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Cannabinoids Packing Equipment

Cannabis seeds

Gummies make everything more colorful. The squishy droplets make a tasty and practical carrier of special ingredients such as CBD oil. Chewing the gum increases the bioavailability of the substance as opposed to vaping. But before the cannabidiol can take effect, it must first be processed through a line of CBD gummy equipment.

CBD gummies

While still forbidden in many countries, there's plenty of room for the use of cannabidiol, or CBD. It’s the second most present active ingredient of the cannabis plant and, no, it won’t get anybody high. What it does, really, once it’s out of the CBD oil processing equipment, is to provide many well-being and health benefits. They go from treating depression and anxiety to relieving pain and unmanageable diseases' symptoms.

CBD oil

Softgel capsules fast-track the delivery of medication to the bloodstream. Unlike solid pills, they do not need to be broken down by the body before the drugs can be absorbed. Moreover, they are optimal vehicles for oils and fat-soluble formulations that cannot be compressed into tablets.

Softgel capsules

The cannabis industry is one of the fastest growing in the world with a revenue of $20.47 billion in 2020 which is expected to soar up to $197.74 billion in 2028. The famous cannabis substance that causes marijuana's psychological effects is THC and it was first isolated in 1964. There are two methods of extracting THC from cannabis: solvent-based and non-solvent extraction. Each technique requires different THC oil extraction equipment.

iwk_cartoner_vi5_en_2014_sept1-pdf

IWK_Cartoner_Vi5_EN_2014_sept1.pdf

After being used to contain the blood of martyrs after death or to store the anointing oil of French monarchs, today ampoules are the first choice in packaging injectables. You create ampoules by melting the glass tube into the desired shape and seal them at the neck by melting the top of the glass tube. The only way for you to extract the contents from an ampoule is by breaking the glass at its breaking point, making it perfect for single dose applications only.

Ampoules

Every minute, your skin loses between 30,000 and 40,000 dead skin cells. This means losing millions of cells every day, which makes your skin look less glowing. Being a moisturizing agent, body lotion has the power to hydrate your skin and  give the glow back to it. Production involves water and oil phases, which you then mix with an emulsifier and blend until homogeneous. Preservatives are essential for any solution containing water for the prevention of microbial growth.

Body lotion

Star-shaped, lavender-scented, yellow, green, in a dispenser, today’s hand soap comes in a variety of shapes, fragrances, and colors. But whatever type of soap you choose for your good hand-washing habits, the basis of all soap making is mixing animal fats or vegetable oils with an alkali - in this case, a strong base - in a kettle to produce a chemical reaction called saponification.

Hand soap

Pharmaceutical cartridges are glass containers of cylindrical shape, suitable for liquid or solid pharmaceutical dosage forms. Generally, these are designed for a specific apparatus such as pre-filled syringes and autoinjectors. Drugs that can be placed in cartridges using a pharmaceutical cartridge filling equipment include insulin, dental anesthesia, and other emergency drugs for allergies.

Pharmaceutical cartridges

A pre-filled syringe or PFS is a single-dose disposable syringe that is supplied loaded with the substance to be injected. By using a pre-filled syringe filling machine, you can have excellent dosage accuracy due to the exact filling of medications. During administration, safety from potential contaminants is also ensured as they are directly injected after opening. To further minimize the risk of contamination, pre-filled syringes are often filled and sealed in a sterile environment using stainless steel equipment.

Pre-filled Syringes

Surgical instruments still involve a significant degree of manual craftsmanship to manufacture. But advances in surgical instruments technology today intertwine with expert handiwork to produce precise tools that make the difference between life and death.

Surgical instruments

Flexible cartoner for a wide variety of product types

Fully servo-driven for increased reliability and lower maintenance cost

Extremely quick product changeover minimises downtime

Handles any carton blank conforming to DIN 53121, or pre-glued to DIN 55222

Simple to operate, access and clean

When thinking about blister packaging equipment, pharmaceutical products such as capsules or tablets are the first things that come to mind. Blister packs are used to protect pharmaceutical products from humidity and contamination and to extend their shelf life. However, they are also used for food items or consumer goods such as toys. There are two main methods and packaging solutions on which blister machines are based. Thermoforming heats PVC sheets in batches which are then pressed into blister machines to give them the desired shape. Cold forming doesn’t involve any heat and uses aluminum-based laminate film instead of PVC film.

