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During crime scene investigations in any movie, you’ve probably seen forensic scientists collecting evidence and biological samples in small containers. Here, these are the vials, used to store medicines, especially in liquid form, or laboratory samples. Often made of glass or plastic, vials can be labeled as single-dose vials or sterilized and reused more than once. They are also available with various closure systems depending on the material and storage requirements.

Which vials equipment do you need?

Hygienic Cartoning Machine For Pharma and Health Products

When packing single or multiple vials, ampoules or devices int...

Aseptic liquid filler for vials

Compact modular aseptic filler of vials with parenteral medicines and freeze-dried products.

Flexible automatic inspection machine for ampoules, vials, cartridges

If you are looking to improve the efficiency of y...

Small automatic inspector for ampoules, vials, or cartridges

Inspect small batch production of ampoules, vials, or cartr...

Semi-automatic inspection machine for ampoules, vials or cartridges

If you need to increase the efficiency of your manu...

Visual and HVLD inspection for ampoules, vials and cartridges

Do you need to improve the efficiency and capability of yo...

Pharmaceutical rotary labeling machine for vials

Small, cylindrical-shaped glass bottles or vials are mainly used for vacc...

Benchtop piston filling equipment for vials in trays

Vials are difficult to fill individually through manual methods due ...

Compact laboratory freeze dryer

Particularly suitable for research centers requiring greater freeze drying capacity. Some of...

Custom engineered freeze dryer

For either bulk format or liquid in vials, ampoules or syringes, the Lyomega units are design...

Dry heat depyrogenation oven

Specially designed for the drying and sterilization of glass containers, vials or ampoules, and...

GMP laboratory freeze dryer

Freeze dryer designed for aseptic and small-scale production of high-value products.

Pharmaceutical bottles inspection machine

For the visual inspection of small to medium batch-sizes of vials, ampoules or b...

Labeling machines for pharmaceutical bottles

Labels for ampoules, vials and bottles are typically applied at the end of th...

High-speed aseptic injectable vial filling machine

Fill up to 24,000 vials per hour with pharmaceutical powders or liquid...

Sterile filling line for injectables

Sterile filling of liquids and powders for the pharmaceutical and cosmetic industries ...

Start-up sterile filling line for injectables

For smaller-scale production of vials and syringes for the injectables marke...

Table top sterile filling line for injectables

Where a compact solution is required for filling vials for the injectables ...

Horizontal cartoner for pharma and cosmetics

Most pharmaceutical and cosmetics products are packed in cardboard cartons fo...

Online fraction collector for offline bioprocess analysis

Many bioprocesses require offl...

Packaging machine for syringes in trays

Pre-dosed syringes are rapidly becoming the method ...

Rotary vial washing machine

When washing vial, ampoules, or cartridges for pharmaceutical pr...

Vial sterilization tunnel

Sterilization of vials, ampoules and syringes before filling is a ...

Vial filling machine

The volume filling of vials, cartridges and syringes is a vital part of ...

Industrial vial capping machine

The high capacity production of pharmaceuticals delivered in...

External vial washing machine

Exterior washing solutions for vials often suffer from high wa...

Aseptic automatic vial filling machine

Current and future developments in pharmaceuticals i...

Aseptic automatic vial washing machine

The production of the latest high value pharmaceuticals often requires aseptic handl...

Nested syringe filling machine

Increasingly, pre-sterilized Ready To Use (RTU) nested vials,...

Labeling machine for BFS containers

The pharmaceutical sector is unquestionably one of the major industries that rely on th...

Entry-level filler for large-volume parenterals

Large volume parenterals are unit-dose containers that are larger than 100...

Automatic vial tray loader

In modern pharmaceutical production, end-line processes are often...

Laboratory liquid viewer for colored glass bottles

In the pharmaceutical industry, an inspection to detect any particulat...

Semi-automatic vial crimper

In a small production line, crimping vials manually can cause fatigue to the operator due to mul...

Pilot freeze dryer for scale up

Designed for biological, pharmaceutical and food products formulation and "scale up" work.

GMP freeze dryer

Designed to perform clinical trials, pilot, and small scale or large scale industrial drying processes, in ac...

Superheated water shower autoclave

Specially designed for sterilizing large batches of parenteral solutions.

Sterility test isolators

Designed to avoid this risk and protect the product from both the process and externally generated f...

Compact horizontal laminar flow bench

HEPA filtered horizontal laminar airflow (cross-flow) creates an optimized free space...

Microbiological safety cabinet class II

This handy device offers the most advanced features in product-operator protection ...

Biosafety cabinet class II for cytotoxic medicines

For the manipulation of hazardous substances utilized during the prepa...

Positive pressure isolator

Ideal for products which have no biological risk but require high sterile conditions.

