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Vaccine Manufacturing Equipment

Find innovative production technology for making vaccines and connect directly with world-leading specialists.

Vaccine making equipment

Some of the vaccines in use today were originally developed decades ago. But advances in research, expertise and vaccine development equipment provide immunizations from bacterial and viral diseases (antibodies and cell therapy) to more people every year. The Covid 19 pandemic highlights the urgent need to scale up the production of vaccines and ensure an automated as well as reproducible manufacturing environment.

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Sterile Filtration System for GMP-grade products

Sterile Filtration System for GMP-grade products

Processing equipment used in industries regulated by GMP must ensure fully…

High-frequency vibratory mixer

High-frequency vibratory mixer

Mixing liquid products by stirring method generates heat from friction and shear forces. This …

GMP dispersing machine for liquid formulations

GMP dispersing machine for liquid formulations

Multi-staged rotor/stator mixers generate the high shear forces required to …

Agitator bead mill for API

Agitator bead mill for API

To achieve precisely defined API properties and safe and reproducible production, rigorous impleme…

Flexible laboratory bead mill for vaccines

Flexible laboratory bead mill for vaccines

For precise, efficient, and reproducible cell disruption, optimization of proces…

Disposable isolator

Disposable isolator

Pharmaceutical powders need to be contained in the strictest conditions. But handling powders and cleaning…

Aseptic filling machine for liquids and powders

Aseptic filling machine for liquids and powders

Aseptic filling of containers such as vials, syringes, bottles, and cartrid…

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Manual stoppering equipment for pre-filled syringes

Manual stoppering equipment for pre-filled syringes

Air present in the empty space of pre-filled syringes may prevent you …

Manual ampoule filler

Manual ampoule filler

When you fill ampoules it is essential to avoid wetting the inside walls of the container, as it may aff…

Laboratory liquid viewer for transparent glass bottles

Laboratory liquid viewer for transparent glass bottles

Impurities like hair, fibers, or glass, sourced from the environmen…

Laboratory liquid viewer for varying light conditions

Laboratory liquid viewer for varying light conditions

In the pharmaceutical industry, you must inspect liquids in vials or…

Laboratory liquid viewer for colored glass bottles

Laboratory liquid viewer for colored glass bottles

In the pharmaceutical industry, an inspection to detect any particulate…

Benchtop ampoule opening and closing equipment

Benchtop ampoule opening and closing equipment

The procedure for opening or closing ampoules requires you to handle gas and…

Automatic forming and sealing blister machine for packing syringes

Automatic forming and sealing blister machine for packing syringes

Controlling contamination is on every manufacturer's …

Automated bubble traps for chromatography

Automated bubble traps for chromatography

Radial flow chromatography processes require special attention and the right use …

Pre-packed and pre-validated chromatography columns

Pre-packed and pre-validated chromatography columns

In chromatography, you must always take into account the apparatus tha…

Lab-scale radial chromatography columns for virus validation

Lab-scale radial chromatography columns for virus validation

In the food industry, as an example, during lab-testing and …

Low speed Filler for large-volume parenterals

Low speed Filler for large-volume parenterals

Large-volume parenteral bottles are usually manufactured with a resin that ca…

Form fill seal thermoforming machine for medical devices

Form fill seal thermoforming machine for medical devices

Form Fill Seal thermoforming machines are those that produce pack…

Labeling machine for ampoules

Labeling machine for ampoules

It’s essential for pharmaceutical companies to provide the highest quality ampoules to custome…

Pharmaceutical rotary labeling machine for vials

Pharmaceutical rotary labeling machine for vials

Small, cylindrical-shaped glass bottles or vials are mainly used for vacci…

Complete bioreactor system

Complete bioreactor system

An autoclavable bioreactor establishes special conditions for a variety of applications, for examp…

Optical Dissolved Oxygen Sensors

Optical Dissolved Oxygen Sensors

Sufficient oxygen is critical to the success of processes like cell culture and fermentation…

