Making Dry Powder Inhalers
Find innovative production technology for making dry inhaler powder and connect directly with world-leading specialists
The click and puff of inhalers is a universal signal for respiratory conditions. Inhalers quickly grew into preferred drug delivery systems for asthma and COPD. Dry inhaler powder formulation produces a more stable drug than liquid dosage forms. Moreover, inhaler ingredients are more resistant to bacterial growth.
Select your dry inhaler powder process
Tell us about your production challenge
Mill inhaler powder materials to achieve good particle size distribution
The recommended particle diameters for optimal aerosols preparation range from 1 to 5 µm. Smaller particles clump together while larger diameters lose their cohesive properties.
Reduce the diameters of coarse particles before mixing the ingredients for dry inhaler powder formulation. Jet milling applies high-impact forces combined with compressed gas to produce micro sizes.
Engineered blends improve the processing of dry inhaler powder formulations
Add carrier particles to the API mix to improve the processing properties of bulk powders. However, the particles of drugs and carriers must be chemically compatible. Their reciprocal adhesive forces need to be powerful enough to hold the mixture together during filling and storage. At the same time, they need to be quickly detachable during aerosol administration.
Coarse lactose monohydrate improves powder flowability during manufacturing and provides good carrier-particle separation. Lactose blends are formulated with drug contents of 5% (w/w) or less.
HPMC capsules are more stable for mono-dose inhaler systems
Mono-dose inhalers deliver a single serving of powder formulation by loading a capsule into the device before each use. Depending on the system, the capsule is activated by sheer force opening, needle-piercing, or cutting the capsule. But moisture content is a critical consideration for each technique.
Very dry conditions apply pressure on traditional gelatin-based capsules, causing them to crack before use. Hypromellose capsules (HPMC), on the other hand, is less hygroscopic and behaves well in both wet and arid environments.
Processing steps involved in dry inhaler powder making
Which dry inhaler powder technology do you need?
Super high shear mixer for nano to micron powders
In scenarios where precision powder mixing, particle surface modificati...
Lab mixer for powder formulations
Creating uniform powder blends in pharmaceutical labs presents challenges, like achieving...
Powder characteristic evaluation
In laboratory and research environments, accurately assessing the flow properties and behav...
Dpi blister strip weighing system
In the production of dry powder inhalers (DPI), precise control of the fill weight in bli...
Dpi inhaler production system
In the pharmaceutical industry, manufacturing devices like dry powder inhalers (DPIs) presents...
Commercial blister filling solution for dry powder
In pharmaceutical manufacturing, achieving precise, high-speed blister...
Micro-dosing system for inhalation blisters
In pharmaceutical production, the precise and efficient micro-dosing of active...
Disc filler for dry powder inhalers
In the production of dry powder inhalers (DPIs), accuracy and consistency in filling di...
Custom automation for drug-device filling and assembly
Pharmaceutical companies developing innovative drug delivery syste...
Dry powder filling isolator for cgmp production
In pharmaceutical manufacturing, ensuring sterility and precision in filli...
3D powder mixer for active pharmaceutical ingredients
Proper mixing and homogenization are essential to achieve a reliabl...
Modular assembly line for healthcare products
Assembly setups need to be constantly rethought and reconfigured to adapt qu...
High containment big bag discharge docking system
The discharge of materials demands strict containment, particularly in ...
Accurate multiple dosing system for powders
Dosing multiple powders in a batch process is time inefficient, especially whe...
Hygienic floor scale
The food and pharmaceutical industries require maintaining high levels of sanitations as well as logisti...
Hygienic mobile scale
Having a reliable and accurate weighing and measuring solution is absolutely essential, especially in t...
Fast gravimetric powder microdosing 50 - 200 g
Micro-dosing powders of high-value food or chemical products can be challen...
Gravimetric powder microdosing 2 - 100 g
Powders and granules are commonly dosed for the manufacturing of pharmaceuticals, ...
Gravimetric powder microdosing 0.400 - 2 g
If you need to process high value food, pharmaceuticals or chemicals, there is ...
Single-use powder handling bag
Containers for handling pharmaceutical and biopharmaceutical powders may be disposable, to av...
API powders storage bottle
Users who prefer rigid storage over single-use pharma charge bags, require lightweight solutions ...
Single-use containment valve
Safe transfer of liquids and hazardous powders into systems can be a challenge in pharma, bioph...
High containment closing system
Pharma and biopharma laboratories need fast effective solutions for tightly sealing bags for...
High containment sampler
Drawing a sample for evaluation from a running process is not a simple task, especially when dealing...
Metal detector for pharmaceutical powders
Powdered and granulated pharmaceuticals require careful screening against metal ...
R&D V-type powder blender
Many pharmaceutical processes rely on the complete blending and homogenizing of different powdered...
