High-pressure homogenizer for small-scale production
Enhance your liquid formulations with precise particle size reduction and improved stability, ensuring superior bioavailability and consistent quality from bench to small-scale production.
Processes Nanoemulsions and Reduces Particle Size
The Mini DeBEE from Pion is a high-pressure homogenizer designed for biotech and pharmaceutical applications, uniquely bridging R&D and small-scale production needs. Operating at pressures up to 45,000 PSI, it excels in producing nanoemulsions and uniform particle sizes, vital for effective liposomal vitamin C supplements and injectable insulin solutions. Handling up to 4.0 GPH, it integrates seamlessly into production lines with programmable pressure control and flow optimization. Its stainless steel construction ensures compatibility with rigorous industry standards, and it supports CIP for efficient cleaning. The unit’s scalability guarantees consistent results from laboratory to industrial settings, backed by comprehensive engineering support for customization.
Benefits
- Enhances formulation efficiency with high-yield cell lysis and tighter particle size distribution.
- Increases product stability and bioavailability, crucial for pharmaceuticals and nutraceuticals.
- Facilitates scalability from R&D to full-scale production without performance loss.
- Streamlines operations with flow capacity up to 5.3 GPH, boosting productivity.
- Ensures compliance with stringent industry standards, suitable for sensitive biotech applications.
- Applications
- Biopharmaceuticals,Liquid formulations,Nutraceuticals,Pharmaceuticals
- End products
- Vaccine suspensions,Injectable insulin solutions,Antibody formulations,Stabilized omega-3 fish oil,Protein dissolutions,Liquid medications for pediatric use,Nanoemulsified cbd oil,Transdermal hormone creams,Liposomal vitamin c supplements,Microencapsulated probiotics
- Steps before
- Cell Preparation,Initial Formulation,Pre-mixing,Ingredient Mixing
- Steps after
- Particle Analysis,Product Stability Testing,Final Formulation Adjustment,Quality Control,Packaging
- Input ingredients
- cell suspensions,emulsions,dispersions,particles
- Output ingredients
- high-yield cell lysate,nano emulsions,particle size-reduced materials,stable micro/nano dispersions
- Market info
- Operating pressure
- 2,000 - 30,000 PSI or 2,000 - 45,000 PSI
- Flow rate
- Up to 4.0 GPH (15 LPH) at 45,000 KPSI
- Flow rate
- Up to 5.3 GPH (20 LPH) at 30,000 KPSI
- Working Pressure
- 2,000 - 45,000 PSI
- Flow Rate
- Up to 5.3 GPH (20 LPH)
- Scalability
- Direct scalability
- Operational Phase
- R,D to Small-scale Production
- Process Intensity
- Highest in the Industry
- Application Flexibility
- Cell lysis,nanoparticle dispersions
- Batch vs. Continuous Operation
- Batch
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Cell lysis efficiency
- High-yield
- Particle size reduction
- Tighter distribution
- Emulsification
- Stable micro / nano emulsions
- Compact Footprint
- N/A
- Control Panel Type
- N/A
- Discharge Method
- N/A
- Scalability
- Direct scalability from R,D to production
- Process intensity
- Highest in the industry