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Nutraceutical Separation Equipment

When it comes to vegan alternative plant-based sources, we always think about replacing meat and dairy. But have you ever thought of replacing food additives such as gelatine, an animal-derived ingredient? Agar-agar is emerging as a seaweed-based alternative. The appeal of agar-agar is that it doesn't need to be refrigerated and can stay at room temperature; it is insoluble in cold water and dissolves well in liquids at over 90° Celsius. You find it in powder format for most industrial applications. But agar-agar processing also delivers flakes or threads for food production.

Agar-agar

Calcium carbonate makes up almost one-twentieth of the earth’s crust. But the abundant mineral is found in many living things, including the human body. However, processing calcium carbonate extracts the multi-purpose material from inorganic sediments, namely limestone, chalk, and marble.

Calcium carbonate

Gummies make everything more colorful. The squishy droplets make a tasty and practical carrier of special ingredients such as CBD oil. Chewing the gum increases the bioavailability of the substance as opposed to vaping. But before the cannabidiol can take effect, it must first be processed through a line of CBD gummy equipment.

CBD gummies

While still forbidden in many countries, there's plenty of room for the use of cannabidiol, or CBD. It’s the second most present active ingredient of the cannabis plant and, no, it won’t get anybody high. What it does, really, once it’s out of the CBD oil processing equipment, is to provide many well-being and health benefits. They go from treating depression and anxiety to relieving pain and unmanageable diseases' symptoms.

CBD oil

Chewable tablets are suitable for patients who have difficulty swallowing. Chewable tablet formulation masks the natural flavors of pharma drugs and alters their aftertaste. But besides the taste, chewable tablets favor the bioavailability of pharmaceutical ingredients.

Chewable tablets

Around a third of your natural protein composition is collagen. But the human body still finds good use for more of it, whether to reinforce joints or aid digestion. Collagen powder processing breaks the chains of amino acids into smaller units, allowing them to be consumed at higher concentrations without changing your diet.

Collagen powder

Echinacea, also known as coneflowers, are brightly hued flowers with distinguished, cone-shaped flower heads. Over 200 medicines in the world are derived from coneflower extracts. Echinacea processing was introduced by Native Americans who were interested in the plant's medicinal qualities.

Echinacea extract

Elderberry falls squarely in the category of superfoods. Every part of the plant (flowers, berries, and bark) is loaded with vitamins, antioxidants, bioflavonoids, and other compounds. However, cyanide in the plant could be lethal if consumed raw, making elderberry extraction processing complex.

Elderberry extract

What’s the only living connection between our present world and the age of dinosaurs? The ginkgo biloba plant. Also known as the maidenhair tree, it is regarded as a living fossil and has been around for more than 200 million years. Ancient civilizations in China were already mastering ginkgo processing centuries ago and the tradition soon flourished around the world.

Ginkgo extract

Panax ginseng is a medicinal plant with a long history steeped in myth. The term “panax” itself is derived from a Greek word for “panacea” or “cure all”. As ginseng processing technology continues to develop, this famous traditional extract keeps finding new applications.

Ginseng extract

The two-piece capsule is a visual shorthand for all types of medical remedies. Advances in technology have made the production of hard-gelatin capsules a convenient delivery method for drugs and other ingested substances. But the simple solution requires micrometric precision to be manufactured to the proper pharmaceutical standards.

Hard gelatin capsules

The nonproprietary name for HPMC – hydroxypropyl methylcellulose – is such a mouthful that it has two abbreviations. Hypromellose is the other one. The non-ionized material offers a safe alternative to gelatin capsules, especially as most common API and excipients are suitable HPMC capsule ingredients.

HPMC capsules

Hyaluronic acid is a natural lubricant found in all mammals. An effective humectant, its molecules can hold a thousand times their weight in water. However, hyaluronic acid extraction is a complex biotechnological process that requires a specialized manufacturing technique.

Hyaluronic acid

Multilayer tablets are a popular fixed-dose combination (FDC) offering a range of release profiles for effective drug delivery. Multilayer tablet technology solves challenges to API consistency, allowing manufacturers to develop formulations from incompatible ingredients while optimizing the release profile for immediate release and controlled release.

