Ampoules Making Equipment
Find innovative production technology for making ampoules and connect directly with world-leading specialists
After being used to contain the blood of martyrs after death or to store the anointing oil of French monarchs, today ampoules are the first choice in packaging injectables. You create ampoules by melting the glass tube into the desired shape and seal them at the neck by melting the top of the glass tube. The only way for you to extract the contents from an ampoule is by breaking the glass at its breaking point, making it perfect for single dose applications only.
Which ampoules equipment do you need?
Hygienic Cartoning Machine For Pharma and Health Products
When packing single or multiple vials, ampoules or devices into…
Automatic washing machine for ampoules
Automatic washing machine designed for cleaning ampoules and achieving a maximum outp…
Manual ampoule filler
When filling ampoules is essential to avoid wetting the inside walls of the container, as it may affect …
Benchtop ampoule opening and closing equipment
The procedure for opening or closing ampoules requires the handling of gas a…
Visual and HVLD inspection for ampoules, vials and cartridges
Do you need to improve the efficiency and capability of you…
Semi-automatic inspection machine for ampoules, vials or cartridges
If you need to increase the efficiency of your manua…
Small automatic inspector for ampoules, vials, or cartridges
Inspect small batch production of ampoules, vials, or cartri…
Flexible automatic inspection machine for ampoules, vials, cartridges
If you are looking to improve the efficiency of yo…
Ampoule filling machine
Filling ampoules or vials with parenteral fluids are an essential matter for which you need to conside…
Laboratory liquid viewer
Impurities like hair, fibers or glass, sourced from the environment, equipment or packaging can conta…
Laboratory liquid viewer for transparent glass bottles
In the pharmaceutical industry, an inspection of liquids in vials o…
External vial washing machine
Exterior washing solutions for vials often suffer from high water consumption and low throughpu…
Vial sterilization tunnel
Sterilization of vials, ampoules and syringes before filling is a vital step in the production of r…
Rotary vial washing machine
When washing vial, ampoules, or cartridges for pharmaceutical production there is often a trade-o…
Packaging machine for syringes in trays
Pre-dosed syringes are rapidly becoming the method of choice for the delivery of inj…
High-capacity horizontal cartoner for pharma and cosmetics appliances
Cartoners take carton blanks which are formed and …
Automatic cartoner for applications in pharma and cosmetics
For high capacity production of cosmetics and pharmaceuticals…
Horizontal cartoner for pharma and cosmetics
Most pharmaceutical and cosmetics products are packed in cardboard cartons for…
High capacity cartoner for pharmaceutical applications
Many pharmaceutical products are packed in protective and decorativ…
Vertical cartoner for pharmaceutical applications
Many pharmaceutical and cosmetic products are sold in protective and dec…
Labeling machines for pharmaceutical bottles
Labels for ampoules, vials and bottles are typically applied at the end of the…
Pharmaceutical bottles inspection machine
For the visual inspection of small to medium batch-sizes of vials, ampoules or bo…
Dry heat depyrogenation oven
Specially designed for the drying and sterilization of glass containers, vials or ampoules, and …
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Sign upCustom engineered freeze dryer
For either bulk format or liquid in vials, ampoules or syringes, the Lyomega units are designe…
Pharmaceutical data management software
A typical pharmaceutical production handles numerous work flow activities like manag…
Horizontal cartoner for pharmaceutical applications
Automatic cartoning for cosmetic or pharmaceutical products is a requi…
Cleaning and sterilization systems
An increasingly vital part of high quality pharmaceutical production is a dedicated Clean…
Continuous pack cartoner
High volume automatic cartoning is vital for large scale production of cosmetic or pharmaceutical pro…
Pharmaceutical and cosmetic industry products cartoner
A large number of cosmetic and pharmaceutical products are packed i…
Flexible automatic inspection machine for syringes
Manufacture of pre-filled syringes requires the highest quality inspect…
Table top sterile filling line for injectables
Where a compact solution is required for filling vials for the injectables m…
Start-up sterile filling line for injectables
For smaller-scale production of vials and syringes for the injectables market…
Sterile filling line for injectables
Sterile filling of liquids and powders for the pharmaceutical and cosmetic industries r…
Biological safety cabinet class III
Specially designed for the handling of microbiological agents, when working with indigen…
Positive pressure isolator
Ideal for products which have no biological risk but require high sterile conditions.
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Contact usTypes of ampoules: shapes that fit the standards
Based on the shape of their head from ISO standards, you can count three types of ampoules: straight-stem (form B), funnel type (form C), and sealed (form D). ISO 9187-1:2010 specifies materials, dimensions, capacities, performance and packaging requirements for three forms of glass ampoule for injectable pharmaceutical products.
Straight-stem ampoules and funnel-types have open ends for the customers to wash and sterilize before filling and sealing. Sealed ampoules instead have dome-shaped closed ends, which means that ampoules are supplied already sterilized. This is done prior to the ampoule going through their respective filling and sealing machines. Customers have to open them with a sharp flame before filling them and then reseal them.
Ampoules also have different break systems. One point cut (OPC) refers to a small cut on the constriction of the ampoule and is paired with a colored dot mark for the position of the breaking cut. Color break ring (CBR) refers to an enamel ring applied around the constriction as a marker for the breaking cut. Scoring (SCO) refers to surface markings of the glass around the constriction part.
Plastic ampoules as a new possibility
Plastic ampoules are getting more popular in pharmaceutical companies. They are less costly to manufacture, easier to transport and store as they have better breaking resistance. Actually, they do not require tearing or cutting the top portion, because you can simply snap off the neck to open. Their manufacturing process offers more accurate dosages and prevents overfill of products, making it more efficient compared to glass.
Check the quality through ampoule inspection machine
Quality control for pharmaceutical products is a critical process. It requires multiple visual inspections to ensure that the products are not contaminated, and the packaging is intact and clean. You can opt for a fully automatic or semi-automatic inspection machine equipped with image sensors and magnifying cameras to check the correct fill level, detect contaminating particles, glass defects and container leakage.
Other options available for inspection machines include detecting product color using illumination and sensors, and container closure integrity using multiple cameras that check the position of the cap.
Color coding for identification
Have you ever noticed that ampoules have colored rings around their neck?
The colored rings are used as a code to identify the substance inside the ampoule. This makes it easier to sort them for the purposes of storage, labeling, and packaging. These rings are machine-readable for easier identification and printed by rotating discs using heavy-metal-free inks for safety reasons.
Difference between ampoules and vials
Ampoules are meant for single-use or single-dose applications since they are sealed at the neck with heat and you have to crack them open to extract the contents. With vials it is another story. You only need to remove the caps or pierce the rubber stopper with a syringe. As for the content inside, ampoules store unstable chemical compounds and highly volatile elements while vials are for storing stable compounds.
Specialised machinery for ampoule production
When it comes to the full production of making ampoules, specialised machines and manufacturing processes need to be followed. For example, all ampoule production lines and machinery should be made from high quality stainless steel. This is because the contents simply cannot be contaminated. The production process also includes the use of an ampoule filler, for liquid filling as well as Labeling machines and heating stations for sealing the glass.