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Cell Culture Equipment

Find innovative production technology for making cell cultures and connect directly with world-leading specialists.

Cells cultures making equipment

Cell culture has been, over a little more than 100 years, an important method of research in laboratories. But medicine developments aside, we wonder if even the most positive of idealists could have also believed that cell cultures and tissue culture would possibly change the way – and what – we eat. From the lab to the dining table, there’s cell culture equipment to make even the unimaginable possible.

Which cell cultures equipment do you need?

High-frequency vibratory mixer

High-frequency vibratory mixer

Mixing liquid products by stirring method generates heat from friction and shear forces. This …

Automated bubble traps for chromatography

Automated bubble traps for chromatography

Radial flow chromatography processes require special attention and the right use …

Pre-packed and pre-validated chromatography columns

Pre-packed and pre-validated chromatography columns

In chromatography, you must always take into account the apparatus tha…

Lab-scale radial chromatography columns for virus validation

Lab-scale radial chromatography columns for virus validation

In the food industry, as an example, during lab-testing and …

Complete bioreactor system

Complete bioreactor system

An autoclavable bioreactor establishes special conditions for a variety of applications, for examp…

Optical Dissolved Oxygen Sensors

Optical Dissolved Oxygen Sensors

Sufficient oxygen is critical to the success of processes like cell culture and fermentation…

Bioprocess control software

Bioprocess control software

Managing a large number of bioprocesses individually without automation is time-consuming, and th…

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Bioreactor software

Bioreactor software

Comprehensive upstream data acquisition and management are essential in the bioprocessing industry. That’…

Single use bioreactor

Single use bioreactor

Single use, micro-bioreactors could be a good solution for replication processes, especially when they e…

Laboratory test tube filling machine

Laboratory test tube filling machine

Test tube filling needs to be accurate and efficient. Moreover, large laboratories test…

Fast printer for petri dishes

Fast printer for petri dishes

Adding a rotary edge printing facility to a petri dish filling system can be complex and expens…

Industrial petri dish filling machine

Industrial petri dish filling machine

High throughput petri dish filling machines are traditionally slow and require a large…

Fully Automated On-Line Sampling for Bioprocesses

Fully Automated On-Line Sampling for Bioprocesses

Accurate sampling is a critical tool in the design and improvement of a …

Fluid sensor technology for flow rate measurement

Fluid sensor technology for flow rate measurement

For many bioprocesses, precise measurement of media flow rates is vital …

Accessory feed pump for various applications

Accessory feed pump for various applications

In many biopharmaceutical or chemical development processes, lab work can be g…

Fluid sample-taking module for high cell density cultures

Fluid sample-taking module for high cell density cultures

Automatic sampling of reactor vessels requires careful fluid ma…

Distributor of samples to different devices

Distributor of samples to different devices

The ability to expand your automatic sampling solution provides increased flexi…

Sampling probe suitable for fermenter samples

Sampling probe suitable for fermenter samples

Accurate, sterile sample collection is vital across a range of biopharmaceuti…

Sampling probe for bioreactor samples

Sampling probe for bioreactor samples

In biopharmaceutical and chemical industries, sampling is vital to develop, maintain, …

Online fraction collector for offline bioprocess analysis

Online fraction collector for offline bioprocess analysis

Many bioprocesses require offline analysis of samples to monito…

Online sampling system for larger scale bioprocesses

Online sampling system for larger scale bioprocesses

Accurate sampling is vital for improving a wide variety of industrial…

Automatic sampling system for bioprocess monitoring

Automatic sampling system for bioprocess monitoring

An accurate, automated sampling of cultures is a key requirement in th…

Entry-level automated online sampling system

Entry-level automated online sampling system

An accurate and sterile sampling of cultures is vital throughout the biopharma…

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Pilot high pressure homogenizer

Pilot high pressure homogenizer

For maximum value, a high-pressure homogenizer that’s suitable for both laboratory and pilot…

