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flexible-containment-solution

Flexible-containment-solution

The essential objectives of containment systems are personnel protection and preventing the release of toxic or infectious material into the environment. Containment is also used to prevent a product or sample from contamination by the external environment. In the chemical and pharmaceutical industries, containment solutions are used to protect the personnel from the leaking of airborne particles of hazardous substances, as powders or liquids are handled or transferred during processing.

Containment

Herbs have always been shrouded in mystery. The delicate plans produce overpowering bouquets and potent remedies. Herbal extraction technology gets to the core of this mystery and makes bioactive compounds available for a range of applications. Rich in antioxidants, anti-inflammatories, and aromas, herbal extracts are vital ingredients for medicines, foods, cosmetics, and wellness products.

Herbal extracts

Healthcare products are goods or services used to improve, maintain or prevent the deterioration of health or ease the consequences of illness. Healthcare products include a wide range of goods, from hospital clothing, over plasters, wound care products and diagnostic devices. These products must be clean and contamination-free, which is achieved with strictly regulated healthcare equipment.

Healthcare products

A flexible containment solution prevents product loss and ensures that personnel is not exposed to harmful substances by locking in the product as it is transferred from one container to another. The choice of a containment system depends on the physical state of the product, the type of container from which the product is being transferred, and the type of container to which it is being moved. Flexible containment solutions are widely used in the pharmaceutical, food, and chemical industries to comply with health and safety regulations.

Industrial

In pharmaceutical manufacturing, maintaining aseptic conditions while filling and closing sterile bags is crucial. Traditional methods often face challenges in achieving consistency and minimizing human intervention, which can introduce contamination risks.
<h2>Automates liquid and powder filling processes</h2>
The SMART DB2 by IMA Life is a sterile bag filling and closing system designed for high-speed pharmaceutical applications. Working with flexible materials, it addresses non-repeatability issues in aseptic processes. It fills multi-chamber, Ready-To-Use sterile bags with both powder and liquid products using dosing disks for powders and mass-flow technology for liquids. The integrated CIP SIP system ensures thorough cleaning and sterilization in place, reducing the need for part removal and autoclaving. The system can fill up to 42 bags per minute, with volumes of 50ml for liquids and 3.5 grams for powders. The entire line operates under isolation technology to avoid contamination, and features automated weighing and robotic technologies to minimize operator intervention.

Sterile bag filling and closing system

Industrial cleaning equipment is used to wash or disinfect machinery and the production/warehouse area. It may also be used to sterilize the product, equipment, tools, floor or work surfaces and to purify or clean the product by removing impurities. Choosing a suitable cleaning system depends on the type of product or equipment to be cleaned, the sensitivity of the product to heat, pressure, and chemicals, and the level of sterility desired.

Cleaning

Dosing systems are a line of hoppers, feeders, filling machines, and checkweighers that operate in sync to dispense materials accurately. Dosing is an essential feature of the packaging process, whether you’re filling shampoo bottles or tea bags. But dosing equipment is critical for formulations, too, particularly in the pharmaceutical and chemical industries. Imprecise dosing may cause quality degradation in the best-case scenario. In the worst scenario, it creates serious health risks.

Dosing

Filling lines are used extensively in all industries, such as food, pharmaceutical, chemical, and cosmetics, to accurately package different products into a container suitable for that product. Although the filling process is at the very end of the production line, it is no less important than the earlier steps. Last but not least, the idiom that dates back to 1382 when John Wyclif wrote the firste the laste, and the laste the firste, indicates just that the last things on a list are just as valuable as the previous ones. In this case, this idiom fits perfectly.

Filling

Industrial sterilization processes are employed in different industries to completely eliminate all living microorganisms from the final product. For instance, in food processing, sterilization equipment is used to produce a stable product with a long shelf-life by eradicating harmful bio-contaminants. Instead, in the medical field, sterilization technologies aim to prevent the transmission of microbes to patients by sterilizing all the tools and medical devices that come in contact with the patient. Most sterilization equipment, such as autoclaves, employs high-temperature pressurized steam to destroy bacteria and disinfect surfaces from spores. Other methods include radiation sterilization or using chemicals such as hydrogen peroxide for disinfection.

Sterilization

Weighing

liquid

Powder

solid

In food production, particularly in dairy and edible fats, precision in dosing and efficient wrapping are critical for maintaining product integrity and operational efficiency. Challenges include achieving accurate portion sizes and ensuring the product is securely wrapped for distribution.
<h2>Precisely fill and wrap pasty products</h2>
The MULTIPACK 3000 by IMA is a single-cell system designed for filling and wrapping pasty products such as butter, margarine, and fresh cheese. This system offers an exceptional dosing range from 50 to 1000 grams with a high accuracy of s=0.3 g for Qn < 250 g. The flexible design allows for different folding options including brick, cube, rolls, round, and oval shapes. Notable features include servo-driven main drive, individual servo-drives for wrapping material feed, and options like CIP cleanable dosing unit and remote access control. The MULTIPACK 3000 can output up to 100 packets per minute and utilizes various wrapping materials like parchment, aluminum laminated foil, and plastic coated papers. It is ideal for food and dairy applications aiming for high efficiency and low product waste.

Filling and wrapping system for pasty products

Wrapping is the final step before your finished products are ready to leave the manufacturing site. Packages are bundled tightly together with a low-density polyethylene wrapper to secure the goods inside during transportation and distribution. Automatic or semi-automatic stretch wrapping machines cloak the palleted load in expandable film at high speeds and precision.

Wrapping

In the confectionery industry, presenting coated sweets attractively in supermarkets is crucial for quick and efficient shelf placement. Traditional methods often fail to ensure the visual appeal and security of the products during transport and presentation.
<h2>Efficiently pack and present coated sweets</h2>
The WA by IMA is a high-speed wrap-around case packer designed specifically for coated sweets. It offers a versatile and flexible packaging solution by accommodating a wide range of product types and shapes, such as bags and cartons. The WA ensures that each product is carefully and securely packaged, whether standing or lying down, in one or more rows and layers. The system includes accelerating belts to feed products separately, which are then grouped into cases and positioned on a flat case blank. Subsequently, the case blank is folded around the grouped products, and the cover is closed and secured with hot glue. The WA also allows for quick and reliable format changeovers using customized format kits and spindle adjustments. It supports sustainable practices by using recycled cardboard. The equipment has a line speed of 1100 products per minute and can pack up to 30 boxes per minute. It operates with a power requirement of 26 kW and an exercise pressure of 6 bar, and weighs approximately 3000 kg. The WA is an excellent solution for enhancing the presentation of coated sweets in supermarkets, provided by IMA.

Wrap-around case packer for coated sweets

Conveyor systems are used for moving materials from one location to another. Considerations for choosing a suitable industrial conveying system include the nature of the product, its physical state, the desired conveying rate, and sensitivity of the product to heat and mechanical shock. Conveying equipment is used in the food, pharmaceutical, chemical, biomass, and mineral industries to move materials around a warehouse as well as to transport bulk powders, granules, and grains for processing and filling. These types of systems are usually automated and there is a wide variety of solutions to choose when it comes to the type of conveyor. Types include screw, gravity, chain, roller and belt conveyors.

Conveying

Industrial feeding systems allows you to control the flow of solid bulk materials throughout the manufacturing line. After loading your material onto the vibrating hopper, a screw at the base drives it out in uniform doses to the next stage of processing. New feeding technologies are designed to deal with challenges of powders clumping together in the hopper (bridging and ratholing) that interrupt the outflow. Common feeder systems include centrifugal feeders, vibratory feeders as well as elevator, linear and pneumatic feeders.

Feeding

The process of forming allows you to shape your products homogeneously. Forming machines are fed the manufactured material in bulk and cut it down to specification, so the process takes place between formulation of the mass and the packaging of the final item.

A special class of this equipment – Form, Fill, and Seal Machines (FFS) – creates bags and pouches from flat material such as plastic sheets, fills them with your designated product, and seals them.