Multi-layer tablets

Fish oil was a folk remedy long before scientists identified the nutritional value of essential fatty acids. But Omega 3 processing has come a long way since the days of raw fish parts fermenting in a barrel. In fact, new supplement formulations of polyunsaturated fatty acids (PUFAs) may not use fish at all.

Omega 3 oil

The billions of microbes living in our gut have a significant impact on gastrointestinal health, mood, and behavior. Every individual develops their microbiome community. Probiotic processing technology makes sure that harmful bacteria never outnumber good citizens.

Probiotics

It took the scientific community almost 70 years to agree on the name ‘protein’ and discard the popular alternative, proteid. But protein powder processing still needed another five decades to be commercialized in the 1950s. Once extraction and purification could be industrialized, protein powder soon became a basic staple supplement.

Protein powder

Although popularized recently by NASA this superfood powder made of algae is not a recent discovery. The Aztecs in Mexico and communities around Lake Chad in Africa are known to have harvested and eaten spirulina as a traditional food source. It contains an impressive array of essential nutrients, including complete proteins, vitamins, minerals, such as iron and magnesium, and antioxidants.

Spirulina powder

The cannabis industry is one of the fastest growing in the world with a revenue of $20.47 billion in 2020 which is expected to soar up to $197.74 billion in 2028. The famous cannabis substance that causes marijuana's psychological effects is THC and it was first isolated in 1964. There are two methods of extracting THC from cannabis: solvent-based and non-solvent extraction. Each technique requires different THC oil extraction equipment.

Vitamin C is an essential nutrient, but the human species lost the ability to produce it biologically during the course of evolution. Instead, we source the substance either from whole foods or vitamin C manufacturing. The chemical characteristics of the natural nutrient and processed compound are the same, but supplements offer higher concentrations, especially to persons with nutrient deficiencies.

Vitamin C

Chewy, sweet, and nutritious. Vitamin gummies were a couple’s attempt to get their child to take their essential micronutrients. The idea quickly caught on, and manufacturing vitamin gummies soon grew into a whole new industry.

Vitamin gummies

Bentonite is a clay derived from the alteration of volcanic ash. Bentonite is solid, so after extracting it from the deposits, it has to be crushed and dried to reduce its moisture content up to 15%.

Bentonite

Limestone

Also known as color concentrates for plastics, masterbatches are plastic granules that contain additives for coloring plastics. Their major purpose is to bring vibrance and improve the final product's appearance. In the process of making them, masterbatch production equipment is used to combine two major constituents—colorants and polymer-specific carriers.

Masterbatches

Wear-protection lining prevents excessive wear

Modest space requirement

Sharp top size limitation

Stable operation even if the feed rate fluctuates

Vibration-free

Air classifiers

Ceramic

Chemical

Metal

Mineral

Pharmaceutical

Industrial Separation Equipment

Industrial separation equipment encapsulates the separation process which is to separate components of a liquid mixture, for recovering dissolved solids from liquids. The choice of a suitable technology depends on the identification of the key physical or chemical property, such as size, mass, density, or boiling point, which sets the product of interest apart from the rest of the components. Separation technology is widely used in the pharmaceutical and chemical industries for the isolation of active ingredients and high-purity chemicals. As well as in waste management and recycling industries.

Separation

Connect directly with world leading manufacturers of industrial separation equipment and find technology to build or improve your production line.

Separation - Making.com

Industrial Separation Equipment - Making.com

The battery revolution is as old as the industrial revolution. But batteries only emerged as a viable power source with lithium-ion solutions in the last quarter of the 20<sup>th</sup> century. Today, anything from power tools to automobiles runs on batteries, but advances in battery making equipment are eyeing more ambitious undertakings. Will we ever see battery-powered container ships? Will Battery Energy Storage Systems grow grid-scale successfully? Production technology is steadily moving towards this vision.

Batteries

Ceramics are defined as inorganic and non-metallic materials. Tthey are typically brittle, hard, and elastic as well as resistant to heat and corrosion; in fact, after shaping them into the desired shape, they are heated in an oven called kiln at very high temperatures (1,000 °C to 1,600 °C). Kaolinite and aluminum oxide are the best-known examples of ceramics.