Biological safety cabinet class III

Specially designed for the handling of microbiological agents, when working with indige...

Versatile checkweigher

This Versatile checkweigher is equipped with a highly versatile strain gauge load cell. It is also sui...

Small bottle checkweigher

Any small-diameter bottle, containing prescription medication or cosmetic applications, can be pro...

Flexible automatic inspection machine for syringes

Manufacture of pre-filled syringes requires the highest quality inspec...

High capacity cartoner for pharmaceutical applications

Many pharmaceutical products are p...

Pharmaceutical and cosmetic industry products cartoner

A large number of cosmetic and pha...

High-capacity horizontal cartoner for pharma and cosmetics appliances

Cartoners take ca...

Continuous pack cartoner

High volume automatic cartoning is vital for large scale production ...

GMP chamber washer

The thorough cleaning of small product contact parts has always been chall...

Aseptic vial cap sealing machine

Aseptic production methods are at the heart of the latest d...

Sterile compounding system

Hospitals and compounding centres have traditionally used manual ...

Cleaning and sterilization systems

An increasingly vital part of high quality pharmaceutica...

R&D bottle cap press

Small scale producers of liquids contained in bottles with press-on lids and caps need capping machines ...

Pharmaceutical data management software

A typical pharmaceutical production handles numerous work flow activities like mana...
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Stories about Vials

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When selecting production equipment for a production plant, it is important to talk to someone with experience in your field. Our industry experts have experience with various industrial applications. We’d love to help you!
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A vial for every application

Vials really do have millions of uses based on the material and application. Glass vials have been used for hundreds of years to store liquid pharmaceutical products. But glass is not always the same. For instance, The United States Pharmacopeia (USP) classifies glass into borosilicate glass as Type I and soda-lime-silica glass as Type II and III, with the difference being that  Type II has a special treatment to increase hydrolytic resistance.

Borosilicate glass contains at least 5% of boric oxide and is used for injectables with acid, neutral and alkaline pH. Amber-colored vials, created by adding iron to the glass, protect the substance from UV light and are suitable for light-sensitive samples.

 

Plastic vials, made of polypropylene or polyethylene, are widely used in cosmetics and law enforcement agencies. Compared to glass vials, they have lower chances of leaching and are much easier to handle. Plastic vials have excellent resistance to bases, alcohol, and acids. Special vials are also made for specific applications like cryogenic or liquid scintillation. Cryogenic vials are made of special polypropylene material to withstand extremely low temperatures. Scintillation vials are mostly glass vials used in liquid scintillation counting; this process is used to measure the substance’s radioactive activity.

Single-dose vials or multi-dose vials?

In medical applications, single-dose and multiple-dose vials are available. Single-dose vials are intended for one-time use and do not contain anti-microbial preservatives. The contents must be used within an hour after opening and any remaining contents must be discarded. These vials must be appropriately disposed of afterward. Multi-dose vials contain more than one dose of medication and contain anti-microbial preservatives to prevent the growth of bacteria after opening. It must be used for a single patient as much as possible to avoid cross-contamination and must not be used after the beyond-use date indicated on the label.

Coat your vials to improve chemical resistance

Glass delamination occurs in the inner surface of the container when exposed to chemicals due to chemical reactions and leaching of elements from the glass. As a result, glass flakes appear mixed with the chemical solution. If you think about it, this is a serious quality issue. Leaching of elements from the glass, such as sodium affects the pH level of the solution over time and may even lose the product’s efficacy.

As a solution, glass vials are treated by the vapor phase deposition silanization (or siliconization) method. This process involves applying a silicon solution to the surface as a protective layer to minimize the interaction between the vial and the substance. This method provides a uniform glass coating that improves the chemical resistance and gives a low adsorption characteristic preventing chemicals from sticking to the surface.

Aseptic vial filling equipment to ensure the safety of pharmaceutical products

Aseptic filling is fundamental in pharmaceutical industries to guarantee the quality and safety of its products from contaminants that may cause a reaction to the product leading to health risks when used. Exposure to contaminants also deteriorates the product quickly. The filling process starts with a vial washer before it goes to depyrogenation tunnels to remove pyrogens such as endotoxins and exotoxins. After sterilizing, vials are filled and stoppered by vial filling equipment. Then, they go to the capping and crimping machine for sealing.

Vial labeling and serialization equipment for product traceability

Serialization is a process used for product traceability operations. Information such as production-expiration date, lot number, and serial numbers are stored in a data center. By assigning a unique code to a drug packaging, counterfeiting of drug products can be prevented. Serialization is usually integrated with the labeling process of the vials. A high-resolution printer writes the labels with all the information required and then a code-reading camera is used during the verification process for readability.

Processing steps involved in vials making

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