Forming

<span style="font-weight: 400">At last, you reached the final stage of processing your product - welcome to the packing world! Packing preserves and protects a product from damage, spoilage, and contamination while it makes its way from the production line to the consumer or further production. Depending on which industry your products belong to, the type of primary packaging equipment can change drastically. You need to pay careful attention to products with </span><span style="font-weight: 400">chemicals or hazardous substances since they can be potentially dangerous to human health. </span>

Packing

Sealing

Batch

In research and development, precise handling of ultra-small batches of powders or suspensions often poses significant challenges. Accurate size reduction, classifying, or mixing of quantities as small as a few grams is required to produce reliable results.
<h2>Process ultra-small batches with modular flexibility</h2>
The Picoline series by Hosokawa Alpine is a modular lab-scale system specifically designed for handling small quantities of powder or suspension. It consists of a platform combined with eight interchangeable function modules and various accessories. The table-top design features a housing made of brushed stainless steel, making it suitable for clean environments like laboratory fume hoods. The touch panel control system, with an integrated microprocessor, allows easy switching and control of different function modules. This ensures that processes can be quickly set up, controlled, and adjusted with visual feedback. The system supports LIMS integration and USB data export. The Picoline series is ideal for laboratories needing to process mini batches for R&D purposes, offering scalable results that can be transferred to larger process equipment with ease.

Lab-scale powder processing system

Classifying

Industrial mixing equipment is used to combine two or more solid, liquid or gaseous segregated ingredients into a homogenous single product. The choice of mixing technology depends largely on the physical state of the ingredients and the desired final product. But the sensitivity of the ingredients, the process temperature, and pressure requirements are also critical factors. All these parameters result in a wide range of industrial mixers.

Mixing

Industrial separation equipment encapsulates the separation process which is to separate components of a liquid mixture, for recovering dissolved solids from liquids. The choice of a suitable technology depends on the identification of the key physical or chemical property, such as size, mass, density, or boiling point, which sets the product of interest apart from the rest of the components. Separation technology is widely used in the pharmaceutical and chemical industries for the isolation of active ingredients and high-purity chemicals. As well as in waste management and recycling industries.

Separation

Sieving machines are available in various designs such as linear sieves, tumbler sieves, and vibrating sieves each employing a different sieving action. The choice of a suitable sieving machine depends on the desired particle size distribution, required amplitude and frequency of vibrations, and the physical state of the mixture. Sieving machines are used for removing dust from granular products and for grading grains. They are also used for the classification of granular material and the separation of solids from a slurry mix in the food processing industries.

Sieving

Sorting is the process of arranging items systematically, using a specified criterion, to categorize and group similar items and identify non-conforming items for removal. The choice of a sorting machine depends on the type of item to sort, the sorting criteria, the number of categories that the items need to be sorted into, sorting speed, and accuracy. Sorting machines can be used in the food processing industry for sorting and categorizing fruits, vegetables, empty bottles, crates, and other items; other examples include sorting of tablets and capsules by weight for quality control in the pharmaceutical industry. As well as sorting waste in the recycling industry. Manual sorting is a laborious task however, with the use of specialized equipment, manufacturers are able to automate their sorting at high speeds.

Sorting

Continuous

Industries like heavy manufacturing and fine chemicals often require reliable methods for moving bulk materials efficiently. Challenges arise with material consistency, dust control, and potential hazards, necessitating effective mechanical conveying solutions.
<h2>Efficiently move and manage bulk materials</h2>
Hosokawa Solids offers a range of mechanical conveying systems designed to meet various industrial needs. Their rotary valves and screw conveyors are notable for precise dosing, feeding, and discharging of fine-grained and dusty products or granulates. Available in three design lines – solids Basic, solids Clean, and solids Hygienic – these systems cater to different operational requirements. Rotary valves come in diverse types such as the ZRS for low pulsation dosing and the SRVP for explosion protection. Screw conveyors, including tubular and trough screws, offer flexibility with full-bladed or shaftless designs. Materials vary from mild steel to wear-resistant alloys, ensuring durability under different conditions. Hosokawa Solids Solutions, part of Hosokawa Alpine Group since 2020, ensures optimal selection and customization based on specific product properties and tasks.

Mechanical conveying systems for bulk solids

Discharging

In many industrial processes, handling bulk materials involves the challenge of efficiently emptying material containers. Manual unloading can be labor-intensive and time-consuming, resulting in productivity loss. The solution often requires a streamlined and adaptable system to facilitate this task effectively.
<h2>Facilitates easy container unloading</h2>
The MCED Material Container Emptying Device by Hoopman Equipment is designed to simplify the unloading of material containers used in conjunction with various fluid bed dryers and related systems. This device comes with standard mounting options, including units that can be easily attached to walls or building ribs. The system includes an electrical lifting mechanism to lift and tilt the containers, allowing for smooth and efficient emptying of contents. It is compatible with different seed bins through available adapters. This adaptable solution ensures that material handling is streamlined and ergonomic, reducing the need for manual labor and associated risks. Suitable for various industries, this device offers a practical approach to improving efficiency in material management.

Material container emptying device

Handling

In medical and pharmaceutical manufacturing, efficient assembly of complex devices like autoinjectors and inhalers is crucial. The challenge lies in achieving high precision and output while handling multiple components and marking requirements, often within stringent cleanroom conditions.
<h2>Automate assembly with precision and flexibility</h2>
The MQT by Harro Höfliger is a fully automatic system designed for assembling various medical and pharmaceutical devices. Its servo-controlled drive ensures maximum flexibility, allowing for stations that handle dosing, lasering, and labeling. This system achieves an output of up to 160 products per minute. The MQT platform supports products like autoinjectors, pens, inhalers, safety devices, patch injectors, and patch pumps. Additional features include precise product transport with high-speed capabilities and a range of camera systems for verification. The MQT can seamlessly integrate with other technology platforms and packaging machines. It offers cleanroom versions up to Cleanroom class 1000, ideal for high-quality and sensitive production environments.

Servo-driven device assembly system

Assembly platforms combine different parts into one final product. Components are inspected for quality and joined or affixed together into the goods. Assembly lines automate the process to ensure consistent quality and integrate into other technologies, such as packaging equipment. But a primary consideration for assembly solutions is their capacity to scale manufacturing processes. Assembly platforms must be adaptable to your long-term volume requirements.

Assembling

Labels provide customers with important information about both your product and your brand. Different labeling technology attaches the printed film to the packaging using a range of methods such as shrink wrapping, side sealing, and adhesives. For added traceability and protection, you may also use serialization coding equipment and anti-tampering labeling systems.

Labeling

In aseptic processing environments, maintaining product sterility during packaging is critical. Traditional methods can involve complex, multi-step processes prone to contamination. This challenge is particularly significant when handling sealed tubs containing products like RTF syringes or vials that require stringent protection.
<h2>Ensures sterile double bagging of sealed tubs</h2>
The TBS from Harro Höfliger is a specialized double bagging solution designed for aseptic environments. Operating under ISO 7 clean room standards, this system ensures that tubs sealed with Tyvek are inserted into pre-opened bags and tightly sealed. This process can be repeated to place an already bagged tub into an additional bag, offering enhanced protection. The compact design supports different operational speeds—Low, Mid, and High Speed—while maintaining low-particulate process technology. With an output capacity of 4 single-bagged tubs per minute and 3 double-bagged tubs per minute, the TBS guarantees efficient and reliable packaging for RTF syringes and vials.

Double bagging solution for sealed tubs

Bagging is the process of packaging measured portions of a product into bags that protect it from spoilage, enable easy and safe transportation, and secure the product against tampering and pilferage. The choice of bagging equipment depends on the desired mass or volume per bag, the flow characteristics of the product, and bag construction and design. Bags vary in size from small sachets to bulk flexible containers. Bagging systems are often the last processing step that is generally integrated into a production line.