High pressure air powered laboratory homogenizer

High pressure air powered laboratory homogenizer

Offering lab-scale to small pharmaceutical production scale output for in …

High pressure electric laboratory homogenizer

High pressure electric laboratory homogenizer

It’s vital that small units for experimentation can scale up with 100% accur…

High pressure industrial homogenizer

High pressure industrial homogenizer

For any industrial pharmaceutical process that relies on high pressure homogenization i…

High pressure pilot homogenizer

High pressure pilot homogenizer

Biotech and pharmaceutical development programs often require a mixing method that achieves b…

24 fully controlled bioreactors in a microtiter format

24 fully controlled bioreactors in a microtiter format

When undertaking a screening study, process development or optimisa…

Compact H2O2 disinfection system

Compact H2O2 disinfection system

Dry fogging provides safe, effective microbiological cleaning of critical areas in biotech, …

Purification screening kit for large biomolecules

Purification screening kit for large biomolecules

To purify a specific large biomolecule, for example IgM or a virus or vi…

Plasmid process pack for your pDNA purification process

Plasmid process pack for your pDNA purification process

When developing a pDNA purification process for eventual transfer …

Short bed monolithic columns for analytics

Short bed monolithic columns for analytics

Samples taken at various process steps need to be analysed quickly and accurate …

Disposable monolithic columns

Disposable monolithic columns

Chromatographic monolithic columns for working with large proteins, viruses, VLPs and pDNA requ…

Automated cell culture clarification system

Automated cell culture clarification system

Efficient harvest from the bioreactor is essential to any successful cell cultu…

Stories about Cell cultures

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Shakers, incubators, bioreactors – cell culture technology for your production

Cell culture manufacturing is largely used in the production of vaccines, treatments for cancer, and therapeutic proteins and antibodies. There are two sources where to obtain the cell material: through a cell stock, thawing the frozen cells and including them in the culture, and through the isolation of the cells of a donor tissue culture.

Before starting the culture technique, producers carry on cell seeding and observation. Cell seeding guarantees the right cell density, and observation defines if the cells are viable and not contaminated by foreign objects.

Shake flasks are usually the tool in these initial stages. If everything is correct, then you can place the flasks in a CO2 incubator. In it, the concentration of oxygen is lower compared to a non-controlled environment, so the cells can start culturing.

Some biotechnology producers may prefer to use an integrated incubator shaker instead of a flask and a separate incubator, to simplify the process in one place. In this case, you need to define which incubator shaker design fits best to your needs. In other cases, a centrifuge is used to allow the cells to spin down.

Apart from these options, it’s also possible to use a bioreactor as your cell culture equipment. It will help further control, in real-time, the biology of the cells, as well as to fulfill criteria related to quality and efficacy. The most common type that producers use is the stirred-tank bioreactor (STR), which can be easily adjusted for large scale production.

Culture conditions: preparing the environment for your cell lines

Choosing equipment is important. But, to promote cell growth, you need more than cell culture technology; you also need to provide an environment with good conditions for it to work. Researchers use cell lines to conduct different experiments because they can evaluate how a set of cells with the same characteristics respond when submitted to varied conditions and reagents.

When creating these lines, one essential part of the process is to set the culture media formulation that will help cell types to grow. Basic culture medium composition includes glucose, amino acids (the most prominent one being L-glutamine), vitamins, proteins, antibiotics, and inorganic salts. Other components, however, vary according to the outcome expected from those cell lines. The insect cells culture, for instance, benefit from TC-100, while many mammalian cells are supported by RPMI 1640.

Set the optimal conditions for your stem cells culture

Stem cell culture is a valuable asset for research. These cells are particularly interesting due to their nature, as what makes them unique is exactly their ability to differentiate themselves into any cell and self-renew. Nonetheless, it’s precisely because of this that culturing stem cells require extra care and attention in order to provide the right environment for their growth. Stem cells can easily differentiate if the optimal conditions are not reached, but they can also stop responding to growth stimuli, going through the phenomenon of cellular senescence.

Processing steps involved in cell-cultures making

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