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Bioprocess control software

Bioprocess control software

Managing a large number of bioprocesses individually without automation is time-consuming, and th…

Bioreactor software

Bioreactor software

Comprehensive upstream data acquisition and management are essential in the bioprocessing industry. That’…

Single use bioreactor

Single use bioreactor

Single use, micro-bioreactors could be a good solution for replication processes, especially when they e…

Sterile compounding system

Sterile compounding system

Hospitals and compounding centres have traditionally used manual aseptic compounding processes. As…

Closed restricted access barrier system

Closed restricted access barrier system

Pharmaceutical production techniques often require isolation of compounds and chemic…

Nested syringe filling machine

Nested syringe filling machine

Increasingly, pre-sterilized Ready To Use (RTU) nested vials, cartridges and syringes are the …

Syringe tub sterilizer

Syringe tub sterilizer

A common challenge is how to transfer nested syringe tubs to the aseptic filling area without compromis…

Vial filling machine

Vial filling machine

The volume filling of vials, cartridges and syringes is a vital part of the production of a wide range of…

Vial sterilization tunnel

Vial sterilization tunnel

Sterilization of vials, ampoules and syringes before filling is a vital step in the production of r…

Packaging machine for syringes in trays

Packaging machine for syringes in trays

Pre-dosed syringes are rapidly becoming the method of choice for the delivery of inj…

Distributor of samples to different devices

Distributor of samples to different devices

The ability to expand your automatic sampling solution provides increased flexi…

Flexible automatic inspection machine for syringes

Flexible automatic inspection machine for syringes

Manufacture of pre-filled syringes requires the highest quality inspect…

Stories about Vaccines

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Vaccines are over-formulated to protect against potency loss


Vaccines start with the isolation of chemically defined media, but they come into being during formulation. The delicate development process stabilizes the separate components into a uniform mixture and prepares it for batch dosing. Cell cultures are often used in the development as well as formulation of Vaccines and has been that way for decades.


When it comes to producing vaccines, mixtures are typically over-formulated above the required potency. This method lowers yield but compensates for any possible degradation throughout the vaccine’s shelf-life.


Reduce vaccine moisture to max 3% with freeze-drying equipment

The process of lyophilization ensures that your biological formula remains stable along the cold chain. For this reason, freeze-dryers have become critical equipment in modern vaccine production.

Vaccine freeze-drying is a complex procedure involving three major steps. At the freezing stage, the solution solidifies with the formation of crystals. During the dehydration phase in a drying chamber, you subject the material to temperatures not exceeding -50 °C and forces water to sublimate. Finally, another round of drying releases any remaining moisture to between 1% and 3%.

Protect diluent from freezing or heating with cold chain storage

Before clinical trials and before the vaccine enters into the arms of patients, your lyophilized vaccines are reconstituted into liquid solutions using a diluent. World Health Organization guidelines warn that vaccine manufacturing is incomplete without the accompanying diluent.

Sterile water is often used as a diluent, but ingredients may contain a range of other substances such as sodium chloride, xanthan, or calcium carbonate. Whatever the composition, diluents must always be kept at temperatures between +2°C to +8°C.

Chromatography technology and mRNA techniques promise more accessible vaccines


Purification of the reaction mixture remains a challenge for large-scale vaccine development and production. But chromatography is emerging as an ideal purification technique for several biopharmaceuticals.  Ligands in the chromatography columns form ‘hooks’ that filter out specific contaminants.


Vaccine manufacturers are taking advantage of this purification technique to reduce vaccine production’s financial and environmental costs. This method is attracting particular interest with the development of mRNA vaccines to combine a relatively simple manufacturing process with the high-yield capabilities of chromatography.


Packaging is a crucial step in vaccine production. This step is often forgotten about but is important in ensuring that the vaccines reach their final destination without getting damaged. But more importantly, safe packing means that the vaccines will reach patients without getting contaminated.


Processing steps involved in vaccines making

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