Online moisture control for lyophilized pharmaceutical products
Ensure precise moisture control in lyophilized products with real-time, non-destructive analysis, optimizing product quality and stability without halting production.
Measures Residual Moisture in Lyophilized Products
The LYOSENSE® system from GEA offers precise real-time moisture measurement for lyophilized products using multipoint NIR technology. Designed for pharmaceuticals and biotech, it accurately evaluates residual moisture in products like vaccines and therapeutic proteins. Easily integrates into processing lines with its simple, non-invasive operation. The mobile LYOSENSE® STATION extends versatility, facilitating moisture assessment in glass vials with its robust and maneuverable design. Capable of inspecting up to 100 vials per minute, it ensures compliance with industry standards by automating the rejection of out-of-specification units. Configurable for specific vial sizes, it supports Quality by Design initiatives, packaged with full documentation and compliance verification under European CE guidelines.
Benefits
- Ensures precise product quality by providing non-destructive, real-time moisture measurement.
- Increases operational efficiency with rapid analysis at speeds of up to 100 vials per minute.
- Enhances product integrity by automatically rejecting out-of-specification vials.
- Facilitates mobility within production areas with a compact, maneuverable design.
- Supports regulatory compliance with comprehensive testing and documentation.
- Applications
- Lyophilized products,Vaccines,Freeze-dried product cakes,Pharmaceuticals
- End products
- Biologics,Monoclonal antibodies,Biopharmaceuticals,Lyophilized therapeutic proteins,Freeze-dried plasma,Pharmaceuticals like antibiotics,Diagnostic reagents
- Steps before
- Lyophilization,Freeze Drying,Pharmaceutical Vial Loading
- Steps after
- Residual Moisture Inspection,Vial Packing,Quality Control
- Input ingredients
- pharmaceutical glass vials,lyophilized products,freeze-dried product cakes
- Output ingredients
- residual moisture content measurements,quality assurance data,real-time evaluation results
- Market info
- GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.
- Moisture Content Accuracy
- 0.2–5.0% water content
- Measurement Speed
- 5 ms
- Vial Inspection Speed
- Up to 100 per minute
- Vial Diameter Range
- 16.25–33.00 mm
- Automation
- PLC-controlled
- Sensor Type
- Multipoint NIR
- Operation
- Single person operation
- Calibration
- Simple and easy
- Installation Type
- Online measuring device
- Probe Size
- Miniaturized
- Automation Level
- Automated NIR Analysis
- Process Integration
- Non-invasive Measurements
- Data Handling
- Connected to External Computer
- Mobility
- Mounted on Wheels
- Speed Control
- Integrated Touchscreen
- Measurement Speed
- 5 ms
- Calibratability
- Easy Calibration
- Vial Inspection
- 100% Inspection Rate
- Residual Moisture Range
- 0.2–5.0% Water Content
- Rejection System
- Out-of-spec Vials are Rejected
- User Interface
- Simple and Easy
- Vial Size Compatibility
- 16.25–33.00 mm
- CE marking
- Yes
- Machine footprint
- 900 mm width
- Handling
- Mounted on wheels
- Vial size compatibility
- 16.25–33.00 mm
- Control panel type
- Integrated touchscreen
- Integration possibilities
- Computer interface
- Mobility
- Mounted on wheels
- Single person operation
- Yes