Let's make microtablets
Find innovative production technology for making microtablets and connect directly with world-leading specialists.
Microtablets range between 1 and 4 millimeters, making the dosage form an excellent delivery system in polypharmacy. The size of the products makes them easier pills to swallow, but microtablets production brings a unique set of complexities.
Which microtablets equipment do you need?
Fluidized bed system for the granulation and drying of pharmaceuticals
Pharmaceutical industries employ several processe…
Pharmaceutical tablet coating machine
Tablet coating requires spraying, mixing, and drying procedures that must be carried o…
Premium vacuum conveyor
When you have a need to tailor make your conveyor and still have the high requirement on hygiene, e.g.…
High-sensitivity metal detection system
Highly efficient metal detector with enhanced quality control and reporting capabili…
A check weigher that is equipped with high speed/high accuracy force balance load cell. It meets stringent accurac…
Sorption dehumidifier with air-chilled condenser
It is not always possible to duct out the wet air from a dehumidifier serv…
Small portable dehumidifier
Water damaged areas require dehumidification to limit the damage and prepare the area for restora…
Sorption dehumidifier for large temperature differences
Small, humid areas can be difficult to dehumidify in humid ambient…
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Select your microtablets process
Tell us about your production challenge
Align the punches in multi-tip tooling technology with precision
The millimetric dimensions of microtablets make compression force harder to control than for larger-sized tablets.
Adopting multi-tip tooling in your microtablets production process multiplies overall compression power by the number of tips in the equipment. While this technique distributes the weight in microtablets more evenly, misalignment between the upper and lower punch results in faulty compression.
Extend the coating process in microtablets production
The reduced diameter of microtablets gives them a larger surface area relative to regular-sized tablets. This physical property increases the speed of drug release once ingested and decreases the diffusion rate of the active pharmaceutical ingredients.
Microtablets designed for delayed release require an extended coating process. Spray coating using a fluidized bed system achieves uniform coats, but a high spray rate can develop cracks down the line if temperatures are too low for adherence.
Set your friability limit to 1% of body weight in minitablet production
The friability threshold of microtablets must not exceed a reduction of 1% in the total weight of the tablets.
Select a dusted sample with a total body weight of 6.5 g a place it into a rotating drum. After the rotating cycle is completed, dust the microtablets again and measure the weight. Check the products for chips or cracks.