Let's make dry powder inhalers
Find innovative production technology for making dry inhaler powder and connect directly with world-leading specialists.
The click and puff of inhalers is a universal signal for respiratory conditions. Inhalers quickly grew into preferred drug delivery systems for asthma and COPD. Dry inhaler powder formulation produces a more stable drug than liquid dosage forms. Moreover, inhaler ingredients are more resistant to bacterial growth.
Which dry inhaler powder equipment do you need?
Modular assembly line for healthcare products
Assembly setups need to be constantly rethought and reconfigured to adapt qui…
Bellows for pharmaceutical powders
Thermal and mechanical changes can lead to stresses in industrial piping systems. These s…
High containment segment ball valve
Valves fitted in blenders and dryers can have dead spaces that prevent complete processi…
High containment sampler
Drawing a sample for evaluation from a running process is not a simple task, especially when dealing …
Removable GMP compliant connections for tubing
Tubing frameworks can have rough welding joints, corners and sharp angles th…
Accurate multiple dosing system for powders
Dosing multiple powders in a batch process is time inefficient, especially when…
High containment big bag discharge docking system
The discharge of materials demands strict containment, particularly in t…
Hygienic floor scale
The food and pharmaceutical industries require maintaining high levels of sanitations as well as logistic…
Hygienic floor scale with lifting device
The food and pharmaceutical industries require maintaining high levels of sanitatio…
Hygienic mobile scale
Having a reliable and accurate weighing and measuring solution is absolutely essential, especially in th…
Fast gravimetric powder microdosing 50 - 200 g
Micro-dosing powders of high-value food or chemical products can be challeng…
Gravimetric powder microdosing 2 - 100 g
Powders and granules are commonly dosed for the manufacturing of pharmaceuticals, n…
Gravimetric powder microdosing 0.400 - 2 g
If you need to process high value food, pharmaceuticals or chemicals, there is n…
High containment closing system
Pharma and biopharma laboratories need fast effective solutions for tightly sealing bags for …
Single-use containment valve
Safe transfer of liquids and hazardous powders into systems can be a challenge in pharma, biopha…
API powders storage bottle
Users who prefer rigid storage over single-use pharma charge bags, require lightweight solutions f…
Metal detector for pharmaceutical powders
Powdered and granulated pharmaceuticals require careful screening against metal c…
Single-use powder handling bag
Containers for handling pharmaceutical and biopharmaceutical powders may be disposable, to avo…
R&D V-type powder blender
Many pharmaceutical processes rely on the complete blending and homogenizing of different powdered …
GMP Jib crane
Vacuum manual handling systems are the ideal way of quickly and safely moving small to medium sized loads in all …
Powder transfer vessel
Intermediate bulk storage of pharmaceutical product requires specialist containers. For increased effic…
Container lifter
Container handling in the pharmaceutical industry brings its own set of unique challenges. Traditional barrel …
Mobile drum lifter
The production of pharmaceuticals and other hygienic products often requires the handling of large and bulk…
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Bin blender
Many pharmaceutical processes require the blending of powders or other granular ingredients, the mixing of settled …
Pharmaceutical container lifter
Moving larger or heavier containers from height is out of the scope for standard handling equ…
Vacuum sack lifter
In the production of pharmaceuticals and other high-hygiene environments, manual handling of inputs or inte…
Fluid bed dryer for production scale
Fluidized bed drying (FBD) is a common process in the pharmaceutical industry for dryin…
Fluid bed dryer for lab scale
Fluidised bed drying (FBD) is a common process in the pharmaceutical industry for drying compou…
Fluid bed dryer and mixer for lab scale
Designed for pharmaceutical R&D, a lab-scale fluid bed dryer and mixer/granulato…
Laboratory-scale vacuum tray drying oven
Vacuum drying is used to remove moisture from sensitive materials. Drying small bat…
Horizontal paddle vacuum dryer
Agitated vacuum dryers can be difficult to clean which makes them unsuitable for multi-product…
Vacuum tray dryer with clean-in-place system
Cabinet tray dryers can be difficult to clean, making their use difficult for …
Rotary vacuum dryer
Powdered products tend to agglomerate during vacuum drying. This adds an additional step to the production…
Horizontal vacuum dryer with eccentric agitator
Conventional dryers are inefficient and can lead to significant mechanical …
Small feeder with flexible wall hopper
In many laboratory applications and production processes, smaller quantities of powde…
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Contact usMill inhaler powder materials to achieve good particle size distribution
The recommended particle diameters for optimal aerosols preparation range from 1 to 5 µm. Smaller particles clump together while larger diameters lose their cohesive properties.
Reduce the diameters of coarse particles before mixing the ingredients for dry inhaler powder formulation. Jet milling applies high-impact forces combined with compressed gas to produce micro sizes.
Engineered blends improve the processing of dry inhaler powder formulations
Add carrier particles to the API mix to improve the processing properties of bulk powders. However, the particles of drugs and carriers must be chemically compatible. Their reciprocal adhesive forces need to be powerful enough to hold the mixture together during filling and storage. At the same time, they need to be quickly detachable during aerosol administration.
Coarse lactose monohydrate improves powder flowability during manufacturing and provides good carrier-particle separation. Lactose blends are formulated with drug contents of 5% (w/w) or less.
HPMC capsules are more stable for mono-dose inhaler systems
Mono-dose inhalers deliver a single serving of powder formulation by loading a capsule into the device before each use. Depending on the system, the capsule is activated by sheer force opening, needle-piercing, or cutting the capsule. But moisture content is a critical consideration for each technique.
Very dry conditions apply pressure on traditional gelatin-based capsules, causing them to crack before use. Hypromellose capsules (HPMC), on the other hand, is less hygroscopic and behaves well in both wet and arid environments.
