosmetics. With processing capacities ranging from 1.3 to 4.5 liters, it supports batch, fed-batch, and perfusion operations using robust glass vessels. The bioreactor is equipped with BioSCADA software for intuitive control, ensuring compliance with 21 CFR Part 11 standards. Its modular construction allows integration with various measuring and control technologies, including pH, pO2, and temperature regulation. Noteworthy for its efficient gassing through up to six lines and reliable mixing options, the RALF Bioreactor maintains energy efficiency with an optimized footprint. Cleaning is streamlined with built-in CIP systems, and customization options facilitate tailored configurations to specific production needs.
Benefits
- Enhances production efficiency with precise, reliable process control.
- Facilitates seamless scale-up and scale-down to meet research and production demands.
- Minimizes contamination risk with integrated CIP systems for easy cleaning.
- Offers flexibility with customizable configurations to suit diverse application needs.
- Complies with strict regulatory standards, ensuring product quality and safety.
- Applications
- Homeopathy,Nutritional products,Beverage,Alternative medicine,Cosmetics,Chemical products,Biopharmaceuticals,Food products,Pharmaceuticals
- End products
- Craft beer,Anti-aging cream,Petrochemical catalysts,Homeopathic tinctures,Active pharmaceutical ingredients (apis),Monoclonal antibodies,Herbal tinctures,Protein supplements,Yogurt cultures
- Steps before
- Media Preparation,Sterilization
- Steps after
- Harvesting,Cleaning
- Input ingredients
- culture media,nutrients,microorganisms,gases
- Output ingredients
- fermented products,biomass,by-products,exhaust gases
- Market info
- Bioengineering is known for its expertise in designing and manufacturing customized bioreactors and fermenters, serving the biotechnology and pharmaceutical industries. They are reputed for high-quality, engineered-to-order solutions and innovative process technologies.
- Processing capacity
- 1.3 / 2.5 / 3.3 / 4.5 liters
- Vessel type
- Single or double-walled glass vessels
- Drive Type
- Direct top drive with axial face seal or magnetic clutch
- Stirrer Types
- Rushton,propeller stirrers,pitched-blade stirrers
- Aeration types
- Tube,ring sparger,sinter sparger,bubble-free gassing
- Temperature control
- Heating pad and cooling fingers,heating circuit via perfused baffles,heating circuit via double wall of vessel
- Measurement and control technology
- Agitation,temperature,pH,pO2,foam/level control,redox,OD,weight,exhaust analysis
- Gas modules
- Up to 6 individual gassing lines with pulsed valves or mass-flow controllers
- Pump modules
- Up to 6 pumps integrated in the control unit and one external pump
- Configuration
- Up to 6 bioreactors controllable with a single control unit
- Process types
- Batch,fed-batch,perfusion processes
- Control software
- BioSCADA,compliant with 21 CFR Part 11
- Automation level
- BioSCADA / SCADA / PLC
- Batch vs. continuous operation
- Batch / Fed-batch / Perfusion
- CIP/SIP
- In-situ sterilizable / Autoclavable
- Cleaning method
- CIP / Manual
- Corrosion resistance
- High
- GMP Compliance
- cGMP standards
- 21 CFR Part 11
- Compliant
- Modular design
- Compact and extendable
- Control system integration
- BioSCADA software
- Control panel type
- Customized HMI options
- Vessel type
- Single or double-walled glass vessels
- Stirrer type
- Rushton,propeller,pitched-blade
- Gas module configuration
- Up to 6 individual gassing lines
- Pump module configuration
- Up to 6 pumps,plus one external
- Temperature control options
- Heating pad,cooling fingers,baffles
- Aeration method
- Tube,ring sparger,sinter sparger
- Configuration options
- Up to 6 bioreactors with a single control unit