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<h3>Enrich the LAB cultivation medium with magnesium and manganese</h3>
<p>Lactic acid bacteria (LAB) are used in many food products, but this strain requires a complex nutrient environment to develop.</p>
<p>Add manganese sulfate or magnesium sulfate to your cultivation medium to boost the <a href="https://www.cambridge.org/core/journals/journal-of-dairy-research/article/cultivation-media-for-lactic-acid-bacteria-used-in-dairy-products/6EB10962C6E5239A0A00D8E373B355DF" target="_blank" rel="noopener">metabolic activity</a> of LAB. The minerals also act against external oxygen radicals and provide anaerobic growth for the bacteria.</p>


<p>Freeze-drying your bacteria converts the probiotics into dried powder. However, freezing at very low temperatures and dehydration under vacuum stress the cells.</p>
<p>A cryoprotectant increases the viability of the cells, but different materials achieve different levels of protection. An emerging technique <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500555/" target="_blank" rel="noopener">combines</a> trehalose, sodium ascorbate, and skim milk to register a cell survival rate of around 75%.</p>


Preserve cell viability with cryoprotectants when using probiotics processing technology

<p>Probiotic strains may produce acidity, affecting the stability of the product. Probiotics processing technology such as refrigerators reduce the pH value of bacterial cells in a phenomenon known as <a href="https://onlinelibrary.wiley.com/doi/full/10.1111/j.1745-4603.2007.00129.x" target="_blank" rel="noopener">post-acidification</a>.</p>
<p>The Lactobacillus delbrueckii ssp. Bulgaricus (STLB) species demonstrates a high relative drop in pH levels. On the other hand, Bifidobacterium has a lower capacity for developing acids, making strains like the Bifidobacterium lactis more resistant to post-acidification.</p>


Higher pH stability makes Bifidobacterium more resistant to post-acidification 

<h3>Ensure probiotic concentrations in end products meet claim requirements</h3>
<p>Different regions around the world have separate <a href="https://www.crnusa.org/sites/default/files/pdfs/CRN-IPA-Best-Practices-Guidelines-for-Probiotics.pdf" target="_blank" rel="noopener">regulatory labeling requirements</a> for probiotic products. Proprietary blends are permitted, but individual dietary ingredients within a proprietary blend should be listed in descending order by their Colony Forming Units (CFU).</p>
<p>Any benefits declared about the strains should be backed up by scientific evidence that the amounts provided in the product are consistent with the information supporting the claim.</p>


Bioprocessing

Centrifuging

Dosing

Drying

Encapsulation

Filling

Filtration

Inspection

Measurement &amp; Control

Mixing

Sterilizing

Let's make probiotics

Some of the vaccines in use today were originally developed decades ago. But advances in research and vaccine manufacturing equipment provide immunizations from bacterial and viral diseases to more people every year. The Covid-19 pandemic highlights the urgent need to scale up the production of vaccines and ensure a reproducible manufacturing environment.

Vaccines

Insulin is a hormone that controls blood glucose levels produced by the beta cells in the pancreas. As a medication, insulin was discovered by Frederick Banting and Charles Best in 1921, for which they were awarded a Nobel Prize in 1923. The insulin production process involves manipulating the biological precursor to insulin and cultivating it inside bacteria.

Insulin

Cell culture has been, over a little more than 100 years, an important method of research in laboratories. But medicine developments aside, we wonder if even the most positive of idealists could have also believed that cell cultures would possibly change the way – and what – we eat. From the lab to the dining table, there’s cell culture equipment to make even the unimaginable possible.

Cell cultures

The billions of microbes living in our gut have a significant impact on gastrointestinal health, mood, and behavior. Every individual develops their microbiome community. Probiotic processing technology makes sure that harmful bacteria never outnumber good citizens.

Probiotics

The word parenteral comes from Greek and means outside the intestine (para=outside and enteron=intestine). In fact, when it comes to parenterals, we are referring to those dosage forms that are administered directly into the bloodstream using a hypodermic needle, avoiding going through the gastrointestinal tract. Using parenteral filling equipment, parenteral solutions are placed in containers such as vials, syringes, or ampoules.

