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Cell culture has been, over a little more than 100 years, an important method of research in laboratories. But medicine developments aside, we wonder if even the most positive of idealists could have also believed that cell cultures and tissue culture would possibly change the way – and what – we eat. From the lab to the dining table, there’s cell culture equipment to make even the unimaginable possible.

Which cell cultures equipment do you need?

High-frequency vibratory mixer

Mixing liquid products by stirring method generates heat from friction and shear forces. This...

Acoustic cell retention system

Using high frequency resonant ultrasonic waves to separate cells instead of a physical mesh o...

Autoclavable glass bioreactor

Especially designed for cell culture applications and research applications such as process op...

Autoclavable stainless steel bioreactor

For cell culture and microbial culture applications.

Photobioreactor for plant growth

SSL (Solid state lamps) plant light has unique and useful characteristics for plant growth ...

Lab scale Bioreactor controller

Success with bioprocesses is all about controlling the environmental conditions controls so ...

Small-scale bioreactor controller

When you are working with small bioreactors, starting from 50 ml volumes, you need a good...

Scalable bioreactor controller

When you are up-scaling bioprocesses, starting at the lab and going all the way to the pilot ...

Dissolved Oxygen sensor

The vast majority of all biotechnological processes are aerobic, where a microorganism or cell respon...

Steam-in-place bioreactor systems

Scaling-up from a laboratory scale to pilot plant and small scale production can be simpl...

Micro-Flask

During the initial stages of scale-up, researchers often have limited data available with which they must decide o...

Mini bioreactors

When a screening study takes place, optimizing media process and working with microbial and cell cultures is ...

pH Sensor

pH is one of the most important parameters of cell-culture and fermentation processing in the biotech industry. New ...

Resonance Acoustic Mixer

Utilized when applying low-frequency and high-intensity acoustic energy to agitate microbial culture...

Single-use bioreactor Appliflex

A single-use bioreactor is a bioreactor with a disposable bag instead of a culture vessel, c...

Single-use bioreactor CellReady 3L

A single-use bioreactor is quite simply a bioreactor with disposable vessel for culture ...

Single use bioreactor Hyclone

A single-use bioreactor is a bioreactor with a disposable vessel for culture of cells, instead...

Saturated steam GMP laboratory autoclave

For processing a wide range of products: solid, porous and liquids in a laboratory...

Compact horizontal laminar flow bench

HEPA filtered horizontal laminar airflow (cross-flow) creates an optimized free space...

Microbiological safety cabinet class II

This handy device offers the most advanced features in product-operator protection ...

Biosafety cabinet class II for cytotoxic medicines

For the manipulation of hazardous substances utilized during the prepa...

Positive pressure isolator

Ideal for products which have no biological risk but require high sterile conditions.

Biological safety cabinet class III

Specially designed for the handling of microbiological agents, when working with indige...

3D disposable bags for bioprocesses

Manufacturers in the bioprocessing industries are increasingly turning to single-use so...

Disposable tank liners

Manufacturers in the bioprocessing industries are increasingly turning to single use solutions for the...

Disposable manifold bags for bioprocesses

Manufacturers in the bioprocessing industries are increasingly turning to dispos...

Normal flow filtration sets for bioprocesses

Bio-processors require reliable, high quality, easy to maintain, filtration e...

Disposable mixer bags for bioprocesses

Bioprocessors must use ingredients of known high quality and consistency.  Inconsist...

Disposable pillow bags for bioprocesses

Manufacturers in the bioprocessing industries are increasingly turning to single us...

Biocompatible tubing for peristaltic pumps

Sensitive bioprocess applications requires equipment that will not interfere wi...

Y sets tubing for bioprocesses

Manufactueres in the bioprocessing industries are increasingly turning to single use solution...

Disposable tubing for manifolds in bioprocesses

Manufacturers in the bioprocessing industries are increasingly turning to ...

Automated single use tangential flow filtration system

Tangential Flow Filtration is an essential to the biopharmaceutica...

Semi-automated tangential flow filtration system

Tangential Flow Filtration is an essential to the biopharmaceutical proce...

Semi-automated normal flow filtration system

Normal Flow Filtration is frequently used the biopharmaceutical processing in...

Bag holder and weighing platform for bioprocesses

Single use bags for biopharmaceutical process containment and liquid st...

Lab scale tangential flow filtration system

Tangential Flow Filtration is an essential to the biopharmaceutical processing...

Lab scale normal flow filtration system

Normal Flow Filtration is frequently used the biopharmaceutical processing industry...

Automated dispensing system for bioprocesses

Biopharmaceutical manufacturers require precisely known liquid quantities for...

Single-use pressure sensor

Biopharmaceutical manufacturers are increasingly making use of Single-use pressure sensors to enh...

Single-use conductivity sensor

Biopharmaceutical manufacturers are increasingly making use of single-use conductivity sensor...

Single-use temperature sensor

Biopharmaceutical manufacturers are increasingly making use of single-use temperature sensors ...

Automated cell culture clarification system

Efficient harvest from the bioreactor is essential to any successful cell cult...

Disposable monolithic columns

Chromatographic monolithic columns for working with large proteins, viruses, VLPs and pDNA req...

Short bed monolithic columns for analytics

Samples taken at various process steps need to be analysed quickly and accurate...

Plasmid process pack for your pDNA purification process

When developing a pDNA purification process for eventual transfer...