Ceramics

Due to their potential hazardous nature, chemicals are classified for proper identification and safety during production. Chemical classification depends on their properties, structures and functions. In the chemical industry, you can regard them as basic chemicals such as acids, chemical products to produce plastic materials and finished chemicals for use in cosmetology. As a manufacturer or engineer, you want to know their reactivity when using chemical processing equipment.

Chemicals

We carry dozens of metals around every day. The ubiquitous smartphone is built with no less than 20 metals, each with specific behaviors and purposes. Metals are a pervasive class of materials that have defined entire eras of human development. It is no exaggeration to say that metal processing equipment is the core of our metallic world. But, paradoxically, this manufacturing technology itself is mainly made of metal.

The nearly 5,000 known minerals on earth share some characteristics to be classified as minerals – they are inorganic, solid, naturally occurring elements and have a particular chemical formula and an ordered internal geometric structure. However, minerals are not all the same. One way to divide them is based on their physical characteristics such as hardness, luster, color, and shape. For example, the diamonds we use to make jewelry are very hard minerals while talc is a soft mineral; gold is a shiny mineral while others are less so.

Minerals

Eating is more than just nutrition, but we have found ways to increase the nourishing power of our foods. Nutraceuticals manufacturing, from vitamin C powder and probiotics to omega 3 oil, is a concentration of natural ingredients and health supplements that complement our diets. While dietary supplements are not quite haute cuisine, the process of extraction and purification is no less a blend of science and art.

Nutraceuticals

Pharmaceutical powders provide longer shelf life and better stability than liquid dosage forms. But the processing of pharmaceutical powders is crucial for growing segments besides pharmacy. Functional foods and cosmetics formulated with active ingredients and excipients depend on powdered forms to fulfill their promises.

Pharmaceutical powder

Pharmaceutical developments walk side by side with health advances to provide new medicines, treatments, and therapies that have increased life quality and extended life expectancy by years. Pharmaceutical manufacturing equipment helps deliver products to a great deal of the population, but there’s a significant share that doesn’t benefit from them yet. Over 2 billion people cannot get the medicines they need, according to the United Nations Industrial Development Organization, and local production might be a way to provide for these people.

Pharmaceuticals

The building blocks of matter have driven the imagination of philosophers, scientists, and artists for millennia. But, for manufacturers, these elements have a more concrete existence as powders. Powder processing technology conditions these primary materials to create a vast range of products, from chemicals and foods to pharmaceuticals and ceramics.

Powder

Process

Continuous

Classifying

solid

The ATP Turboplex from Hosokawa alpine is an air classifier for ultrafine classifying operations, obtaining with this superfine powders in the fineness range d97 = 5 to 10 µm; with the NG model, finenesses of d97 = 2 µm (d50 = 0.3 µm) are possible.

For ultrafine classifying operations of mineral fillers such as limestone or calcite, dolomite, talc, baryte and perlite, and in the ceramics industry for

Ultrafine air classifier - Making.com

https://making-tst.imgix.net/2014/10/Ultrafine-air-classifier.png

The marketplace for finding innovative production technology

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Gypsum is a naturally occurring mineral that serves many purposes, with the United States producing the largest crude gypsum in the world. Cover walls, ceilings, plasters, fertilizers, cosmetics and some foods: gypsum’s vast applications granted it the recognition of "wonder mineral". Gypsum making equipment helps in making gypsum powder or board for industrial use.

Gypsum

The waste oils from cooking in your kitchen could be transformed to biodiesel. Oily biomass such as soybean, animal fats, or recycled grease make excellent feedstocks to produce high quality alternative transport fuel. Materials are combined with an alcohol in a transesterification reactor that converts the mass into crude biodiesel. The finished product is a low-sulfur, biodegradable fuel that can be used in its pure formulation or in petroleum diesel fuel blends.

Biodiesel

Plastic pollution is one of the biggest climate-related problems mankind has. So what are your options? A bioplastic machine can help create an alternative to traditional plastics. Bioplastics, differently from regular plastics, don’t cause environmental contamination. Also, they don’t contain harmful ingredients and additives. Even with these benefits, the annual production of bioplastics is still less than one percent of all plastic making. However, the market is witnessing steady growth due to a rise in demand.