Bagging

In pharmaceutical manufacturing, maintaining sterility and precise dosing during packaging is crucial to ensure product efficacy and compliance with industry standards. Consistency and accuracy in filling and sealing processes are necessary to meet these stringent requirements.
<h2>Ensures precise dosing and secure sealing</h2>
The PPH system by Harro Höfliger is designed for the production and filling of four-edge sealed bags with pharmaceutical powder and bulk goods. The packaging film is printed in-line and transported for three-edge sealing. Bags then undergo a dosing process with 100% weight inspection before final sealing. This system ensures high precision in dosages ranging from 1 mg to 500 mg, across three dosing stations. The complete process occurs within a GMP-compliant, protected production room. Integration of micro-dosing systems and the ability to manufacture various product variants make the PPH suitable for diverse pharmaceutical applications. The downstream cartoning machine further packages the bags into folding boxes, ensuring a seamless production workflow.

Pharmaceutical powder bag filling system

Blending

In pharmaceutical production, accurately weighing capsules at high speed is essential for maintaining product consistency and quality. Ensuring that each capsule meets stringent weight specifications prevents issues related to under or overfilling, which is critical for both efficacy and regulatory compliance.
<h2>Achieve precise and rapid capsule weighing</h2>
The Accura-C is a capsule weighing system from Harro Hoefliger designed for high-performance quality inspection. This system weighs pharmaceutical capsules gently yet precisely, ensuring bad capsules are reliably sorted out. The integrated feedback loop allows automatic regulation of capsule filling weight. With an in-line connection to capsule filling machines, including those from other manufacturers, it increases production efficiency. The system features vibration compensation for highly precise weighing results, and minimal setup and cleaning times, making it highly reliable for continuous operation. It supports all common capsule sizes, and works with a measuring range of 0 – 2,000 mg with an accuracy of ± 2 mg.

High-speed capsule weighing system for quality assurance

Industrial inspection equipment is used for checking compliance with health, safety, and quality control standards. For that reason, inspection systems are most commonly utilized in the food and pharmaceutical industry but, they are also used in other industries too. Inspection solutions are often integrated into a production process or production line. Visual inspection systems perform checks to detect variation in size, shape, and color and ensure the presence of labels and closures. Check-weigh systems help ensure that product packages are not under or over-filled. Metal detection systems can help guard against the presence of foreign objects in product containers and X-ray inspection equipment is used to detect physical defects and to ensure high quality package seal integrity.

Inspection

Handling and transporting tablets in the pharmaceutical industry requires precise methods to avoid breakage and contamination. Ensuring the tablets remain intact and uncontaminated during storage and transport is crucial for maintaining product efficacy and meeting regulatory standards.
<h2>Store and transport tablets safely</h2>
The Tablet IBC by Hanningfield Process Systems is a specialized container designed for the gentle handling of tablets. Featuring a shallow body angle and a flexible-vane outlet valve, it minimizes the risk of tablet breakage and damage. Constructed from 316L stainless steel for all contact parts and equipped with FDA-compliant seals, it ensures safe and sanitary conditions. Non-contact parts are manufactured from 304 stainless steel, and the design can be customized with features such as castors for mobility, corner stacking profiles, and lifting loops for handling via forklift or post hoist. The tablets can also be transferred into a coater using an outlet chute. These containers are suitable for validatable cleaning processes using a wash booth or wash station. Hanningfield's Tablet IBCs are ideal for the pharmaceutical, food, and allied industries.

Tablet storage and transport containers

Almost all manufacturers will require industrial storage systems and solutions at some point during their production process. The raw materials that go into your products need dedicated storage solutions to protect them from spoilage and contamination before they enter the manufacturing cycle. Storage usually refers to particular storage space. For example, having enough warehouse storage. Or clearing out a production facility for more floor space.  However, in this case, we are referring to the equipment and solutions that make storage manageable and easier. Such equipment includes solutions such as storage racks, pallet racks and shelving systems. These are just some of many storage options available to manufacturers. Advanced technology facilitates the management of heavy duty and high density tank and silo systems by automating the delivery system and linking it with the rest of the production line.

Storage

transportation

When transferring powders in an industrial setting, creating a dust-tight seal is crucial to maintain cleanliness and prevent contamination during the charging or discharging process.
<h2>Ensure dust-tight transfer and containment</h2>
The Hanningfield Uni-Cap is a flexible silicone rubber seal designed for dust-tight transfer or containment of powders. The Uni-Cap can be adapted to various sizes and configurations, making it compatible with multiple types of process equipment, including mills, tablet presses, and vessels. The caps are available in several sizes, ranging from 2.5 inches to 16 inches in diameter, and are made from translucent FDA-compliant silicone. The Uni-Cap+ variant is fully transparent, offering excellent process visibility, which is particularly beneficial for monitoring powder flow and container fill levels. Both versions can be easily retrofitted to any process and come with stainless steel mounting rings for secure installation. The silicone used is platinum-cured, compliant with FDA standard 177.2600, and is also USP Class VI, TSE/BSE-free, ADI-free, and phthalates-free. For traceability, the manufacturing batch ID can be embossed onto the caps. Hanningfield Process Systems manufactures these caps in Great Britain.

Silicone dust caps for dust-tight powder transfer

In the food processing industry, achieving consistent product shapes and high production rates while maintaining flexibility for different product types is crucial. Manufacturers face challenges in seamlessly transitioning between varied product forms and incorporating automated processes efficiently.
<h2>Adaptably form and cut various product types</h2>
The FS 525 forming and cutting system from Handtmann offers an all-in-one solution for forming diverse product shapes, supported by two distinct forming principles: hole plate forming for 3D products and rotary cutting for different cross-sections. This flexibility allows for efficient production of meat, dairy, vegetarian, vegan, dough-based products, and even confectionery and pet food. Its robust design facilitates rapid set-up and conversion between products, optimizing machine utilization and minimizing downtime. An optional co-extrusion feature enables the formation of filled products with calibres between 20 to 50 mm, providing further application versatility. High throughput is achieved with up to 150 portions per minute on a single lane, and automation compatibility ensures streamlined processing, from weighing to packaging.

Industrial forming and cutting system for diverse products

Cutting

Packaging

In pharmaceutical production, transferring sterile or toxic materials between different containment areas poses significant challenges. Contamination risks and maintaining sterile conditions are critical concerns that need to be addressed to ensure safety for both the operator and the product.
<h2>Enable secure bi-directional material transfer</h2>
The DPTE® Beta Containers by Getinge offer a reliable solution for transferring materials in and out of barrier systems without breaking containment. These containers are available in stainless steel or polyethylene and ensure safe, contamination-free transfers in life science applications. The system uses an Alpha part interacting with a Beta part, each fitted with a door, lock, and sealing function. These containers can be sterilized using autoclave, gamma irradiation, or H2O2 bio-decontamination methods, making them suitable for a wide range of sterilization processes. Optional racks and accessories enhance the versatility and usability of the containers, enabling secure loading and unloading. The containers are compatible with the Getinge DPTE® Alpha flange, ensuring a leak-tight and reliable transfer process.

Reusable containers for sterile and toxic material transfer

A loading system feeds your continuous or batch processing machine with the specified material or item in line with the flow of production. Loaders transfer the articles from one stage of preparation to the next with uniformity and accuracy.

Loading

Unloading

Manual

In sterile or hazardous environments, maintaining containment and preventing contamination during the transfer of materials is crucial. Situations such as cleanroom operations, filling lines, or isolator applications need a reliable method to ensure safety and sterility.
<h2>Ensure contamination-free transfer</h2>
The DPTE®-XS Alpha Port by Getinge is a robust solution designed for safe and leak-tight transfer in aseptic or toxic working areas. Featuring a manual 60° rotation to connect Alpha and Beta parts, this port ensures that openings and closures do not compromise sterility or containment. Its lip seals provide a validated, air-tight connection, establishing it as the industry standard for reliable and safe transfer processes. Widely applicable in processes such as liquid and component transfer, waste disposal, and environmental monitoring, the DPTE®-XS Alpha Port is validated to meet rigorous international regulations, thereby assuring quality and safety in diverse industrial applications.