Blister Packaging Equipment

A pouch is a small bag made from a single layer or a multi-layered laminate of paper, foil, and plastic films. The choice of pouch packaging equipment depends on the type of pouch, physical form of the product to be packaged, desired dimensions or volume of the pouch, and whether pouch forming is required or pre-formed pouches will be used. Specialized equipment may be required for the inclusion of a dispensing spout in the pouch or to make the pouch retortable.

Pouch packing equipment

Cosmetic

Pharmaceutical

Industrial Packaging Equipment

<span style="font-weight: 400">At last, you reached the final stage of processing your product - welcome to the packing world! Packing preserves and protects a product from damage, spoilage, and contamination while it makes its way from the production line to the consumer or further production. Depending on which industry your products belong to, the type of primary packaging equipment can change drastically. You need to pay careful attention to products with </span><span style="font-weight: 400">chemicals or hazardous substances since they can be potentially dangerous to human health. </span>

Packing

Connect directly with world leading manufacturers of industrial packaging equipment and find technology to build or improve your production line.

Packing - Making.com

Industrial Packaging Equipment - Making.com

Biopharmaceuticals are drugs in which the active substance is manufactured or extracted from biological origin materials. They are usually produced in bioreactors by plant cells, microbial cells, yeast cultures, or mammalian cells. Also known as biomanufacturing, they are used to either treat or diagnose and prevent a patient’s medical condition or disease. Biopharmaceuticals are typically complex macromolecules administered by injection or infusions, and examples include vaccines, serums, and insulin.

Biopharmaceuticals

Cannabinoids are natural compounds obtained from the Cannabis sativa plant. Delta-9-tetrahydrocannabinol or THC is a psychotropic substance. Cannabidiol, or CBD, is non-psychotropic and often used for nutraceutical purposes. Cannabinoid equipment extracts THC and CBD from the plant and prepares the substance for formulations that treat pain, nausea, anxiety, and inflammations. Cannabinoids are processed in various forms, including creams, capsules, and oils.

Cannabinoids

According to a legend, Cleopatra soaked her sails in her perfume so that Mark Antony could smell her ships before they arrived. This is to say that, from soaps and shampoos to perfumes, conditioners and pomades, cosmetics have always been highly valued and used for their properties of aesthetic enhancement. Cosmetics are a broad class of topical agents applied for various purposes such as cleansing, protecting, beautifying, or otherwise altering your appearance. As a result, a wide array of processing equipment is used in the cosmetics industry.

Cosmetics

The topical route is a convenient route for the self-administration of drugs. But turning a pharmaceutical formulation into an easy-to-use cream involves specialized cream manufacturing equipment. Topical dosage forms are essentially an emulsion of oil and water.  But the ratios can be changed to process it into lotions, ointments, and gels.

Cream

Parenteral preparations refer to drugs using non-oral means of administration. Injectables, such as needles and syringes, are used to deliver a drug into the systemic circulation directly in the veins, muscles, under the skin, or in the tissue.

These parenteral formulations are pharmaceutical dosage forms that have strict regulations on being sterile, pyrogen-free, and free from visible particulate matter including reconstituted sterile powders. Solutions, suspensions, emulsions, and gels with APIs intended for administration by injection are usually supplied in vials, ampoules, pre-filled syringes, or pens to facilitate ease of use.

Injectables

Although not all women use makeup every day, almost all of them own at least one makeup product, be it lipstick or face powder. Most makeup products share the same basic ingredients of waxes, oils, and fillers with pigments like iron oxide used for colors and shades. Makeup manufacturing equipment includes pulverizers, mixers, and mechanical press machines to produce cosmetic products in different forms such as powder, liquid, or mousse.

Makeup

Pharmaceutical developments walk side by side with health advances to provide new medicines, treatments, and therapies that have increased life quality and extended life expectancy by years. Pharmaceutical manufacturing equipment helps deliver products to a great deal of the population, but there’s a significant share that doesn’t benefit from them yet. Over 2 billion people cannot get the medicines they need, according to the United Nations Industrial Development Organization, and local production might be a way to provide for these people.