Parenterals

What does a $300,000 burger taste like? Meat. The first lab-grown burger took two years and 20,000 strands of muscle tissue to produce. But with rapid advances in cultivated meat processing technology, non-animal meat products can now take a lot shorter to prepare. And cost much less.

Cultivated meat

Getinge Applikon is the only company that can take you from the initial screening stage up to full-scale production using the same platform. This minimizes scale-up risks and guarantees the shortest time to market for your new product development.

Adaptive PID control guarantees the most accurate control of your process parameters, preventing errors

User definable control loop configuration offers a unique flexibility in adding other sensors to your process

Define, store, copy and reload process configurations to reduce your experiment set up time

Can be used with classic and with fluorophore sensors (pH and oxygen), biomass sensors for measurement and control to maximize process information

  Due to the GAMP compliant development documentation, the system can be used in validated processes

Success with bioprocesses is all about controlling the environmental conditions controls so you can replicate processes consistently. Good insight and easy adjustment of pH, Temperature, Dissolved Oxygen, Foam/Level and Agitation are crucial for any biopharmaceutical process.


<h2>Easy to use control for lab scale operation</h2>
The ez2-Control from Getinge Applikon is an easy to use control and measurement system for bioreactors and fermentors. The bioreactor control system offers high accuracy, a good insight and easy adjustment of pH, Temperature, dissolved Oxygen, Foam/Level and Agitation, which are crucial for any biopharmaceutical process.

The colour touch screen interface guides the user through the operation.  The adaptive control features allow the user to focus on the process while the controller keeps tight control on the important process parameters.

The new web-interface for ez2-Control with advanced user management option provides a clear overview of the bioprocess parameters. Also it allows back-ups, copies and predefined settings of configurations to be simply shared via USB.

The ez2-Control can be used to control a large variety of reaction environments: From autoclavable bioreactors, steam in place bioreactors, to Appliflex single use bioreactors, milipore Cell Ready single use bioreactors or HyClone SUB bioreactors.

Lab scale Bioreactor controller

R&amp;D

A bioreactor is an engineered system designed to support and control a biologically active environment. The volume of the reactor, suitability for photosynthesizing organisms, level of scalability and control, and the type of installed sensors are all important considerations when choosing a bioreactor. Bioreactors are typically used for cell culture, microbial culture, biopharmaceutical, and chemical development processes. They are also used for photosynthesizing commercial organisms such as algae and bacteria and fermentation applications.

Bioreactor systems

Single-use technologies are increasingly being used in the biotech industry due to lower costs, lower risk of cross-contamination, flexibility, and convenience. A single-use bioreactor uses disposable bags instead of a culture vessel to carry out the bioprocess. Using disposable bags, instead of reusable bioreactors, can help reduce the setup time and the time between production cycles. It also reduces sterilization demands for vessel reuse, leading to significant cost savings. In addition to single-use bags, single-use sensors are also employed for efficient and low-cost bioprocessing. Single-use applications are especially suitable for the production of biopharmaceutical products.

Single use systems

Pharmaceutical

Batch

Biotech equipment is used for the processing of biological organisms to develop new healthcare-related products. Selecting suitable equipment requires consideration of the process objectives and requirements, the scale of production, and the specific health and safety regulations. Biotech equipment finds applications production of biodegradable plastics, and biofuels as well as in health care.

The fermentation process stimulates enzymatic activity in organic substrates to transform their chemical composition. Fermentation is aided by storying the biomaterials in anaerobic environments, allowing the microorganisms to decompose their nutrient structures. The process is integral to some of the most popular products throughout time such as wine, beer, cheese, and kimchi. But besides the food sector, fermentation is also an important stage in the industrial manufacturing of chemicals, pharmaceuticals, and biofuels.

Fermentation

A crucial step before your products leave the production line is a quality check for dosage and standards. Equipment for measurement and control employs a range of technologies to detect inconsistencies in volumes, sizes, weights, and fill levels as well as to inspect goods for quality against a set of criteria. Specialized systems allow you to minimize the probability for error to its lowest possible, ensuring that both products and packaging meet your benchmarks.

