High-shear mixer granulator for pharma and nutraceuticals
Optimize your batch and high-speed production with a powerful granulator designed to ensure precise particle size distribution and uniformity, essential for achieving consistent quality in tablet and capsule manufacturing.
Performs High-Speed Granulation and Mixing
The HSM 2000 X·ONE from ACG is a high-shear mixer granulator engineered for precision and efficiency in large-scale batch processing of pharmaceutical and nutraceutical products. Its unique design features a Z-shaped impeller and multi-blade chopper, optimizing centrifugal force for uniform binder distribution and minimizing dead zones. This equipment excels in wet granulation and mixing, ideal for producing tablet granules, vitamin supplements, and probiotic capsules.
Capable of handling working volumes from 600 to 1,600 liters, it integrates seamlessly into a granulation train or operates as a standalone unit. The system is equipped with the ACG X·ONE command process control system, providing secure, intuitive monitoring compliant with ATEX, GAMP 5, and 21 CFR Part 11 standards. The MOST™ (Maximum Operator Safety Technology) ensures operator safety, while the non-vented, fully contained design enhances the work environment.
It supports applications in processing departments within the pharmaceutical and nutraceutical industries, handling powders and granules with high-speed efficiency. Maintenance is streamlined with wash-in-place (WIP) systems, facilitating easy cleaning and reducing downtime for continuous operation.
Benefits
- Enhances production efficiency by ensuring uniform particle-size distribution and content uniformity.
- Minimizes safety risks and production delays with a 12-bar pressure shock-resistant system.
- Reduces cleaning time and improves productivity with wash-in-place (WIP) capabilities.
- Offers regulatory compliance and secure process monitoring with integrated ATEX, GAMP 5, and 21 CFR Part 11 systems.
- Adapts seamlessly to both standalone operations and integrated granulation trains for flexible production setups.
- Applications
- Vitamins,Supplements,Fine chemicals,Nutraceuticals,Pharmaceutical powder,Biopharmaceuticals
- End products
- Pain relief granules,Probiotic capsules,Collagen peptides,Dietary supplement powders,Herbal supplement granules,Tablet granules,Enzyme supplements,Pharmaceutical excipients,Amino acid supplements,Vitamin granules
- Steps before
- Weighing,Pre-mixing,Pre-granulation
- Steps after
- Drying,Mill sieving,Blending
- Input ingredients
- powdered ingredients,binder
- Output ingredients
- granules,uniformly mixed dry compositions
- Market info
- ACG World is known for its expertise in manufacturing pharmaceutical and nutraceutical processing and packaging machinery, offering innovative equipment solutions and maintaining a strong reputation for quality and reliability in the global market.
- Working Volume Min
- 600 l
- Working Volume Max
- 1,600 l
- Pressure Shock-Resistance
- 12-bar
- Compliance
- ATEX (Directive 2014/34/EU),GAMP 5,21 CFR Part 11
- Impeller Type
- Z-shaped impeller
- Discharge and Charging Systems
- Multiple systems available
- Control System
- ACG X•ONE command process control system
- Binder Distribution
- Uniform binder distribution
- Automation level
- PLC / SCADA
- Batch vs. continuous operation
- Batch
- CIP/SIP
- Wash-in-place (WIP)
- Cleaning method
- Wash-in-place (WIP)
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- ATEX certification
- Directive 2014/34/EU
- Pressure shock-resistant
- 12-bar
- Bowl geometry
- Unique product bowl geometry
- Impeller shape
- Z-shaped impeller
- Chopper type
- Multi-blade chopper
- Pressure shock resistance
- 12-bar
- Working volume
- 600 l - 1,600 l
- Design type
- Non-vented,fully contained design
- Safety concept
- MOST™ (Maximum Operator Safety Technology)
- Control panel type
- ACG X•ONE command process control
- Integration possibilities
- Granulation train or standalone unit
- Safety features
- MOST™ (Maximum Operator Safety Technology)
- Charging and discharging systems
- Multiple systems for efficient handling
- Cleaning options
- Wash-in-place (WIP)