Let's make effervescent tablets
The fizz of effervescent tablets is commonly associated with a vitamin C boost. But the soluble pill is an excellent drug delivery method for pediatric and geriatric patients. Sometimes referred to as carbon tablets, manufacturing effervescent tablets binds biocarbonate and citric acid that produce the smooth hiss as they dissolve in liquid.
Which effervescent tablets equipment do you need?
Continuous roller compactor for dry granulation of pharmaceuticals
Strip packaging machine for effervescent tablets
Premium vacuum conveyor
Powder tester
R&D electronic counter for capsules and tablets
High-sensitivity metal detection system
Sorption dehumidifier with air-chilled condenser
Small portable dehumidifier
Sorption dehumidifier for large temperature differences
Sorption dehumidifier for deep drying
Dehumidifier for difficult wet airflows
Sorption dehumidifier for overpressured rooms
Heat recycling sorption dehumidifier
Industrial desiccant dehumidifier
Large scale desiccant dehumidifier
Customizable dehumidifier
Small feeder with flexible wall hopper
Entry-level high-shear mixer for drug formulation
High-shear mixer
Granulation line of mixer and fluid bed dryer
Rotary tablet press
Single and double layer tablet press
Single layer tablet press
Automatic tablet coater for lab scale
High Speed Tablet Press
High Speed Double-Sided Tablet Press
Dust-tight metal detector for tablets
Entry-level X-ray inspection system
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Select your effervescent tablets process
Tell us about your production challenge
Manufacturing effervescent tablets with a mix of lubricants reduces scumming
Water-soluble lubricants such as sodium benzoate have an added benefit in acting as glidants when manufacturing effervescent tablets. The anti-adherent properties of the organic salt add plasticity to the final product.
However, the inclusion of other lubricants like magnesium stearate and polyethylene glycol in negligible amounts reduces scumming in the final solution.
Limit humidity to 1.0% weight during wet granulation
Moisture levels are restrained to between 18°C and 23°C, with 10% relative humidity during the manufacturing process.
This presents an added challenge when wet granulation is performed. During this stage, water is kept to a maximum of 1.0% weight by weight of the mixture. Granules are then immediately conveyed to an oven dryer.
Apply drying agents in tube packaging
Avoid polymer blister materials or tubes for packaging that let in moisture and air. The compaction of effervescent tablets traps air bubbles. But if the tablets are exposed to water or oxygen, these will trigger the effervescent reaction ahead of use.
Blister packaging and aluminum foil protect the tablets from the surrounding environment following manufacturing. In the case of tubes, drying agents or silica gel prevents the penetration of humidity and air.