Bioplastics

The ubiquitous plastic shopping bag was first designed as a reusable carrier. Its inventor, Sten Gustaf Thulin, will have been appalled to see his creation turn into a single-use object. But this disposable tendency is common to all plastic materials, from screw taps to milk carton lining. With plastic recycling equipment, however, plastic waste can be reprocessed and given a second lease of life.

Recycled plastic

Ease of cleaning and simple maintenance, therefore predestined for use when the product is changed frequently

Suitable for off-line and in-line mode even with high airflow rates

Intensive dispersing power

Controlled flow pattern

Wide cut point range from 5 µm to several 100 µm

Classifier mills combine a grinding/milling system with a particle size classifier which continuously recirculates over-sized particles back into the grinding zone. The classifying action ensures a uniform final product with a narrow particle size distribution. Important considerations for choosing a classifier mill include the desired particle size, the maximum particle size variance allowed, and the physical properties of the material.

Classifier mills

Cosmetic

Biomass

According to a legend, Cleopatra soaked her sails in her perfume so that Mark Antony could smell her ships before they arrived. This is to say that, from soaps and shampoos to perfumes, conditioners and pomades, cosmetics have always been highly valued and used for their properties of aesthetic enhancement. Cosmetics are a broad class of topical agents applied for various purposes such as cleansing, protecting, beautifying, or otherwise altering your appearance. As a result, a wide array of processing equipment is used in the cosmetics industry.

Cosmetics

Energy is constantly changing, but it finds rest in a fuel. Once exposed to heat, though, these natural materials release their captured energy. Every aspect of everyday life – from manufacturing to digital services – is powered by the mastery of this complex conversion from fuel to energy.

Fuel

The MikroClassifier CC air classifier from Hosokawa Alpine is a high performance classifier and it can be easily integrated in-line into a grinding system or can be employed off-line as an independent classifying system.

For ultrafine classifying operations in inline mode of all types of fine to medium-fine products, such as acrylate, epoxy-polyester, gypsum, plastics,

High performance classifier - Making.com

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Koala bears diet exclusively on eucalyptus leaves. But the large concentration of cineole in the tree keeps most other predators at bay. Humans, though, discovered ways to extract the substance and use it as a remedy against inflammations and other diseases. The eucalyptus oil production process keeps evolving to maximize yields, ensuring enough eucalyptus forests for koalas.

Eucalyptus oil

Lavender oil is one of the most common essential oils in the market currently. Extracted from the herb Lavandula spp., this essential oil is used as a complementary medicine and as an additive. Studies have shown that lavender oil has sedative, carminative, anti-depressive, and anti-inflammatory properties. Like other essential oils, lavender oil extraction equipment must be capable of distillation, condensation, collection, and separation processes.

Lavender oil

Tea tree oil, also known as melaleuca oil, is an essential oil with immune system stimulants produced mainly in Australia. The tea tree oil manufacturing process starts from the leaves of Melaleuca alternifolia. In terms of market value, the one for tea tree oil was valued at 38.8 million USD last 2017 and is projected to increase to 59.5 million USD by 2025.

Tea tree oil

Rose oil is an essential oil extracted from the petals of either Rosa damascena and Rosa centifolia. Also known as liquid gold, rose oil production originated from Greece and is currently manufactured mainly in Bulgaria, Turkey, and Morocco. Studies have shown that rose oil has medicinal properties, exhibiting anti-inflammatory, anti-infective, and wound healing actions.

Rose oil

Originally created to supply US soldiers with vitamin C in World War II, fruit concentrate has found many other uses. Whether you want to drink soda or eat gummy bears, you need fruit concentrate for the color and flavor. The fruit concentrate processing line involves fruit peelers, conveyor belts, filters, and evaporators that help producers make fruit concentrate with all of the fruit’s original aroma.

Fruit concentrate

Only one percent of the entire plant species on the planet produces essential oils, but that amount has found its way into various products, from perfumes to foods. Flower extraction systems are similarly diverse, and picking the right ones depends on the organic material and the final product.

Flower extract

The rapeseed flower evolved high concentrations of substances that are anti-nutritive at best and toxic at worst. But new varieties developed in the 1970s lowered the content of glucosinolates and erucic acids. From then, the use of oilseed rape spread to several applications, from edible oil to biofuel to animal feed. Rapeseed oil processing technology has thus become foundational to industries spanning food production, energy, cosmetics, and pharmaceuticals.