Pharmaceutical container lifter
Moving larger or heavier containers from height is out of the scope for standard handling eq...
Vacuum sack lifter
In the production of pharmaceuticals and other high-hygiene environments, manual handling of inputs or int...
Bin blender
Many pharmaceutical processes require the blending of powders or other granular ingredients, the mixing of settled...
Container lifter
Container handling in the pharmaceutical industry brings its own set of unique challenges. Traditional barrel...
Mobile drum lifter
The production of pharmaceuticals and other hygienic products often requires the handling of large and bul...
Powder transfer vessel
Intermediate bulk storage of pharmaceutical product requires specialist containers. For increased effi...
GMP Jib crane
Vacuum manual handling systems are the ideal way of quickly and safely moving small to medium sized loads in all...
Small feeder with flexible wall hopper
In many laboratory applications and production processes, smaller quantities of powd...
Metal detection system for aluminum packages
The magneto reflection system is ideal for detection of metals in aluminium f...
Checkweigher for sachets and sticks
The checkweighers for multiple lanes have a 1.5 times faster response speed and 2 times...
Fluid bed dryer for production scale
Fluidized bed drying (FBD) is a common process in the pharmaceutical industry for dryi...
Fluid bed dryer for lab scale
Fluidised bed drying (FBD) is a common process in the pharmaceutical industry for drying compo...
Fluid bed dryer and mixer for lab scale
Designed for pharmaceutical R&D, a lab-scale fluid bed dryer and mixer/granulat...
Magnetic agitator
Reliable mixing and agitation are essential to any quality production process that involves a fluid. This n...
Centrifugal disc filter
The pharmaceutical and bioprocess industries need filtration processes of particularly high quality t...
Spherical dryer
Drying vessels that are simple, reliable, and easy to maintain increases product quality and process efficienc...
Filter dryer
The pharmaceutical and bioprocess industries need filtration processes of particularly high quality to ensure the...
Transfer system for high-containment environments
A high-performance transfer port system that combines ultimate safety, ...
Half-suit tester
Designed to allow operators to perform sterility testing in an aseptic environment providing assurance of mat...
Glove tester
Testing device of the containment capability of gloves, which is as important as the other parts of the integrate...
Rotary vacuum dryer
Powdered products tend to agglomerate during vacuum drying. This adds an additional step to the productio...
Premium vacuum conveyor
When you have a need to tailor make your conveyor and still have the high requirement on hygiene, e.g...
Horizontal vacuum dryer with eccentric agitator
Conventional dryers are inefficient and can lead to significant mechanical...
Vacuum tray dryer with clean-in-place system
Cabinet tray dryers can be difficult to clean, making their use difficult for...
Horizontal paddle vacuum dryer
Agitated vacuum dryers can be difficult to clean which makes them unsuitable for multi-produc...
Laboratory-scale vacuum tray drying oven
Vacuum drying is used to remove moisture from sensitive materials. Drying small ba...
Bellows for pharmaceutical powders
Thermal and mechanical changes can lead to stresses in industrial piping systems. These ...
High containment segment ball valve
Valves fitted in blenders and dryers can have dead spaces that prevent complete process...
Removable GMP compliant connections for tubing
Tubing frameworks can have rough welding joints, corners and sharp angles t...
Negative pressure isolator
Used for products biologically hazardous, that also require minimized cross contamination.
Vertical laminar flow cabinet
HEPA filtered vertical laminar airflow (down flow) creates an ISO 14644-1 (Class 5) work area ...
Biological safety cabinet class III
Specially designed for the handling of microbiological agents, when working with indige...
Hygienic floor scale with lifting device
The food and pharmaceutical industries require maintaining high levels of sanitati...
Flexible contained powder charging solution
Filling of transportation bags and discharging them into mix tanks or reactor ...
Flexible contained charging for split butterfly valves
Poly bottles with split butterfly valves are often used to transfe...
Dosing machine for nonfree-flowing powders
Fill poorly flowing powders, dry syrups and similar substances into various gla...
Restricted-access barrier systems
Create a physical barrier between the operator and the product. More flexible than an iso...
Flexible contained handling of powder transfer bags
Filling of transportation bags and discharging them into mix tanks or...
Crimping system
Flexible disposable containment systems in the form of specially designed plastic bags are an excellent choice...
Flexible contained drum transfer system
Transferring powders from drums to process equipment such as reactors or mills can ...
Flexible contained powder discharge into FIBC’s
Flexible intermediate bulk containers known as FIBC’s are commonly used in...
Flexible contained powder discharge into drums
Powdered products are handled every day in the pharmaceutical and bioproces...
Checkweigher for stand-up pouches
When working with several lines of stand-up pouches, you can benefit from controlling the...