Virus filtration systems for biologics manufacturing

Enhance virus filtration efficiency in biologics with scalable, easy-to-use systems designed to handle large volumes and ensure robust viral clearance across complex processing conditions.

Facilitates Scalable and Efficient Virus Filtration

Viresolve®Pro/Pro+ Magnus Holders and the Mobius®FlexReady Solution from MilliporeSigma are engineered to provide reliable viral clearance in biologics manufacturing. Designed to accommodate the complex filtration needs of monoclonal antibodies, mRNA, and protein-based drugs, this system combines modular filter holders with single-use flow paths for flexibility and scalability. The Viresolve®Pro system integrates seamlessly into production lines, offering quick, manual setup and fast hardware installation. Its vertical orientation and minimized footprint adapt to varying processing capacities, allowing for easy scaling from pilot to large-scale operations. Constructed to avoid product contact, the system offers robust performance with efficient energy use. These solutions are compliant with industry standards, ensuring safety in pharma and biopharma processes. Maintenance is streamlined through simple manual hydraulics, and customization is available to meet specific operational needs.

Benefits

  • Enhances viral safety by ensuring efficient scalability from pilot to production scale.
  • Simplifies setup and maintenance with modular design and manual hydraulics.
  • Minimizes contamination risk by avoiding product contact with filter components.
  • Adapts to changing production needs with flexible single-use flow paths.
  • Meets compliance standards for biopharmaceutical manufacturing environments.

General


Applications
Proteins,Biopharmaceuticals,Mabs,Mrna,Pharmaceuticals
End products
Protein-based drugs,Monoclonal antibody therapies,Mrna vaccines,Viral vector vaccines,Biologic drug products
Steps before
Chromatography,Chemical Treatment,Prefiltration
Steps after
Sterilization,Packing,Viral Clearance Assessment
Input ingredients
feed streams,biologics
Output ingredients
viruses,virus-free product
Market info
Merck is known for its focus on life sciences, healthcare, and performance materials, offering products like pharmaceuticals, biopharmaceuticals, and high-tech materials. It has a strong reputation for innovation and quality in these sectors.

Technical Specifications


Loading and Unloading
Quick and easy
Product Contact
No
Holder Footprint
Minimized
Orientation
Vertical
Rod Length
Multiple lengths available
Scalability
6x within same footprint
Hydraulics
Simple manual
Modular Design
Yes
Pod Filters
1 to 30
Adaptability
Maximum with single-use flow paths
Setup Time
Fast

Operating Characteristics


Scalability
6x scalability with modular design
Load/Unload Ease
Quick and easy loading and unloading
Holder Footprint
Minimized with vertical orientation
Orientation
Vertical orientation
Material Contact
No product contact
Hydraulics
Simple manual hydraulics
Adaptability
Maximum adaptability with single-use flow paths
Setup Time
Fast setup of hardware
Configuration Ease
Easy system configuration and reconfiguration

Physical Characteristics


Machine Footprint
Minimized holder footprint with vertical orientation
Loading/Unloading
Quick and easy loading and unloading
Holder Type
Pod filter Holder for Viresolve®Prefilter
Scalability
6x scalability within the same footprint
Configuration
Modular format
Rod Lengths
Multiple lengths for various-sized installations
Construction
Robust construction,easy to use and set up
Material Contact
No product contact
Hydraulics
Simple manual hydraulics
Filter Holder
Viresolve®Pro Magnus Holder

Custom Options


Holder configuration
Single-use / Modular
Scalability
6x within the same footprint
Loading and unloading
Quick and easy
Footprint orientation
Vertical
Hydraulics type
Simple manual