A biopharmaceutical is a drug in which the active substance is manufactured or extracted from biological origin materials. They are usually produced in bioreactors by plant cells, microbial cells, yeast cultures, or mammalian cells. Also known as biomanufacturing, they are used to either treat or diagnose and prevent a patient’s medical condition or disease. Biopharmaceuticals are typically complex macromolecules administered by injection or infusions, and examples include vaccines, serums, and insulin.

Biopharmaceuticals

Pharmaceutical developments walk side by side with health advances to provide new medicines, treatments, and therapies that have increased life quality and extended life expectancy by years. Pharmaceutical manufacturing equipment helps deliver products to a great deal of the population, but there’s a significant share that doesn’t benefit from them yet. Over 2 billion people cannot get the medicines they need, according to the United Nations Industrial Development Organization, and local production might be a way to provide for these people.

Pharmaceuticals

liquid

ci-precision-weight-checking-brochure-pdf

CI-Precision-weight-checking-brochure.pdf

CI Precision (http://www.ciprecision.com) manufacturers world-leading solutions for weight sorting of capsules and tablets for R&amp;D and small-scale production.

Easily and automatically sort by weight or number within a compact benchtop footprint

Save time with sorting rate of up to 75 units per minute

GMP design with quick and easy cleaning, all contact components stainless steel or PEEK

Highly accurate CI Precision balance

Extreme accuracy up to +/- 0.5mg for even more precision

Option of a hopper for larger batches

<span style="font-weight: 400;">For laboratory pharmaceutical R&amp;D work or use in clinical trials, a high-accuracy small-scale benchtop weight sorter is the perfect solution. However, small size should not limit flexibility, and a benchtop machine able to handle a full range of tablet and capsules saves cost and improves efficiency.</span>
<h2>Fully flexible and high accuracy weight sorter scaled for the lab</h2>
<span style="font-weight: 400;">The SADE SP-B40 from CI Precision is a highly accurate, easy to operate and fully flexible solid dosage weight sorter for use in laboratory environments. Designed to be very easy to operate, product is simply loaded into the bowl feeder and then automatically weight-sorted to an accuracy of +/- 1mg. The unit can also be configured to offer accuracy of +/-0.5mg for situations that require even more precision. Like the other members of the SADE family, the SP-B40 can handle tablet sizes up to 20mm x 24mm, and capsules from 5 through to 00 size (larger sizes may be accommodated).</span>

<span style="font-weight: 400;">Offering even more flexibility and value, as well as weight sorting the machine can be quickly and easily configured into quantity sorting mode. This makes it perfect for filling bottles or other containers with the exact number of doses required every time - particularly useful in clinical trial situations. The unit records all operations and can send reports direct to a printer or via a PC interface.</span>

<span style="font-weight: 400;">As well as saving time by eliminating the need for manual sorting and operating at up to 75 units per minute, the SP-B40 is also quick and easy to clean down, and its GMP design means all contact surfaces are either stainless steel or PEEK.</span>

Benchtop weight sorter for tablets &amp; capsules

Sorting is the process of arranging items systematically, using a specified criterion, to categorize and group similar items and identify non-conforming items for removal. The choice of a sorting machine depends on the type of item to sort, the sorting criteria, the number of categories that the items need to be sorted into, sorting speed, and accuracy. Sorting machines can be used in the food industry for sorting and categorizing fruits, vegetables, empty bottles, crates, and other items; other examples include sorting of tablets and capsules by weight for quality control in the pharmaceutical industry.

Sorting

Capsules, being a common and easy-to-produce pharmaceutical dosage form, are gelatin, collagen or cellulose based containers that enclose medicine in solid, paste or liquid forms. Capsules in general contain a single dose of active ingredients and are taken orally. It is vital that the API filled in the capsule production process should not attack the shell and release the content of the capsules. Furthermore, the shell enclosure helps to delay the release of the API into the digestive tract.

Capsules

Tablets are pharmaceutical solid dosage forms containing drug substances. In addition to the active ingredients, tablets contain excipients such as diluents, binders, glidants, and lubricants, that play a different role in tablet formulation. Tablets are commonly made by compression of granules or powder blends but can be shaped by molding. Thus, specialised equipment used in tablet manufacturing and processing is needed.