Aseptic transfer port for secure bi-directional transfer

Handling bulk materials in industries like food, pharmaceuticals, and chemicals requires an effective system to unload big bags safely and efficiently. Challenges include dust containment, ensuring flowability of various powder types, and maintaining hygiene standards.
<h2>Safe and dust-tight unloading of big bags</h2>
The Gericke Big Bag Unloader BBU is designed to tackle these issues with its modular, flexible design. It allows for customization to meet specific needs and future adjustments. With options like vibrating tables for medium flowing powders and under massagers for poor flowing powders, it ensures efficient material handling. Safety features such as stretch units for outlet spout stretching and hoisting from different angles enhance operator safety. It also offers solutions for dust containment and hygienic execution, meeting high safety and hygiene standards. The system can integrate into various process lines, either discharging directly into hoppers or conveying systems.

Big bag unloader for industrial bulk materials

In processes where hygiene and efficiency are critical, the use of conventional flexible sleeves with hose clamps can create product retention zones, posing contamination and maintenance challenges.
<h2>Prevent contamination and ensure tight sealing</h2>
The BFM Fittings by Gericke offer a hygienic solution for connecting flexible sleeves to rigid tubing without creating product retention zones. Unlike traditional clamps, the BFM design ensures a perfectly waterproof and hygienic connection, eliminating dead zones that can harbor contaminants. Suitable for food grade applications, these fittings are made from Polyurethane, with other materials available upon request. They are easy to replace, requiring no tools and less than 40 seconds to fit. Available in diameters ranging from 100 to 650 mm, the BFM Fittings are designed to maintain tight seals even with very fine powders and withstand pressure shocks during dust explosions. This makes maintenance straightforward and reduces downtime, ensuring a clean and safe production environment across various industries including food and pharmaceuticals.

Hygienic flexible sleeves for food and pharmaceutical use

In lab environments dedicated to food, bio-pharmaceutical, and cosmetic research, maintaining impeccably clean and sterile glassware is essential. Traditional methods often fall short, requiring a more advanced system to handle specific cleaning and sterilization requirements efficiently.
<h2>Improves washing performance with steam</h2>
The FGW Lab Glassware Washer by Fedegari is designed to meet the stringent cleaning needs of various industrial labs. Leveraging the steam generation technology from the FOWS-series used in the pharmaceutical sector, this washer delivers superior cleaning by utilizing steam's emollient properties on greasy and sticky residues. Steam's ability to reach hard-to-access areas ensures thorough cleaning, while significantly reducing operational costs by minimizing detergent and water use. The FGW also features a conductivity meter to monitor water purity, enabling process termination upon reaching desired purity levels, further conserving resources. Continuous oversight of the cleaning process is maintained through dedicated probes checking air/water temperature and steam in the chamber. Additionally, an internal LED lamp provides visibility throughout the washing cycle, alerting users to any issues via color change signals.

Lab glassware washer for food and bio-pharmaceutical applications

In food processing environments, maintaining high sterility while handling various types of liquid products can pose significant challenges. From fruit purees to semi-concentrates with pieces in suspension, ensuring proper aseptic conditions and efficient filling is key to maintaining product integrity.
<h2>Ensures sterility and precision filling</h2>
The NEW double head aseptic filler from FBR ELPO, designed to fill bags ranging from 3 to 200 liters, stands out for its ability to handle a wide variety of liquids and semi-concentrates, including those with suspended pieces. Equipped with two mobile filling heads and a tilting system, it can also be coupled with an automatic palletizer for full drums. The product filling utilizes caps and spouts of 1" or 2", which can be sterilized with steam or special chemical agents as needed. The electric control panel with a touch screen interface offers on-screen controls ensuring precise filling. The filler achieves operational speeds of up to 12,000 kg/h, making it a reliable and efficient choice. FBR ELPO's contributions to sterility and performance ensure that this aseptic filler can meet rigorous processing standards in various industries.

Aseptic filler for liquids and semi-concentrates

If storing and transporting products easily is a problem for your industrial production, then you need palletizing solutions. A pallet is a flat structure, on which containers of the packaged products are stacked to consolidate the product and to make it easier for a forklift to lift the goods for warehousing and transportation. A palletizer is a machine that automates or simplifies the process of stacking product containers onto a pallet. The choice of an industrial palletizer depends on the type of product packaging such as bags, drums, or boxes, the level of automation required, and the in-feed to the palletizer. Palletizers find applications in all major industries including food, chemical, and pharmaceutical.

Palletizing

In various industrial and pharmaceutical settings, maintaining a controlled aseptic environment is crucial when transporting sensitive materials across different locations. This ensures that the integrity and sterility of the materials are preserved without contamination, particularly in operations requiring aseptic isolators.
<h2>Facilitates aseptic transfer with mobility</h2>
The Mobile Isolator by Fabtech is designed for scenarios where the work environment must be mobile or when materials need to be transferred between aseptic isolators. The Mobile Isolator is robustly constructed in SS 316L with laminar airflow ISO 5 Grade A classification to ensure high-level contamination control. It is equipped with wheels for easy movement and can be operated independently with optional battery packs. The isolator features customizable ergonomics to suit various operational needs. It comes in a standard configuration with one pass box (2 glove ports) and a main chamber (4 glove ports), including a glove integrity tester; multiple chamber configuration options are available. It also supports on-demand process equipment and online particle counter integration. H2O2 decontamination is optional for achieving an aseptic environment and maintaining process integrity. Room air intake and exhaust systems ensure a closed, controlled environment within the isolator. The system also features password protection for different authorization levels, supporting secure operation.

Mobile isolator for aseptic environment transfer

Decontamination

Industrial filtration equipment separates solid matter from liquid by using a filter medium. The filter allows only the fluid to pass through but retains the solid matter. The choice of filtration equipment depends on the particle size, the consistency of the mixture, and the nature of your product.

Filtration

In industries dealing with bulk powders or granules, transferring materials efficiently and safely without creating dust is crucial. Traditional methods can be labor-intensive and expose workers to potential hazards. An automated, hygienic, and dust-free solution is desired to maintain productivity and safety.
<h2>Ensure safe and dust-free material transfer</h2>
The FabLife Vacuum Transfer System (VTS) by Fabtech is designed for the efficient and safe transfer of powders and granules. It features integrated filters, WIP (wash-in-place) ports, and vibrators for effective material handling. The system uses vacuum to suck materials from the dispensing container and transfer them to the next vessel. It operates in a closed-loop, which prevents dust generation and contamination. The VTS is capable of handling diverse bulk densities and particle sizes, and it can be customized to meet specific requirements. Featuring programmable logic controller (PLC) integration and operation through a human-machine interface (HMI), the system ensures efficient and user-friendly performance. This equipment is especially suited for applications in the pharmaceutical, food processing, and chemical industries.

Vacuum transfer system for powders and granules

In the packaging industry, maintaining the integrity of products while ensuring efficient and versatile packaging options is a key challenge. The ability to create packages sealed on three sides from flexible wrapping material can streamline operations and improve product protection.
<h2>Achieve efficient three-sided sealing</h2>
The Gemini by Delfin is a horizontal flow pack packaging system designed for creating packages sealed on three sides using flexible wrapping materials. It features a reel positioned at the lower part, facilitating simple and quick format changes, and thus enhancing its flexibility for varying packaging needs. The system is driven by four Brushless motors, providing reliable and consistent performance. With a mechanical speed of up to 120 cycles per minute, it ensures a fast packaging process. The Gemini can handle a standard film width of 500 mm and is compliant with EC standards, ensuring it meets necessary regulatory requirements. Ideally suited for diverse packaging applications, it can be integrated seamlessly into automated production lines.

