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The fizz of effervescent tablets is commonly associated with a vitamin C boost. But the soluble pill is an excellent drug delivery method for pediatric and geriatric patients. Sometimes referred to as carbon tablets, manufacturing effervescent tablets binds biocarbonate and citric acid that produce the smooth hiss as they dissolve in liquid.

Which effervescent tablets equipment do you need?

Continuous roller compactor for dry granulation of pharmaceuticals

When making tablets, pharmaceutical manufacturers ne...

Strip packaging machine for effervescent tablets

Pack your effervescent tablets with extreme precision and care at a speed...

Premium vacuum conveyor

When you have a need to tailor make your conveyor and still have the high requirement on hygiene, e.g...

Powder tester

When you want to predict powder behavior in future and existing installations, possible measures to be taken or ...

R&D electronic counter for capsules and tablets

This machine has been designed to offer an ever-precise and reliable count...

High-sensitivity metal detection system

Highly efficient metal detector with enhanced quality control and reporting capabil...

Sorption dehumidifier with air-chilled condenser

It is not always possible to duct out the wet air from a dehumidifier ser...

Small portable dehumidifier

Water damaged areas require dehumidification to limit the damage and prepare the area for restor...

Sorption dehumidifier for large temperature differences

Small, humid areas can be difficult to dehumidify in humid ambien...

Sorption dehumidifier for deep drying

Humid ambient conditions such as those in tropical climates make dehumidification mor...

Dehumidifier for difficult wet airflows

Sealed rooms can be challenging to dehumidify with ordinary dehumidifiers. The wet ...

Sorption dehumidifier for overpressured rooms

Small humid spaces, used for processing or storage, often need a simple dehu...

Heat recycling sorption dehumidifier

Facilities that handle large amounts of water can become very humid. High humidity may...

Industrial desiccant dehumidifier

Dehumidification of medium sized manufacturing and processing facilities can be a dauntin...

Large scale desiccant dehumidifier

Moisture sensitive processing and storage facilities need low humidity environments to s...

Customizable dehumidifier

Dehumidification needs can vary significantly from one project to another. Dehumidifiers with a fi...

Small feeder with flexible wall hopper

In many laboratory applications and production processes, smaller quantities of powd...

Entry-level high-shear mixer for drug formulation

For pilot and lab-scale pharmaceutical ...

High-shear mixer

For the efficient mixing of larger batches of pharmaceutical compounds and hi...

Granulation line of mixer and fluid bed dryer

A complete granulation line allows for the m...

Rotary tablet press

For pharmaceutical tablet producers looking to reduce waste, costs and  i...

Single and double layer tablet press

High performance tablet presses that are capable of pr...

Single layer tablet press

High performance tablet presses for the modern production environm...

Automatic tablet coater for lab scale

The ability to coat tablets in an even and controlled...

High Speed Tablet Press

High speed pharmaceutical tablet presses convert powder to tablets. The operations should be quick an...

High Speed Double-Sided Tablet Press

To achieve as much as double the output of single-sided tablet press, the upper and lo...

Dust-tight metal detector for tablets

For FDA-compliant production of tablets, the elimination of airborne dust containing ...

Entry-level X-ray inspection system

Without compromising on performance, if you need an entry level x-ray inspection system...

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Manufacturing effervescent tablets with a mix of lubricants reduces scumming

Water-soluble lubricants such as sodium benzoate have an added benefit in acting as glidants when manufacturing effervescent tablets. The anti-adherent properties of the organic salt add plasticity to the final product.

However, the inclusion of other lubricants like magnesium stearate and polyethylene glycol in negligible amounts reduces scumming in the final solution.

Limit humidity to 1.0% weight during wet granulation

Moisture levels are restrained to between 18°C and 23°C, with 10% relative humidity during the manufacturing process.

This presents an added challenge when wet granulation is performed. During this stage, water is kept to a maximum of 1.0% weight by weight of the mixture. Granules are then immediately conveyed to an oven dryer.

Apply drying agents in tube packaging

Avoid polymer blister materials or tubes for packaging that let in moisture and air. The compaction of effervescent tablets traps air bubbles. But if the tablets are exposed to water or oxygen, these will trigger the effervescent reaction ahead of use.

Blister packaging and aluminum foil protect the tablets from the surrounding environment following manufacturing. In the case of tubes, drying agents or silica gel prevents the penetration of humidity and air.

Processing steps involved in effervescent-tablets making

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