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The fizz of effervescent tablets is commonly associated with a vitamin C boost. But the soluble pill is an excellent drug delivery method for pediatric and geriatric patients. Sometimes referred to as carbon tablets, manufacturing effervescent tablets binds biocarbonate and citric acid that produce the smooth hiss as they dissolve in liquid.
Which effervescent tablets equipment do you need?
Continuous roller compactor for dry granulation of pharmaceuticals
When making tablets, pharmaceutical manufacturers nee…
Strip packaging machine for effervescent tablets
Pack your effervescent tablets with extreme precision and care at a speed …
Premium vacuum conveyor
When you have a need to tailor make your conveyor and still have the high requirement on hygiene, e.g.…
Powder tester
When you want to predict powder behavior in future and existing installations, possible measures to be taken or f…
R&D electronic counter for capsules and tablets
This machine has been designed to offer an ever-precise and reliable count …
High-sensitivity metal detection system
Highly efficient metal detector with enhanced quality control and reporting capabili…
Sorption dehumidifier with air-chilled condenser
It is not always possible to duct out the wet air from a dehumidifier serv…
Small portable dehumidifier
Water damaged areas require dehumidification to limit the damage and prepare the area for restora…
Sorption dehumidifier for large temperature differences
Small, humid areas can be difficult to dehumidify in humid ambient…
Sorption dehumidifier for deep drying
Humid ambient conditions such as those in tropical climates make dehumidification more…
Dehumidifier for difficult wet airflows
Sealed rooms can be challenging to dehumidify with ordinary dehumidifiers. The wet a…
Sorption dehumidifier for overpressured rooms
Small humid spaces, used for processing or storage, often need a simple dehum…
Heat recycling sorption dehumidifier
Facilities that handle large amounts of water can become very humid. High humidity may …
Industrial desiccant dehumidifier
Dehumidification of medium sized manufacturing and processing facilities can be a daunting…
Large scale desiccant dehumidifier
Moisture sensitive processing and storage facilities need low humidity environments to sa…
Customizable dehumidifier
Dehumidification needs can vary significantly from one project to another. Dehumidifiers with a fix…
Small feeder with flexible wall hopper
In many laboratory applications and production processes, smaller quantities of powde…
Entry-level high-shear mixer for drug formulation
For pilot and lab-scale pharmaceutical formulations, a high-shear granul…
High-shear mixer
For the efficient mixing of larger batches of pharmaceutical compounds and high-shear mixer provides the optim…
Granulation line of mixer and fluid bed dryer
A complete granulation line allows for the mixing and granulation of pharmace…
Rotary tablet press
For pharmaceutical tablet producers looking to reduce waste, costs and increase production volume, a high…
Single and double layer tablet press
High performance tablet presses that are capable of producing both single and double-la…
Single layer tablet press
High performance tablet presses for the modern production environment need to be fast, accurate and…
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Sign upAutomatic tablet coater for lab scale
The ability to coat tablets in an even and controlled way is an important stage in the…
High Speed Tablet Press
High speed pharmaceutical tablet presses convert powder to tablets. The operations should be quick and…
High Speed Double-Sided Tablet Press
To achieve as much as double the output of single-sided tablet press, the upper and low…
Dust-tight metal detector for tablets
For FDA-compliant production of tablets, the elimination of airborne dust containing a…
Entry-level X-ray inspection system
Without compromising on performance, if you need an entry level x-ray inspection system …
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Contact usManufacturing effervescent tablets with a mix of lubricants reduces scumming
Water-soluble lubricants such as sodium benzoate have an added benefit in acting as glidants when manufacturing effervescent tablets. The anti-adherent properties of the organic salt add plasticity to the final product.
However, the inclusion of other lubricants like magnesium stearate and polyethylene glycol in negligible amounts reduces scumming in the final solution.
Limit humidity to 1.0% weight during wet granulation
Moisture levels are restrained to between 18°C and 23°C, with 10% relative humidity during the manufacturing process.
This presents an added challenge when wet granulation is performed. During this stage, water is kept to a maximum of 1.0% weight by weight of the mixture. Granules are then immediately conveyed to an oven dryer.
Apply drying agents in tube packaging
Avoid polymer blister materials or tubes for packaging that let in moisture and air. The compaction of effervescent tablets traps air bubbles. But if the tablets are exposed to water or oxygen, these will trigger the effervescent reaction ahead of use.
Blister packaging and aluminum foil protect the tablets from the surrounding environment following manufacturing. In the case of tubes, drying agents or silica gel prevents the penetration of humidity and air.