Flow pack packaging system for flexible wrapping material

When handling potent and hazardous powders in pharmaceutical or chemical plants, maintaining high containment during the packaging process is essential. Uncontrolled powder discharge can pose significant risks to worker safety and industrial hygiene standards, necessitating specialized equipment to manage these materials securely.
<h2>Ensure safe and contained powder packaging</h2>
The Pack-Off Station from De Dietrich is designed for the contained transfer of wet or dry powders into lined drums. This system uses continuous bag liners to maintain high containment levels, preventing exposure to toxic and explosive powders. The station supports both manual and automatic operation, with features such as automatic filtered bag purge and adjustable fill weight accuracy to within 5g. It can process drum sizes from 15 to 60 liters and includes options for integration with De Dietrich's Powder Pump and Filter/Dryer systems. The station is compliant with ATEX and FDA regulations, ensuring it meets stringent safety and hygiene standards required in pharmaceutical and chemical industries.

Powder conditioning station for high containment applications

Handling toxic powders during industrial processes requires a safe and contained transfer system to prevent contamination and ensure operator safety. Efficient and secure transfer methods are essential in environments where powder containment is critical.
<h2>Securely transfer powders with advanced containment</h2>
The Drum Dock Station by De Dietrich is designed for the safe and contained transfer of powders from drums into other processing systems. Utilizing DIT® Drum Iris Technology, this station allows operators to handle reactive or toxic powders with minimal exposure and contamination risks. The station is available in single and double chamber configurations, providing varying levels of containment, up to OEB 6. The body is constructed from high-grade materials such as AISI 304, AISI 316, and HASTELLOY C-22, ensuring durability and compatibility with different chemical processes. The integration with multiple powder transfer systems, including the De Dietrich Powder Pump, enhances its flexibility. Additionally, features like pneumatic lifters for drum inversion, customizable glove ports, and a double Push-Push H14 filtration unit for maintaining negative pressure during the transfer process make it suitable for high-containment applications in industries such as pharmaceuticals and fine chemicals.

Powder handling drum dock station

In the biodiesel production industry, one of the key challenges faced is ensuring the feedstock is adequately prepared for the transesterification process. This involves reducing both phosphatides and fatty acids to prevent inefficiencies downstream.
<h2>Efficiently prepares diverse feedstocks for transesterification</h2>
The biodiesel pretreatment system by Crown Iron Works is designed for continuous operation with a focus on efficiency and safety. Utilizing a process similar to edible oil refining, it reduces both phosphatides and fatty acids in the feedstock. This flexible design accommodates various biodiesel feedstocks, streamlining the pretreatment process. Byproducts from the pretreatment are comparable to those in edible oil production, allowing their sale in existing markets. Crown Iron Works' proven design ensures maximum reliability and product quality, which helps save on capital and operational expenses in the transesterification plant. Additionally, the system can be adapted for the production of edible oils based on market conditions.

Biodiesel pretreatment system

In large-scale food processing, efficiently storing and transferring materials between different processing stages is critical. Handling issues such as product bridging or maintaining sanitary conditions can be challenging, especially with heavy and continuous loads.
<h2>Transfer and store bulk materials seamlessly</h2>
The Horizontal Screw Loader from Cozzini is designed to store and transfer products efficiently in food processing operations. The loader features a 9-inch diameter heavy-duty stainless steel feedscrew auger, which ensures reliable and consistent transportation of bulk materials. An optional agitator is available to prevent product bridging, enhancing the flow of material. The unit has capacities ranging from 500 lbs. to 10,000 lbs. and is equipped with quick-release, watertight shaft seals for full washdown sanitation. The Horizontal Screw Loader is USDA accepted and CE approved, built in conformity with AMI sanitary equipment design principles, making it a robust solution for maintaining strict hygiene standards.

Horizontal screw loader for food processing

In modern pharmaceutical and biotech industries, ensuring the sterility of drug products during the filling process is paramount. Challenges such as contamination risks and the need for compliance with stringent regulatory standards require advanced solutions.
<h2>Enable aseptic filling with high precision</h2>
The Comecer SuperTrak PHARMA8™ is an advanced sterile filling system designed for aseptic environments. This system integrates asynchronous conveyance technology within Comecer's isolator to maintain Grade A air quality in operation, reducing particle generation due to minimal moving components. It supports the filling of vials, syringes, bags, cartridges, combination products, ampules, dry powder processing, and pills. The system's speed can reach up to 2.5 m/s with acceleration up to 30 m/s², providing high-speed sterile filling while ensuring product sterility and operator safety. It meets cGMP, FDA, CE, and UL regulatory requirements and is equipped with handling gloves and integrated hydrogen peroxide generators (VPHP) for optimal cleanliness. Supplier: Comecer.

High quality sterile filling system

In pharmaceutical manufacturing, ensuring sterility and precision in filling dry powders into devices is crucial. Challenges include preventing contamination, ensuring accurate dosage, and maintaining containment to meet safety standards.
<h2>Automate powder filling and capping under containment</h2>
The Dry Powder Filling Isolator by Comecer provides a fully automated solution for filling and capping dry powders in a controlled environment. Featuring a compact footprint, the system comprises four distinct chambers: a pre-chamber for introducing empty devices, a chamber for cap insertion, the main filling chamber, and a pre-chamber for outputting filled devices. The isolator achieves OEB4 containment levels, ensuring high safety standards. It operates with three distinct powder dosing heads for flexibility and precision in dosing. An integrated scale performs 100% weight checks, rejecting non-compliant products. The solution includes automated Wash-In-Place for the entire process chamber using spray guns, and controlled capping by robotic arms with grippers, making it highly reliable. Comecer ensures efficiency and compliance with stringent regulatory requirements.

Dry powder filling isolator for cgmp production

When looking for capping equipment, it is crucial to know first which type of capper your product requires. Do you want screw caps, twist-off caps, hand pumps, or push-pull caps on your bottle or container? If you require different cap types for format changeover times can be time-consuming. The bottle cap seals the top opening of a bottle to guard the product against leakage and spoilage and sterility and filling requirements depend on the nature of your product.

Capping

Industrial washing systems are used to clean and disinfect a variety of items in research and manufacturing facilities. Industrial washers use solvents and cleaning agents with mechanical action to remove deposits and residues from stainless steel machinery components, empty containers, and other soiled surfaces. The selection of an industrial or commercial washer depends on the type of items and surfaces to be cleaned, the type of deposits/residue that is typically present, whether drying is required after rinsing and the level of sterilization necessary. Manufacturers will have cleaning specifications and as a result, require washers to be engineered to meet these specs.

Washing

Managing radioactive solid waste requires containment solutions that can shield harmful radiation while ensuring easy handling and decontamination. Standard disposal methods often challenge operators with safety and contamination risks.
<h2>Shield harmful radiation safely and efficiently</h2>
The Comecer CR Series consists of shielded canisters for the safe and efficient disposal of radioactive solid waste. Constructed from AISI 304 stainless steel with a Scotch-BriteTM decontaminable finish, these canisters are designed for durability and easy decontamination. Each canister is shielded with 3 mm of lead in all directions, offering robust radiation protection. A unique feature is the helical screw mechanism for the lid, operated by a foot pedal, allowing for hands-free opening and closing. The series includes two models: the CR20-05 with a capacity of 20 liters, a weight of 30 kg, and dimensions of 280 mm x 500 mm (Ø x h); and the larger CR40-03 with a capacity of 40 liters, a weight of 25 kg, and dimensions of 380 mm x 515 mm (Ø x h). These canisters are ideal for use in nuclear medicine, radiopharmacy, and other settings where radioactive waste management is critical.

