Cell Culture Equipment
Find innovative production technology for making cell cultures and connect directly with world-leading specialists.
Cell culture has been, over a little more than 100 years, an important method of research in laboratories. But medicine developments aside, we wonder if even the most positive of idealists could have also believed that cell cultures and tissue culture would possibly change the way – and what – we eat. From the lab to the dining table, there’s cell culture equipment to make even the unimaginable possible.
Which cell cultures technology do you need?
High-frequency vibratory mixer
Mixing liquid products by stirring method generates heat from friction and shear forces. This …
Automated bubble traps for chromatography
Radial flow chromatography processes require special attention and the right use …
Pre-packed and pre-validated chromatography columns
In chromatography, you must always take into account the apparatus tha…
Lab-scale radial chromatography columns for virus validation
In the food industry, as an example, during lab-testing and …
Laboratory test tube filling machine
Test tube filling needs to be accurate and efficient. Moreover, large laboratories test…
Fast printer for petri dishes
Adding a rotary edge printing facility to a petri dish filling system can be complex and expens…
Industrial petri dish filling machine
High throughput petri dish filling machines are traditionally slow and require a large…
Fully Automated On-Line Sampling for Bioprocesses
Accurate sampling is a critical tool in the design and improvement of a …
Fluid sensor technology for flow rate measurement
For many bioprocesses, precise measurement of media flow rates is vital …
Accessory feed pump for various applications
In many biopharmaceutical or chemical development processes, lab work can be g…
Fluid sample-taking module for high cell density cultures
Automatic sampling of reactor vessels requires careful fluid ma…
Distributor of samples to different devices
The ability to expand your automatic sampling solution provides increased flexi…
Sampling probe suitable for fermenter samples
Accurate, sterile sample collection is vital across a range of biopharmaceuti…
Sampling probe for bioreactor samples
In biopharmaceutical and chemical industries, sampling is vital to develop, maintain, …
Online fraction collector for offline bioprocess analysis
Many bioprocesses require offline analysis of samples to monito…
Online sampling system for larger scale bioprocesses
Accurate sampling is vital for improving a wide variety of industrial…
Automatic sampling system for bioprocess monitoring
An accurate, automated sampling of cultures is a key requirement in th…
Entry-level automated online sampling system
An accurate and sterile sampling of cultures is vital throughout the biopharma…
Pilot high pressure homogenizer
For maximum value, a high-pressure homogenizer that’s suitable for both laboratory and pilot…
High pressure air powered laboratory homogenizer
Offering lab-scale to small pharmaceutical production scale output for in …
High pressure electric laboratory homogenizer
It’s vital that small units for experimentation can scale up with 100% accur…
High pressure industrial homogenizer
For any industrial pharmaceutical process that relies on high pressure homogenization i…
High pressure pilot homogenizer
Biotech and pharmaceutical development programs often require a mixing method that achieves b…
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Compact H2O2 disinfection system
Dry fogging provides safe, effective microbiological cleaning of critical areas in biotech, …
Purification screening kit for large biomolecules
To purify a specific large biomolecule, for example IgM or a virus or vi…
Plasmid process pack for your pDNA purification process
When developing a pDNA purification process for eventual transfer …
Short bed monolithic columns for analytics
Samples taken at various process steps need to be analysed quickly and accurate …
Disposable monolithic columns
Chromatographic monolithic columns for working with large proteins, viruses, VLPs and pDNA requ…
Automated cell culture clarification system
Efficient harvest from the bioreactor is essential to any successful cell cultu…
Single-use temperature sensor
Biopharmaceutical manufacturers are increasingly making use of single-use temperature sensors t…
Single-use conductivity sensor
Biopharmaceutical manufacturers are increasingly making use of single-use conductivity sensors…
Single-use pressure sensor
Biopharmaceutical manufacturers are increasingly making use of Single-use pressure sensors to enha…
Automated dispensing system for bioprocesses
Biopharmaceutical manufacturers require precisely known liquid quantities for …
Lab scale normal flow filtration system
Normal Flow Filtration is frequently used the biopharmaceutical processing industry …
Lab scale tangential flow filtration system
Tangential Flow Filtration is an essential to the biopharmaceutical processing …
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Stories about Cell cultures
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Shakers, incubators, bioreactors – cell culture technology for your production
Cell culture manufacturing is largely used in the production of vaccines, treatments for cancer, and therapeutic proteins and antibodies. There are two sources where to obtain the cell material: through a cell stock, thawing the frozen cells and including them in the culture, and through the isolation of the cells of a donor tissue culture.
Before starting the culture technique, producers carry on cell seeding and observation. Cell seeding guarantees the right cell density, and observation defines if the cells are viable and not contaminated by foreign objects.
Shake flasks are usually the tool in these initial stages. If everything is correct, then you can place the flasks in a CO2 incubator. In it, the concentration of oxygen is lower compared to a non-controlled environment, so the cells can start culturing.
Some biotechnology producers may prefer to use an integrated incubator shaker instead of a flask and a separate incubator, to simplify the process in one place. In this case, you need to define which incubator shaker design fits best to your needs. In other cases, a centrifuge is used to allow the cells to spin down.
Apart from these options, it’s also possible to use a bioreactor as your cell culture equipment. It will help further control, in real-time, the biology of the cells, as well as to fulfill criteria related to quality and efficacy. The most common type that producers use is the stirred-tank bioreactor (STR), which can be easily adjusted for large scale production.
Culture conditions: preparing the environment for your cell lines
Choosing equipment is important. But, to promote cell growth, you need more than cell culture technology; you also need to provide an environment with good conditions for it to work. Researchers use cell lines to conduct different experiments because they can evaluate how a set of cells with the same characteristics respond when submitted to varied conditions and reagents.
When creating these lines, one essential part of the process is to set the culture media formulation that will help cell types to grow. Basic culture medium composition includes glucose, amino acids (the most prominent one being L-glutamine), vitamins, proteins, antibiotics, and inorganic salts. Other components, however, vary according to the outcome expected from those cell lines. The insect cells culture, for instance, benefit from TC-100, while many mammalian cells are supported by RPMI 1640.
Set the optimal conditions for your stem cells culture
Stem cell culture is a valuable asset for research. These cells are particularly interesting due to their nature, as what makes them unique is exactly their ability to differentiate themselves into any cell and self-renew. Nonetheless, it’s precisely because of this that culturing stem cells require extra care and attention in order to provide the right environment for their growth. Stem cells can easily differentiate if the optimal conditions are not reached, but they can also stop responding to growth stimuli, going through the phenomenon of cellular senescence.