Tablets

solid

Softgel capsules fast-track the delivery of medication to the bloodstream. Unlike solid pills, they do not need to be broken down by the body before the drugs can be absorbed. Moreover, they are optimal vehicles for oils and fat-soluble formulations that cannot be compressed into tablets.

Softgel capsules

The two-piece capsule is a visual shorthand for all types of medical remedies. Advances in technology have made the production of hard-gelatin capsules a convenient delivery method for drugs and other ingested substances. But the simple solution requires micrometric precision to be manufactured to the proper pharmaceutical standards.

Hard gelatin capsules

The nonproprietary name for HPMC – hydroxypropyl methylcellulose – is such a mouthful that it has two abbreviations. Hypromellose is the other one. The non-ionized material offers a safe alternative to gelatin capsules, especially as most common API and excipients are suitable HPMC capsule ingredients.

HPMC capsules

Sejong Pharmatech is an experienced manufacturer of high quality and innovative pharmaceutical machines.

Scale-up machine that boosts line efficiency and fills 126,000 units per hour

Innovative powertrain design increases component life and reduces downtime for maintenance

Automatic jam removal with no disassembly required

AWC systems automatically rejects incorrect weight as well as faulty capsules

Fully 21 CFR part 11 compliant graphical control and recording system

<span style="font-weight: 400;">For higher production volumes of pharmaceutical capsules, speed, accuracy and reliability of production machinery is vital. For medium volume production lines this combination becomes particularly important, as increased speed should not detract from the highest levels of accuracy and efficiency.</span>
<h2>High performance capsule filler for medium volume production line</h2>
<span style="font-weight: 400;">The Sejong Pharmatech F125 series is a scale-up capsule filling solution with cutting edge features that can operate at up to 126,000 units per hour.</span>

<span style="font-weight: 400;">The F125 has an innovative drive train that has been designed to reduce vibration levels, this results in lower noise and a longer component lifespan. Modular construction means part replacement is straightforward and simple when required.</span>

<span style="font-weight: 400;">Advanced features include a high pressure air system for the automatic clearance of capsule jams. This reduces downtime as there is no need to disassemble the unit.</span>

<span style="font-weight: 400;">For the highest accuracy levels, the F125 uses a 5 stage compression molding system prior to fill. This ensures optimum pressing results. In addition, the automatic weight control system ensures minimal variance from the programmed fill level, and offers automatic rejection of failed fills, as well as imperfect capsule closures or damaged sleeves.</span>

<span style="font-weight: 400;">To suit your exact requirements, the F125 can produce a large variety of doses, filling capsules with powders, tablet and pellets. The F125 can also produce combination capsules containing mixed dosage types.The control system is fully 21CFR part 11 compliant, with graphical touchscreen control for ease of operation and monitoring of performance.</span>

Scale up capsule filler

Process

The two halves of a capsule shell are separately filled with your selected material before they are then pressed against one another and closed. Automatic capsule fillers orientate the shells in the precise position, fill them with your specified formula a join the ends. Capsules are then de-dusted and polished by micro brushes before they are ready for packaging.

Capsule fillers

Continuous

Dosing systems include hoppers, feeders, filling machines, and checkweighers. The selection of suitable dosing equipment depends on the need to dose by quantity, the size of each dose, and the desired dosing rate. The physical form of the material, health and safety requirements and the container to be filled are also important considerations. Dosing systems are used for filling containers in the pharmaceutical industry and for accurate dosing of ingredients in the food and chemical industries. Discuss your dosing challenge with us to receive advice on the most suitable solution for your application.

Capsule manufacturing spans a series of stages until your finished products can be shipped out. Dosage systems and sorters ensure that the capsule filler machine is fed with the right formula at all times. In the case of gel-filled capsules, you would need gelatin melters that keep the mixture ready for use. Depending on their type, capsules are then dried, de-dusted, and polished using dedicated encapsulation equipment and conveyed to a final weight and quality check. Lastly, you may opt for a sleeve label to seal the package and safeguard its integrity to consumers.