Shielded canisters for radioactive solid waste disposal

Rinsing

In pharmaceutical manufacturing, stringent standards for asepsis and containment are essential when processing intravenous (IV) bags. Traditional methods can involve significant human intervention, increasing the risk of contamination and errors.
<h2>Provides high-speed aseptic filling for Iv bags.</h2>
The automatic aseptic filling line for IV bags from Comecer is a high-speed, turnkey solution capable of processing various IV bag formats in both small and large batches. Using isolation technology from start to finish, it guarantees asepsis and containment, minimizing human intervention. The system includes in-line integrity testing and can handle bags ranging from 50 ml to 1 liter without requiring format part changes. It manages up to 2300 pieces per hour with either peristaltic or volumetric integration and incorporates LAF isolation technology along with a built-in VPHP decontamination system. Primarily used in the pharmaceutical industry, this filling line ensures complete separation between the process and the operator.

Automatic aseptic filling line for Iv bags

Packaging processes in industries like food and pharmaceuticals often require precise and automated solutions to handle different types of containers such as glass jars, metal or plastic cans. The challenge is to ensure accuracy and performance while maintaining flexibility in automation levels.
<h2>Customizable packaging lines for diverse container types</h2>
The comprehensive packaging lines from Collischan are designed to work in tandem with their dosing scales or counting machines, providing tailored automation and performance based on customer specifications. Each line can handle a variety of containers, using unscramblers, rotary tables, or manual feeding for container input. Transport belts are available in numerous lengths and widths and can be configured for single or multiple lanes. The filling stations ensure secure placement of weighed or counted products into containers. For sealing, the containers can be closed semi-automatically or fully automatically, and can be collected on a rotary table or transferred to subsequent machines. Optional integration of blow-off devices, labelers, sealing units, and other equipment into the packaging line is also available. Each line is tested, validated by customer personnel for accuracy, performance, and build quality before delivery. Collischan provides support for on-site commissioning as well.

Complete packaging lines for various containers

In pharmaceutical manufacturing, transferring powder ingredients while ensuring containment and sterility can be a challenge. This is especially true for manufacturers who need to transfer ingredients between process steps or different facilities frequently.
<h2>Facilitates safe and sterile powder transfers</h2>
The ChargePoint® single use valve passive (SUP) is designed for pharmaceutical manufacturers who require an economic and contained powder transfer system. Functioning as the passive mating half of the ChargePoint Split Butterfly Valve system, it ensures high containment and sterility performance, reducing the need for cleaning, maintenance, and validation. Manufactured with FDA and USP Class VI compliant plastic, the SUP is lightweight and cost-effective for single-use purposes. It is produced in an ISO6 cleanroom environment and can be gamma sterilized for aseptic processing. Available as part of a complete package with the ChargeBag® PE-S, it offers seamless integration with optional tri-clamp connections or direct welding to ChargeBags. ChargePoint Technology provides an accessory GMP cover to secure the passive and connected container, ensuring product integrity during storage or transit.

Single use valves for powder transfer

Industrial disinfection equipment use antimicrobial agents to destroy microorganisms found on machines, floors, walls, and other surfaces. In industry, disinfection of machinery and the production area is important to prevent product contamination which may lead to spoilage and health hazards for workers and the consumer. The choice of industrial cleaning equipment depends on the level of disinfection needed, the sanitizing agent, the size of the area or objects to be treated, and the suitable method of treatment such as sterilization, pasteurization, exposure to ultraviolet light, or chemical fogging.

Disinfection

In pharmaceutical and other regulated industries, handling and transferring bulk powders efficiently and safely is crucial. Challenges like space optimization, contamination prevention, and compliance with industry standards require specialised containers designed to meet these specific needs.
<h2>Streamline bulk powder handling and transfer</h2>
The PuroVaso® plastic containers, by Chargepoint Technology, are devised to address the inefficiencies associated with traditional plastic charge bottles and stainless steel vessels. These containers range from 1 litre to 50 litres, offering the largest selection of plastic container sizes, which ensures that you can select the right volume for your batch size. The square bottle geometry maximizes facility space and reduces equipment stack-up heights, effectively lowering storage and transportation costs. Intelligent design features include moulded side profiles for easy clamping with the PuroGrab™. The containers come with 4” and 6” tri-clamp neck fittings, allowing compatibility with a variety of valve options. Available in different PE materials, they cater to various needs such as anti-static properties and UV protection. The rotational moulding process guarantees a crevice-free internal surface, and batch numbers are moulded in for full traceability. The materials used are suitable for gamma irradiation sterilization, ensuring compliance with sterilization standards. These containers are both reusable and recyclable, making them a sustainable choice.

Plastic containers for bulk powder transfer

In pharmaceutical manufacturing, handling and transferring biopharmaceutical powders can present challenges related to cross-contamination and the need for extensive cleaning and validation processes.
<h2>Ensure containment and sterility with single-use bags</h2>
The ChargeBag® PE-S is a high-integrity, single-use powder transfer bag designed by ChargePoint Technology. Made from HiPure™ ULP7, a pharma-ready LLDPE film, this bag offers robust mechanical strength and anti-static properties. Manufactured in an ISO6 cleanroom environment, each bag is 100% pressure decay tested and gamma sterilized for aseptic conditions. The ChargeBag® PE-S minimizes the risk of cross-contamination and eliminates cleaning and validation expenses. It features a non-migrating anti-static additive for effective powder recovery and transparent characteristics for easy visual inspection. Additionally, its HDPE reinforced handle and hygienic tri-clamp ferrule ensure safe and convenient connectivity to existing systems, including ChargePoint’s split butterfly valves.

Single use powder handling bags for pharmaceutical ingredients

Ensuring the cleanliness and sterility of transfer valves is crucial in aseptic manufacturing. Contaminants and residues pose significant risks, requiring thorough and effective cleaning processes to maintain safety and compliance.
<h2>Enhances cleaning efficacy and reduces contamination risk</h2>
The Active Cleaning Cap from Chargepoint Technology is a specialized accessory designed for efficient in-place cleaning and decontamination of the Active half of Split Butterfly Valve (SBV) systems. This device maximizes the surface area exposed to cleaning media by a unique sealing methodology on its outer perimeter, eliminating the need for typical seat/disc components that hinder cleaning efficacy. Various configurations cater to WIP (Wash In Place), SIP (Steam/Sterilize In Place), and CIP (Clean In Place) processes, adapting to different installation orientations and specific process needs like draining and venting. By employing a liquid and gas-tight seal via an o-ring, the cap allows in-place opening and closing of the valve within a sealed environment, ensuring effective cleaning without operator exposure. Suitable for use in the pharmaceutical, chemical, and food industries, the cap supports applications requiring stringent sterility and safety standards. The accessory is pressure-rated and available in sizes up to 200mm, with special features like a hygienic tri-clamp connection and optional integrated spray ball for enhanced cleaning performance.

Transfer valve cleaning for sterility assurance

Pilot

Scaling up microbiological synthesis processes from the laboratory to small-scale production requires precise and reliable equipment. This is vital for applications in pharmaceutical production, veterinary chemicals, and biotechnology research centers.
<h2>Facilitates efficient scale-up and small-scale production</h2>
The BRS pilot fermentors and bioreactors by Brs Biotechnology Equipment serve as a crucial link between laboratory-scale experiments and larger production scales. These units, with volumes ranging from 5 to 80 liters, are designed for small-scale pilot production of agricultural and veterinary chemicals, pharmaceutical production, and diverse biotech processes. Their platform-mounted, open-frame modular construction allows easy access for maintenance and operations. Central connections for steam, water, and air minimize start-up time and effort. Advanced models feature automatic air flow metering, optical density sensors, and remote control systems via SCADA. The fermentors support a wide range of processes involving enzymes, bacteria, fungi, algae, and various cell cultures. Compliant with GMP and FDA standards, they are optimized for medium and process optimization in research settings.

Pilot fermentors for biotech processes

Aerators are devices used for mixing air (oxygen transfer) with a liquid such as water or oil to form a homogeneous product. Selecting an industrial aeration system involves choosing a suitable mixing head and considering the desired input and output flows, temperature, level of aeration, properties of the liquid phase, and the degree of automation and pressure control. Aerators are used in the food industry for the production of fat-based center masses and crèmes and in the chemical industry for wastewater treatment. When it comes to water treatment, surface aerators are most commonly used.

