Let's make microtablets
Microtablets range between 1 and 4 millimeters, making the dosage form an excellent delivery system in polypharmacy. The size of the products makes them easier pills to swallow, but microtablets production brings a unique set of complexities.
Which microtablets equipment do you need?
Premium vacuum conveyor
High-sensitivity metal detection system
Checkweigher
Sorption dehumidifier with air-chilled condenser
Small portable dehumidifier
Sorption dehumidifier for large temperature differences
Sorption dehumidifier for deep drying
Dehumidifier for difficult wet airflows
Sorption dehumidifier for overpressured rooms
Heat recycling sorption dehumidifier
Industrial desiccant dehumidifier
Large scale desiccant dehumidifier
Customizable dehumidifier
Small feeder with flexible wall hopper
Entry-level high-shear mixer for drug formulation
Granulation line of mixer and fluid bed dryer
Lab scale single layer tablet press
Rotary tablet press
Single layer tablet press
Industrial blister packaging machine
Laboratory Tablet Press
Particle analysation monitor
Clinical trial lab sealer for a laminar airflow bench
Semi-automatic forming and sealing blister machine
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Select your microtablets process
Tell us about your production challenge
Align the punches in multi-tip tooling technology with precision
The millimetric dimensions of microtablets make compression force harder to control than for larger-sized tablets.
Adopting multi-tip tooling in your microtablets production process multiplies overall compression power by the number of tips in the equipment. While this technique distributes the weight in microtablets more evenly, misalignment between the upper and lower punch results in faulty compression.
Extend the coating process in microtablets production
The reduced diameter of microtablets gives them a larger surface area relative to regular-sized tablets. This physical property increases the speed of drug release once ingested and decreases the diffusion rate of the active pharmaceutical ingredients.
Microtablets designed for delayed release require an extended coating process. Spray coating using a fluidized bed system achieves uniform coats, but a high spray rate can develop cracks down the line if temperatures are too low for adherence.
Set your friability limit to 1% of body weight in minitablet production
The friability threshold of microtablets must not exceed a reduction of 1% in the total weight of the tablets.
Select a dusted sample with a total body weight of 6.5 g a place it into a rotating drum. After the rotating cycle is completed, dust the microtablets again and measure the weight. Check the products for chips or cracks.