Industrial filling equipment solutions are used to package a measured mass or volume of a product, at the end of a production line, into a packaging container suitable for the product. The choice of filling system or filling line depends on the physical state of the product, the packaging container of choice, the desired mass or volume per container, the required production volume, and considerations of sterilization and safety.

virto-catologue-pdf

Virto-catologue.pdf

virto_-t-line_v8-pdf

Virto_-T-LINE_v8.pdf

Cocoa minus its fats makes cocoa powder. Deriving this culinary element follows a careful process of roasting and winnowing cocoa beans before the nibs are ground, generating a liquor. The butter that results from melting fats is removed to leave the ingredient that defines recipes from brownies to a Frostbite cocktail.

Cocoa powder

Flour processing technology has changed drastically since the days of the millstone pulled by a mule. But demand for more refined flour means that the production process is now slower than with more rudimentary techniques. When mixed with water, protein in wheat flour form an elastic gluten structure, giving bakery products their irresistible fluffiness.

Flour

Baking powder is perhaps the best-known secret of baking. The leavening agent forms bubbles in dough and batter to give muffins, cakes, and no-yeast pizza their tempting lift. First developed in the 19th century, baking powder production turned baking into the home activity we know today.

Baking powder

<span style="font-weight: 400;">Any coffee-drinker can agree that a cup of coffee in the morning can brighten up their day. As the most convenient way of making coffee, many people choose to make coffee at home. Whether you want to make Moka coffee or filtered coffee, you need ground coffee that is grind appropriately for the coffee brewing method of your choice. These ground coffee are manufactured by roasting and grinding processes. </span>

Ground coffee

Filter coffee

Do you know that the famous classical music composer and pianist Ludwig van Beethoven insisted on drinking a cup of coffee made from exactly 60 pieces of coffee beans? Currently, around 50% of the world’s green coffee beans undergo processing through instant coffee manufacturing equipment to produce instant coffee. The process requires roasting, grinding, brewing, and heating to obtain the extract; the coffee extract will either go through a spray drying process or a freeze-drying process.

Instant coffee

Basically, to make milk powder, you need to remove the water content from the liquid milk and turn it into powder. How to do it? After pasteurizing and homogenizing the milk, milk’s water content is removed through filtration, evaporation, and drying. You have then to cool and sieve it before filling the containers. Here's how you get milk powder.

Milk powder

To produce condensed milk, you need to remove a large portion of the water content from the milk. Usually, you add sugar to it to create a sweet flavor. First, milk is standardized and pasteurized. Then, it goes through an evaporation process to remove the excess water content while sugar is added. After that, the mixture undergoes homogenization. The condensed milk is cooled and crystallized before being ready for packaging.

Condensed milk

API making equipment must observe rigorous quality standards across the entire manufacturing process. The pharmacodynamic properties of active pharmaceutical ingredients make them highly sensitive to their environment, making API production a tightly regulated field.

Active pharmaceutical ingredients (API)

As traced back to the first half of the 19th century, attempts at synthetic rubber production were simply to reproduce the original material due to the rubber shortage following World War II. Synthetic rubber production processes differentiate between producing the rubber, which can be done via solution polymerization and emulsion polymerization and creating the final product with the help of techniques such as molding and vulcanization.

Synthetic rubber

The classification of sunflower seeds changes according to the pattern of its shell or hull. If the shell is solid black, it is an oilseed sunflower. With these, you produce sunflower oil. If the shell is striped, it is a non-oil sunflower seed or confectionery sunflower seed. These usually become snack food products. Whether to make them as snacks or oil, processing sunflower seeds include steps like drying, screening and cleaning, grading, roasting and de-hulling, flavoring, grinding, pressing, refining, and packing.

Sunflower seeds

With operations starting nearly 70 years ago, Cuccolini (Virto Group) (https://www.virtogroup.com) is one of Europe’s largest manufacturers of screening and separation equipment producing up to 3,500 vibrating sieves a year for more than 65 different industries.