Aeration

The fermentation process stimulates enzymatic activity in organic substrates to transform their chemical composition. Fermentation is aided by storying the biomaterials in anaerobic environments, allowing the microorganisms to decompose their nutrient structures. The process is integral to some of the most popular products throughout time such as wine, beer, cheese, and kimchi. But besides the food sector, fermentation is also an important stage in the industrial manufacturing of chemicals, pharmaceuticals, and biofuels.

Fermentation

Formulation technologies are an integral process in many industries such as pharma and food. Chemical mixtures require strict handling to combine the separate ingredients into the homogenized recipe that makes your final product. Formulation technology stores, mixes and subjects the elements to a range processing parameters according to your specifications to develop the base material. The resulting formulas are then weighed, formed, packaged, or sent for further formulation.

Formulation

Complex processes call for continuous tracking and monitoring systems that help you to keep the manufacturing operation under control. The technology analyzes the components in the production phase for divergence in behavior or changes in conditions. Based on advanced software applications, monitoring platforms make sure that your products satisfy the quality criteria while they are being developed.

Monitoring

After completing a brew day, ensuring thorough cleaning of tanks is critical. Maintaining the required temperature of cleaning solutions presents a challenge, as conventional systems often fail to sustain temperatures, reducing effectiveness.
<h2>Maintains temperature with in-line heating</h2>
The Mobile CIP Carts by Brewmation offer a robust solution for brewery cleaning needs, equipped with innovative in-line heating. This feature ensures the caustic solution's temperature remains consistent, preventing loss of cleaning efficiency. The carts also come with a separate sanitizer line to avoid cross-contamination and directional valves for easy recirculation and transfer. Available in standard sizes (20, 40, 75, and 100 gallons) with custom sizes available upon request, these carts are ideal for various brewery tank capacities. The 6000W or 15000W heating element is GFCI protected, as is the digital temperature controller that provides precise control. Variable speed pumps adapt to different sizes, further enhancing flexibility and convenience. The entire assembly is UL/cUL listed, ensuring compliance with safety standards.

Mobile Cip carts for brewery cleaning

For industries requiring efficient solid-liquid separation in hazardous or sensitive environments, traditional methods often pose contamination risks and inefficiencies. Ensuring hermetic processing and high-purity output while managing toxic or sensitive materials remains a significant challenge.
<h2>Perform filtration and vacuum drying efficiently</h2>
The Agitated Nutsche Filter Dryer by Bachiller excels in solid-liquid separation via pressure filtration and vacuum drying. Designed according to cGMP and EHEDG standards, it's suitable for pharmaceuticals, fine chemicals, and food industries. It operates within a hermetic system to prevent contamination, ensuring high-purity outputs. Capable of batch-wise operations, it supports multiple processes like reaction, filtration, and drying within a single unit. Features include a filtering surface ranging from 0.07 m² to 15 m² and operational capacity from 19L to 15,000L. It operates up to 3 bar(g) pressure and 200º C, catering to both heating and cooling needs. Options are available for CIP/SIP systems, different internal finishes, and advanced sealing mechanisms.

Agitated nutsche filter dryer for solid-liquid separation

Industrial cooling equipment varies according to the consistency and temperature conversion demands the material you are handling, but the process typically involves heat exchange treatment as your products are conveyed through a cooling chamber equipped with extraction fans or circulating water. Temperature control is a crucial aspect of your commercial production and cooling systems are applied to a range of industries.

Cooling

Industrial drying machines are designed to remove moisture from your product. But the drying process must cater to variations in the state of matter and molecular structure of the input material. Industrial dryer technology exploits the modes of heat transfer (convection, conduction, radiation, evaporative cooling) to control the moisture content.

Drying

<span style="font-weight: 400">The heating process is a step of raising the temperature of food, pharma, cosmetics, and many other types of products. You may employ different heating solutions for this process, depending on the type of product you intend to manufacture. Selecting the appropriate heater machine for your product is quite important since various products require different ranges of temperatures and different ways of heat transfer using exchangers. Industrial heating equipment varies in two ways - the type of material it can process and the reaction you want to achieve.</span>

Heating

Handling bulk materials often involves transferring contents between containers or bins and other processing equipment. This can produce dust, posing a contamination risk and requiring additional cleaning steps.
<h2>Ensure dust-free transfers with minimal manual effort</h2>
The AZO Docking Collar is designed to enable dust-free docking of containers and bins in the bulk-materials processing industry. Its patented shape and pliable material create a secure, dust-free connection between containers and downstream inlet pieces such as dosing screws and fall pipes, without using mechanically or pneumatically moved parts. This simple construction not only ensures easy handling but also facilitates fast mounting and dismounting, boosting overall operational efficiency. Made from food-grade rubber, it meets high hygiene standards, making it suitable for applications in industries that require stringent cleanliness. The construction allows straightforward cleaning, reducing downtime and maintenance efforts.

Dust-free docking collar for containers and bins

In industrial settings with undervacuum homogenizers, maintaining cleanliness is crucial for preventing contamination and ensuring product quality. Traditional cleaning methods can be inefficient and time-consuming, especially when dealing with complex machinery that requires thorough internal cleaning.
<h2>Facilitates efficient internal cleaning</h2>
The Cleaning system CIP 'Cleaning in Place' by Axomatic (Marchesini Group) is a mobile, external cleaning unit specifically designed to connect to undervacuum homogenizers. This system feeds internal cleaning spray balls with pressurized water, ensuring comprehensive internal cleaning without disassembly of the homogenizer parts. By integrating this system, facilities can achieve more efficient and effective cleaning processes, reducing downtime and minimizing the risk of contamination. The system's mobility allows it to be conveniently moved and connected to various homogenizers, offering flexibility in multi-machine environments.

Cleaning system Cip for internal equipment maintenance

When working in environments that require strict containment, such as pharmaceutical manufacturing or laboratories, traditional open handling systems can expose workers and materials to contamination risks. These challenges necessitate the use of a reliable containment solution for critical processes.
<h2>Ensure containment flexibility and safety</h2>
The Flexible Isolator from Austar is designed for effective containment in controlled environments. It offers a cost-effective solution compared to rigid isolators, featuring flexible materials that can accommodate varying operational spaces. The Flexible Isolator provides high transparency for better visual monitoring and thorough cleaning. It is compatible with a range of equipment, making it ideal for diverse applications, including dispensing, filtration, sampling, and powder conveying. With its higher economic efficiency and ability to dock with other devices, it is particularly suitable for operations that need both containment and flexibility.

Flexible isolator for aseptic containment

Dispensing

Industrial sampling equipment are systems that allow manufacturers to test (in other words to take a sample of) the products they are manufacturing. This process is generally implemented as a means of quality control but it can also be used as a mean to ensure that production processes adhere to certain regulatory standards. Quality control in your manufacturing process starts with precision sampling techniques. Automated systems deliver consistent samples at a pre-set rate for accurate testing and probing. Sampling technology uses a calibration system involving a series of sensors to extract the material at high levels of reliability.

Sampling

In the pharmaceutical industry, producing non-sterile active pharmaceutical ingredients (APIs) often involves challenges like dust containment, precise material handling, and operator safety during processing and packaging. Effective systems are required to manage these aspects, especially for highly toxic or flammable materials.
<h2>Ensure safe and efficient Api production</h2>
The non-sterile API production line by Austar provides a comprehensive solution for manufacturing powder and solid pharmaceutical formulations. The closed feeding system in the chemical synthesis workshop ensures a dust-free process, reducing labor intensity and minimizing environmental impact from vaporized organic solvents. Depending on the material properties and feed amounts, different systems are available, including Closed Unloading Stations for FIBCs, Dust-free Feeding Stations for small bags, and Containment Reactor Feeding Systems for highly toxic and flammable materials. The BPC and Intermediate Quantitative & Packaging System handles crushing, sieving, metal detection, and automatic measurement in a closed environment, enhancing weight accuracy and reducing manual labor. For highly-active and highly-toxic materials, the combined filtration dryer and isolator provide an OEB3-OEB5 compliant closed packaging system, ensuring operator safety and higher product yield.