Rapeseed oil

In the feed sector, it's common to talk about feed as balanced, compound, or concentrate. Many people use one of these terms to refer to any feed mill product. However, the processing of feed concentrates, only requires grinding and mixing. The further transformation into pellets adds is an added value for the market.

Feed concentrates

The humble chamomile flower holds a rich blend of compounds that soothe body and mind. A natural antidepressant and anti-inflammatory, chamomile oil found its way into the earliest pharmacopeia. As more of its properties were discovered, the oil became an elemental ingredient for a vast range of pharmaceutical and cosmetic recipes. Chamomile oil processing equipment developed at the same speed, offering manufacturers multiple production techniques to extract the liquid from the precious flower.

Chamomile oil

Nut oil

The ancient Greeks believed feeding sea buckthorn to their horses would give them a lustrous hide. Indeed, full of lipids and carotenoids, the fruit did contribute to glowing, reddish coats. However, the thorny plant also has benefits for humans. Sea buckthorn processing equipment extracts this unique vegetable oil full of fatty acids. The liquid is a prominent component in various food, cosmetic, and pharmacological preparations.

Sea buckthorn oil

Do you know that the famous classical music composer and pianist Ludwig van Beethoven insisted on drinking a cup of coffee made from exactly 60 pieces of coffee beans? Currently, around 50% of the world’s green coffee beans undergo processing through instant coffee manufacturing equipment to produce instant coffee. The process requires roasting, grinding, brewing, and heating to obtain the extract; the coffee extract will either go through a spray drying process or a freeze-drying process.

Instant coffee

Chinese legend has it that tea was created by accident over 2700 years BC. A servant boiled drinking water for his emperor when leaves from the Camellia sinensis tree fell into it – and the emperor decided to taste the drink. While to make tea nowadays on a medium to large-scale you need tea processing equipment like dryers instead of just a tree and wind blowing it, mythology adds a special flavor to the tea industry story.

Fully tested before arrival at your site, rapid installation and operation

Special conical design means even distribution of the solvent and easy discharge of the raw material

Fitted with 2x 100l extractors for Liquid-Solid extraction of a wide range of products

Use in-house to develop the right parameters to commission a full-size extraction plant saving costs on third-party testing

Solvent Extraction Technology

Food

A beverage is any kind of liquid or drink, usually other than water, made for human consumption. Beverages are further classified into two categories: alcoholic beverages and non-alcoholic beverages. Alcoholic beverages refer to liquids that contain 1% to 75% of liquor and are produced by fermentation such as wine, beer, or distillation such as vodka, rum, tequila. Non-alcoholic beverages are drinks that don’t have any liquor such as tea, coffee, fruit juices, soft drinks, and carbonated beverages. They can be produced premix or postmix, depending on the setup of your production line.

Beverages

Cannabinoids are natural compounds obtained from the Cannabis sativa plant. Delta-9-tetrahydrocannabinol or THC is a psychotropic substance. Cannabidiol, or CBD, is non-psychotropic and often used for nutraceutical purposes. Cannabinoid equipment extracts THC and CBD from the plant and prepares the substance for formulations that treat pain, nausea, anxiety, and inflammations. Cannabinoids are processed in various forms, including creams, capsules, and oils.

Cannabinoids

With over one-third of the population consuming it daily in different forms, coffee is one of the most popular processed beverages worldwide. Not only serving as drinks, but coffee is also often regarded as a culture. Coffee manufacturing is a knowledge-intensive industry. Coffee beans from different regions will reveal different tastes, while the level of caffeine could also be different. When it comes to coffee bean processing, the range of roasts varies from light golden brown all the way to dark. The method of tasting coffee differs between countries, habits, and tools.

Coffee

Essential oils are known as the liquid gems of nature. The sweet-smelling essences impact not just our senses but also our biochemical and cellular make-up. Besides aromatherapy, the products of an essential oil extraction system found applications in pharmaceuticals and foods.

Essential oil

Our food chain starts in the soil, growing crops and livestock. But between the fields and the stores, there is a line of industrial food processing equipment. Processes may be as minimalistic as cleaning fruit and as complex as homogenizing milk alternatives made from pressed legumes. In each case, processing technology is an important link in the food production chain.