5 times more capacity per m2 of mesh than traditional alternatives

High efficiency screening down to as little as 20 microns

Full ATEX and FDA certification available

Quick replacement of sieving deck thanks to deck lift system

Specifically designed for gentle handling of high volumes of all delicate powders and granules

For the classification of delicate granular material, screen tumblers make an excellent alternative where high throughput is still required with gentle handling. This is important to many processes in the chemicals, pharmaceuticals and food industries, where traditional vibratory sieves and graders are too harsh for delicate materials.


<h2>High capacity tumbler for delicate, dry materials</h2>
The Virto VTU 2400 is a purpose-designed high capacity tumbler sieve capable of achieving up to 95% efficiency for particle sizes as small as 20 microns.

Especially suitable for multi-stage separation of fine, lightweight and difficult to screen products, the VTU 2400 uses three-dimensional movement for class-leading performance with powders and granules. The exact nature of the movement can be adjusted to suit your requirements.

The tumbler screen can use meshes down to 20 microns, can be supplied with anti-clogging systems composed of FDA-certified rubber spheres or ultrasound systems to your specification.

All product contact parts are constructed of AISI 304 stainless steel, and ATEX certification and full FDA conformity is available on request.

The VTU 2400 is available with 1 to 5 sieving decks, and offers a total mesh size of 4.5m2 for maximum productivity.

Solidly built for enhanced reliability, the VTU 2400 tumbler sieve is energy-efficient and quiet in operation, making it suitable for a wide range of applications.

Tumbler sieve for classifying and dedusting granular materials

Dedusting can be accomplished by pneumatic means or by dry screening. Considerations for choosing a suitable deduster include the particle size distribution of the pellets or granules, the desired production volume, and the resistance of aggregates to mechanical agitation. Dedusters are used in the food industry for cleaning grains and nuts and in the mineral industry for the separation of dust from granular mineral products. Dedusting is also necessary to clean containers and bottles before filling or keeping dust out of the production machine.

Dedusters

Food

Mineral

Evaporation equipment is used to reduce or remove the moisture content of a mixture. Considerations for choosing suitable evaporation equipment include the moisture content in the mixture, the boiling point of the solvent, heat sensitivity of the product, and the amount of material to be processed. Evaporators are used for applications such as obtaining fruit and vegetable concentrates in the food industry, concentrating aromas and herbal extracts in the cosmetics industry, and to isolate active ingredients in the pharmaceutical industry.

Evaporating

Filtration equipment separates solid matter from liquid by using a filter medium. The filter allows only the fluid to pass through but retains the solid matter. The choice of filtration equipment depends on the particle size, the consistency of the mixture, and the nature of your product.

Separation process to separate components of a liquid mixture, for recovering dissolved solids from liquids. Choice of a suitable technology depends on the identification of the key physical or chemical property, such as size, mass, density, or boiling point, which sets the product of interest apart from the rest of the components. Separation technology are widely used in the pharmaceutical and chemical industries for the isolation of active ingredients and high purity chemicals.

Separation

Sieving machines are available in various designs such as linear sieves, tumbler sieves, and vibrating sieves each employing a different sieving action. The choice of a suitable sieving machine depends on the desired particle size distribution, required amplitude and frequency of vibrations, and the physical state of the mixture. Sieving machines are used for removing dust from granular products and for grading grains. They are also used for the classification of granular material and the separation of solids from a slurry mix in the food processing industries.

Sieving

With over one-third of the population consuming it on a daily basis with different forms, coffee is definitely one of the most popular processed beverages around the world. Not only serving as drinks, but coffee is also often regarded as a culture. Coffee manufacturing is a knowledge-intensive industry. Coffee beans from different regions will reveal different tastes, while the level of caffeine could also be different. When it comes to coffee bean processing, the range of roasts varies from light golden brown all the way to dark. The way of tasting coffee differs between countries, habits, and tools to use.

Coffee

Our food chain starts in the soil, growing crops and livestock. But between the fields and the stores, there is a line of industrial food processing equipment. Processes may be as minimalistic as cleaning fruit and as complex as homogenizing milk alternatives made from pressed legumes. In each case, processing technology is an important link in the food production chain.

