Inert loop for safe organic solvent spray drying
Ensure safe handling and efficient recovery of organic solvents in spray drying processes, minimizing explosion risks and environmental impact while optimizing operational costs.

Safely Recovers and Recycles Organic Solvents
The Inert Loop S-395 from BUCHI is designed to safely handle organic solvents in laboratory-scale spray drying applications. It operates by creating an inert gas atmosphere, preventing explosive conditions through precise oxygen and pressure control. This system is pivotal for industries like pharmaceuticals, chemicals, and food, where safe solvent recovery is essential. The Inert Loop S-395 offers environmental and cost benefits by minimizing inert gas consumption and recycling up to -30 °C through its closed-loop cooling circuit. It seamlessly integrates with BUCHI’s Mini Spray Dryer S-300, utilizing an intuitive PLC system for easy operation and possible combination with the Dehumidifier S-396 for handling solvent and water mixtures. Fabricated with durable materials suitable for corrosive environments, this equipment ensures long-lasting performance and compliance with industry safety standards. Customizable and compact, the S-395 reduces installation space with its integrated trolley, promoting a cleaner, more efficient laboratory workflow.
Benefits
- Enhances lab safety by preventing explosive conditions with precise oxygen and pressure control.
- Reduces operational costs through efficient inert gas consumption and solvent recovery.
- Minimizes environmental impact with a closed-loop system that conserves and recycles solvents.
- Optimizes space and workflow efficiency with its compact design and integrated trolley.
- Supports versatile solvent and water mixture handling when paired with the Dehumidifier S-396.
- Applications
- Chemicals,Food,Vitamins,Proteins,Materials,Fragrances,Nutraceuticals,Cosmetics,Functional foods,Probiotic bacteria,Milk powder,Biotech,Flavors,Juice concentrate,Batteries,Pharmaceuticals
- End products
- Functional food powders,Aroma-encapsulated beads for cosmetics,Solid dispersions for increased solubility,Battery electrode materials,Multivitamin compounds,Juice concentrate powders,Milk powders for reconstitution,Paint pigments,Protein supplement powders,Encapsulated flavors in the food industry,Nano-drug formulations,Fragrance microcapsules,Probiotic supplement powders,Biodegradable microspheres for cell encapsulation,Inhalable powders for asthma,Solid oral dosage forms,Catalysts for chemical reactions
- Steps before
- Solvent preparation,Sample loading,Degassing,Formulation mixing
- Steps after
- Solvent recovery,Dry powder collection,Product analysis,Quality control testing
- Input ingredients
- organic solvents,liquid solutions,suspensions,water and solvent mixtures,additives,nutraceuticals,functional foods,flavors,vitamins,proteins,probiotic bacteria,juice concentrate,milk,cells,bacteria,fragances,nano materials,paints,coatings,catalysts,electrode materials
- Output ingredients
- dry powders,submicron particles,solid dispersions,inhalable drugs,taste-masking particles,controlled-release formulations,nano structured materials,uniform particles,high-performance coatings,encapsulated cells,encapsulated bacteria,encapsulated proteins,cosmetics
- Market info
- Buchi is renowned for its expertise in laboratory and industrial solutions, particularly in producing high-quality equipment for chemical analysis and lab processes, known for precision and reliability in the pharmaceutical, chemical, and food industries.
- Inert gas consumption
- Low
- Explosion safety
- Inert gas atmosphere
- Cooling temperature
- -30 °C
- Installation type
- Fast / Integrated trolley
- System configuration
- Closed-loop
- Pressure control
- Yes
- Safety in Spray Drying
- Explosion free due to inert gas atmosphere
- Pollution Control
- "Closed loop" approach minimizes pollution
- Cooling Circuit
- Recovers organic solvents (-30 °C)
- Compatibility with Dehumidifier
- Optional combination with Dehumidifier S-396
- Installation Time
- Fast installation
- Space Efficiency
- Integrated trolley for space saving
- Solvent Recovery
- Recovers organic solvents
- Gas Consumption
- Low consumption of inert gas
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Spray drying compatibility
- Mini Spray Dryer S-300
- Compact footprint
- Space-saving due to integrated trolley
- Cooling temperature
- Cooling circuit recovers organic solvents (-30 °C)
- Discharge method
- Closed loop
- Installation type
- Fast installation
- Integration Possibilities
- Dehumidifier S-396 integration
- Space saving design
- Integrated trolley
- Safety Features
- Explosion free due to inert gas atmosphere
- Environmentally Sustainable Design
- Closed loop system
- Cooling System
- Cooling circuit at -30 °C