Non-sterile Api production line for powder and solid formulations

Ensuring sterile liquid transfer during pharmaceutical manufacturing is crucial for maintaining product safety. The challenge lies in transferring fluids across sterile boundaries in environments like isolators or RABS without contamination.
<h2>Maintain sterility during liquid transfers</h2>
The AT-Port™ System by Aseptic Technologies is an alpha-beta aseptic liquid connection system designed to enable safe liquid transfer between different containment classification areas while ensuring sterility. Its core components include the Connector Port, and the Disposable Connector Devices, AT-Connector™ and AT-Connect™. The AT-Connector™ is suited for large volumes and can be used for up to five opening-closing operations, ensuring reliable, repeated use. The AT-Connect™ is ideal for precise, low volume transfers, maintaining sterility with seamless integration into aseptic filling lines. Made with silicone and thermoplastic elastomer (C-Flex®) tubing, it ensures all product contact points remain sterile. Distributed by Sartorius Stedim under the name Gammasart Aseptic Transfer Device (ATD™), this system is widely used in cGMP pharmaceutical formulation, fill & finish, and other critical liquid product handling applications.

Aseptic liquid transfer connection system

Transfer

Packaging small cheese products, especially those with varying shapes and sizes, can be challenging. These tasks require a system capable of handling diverse packaging materials and ensuring quick format changes without excessive downtime or labor-intensive processes.
<h2>Wrap small cheese products automatically</h2>
The MultiSAN from ALPMA Alpenland Maschinenbau GmbH is an automatic wrapping solution designed for small cheese products of various shapes and sizes. It offers maximum flexibility with packaging materials and allows tool-free changes of format parts and product-touching parts. Achieving up to 100 packages per minute, the MultiSAN can handle diameters between 60-160mm, lengths between 60-140mm, widths between 60-120mm, and heights between 15-60mm. The system's optimal accessibility simplifies cleaning and maintenance, further enhancing its operational efficiency.

Automatic packaging for small cheese products

In research and process development, determining the right membrane filtration method—whether microfiltration, ultrafiltration, nanofiltration, or reverse osmosis—is crucial. Challenges include scalability, controlling viscosities, and maintaining optimal temperatures for reliable separation of components.
<h2>Flexible filtration with multiple membrane options</h2>
The Alfa Laval PilotUnit Multi is a sophisticated system designed for versatile membrane filtration testing. Capable of operating in both batch and semi-batch modes, this system supports microfiltration, ultrafiltration, nanofiltration, and reverse osmosis. Its fully integrated design sits on a wheeled stainless steel structure, featuring a 40-liter tank, pump, heat exchanger, and control system. The pump system’s capability to handle various viscosities and the high-temperature and pH tolerance of its pHt™ membranes offer a flexible solution for different applications. Additionally, options like online monitoring, data logging, and expandable membrane area (3–15 m²) enhance its performance for scaling processes or small-scale production. The Alfa Laval PilotUnit Multi allows for efficient product concentration with minimal media use, and its compact design ensures ease of operation and maintenance.

Multipurpose membrane filtration system for pilot testing

Concentration

Entry level

When conducting synthetic reactions in a controlled environment, maintaining precise temperature and vacuum conditions is essential. Researchers face challenges in achieving uniform material mixing and consistent reaction parameters.
<h2>Facilitates controlled synthetic reactions</h2>
The Ai R-series single glass reactor system by Across International is designed specifically for synthetic reaction processes, allowing for precise temperature and vacuum control. The system features adjustable stirring speeds and a constant pressure feeding funnel to ensure uniform material addition. It includes a built-in condenser for material recovery at a controlled rate. The reactor utilizes solvent-resistant PTFE on all sealing components, enhancing durability. Hand-made from food grade high borosilicate glass, the reactor is corrosion-resistant and operates across a wide temperature range, from -120°C to 200°C. The single jacketed design supports both 2L and 5L vessel options for customizable use. Additional features include a large condenser cooling surface, a reinforced PTFE stirrer, and digital speed and temperature displays for easy monitoring.

2l single jacketed glass reactor system

In high-demand confectionery production, efficiently managing limited space while maintaining high output is a key challenge. Adaptable equipment that fits within constrained floor-to-ceiling heights without compromising performance is essential.
<h2>Streamline chocolate moulding with adaptable configurations</h2>
The Jensen Moulding Line from Aasted is a compact and flexible chocolate moulding line designed to fit production facilities with low floor-to-ceiling heights. It operates with minimal noise and features a user-friendly HMI. The modular design allows for pre-constructed, high-quality components tailored to specific production needs. The line can operate as two standalone lines for simple applications or a single coherent line for advanced moulding. The new cross conveyor feature enables producing while cleaning or conducting maintenance, thus reducing changeover time. Suitable for a variety of products including solid moulds, inclusions, and FrozenCone® shell products, the Jensen line supports production capacities ranging from 200 to 2,200 kg/hour. Additionally, it offers increased output capacity with new 700x18" moulds, achieving up to 2,100 kg/h for tablets and 1,800 kg/h for pralines.

Flexible chocolate moulding line for limited space production

Maintenance

<span style="font-weight: 400">The molding process is often included in bakery products. Utilizing molding equipment guarantees a uniform shape, weight, and size. The molding machine first gently flattens the dough mix by going through a sheeter, where a series of rollers press the thin piece of dough. The sheet is then cut into the specified shape and, depending on your final product, may be rolled by using a curling chain. After the molding, other ingredients may be added before the products are conveyed for baking or freezing.</span>

Moulding

In the confectionery and bakery industries, achieving uniform aeration in masses and precise depositing of fat fillings is crucial. This process often faces challenges such as maintaining consistent texture and preventing contamination, requiring specialized equipment for optimal results.
<h2>Achieve precise aeration and depositing</h2>
The ESA depositor from Aasted is an advanced solution designed for the deposition of aerated masses and fat fillings. The depositor's closed construction of the hopper and depositor head ensures contamination-free production. It features highly accurate and gentle movements, which create the finest aerated mass with consistent texture. The ESA is adaptable to any production line and includes optional features like built-in lifting of moulds or oscillating hopper movement during depositing. This technology is suited for medium to large scale production and is designed for easy cleaning and maintenance, ensuring minimal downtime and high productivity.

Depositor for aerated masses and fat fillings

Depositing equipment is a very common production line process in the food industry. Whether you want to make muffins or jellies or garnish and decorate cakes, all of this is impossible without the depositing step. Depositing is a form of extrusion used primarily to produce pieces of dough that will be further processed to create several food products. The dough is passed through a depositing machine and poured in equal parts from holes in a die plate with nozzles or a conveyor belt. But that’s not all. Depositors are also used to fill, layer, or cover your food items with other ingredients before proceeding to the next step of the production process which is usually packaging.

Depositing

When sampling or transferring hazardous substances and sensitive bulk goods, a dust-tight seal is vital to prevent contamination. Stringent protection requirements can make this an expensive and lengthy process.
<h2>Connect process units and single-use blown film containers with secure, disposable clamping system</h2>
Flecotric containment tri-clamps are available in various sizes that match standard process unit connection diameters from 2’’ to 12’’ and are often used to integrate the Rommelag Flex Flecozip connection with process units.
The transfer containers range in size from a few millilitres to 100 litre capacity and are simply disposed of after use.
The tri-clamp system connects and seals with the help of two locking rings and is supplied with a regular TC gasket to allow use with other standard docking systems.

Flexible containment solutions

Which flexible containment solutions technology do you need?