Pharmaceutical powders provide longer shelf life and better stability than liquid dosage forms. But the processing of pharmaceutical powders is crucial for growing segments besides pharmacy. Functional foods and cosmetics formulated with active ingredients depend on powdered forms to fulfill their promises.

Pharmaceutical powder

The building blocks of matter have driven the imagination of philosophers, scientists, and artists for millennia. But, for manufacturers, these elements have a more concrete existence as powders. Powder processing technology conditions these primary materials to create a vast range of products, from chemicals and foods to pharmaceuticals and ceramics.

Powder

bossar_retort-br-series-pdf

Bossar_Retort-BR-Series.pdf

Liquid soup

It all begins with tons of tomato paste that is mixed and heated together with sugar, vinegar, and spices in a cooking kettle. After cooking, any remaining fibers and particles are filtered out. Once it reaches the right viscosity, your tomato ketchup production process is finished and ready for packaging and transport.

Ketchup

Salad dressing has found its way onto dinner plates for millennia as a quick way to liven up leafy dishes. Experimentation with oil, vinegar, wine, salt, and other ingredients developed into the broad selection of dressings we enjoy today. Through a process of emulsifying the basic formula, adding additional elements, and then bottling and labeling the final mixture, consumers have easy access to reliable tastes on demand.

Salad dressing

Tomato sauce is a popular ingredient for adding a sweet, slightly acidic touch of flavor. Sauce production involves cooking the tomatoes, straining out the seeds and stems, and then further cooking to the desired consistency. Tomato sauce making equipment is used in industrial production to speed up the various preparation steps while maintaining the quality of the sauce.

Tomato sauce

First commercially sold baby food was created by Henri Nestlé when he combined cow milk with sugar and grains. Baby food industry has since grown to offer everything from whole wheat infant cereals to ramen-flavored baby food. From infant cereal to fruit puree, choosing the baby food processing equipment is related to the type of baby food you want to make.

Baby Food

Broth

In 1922, the first canned wet pet food made of horse meat hit the US market. Due to the product’s popularity, farmers started breeding horses to supply the demand for wet pet food.
Nowadays, wet pet food is no longer made of horse meat, but of chicken, fish, beef and pork and also vegetables, grains and added vitamins and minerals. Wet pet food processing involves different steps such as weighing, grinding, mixing, packaging, and sterilization.

Wet pet food

Bossar designs and manufactures a wide range of HFFS packaging machines featured full-servo control system.

Easy to clean and sanitize

Guaranteed hermetic seal thanks to perfect temperature control

Optional N2 or steam injection

Optional valve insertion

A wide variety of products that were previously canned are now able to be more economically packaged in retort pouches. These specialised plastic film and metal foil laminates are ideal for food use. Traditional premade pouch filling machines are not suitable for hygienic operations, and a dedicated retort pouch filling solution that can seal to withstand the high pressures of the autoclave is needed.


<h2>Food pouch packaging machine with sanitary design</h2>
The Bossar BR Retort series is a range of machines designed specifically for hygienic filling of premade retort pouches for food products. They are perfect for product lines such as soup, tuna, chicken, sauces, prepared meals and pasta, as well as pharmaceutical applications.

Constructed from AISI 304 stainless steel, the BR series is easy to clean and sanitize. In addition, all parts that are product contacting are made from AISI 316L stainless steel. Optional residual oxygen removal systems can be specified, either N2 or steam injection, to meet your exact requirements.

The Bossar-designed high-pressure sealing system has been designed to give a perfect seal every time, and offers temperature control of +/- 1 degree to guarantee a hermetic seal on a wide range of pouch types.

A robust walking beam transport method ensures reliability and accuracy while allowing throughput of up to 180 pouches per minute. The BR series can seal flat or stand-up pouches ranging from 60mm x 80mm up to 330mm x 300mm. Maximum fill volume can be up to 2,000cc.

&nbsp;

Retort Pouch Packaging Machine

Packaging

An autoclave is a hermetic container that kills microorganisms such as bacteria, viruses, and spores by using steam under pressure. The steam is pumped at a higher pressure than normal atmospheric pressure to reach a temperature of 121–140 °C. Autoclaves can vary in size, shape, and functionality depending on the product to be sterilized.