Purification screening kit for large biomolecules

To purify a specific large biomolecule, for example IgM or a virus or v...

Compact H2O2 disinfection system

Dry fogging provides safe, effective microbiological cleaning of critical areas in biotech,...

24 fully controlled bioreactors in a microtiter format

When undertaking a screening study, process development or optimis...

High pressure pilot homogenizer

Biotech and pharmaceutical development programs often requir...

High pressure industrial homogenizer

For any industrial pharmaceutical process that relies ...

High pressure electric laboratory homogenizer

It’s vital that small units for experimenta...

High pressure air powered laboratory homogenizer

Offering lab-scale to small pharmaceutica...

Pilot high pressure homogenizer

For maximum value, a high-pressure homogenizer that’s suita...

Entry-level automated online sampling system

An accurate and sterile sampling of cultures ...

Automatic sampling system for bioprocess monitoring

An accurate, automated sampling of cu...

Online sampling system for larger scale bioprocesses

Accurate sampling is vital for impro...

Online fraction collector for offline bioprocess analysis

Many bioprocesses require offl...

Sampling probe for bioreactor samples

In biopharmaceutical and chemical industries, samplin...

Sampling probe suitable for fermenter samples

Accurate, sterile sample collection is vital...

Distributor of samples to different devices

The ability to expand your automatic sampling ...

Fluid sample-taking module for high cell density cultures

Automatic sampling of reactor ...

Accessory feed pump for various applications

In many biopharmaceutical or chemical develop...

Fluid sensor technology for flow rate measurement

For many bioprocesses, precise measurem...

Fully Automated On-Line Sampling for Bioprocesses

Accurate sampling is a critical tool in the design and improvement of a...

Industrial petri dish filling machine

High throughput petri dish filling machines are traditionally slow and require a larg...

Fast printer for petri dishes

Adding a rotary edge printing facility to a petri dish filling system can be complex and expen...

Laboratory test tube filling machine

Test tube filling needs to be accurate and efficient. Moreover, large laboratories tes...

Single use bioreactor

Single use, micro-bioreactors could be a good solution for replication processes, especially when they ...

Bioreactor software

Comprehensive upstream data acquisition and management are essential in the bioprocessing industry. That...

Bioprocess control software

Managing a large number of bioprocesses individually without automation is time-consuming, and t...

Optical Dissolved Oxygen Sensors

Sufficient oxygen is critical to the success of processes like cell culture and fermentatio...

Complete bioreactor system

An autoclavable bioreactor establishes special conditions for a variety of applications, for exam...

Lab-scale radial chromatography columns for virus validation

In the food industry, as an example, during lab-testing and...

Pre-packed and pre-validated chromatography columns

In chromatography, you must always take into account the apparatus th...

Automated bubble traps for chromatography

Radial flow chromatography processes require special attention and the right use...
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Stories about Cell cultures

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Tell us about your production challenge

When selecting production equipment for a production plant, it is important to talk to someone with experience in your field. Our industry experts have experience with various industrial applications. We’d love to help you!
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Shakers, incubators, bioreactors – cell culture technology for your production

Cell culture manufacturing is largely used in the production of vaccines, treatments for cancer, and therapeutic proteins and antibodies. There are two sources where to obtain the cell material: through a cell stock, thawing the frozen cells and including them in the culture, and through the isolation of the cells of a donor tissue culture.

Before starting the culture technique, producers carry on cell seeding and observation. Cell seeding guarantees the right cell density, and observation defines if the cells are viable and not contaminated by foreign objects.

Shake flasks are usually the tool in these initial stages. If everything is correct, then you can place the flasks in a CO2 incubator. In it, the concentration of oxygen is lower compared to a non-controlled environment, so the cells can start culturing.

Some biotechnology producers may prefer to use an integrated incubator shaker instead of a flask and a separate incubator, to simplify the process in one place. In this case, you need to define which incubator shaker design fits best to your needs. In other cases, a centrifuge is used to allow the cells to spin down.

Apart from these options, it’s also possible to use a bioreactor as your cell culture equipment. It will help further control, in real-time, the biology of the cells, as well as to fulfill criteria related to quality and efficacy. The most common type that producers use is the stirred-tank bioreactor (STR), which can be easily adjusted for large scale production.

Culture conditions: preparing the environment for your cell lines

Choosing equipment is important. But, to promote cell growth, you need more than cell culture technology; you also need to provide an environment with good conditions for it to work. Researchers use cell lines to conduct different experiments because they can evaluate how a set of cells with the same characteristics respond when submitted to varied conditions and reagents.

When creating these lines, one essential part of the process is to set the culture media formulation that will help cell types to grow. Basic culture medium composition includes glucose, amino acids (the most prominent one being L-glutamine), vitamins, proteins, antibiotics, and inorganic salts. Other components, however, vary according to the outcome expected from those cell lines. The insect cells culture, for instance, benefit from TC-100, while many mammalian cells are supported by RPMI 1640.

Set the optimal conditions for your stem cells culture

Stem cell culture is a valuable asset for research. These cells are particularly interesting due to their nature, as what makes them unique is exactly their ability to differentiate themselves into any cell and self-renew. Nonetheless, it’s precisely because of this that culturing stem cells require extra care and attention in order to provide the right environment for their growth. Stem cells can easily differentiate if the optimal conditions are not reached, but they can also stop responding to growth stimuli, going through the phenomenon of cellular senescence.

Processing steps involved in cell-cultures making

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