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Serums making equipment

Cosmetic serums are a very light formulation with a high density of active ingredients dispersed in oil, water, or gel. This makes serums well suited to the delivery of vitamins, antioxidants, and anti-aging ingredients, but provide less moisturization and protection. Serum production is mainly divided into stages related to optimal mixing and preventing degradation of the active ingredients.

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Most important considerations of equipment for making serums


When making cosmetic serums, you start by preparing the oil-soluble and water-soluble constituents separately. Add active ingredients after any thermal treatments as heat may damage or destroy them. Water-based serums will typically comprise oil solubles in very low concentrations of a few percent, active ingredients in a relatively high concentration, and water-solubles forming the majority of the solution. An emulsifier facilitates the distribution of oil solubles, and a preservative protects against microbial growth.


Equipment for making serums requires mixers to prepare the initial stages and to reach a uniform consistency. These may also include thermal functions to assist the incorporation of heat-stable ingredients. You then join the two phases with the help of an emulsifier, and may now introduce your active ingredients safely. Production nuances present with the variety of serum applications, such as acne management, anti-aging, skin-shining, and the reduction of wrinkles. As a result, the selection of your formulation and the necessary accommodations to produce it successfully are important. With oil-based serums, you don’t need to process a water phase entirely for example. Gel-based serums require mixing equipment able to develop the gelling phase.

Alternative options for serum bases

Gel-based serums provide better moisturization and need a gelling agent to reach the desired consistency and texture. You still need an emulsifier to incorporate lipid components, and preservatives to prevent microbial growth. Contrary to water-based serums, their oil-based counterparts contain no water, so they don’t need emulsifiers, and to some degree preservatives. Emulsifiers can strip away the natural oils of the skin and may not be desirable in some circumstances. Consumers may also prefer preservative-free cosmetics, though these are very safe ingredients essential to maintaining shelf life in hydrated formulations. Common bases for such serums include Argan oil and Jojoba oil.

Regulatory compliance for crafting cosmetics


Regulations for production and sale of cosmetic serums vary from country to country, but prioritize safety and transparency of ingredients. The EU has defined its expectations in EU Regulation 1223/2009, for example, and includes an extensive list of banned substances. It also highlights good manufacturing practices, and requires accessibility of relevant data to track economic and medical aspects of the serum. You need to appoint a responsible party, and develop an ongoing conversation with your regulatory agency regarding the safety of your serum.


How homogenization gives you consistency

One of the most important aspects of serum production is the homogenization of its composition. A reliable serum should maintain the same look and feel in every batch. Different ingredients behave differently in solution, and clumping can produce irregularities in the texture as well as discrepancies in relative potency. When selecting equipment for making serums, consider the needs of your formula to find the optimal fit. If clumping can be an issue, use agitators to help ingredients disperse into the mixture. Prior to adding active ingredients, you may also want to heat elements to facilitate even incorporation for a smooth, uniform outcome.

Processing steps involved in serums making

Which serums technology do you need?

GMP homogenizing system

GMP homogenizing system

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Cost-effective homogenizing and emulsifying system

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Monobloc filler and capper

Monobloc filler and capper

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Vertical cartoning solution for fragrance and skincare products

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Industrial recirculating chiller for laboratory applications

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Laboratory homogenizer for pharmaceutical and biotech applications

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Automatic bottle filling and capping line

Automatic bottle filling and capping line

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Benchtop peristaltic dispenser

Benchtop peristaltic dispenser

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Thin film dryers

Thin film dryers

Dry dissolved or slurried crystallizing or amorphous products to a pourable powder.

Horizontal thin film evaporators

Horizontal thin film evaporators

Horizontal thin film evaporators can increase the residence time of the product and achieve …

Semi-automatic vial crimper

Semi-automatic vial crimper

In a small production line, crimping vials manually can cause fatigue to your operator due to mul…

Manual ampoule filler

Manual ampoule filler

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Laboratory liquid viewer for transparent glass bottles

Laboratory liquid viewer for transparent glass bottles

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Laboratory liquid viewer for colored glass bottles

Laboratory liquid viewer for colored glass bottles

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Benchtop piston filling equipment for vials in trays

Benchtop piston filling equipment for vials in trays

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Benchtop ampoule opening and closing equipment

Benchtop ampoule opening and closing equipment

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Evaporator for heat sensitive products

Evaporator for heat sensitive products

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Cosmetic cream filler

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Vibrating sieve for liquid solid separation

Vibrating sieve for liquid solid separation

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High pressure air powered laboratory homogenizer

High pressure air powered laboratory homogenizer

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High pressure electric laboratory homogenizer

High pressure electric laboratory homogenizer

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High pressure industrial homogenizer

High pressure industrial homogenizer

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High pressure pilot homogenizer

High pressure pilot homogenizer

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Single head capper

Single head capper

For the stand-alone capping of bottles of up to 30 litre capacity for smaller-scale production you need a r…

Servo controlled filler

Servo controlled filler

For food and non-food liquid products that are high foam or have a high viscosity a specialist filling…

Multi-head capper

Multi-head capper

For the stand-alone capping of bottles of up to 2.5litre capacity you need a robust and flexible machine wit…

In-line monoblock linear filler & capper

In-line monoblock linear filler & capper

In many food, chemicals and cosmetic industry processes it is vital to have a …

Compact monoblock filler

Compact monoblock filler

Filling and capping bottles and pots for food, chemical and cosmetics industries using separate machi…

High-pressure homogenizer

High-pressure homogenizer

When processes call for homogenized emulsions with extremely fine particle sizes the traditional to…

Agitator for low viscosity media

Agitator for low viscosity media

Reliably agitating fluids in open or pressure-less vessels in a laboratory or small scale pr…

Agitator for medium viscosity media

Agitator for medium viscosity media

Mixing fluids of medium viscosity for many production processes requires an agitator wit…

Jet flow agitator for high-viscosity media

Jet flow agitator for high-viscosity media

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Laboratory dispersing machine for low-viscous masses

Laboratory dispersing machine for low-viscous masses

Laboratory mixers have not always been easy to work with.  Getting al…

In-line laboratory dispersing machine

In-line laboratory dispersing machine

Innovators in a wide variety of industries need laboratory equipment on which processe…

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