Industrial autoclaves

A pouch is a small bag made from a single layer or a multi-layered laminate of paper, foil, and plastic films. The choice of pouch packaging equipment depends on the type of pouch, physical form of the product to be packaged, desired dimensions or volume of the pouch, and whether pouch forming is required or pre-formed pouches will be used. Specialized equipment may be required for the inclusion of a dispensing spout in the pouch or to make the pouch retortable.

Pouch packing equipment

The process of forming allows you to shape your products homogeneously. Forming machines are fed the manufactured material in bulk and cut it down to specification, so the process takes place between formulation of the mass and the packaging of the final item.

A special class of this equipment – Form, Fill, and Seal Machines (FFS) – creates bags and pouches from flat material such as plastic sheets, fills them with your designated product, and seals them.

Forming

Packaging preserves and protects a product from damage, spoilage, and contamination while it makes its way from the production line to the consumer or further production. Choosing the best packaging solution depends on the nature of the product, its end-use, and your production process.

Packing

Fruit pulp is a mass of pressed fresh fruit not meant for immediate consumption. Production of fruit pulp avoids wasting food, preserves the flavors and nutrient value of the fruit product. Processed fruit pulp is an ingredient in beverages, sauces, baby foods, jellies, smoothies and bakery products.

Tradition and manufacturing procedures dictate the distinction between fruit juice, puree, and pulp. Still, naming and labeling are complex depending on regulations, type of fruit, texture and consistency, preservation methods, as well as sugar or solid content (measured in Degrees Brix). Depending on your desired output, there are various fruit pulper machines for various stages of production that make the process quicker and more efficient.

Fruit pulp

A sauce is a liquid, cream or semi-liquid substance served with, or used in preparing food. It adds flavour, moisture and visual appeal to a dish. Sauces can be used for sweet and savoury dishes. Their texture can range from smooth liquids, like mayonnaise and dressings to highly viscous and even grainy or chunky dips like pestos and salsas. Sauces are essential in all cuisines but also vary in taste worldwide.

Sauce

Industrially manufactured soups gained traction in the 19th century when canning was invented and they have been warming us ever since. Whether it’s a classic ready-to-eat canned soup, condensed soup or a dry soup mix, soup manufacturing equipment for mixing, cooking, boiling, or sterilizing caters to every manufacturer’s production requirements.

Soup

ft-system_inspection-machine-for-flat-bottle-caps_qt730-va_catalogue-pdf

FT-System_Inspection-machine-for-flat-bottle-caps_QT730-VA_catalogue.pdf

To ensure product quality and freshness in the drink industry, capping is a very important step. Sometimes during the capping phase, products are rejected due to defective caps causing delay in the production line. To avoid jams along the line, it’s helpful to inspect bottle caps with a machine before they enter the capping process and not when they are being capped.


<h2>Artificial vision system to inspect cap quality before capping phase</h2>
QT730-VA is an inspection system for cap quality manufactured by FTsystem using artificial vision technology. The system is available in different configurations based on the caps to be checked. The artificial vision provides a high-level quality control thanks to industrial cameras that, with the help of direct analysis, gathers information about cap defects. In QT730, caps are introduced and positioned in the star wheel via the integrated chute. As the wheel rotates, caps pass one by one under the camera that analyses them. The camera is able to detect for example overturned caps, ovalization, deformation, security ring or sealing ring defect/absence and contamination. Based on the caps and the inspection, in the standard configuration more cameras could be implemented. This particular version is recommended for flat caps, for caps that have an irregular upper surface like sport caps and for shaped caps.

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Enrich the LAB cultivation medium with magnesium and manganese

Preserve cell viability with cryoprotectants when using probiotics processing technology

Higher pH stability makes Bifidobacterium more resistant to post-acidification

Ensure probiotic concentrations in end products meet claim requirements

Processing steps involved in probiotics making

Bioreactor systems

Capsule fillers

Freeze dryers

High-shear mixers

Single use systems

Bioreactor systems

Capsule fillers

Freeze dryers

High-shear mixers

Single use systems

Bioreactor systems

Capsule fillers

Freeze dryers

High-shear mixers

Single use systems

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