Fruit pulp is a mass of pressed fresh fruit not meant for immediate consumption. Production of fruit pulp avoids wasting food and preserves the flavors and nutrient value of the fruit product. Processed fruit pulp is an ingredient in beverages, sauces, baby foods, jellies, smoothies, and bakery products.

Tradition and manufacturing procedures dictate the distinction between fruit juice, puree, and pulp. Still, naming and labeling are complex and depend on regulations, type of fruit, texture, consistency, preservation methods, and sugar or solid content (measured in Degrees Brix). Depending on your desired output, there are various fruit pulper machines for different stages of production that make the process quicker and more efficient.

Fruit pulp

Ancient civilizations discovered that plant extracts were useful for the treatment of pathologies. The origin of plant extraction cannot be specifically verified, but we can infer that the earliest attempts at plant extraction were more intuitive than scientific. Today, the extraction of compounds is a precise process with plant extraction systems complimenting traditional knowledge.

Plant extracts

Whether for personal consumption or agricultural purposes, you process seeds to make them clean and maximize yield. Seed processing equipment includes the steps of polishing, threshing, separation, sorting, and drying. Some cases require additional processes. For example, the extraction of the seed from fruits or vegetables. Or, pressing the seed to extract oil.

Seeds

<span style="font-weight: 400">Spice manufacturing is one of the world's oldest trading products. The word spice refers to any dried part of a plant other than the leaves and is used for seasoning and food coloring. Spices are made from dried barks, roots, berries, and twigs, while green leafy parts of plants are considered herbs. Well-known examples include cinnamon, chilies, star anise, ginger, garlic salt, turmeric, cumin, or pepper, as well as pre-mixed blends such as Masala, Five-Spice Powder, or Old Bay.</span>

Spices

R&amp;D

Batch

Industrial extraction equipment unlocks the valuable compounds hidden away in natural materials. Automated extraction equipment is applied in the pharmaceutical and cosmetic industries to extract active compounds from medicinal plants or herbs. For example, extracting cannabinoids from cannabis plants. But the process is also fundamental to the food industry, recovering various components like aromas, oleoresins, and proteins.  Considerations for selecting suitable extraction technology include the type of plant material to be processed, the extract's heat sensitivity, and the production volume.

Extraction

liquid

Devex pilot extraction plant is perfect for small batch and experimental extraction for natural ingredients to determine the best production parameters.

Before purchasing a full-scale extraction plant you need to exactly determine the correct process parameters for your products. A small form factor pilot

Pilot extraction plant for natural ingredients - Making.com

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The essence of the oceans plays a role in sustainable food production and is an often overlooked superfood. Compared to traditional crops, algae requires minimal land and resources. Processed into food powders like spirulina or chlorella or into seaweed snacks, algae is considered to be one of the foods of the future. It provides you with vitamins, minerals, and proteins and assists the world in food security concerns. It is a popular ingredient in the supplement and cosmetics industry too.

Algae

True tailor-made extraction solution

Able to recover a wide range of natural extracts

Designed for easy raw material discharge, saving time between batches

Huge range of options and customisation

Devex extraction plants for recovery of essential oils, oleoresins, aromas, natural extracts and proteins are tailor-made for your production needs.

Bespoke extraction plants using the latest technology can improve your efficiency and reduce costs when developing natural extracts for the food and

Extraction plant for natural ingredients - Making.com

https://making-tst.imgix.net/2017/05/Devex-extractor.png

<h3>Convert solutions into solid fibers to facilitate solubility</h3>
In the nutraceutical industry, bioactive compounds that make the basis of most nutraceuticals typically have <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806606/" target="_blank" rel="noopener">low aqueous solubility</a>, leading to poor bioavailability. Electrospinning techniques can address this challenge.

The method and manufacturing process applies a high voltage the inclusion solution pumped through a needle. The electric field forces the droplet into a jet stretched to form a solid fiber. The ultrafine material can be woven into microcapsules that dissolve quickly.

Nutraceutical Separation Equipment

Which nutraceutical separation technology do you need?

Ultrafine air classifier

High performance classifier

Pilot extraction plant for natural ingredients

Extraction plant for natural ingredients

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