Pharmaceuticals

Packaging

R&amp;D

Batch

Cartoning involves erecting a folded carton, filling it with the product, closing the flaps, or applying a lid and sealing with glue or adhesive tape. Choosing a cartoning solution involves, considering the type of primary packaging, the production volume, the size and count of the product in a carton, and the desired level of automation.

Cartoning

Thermoforming

solid

Many pharmaceutical and cosmetic products are sold in protective and decorative cartons. An automatic vertical cartoner can greatly increase packing

Vertical cartoner for pharmaceutical applications - Making.com

https://making-tst.imgix.net/2017/09/VI-51-1.jpg

The marketplace for finding innovative production technology

Making.com

iwk_cartoner_vc5_en-pdf

IWK_Cartoner_VC5_EN.pdf

The most significant decision when making ointments is likely to be the choice between automatic or semi-automatic processes for it. This impacts on individual phases of the ointment cream manufacturing process - the water phase and oil phase.

Ointment

During crime scene investigations in any movie, you've probably seen forensic scientists collecting evidence and biological samples in small containers. Here, these are the vials, used to store medicines, especially in liquid form, or laboratory samples. Often made of glass or plastic, vials can be labeled as single-dose vials or sterilized and reused more than once. They are also available with various closure systems depending on the material and storage requirements.

Vials

A missing tooth can wipe a smile off your face. But high-precision engineering is filling the gap with dental implants manufacturing equipment. Advanced technology produces safe implants from biomaterials that fuse with the jawbone.

Dental implants

Flexible higher-speed cartoner for a wide variety of pharmaceutical products

Servo drive improves reliability and requires less maintenance

Touch screen control, central height adjust and “click in” carton buckets mean very quick product changeover

Handles all carton blanks conforming to DIN 53121, and pre-glued blanks to DIN 55222

Ergonomic design is to access, clean and maintain

Process

Continuous

Many pharmaceutical products are packed in protective and decorative cartons. Using an automatic vertical cartoner increases the efficiency of the packing

High capacity cartoner for pharmaceutical applications - Making.com

https://making-tst.imgix.net/2017/09/M2014_Kartonierer_VC5_06_without-IWK-3-1.jpg

iwk_cartoners_sc_si_4-6-8_en_2014-pdf

IWK_Cartoners_SC_SI_4-6-8_EN_2014.pdf

You can make emulsions by combining two immiscible liquids (oil and water, for example) in a suspension through the use of force. The use of emulsifiers is necessary to keep this mixture stable and permanent.

Emulsions

After shaving, anti-aging, with organic ingredients, for the feet... Lotions are many. They compose the skincare world, which has been growing in recent years. More consumers look for the benefits of products that promise to enhance well-being and self-care. Whether you want to help prevent wrinkles, provide vitamins or just hydrate your consumers’ skin, get your formula and select lotion making equipment to get started.

Lotion

Designed specifically for pharmaceutical and cosmetics applications

Full range of options to suit your exact requirements

Servo drive technology and remote servicing for increased uptime and reduced maintenance

Product identification, quality checking and full track and trace systems available

Most pharmaceutical and cosmetics products are packed in cardboard cartons for protection and branding. The use of an automatic horizontal cartoner

Horizontal cartoner for pharma and cosmetics - Making.com

https://making-tst.imgix.net/2017/09/SI-4-1.jpg

iwk_cartoner_sc5-en-pdf

IWK_Cartoner_SC5-EN.pdf

Sunscreen is an emulsion which can be either oil-in-water or water-in-oil. To create it, you must prepare an oil phase and a water phase separately, then mix and heat them. Homogenization is a key process to guarantee that the product will have the right consistency. When manufacturing sunscreen, give special attention to protection against UV filters.

Sunscreen

It's been estimated that we spend an average of 3,000 hours brushing our teeth. In fact, in our daily routine, toothpaste is something we use at least twice a day. Making toothpaste is a very straightforward process; just mix together water, abrasives, humectants, thickening and foaming agents, sweeteners, and flavors in the right amounts until you get a paste. Once you have added the colors, you can fill a tube with your colorful toothpaste and seal it before being shipped to stores.

Toothpaste

A case is a secondary packaging box that contains a number of identical product items. The items may be arranged in a single layer or stacked in multiple layers separated by trays. A case packer erects the foldable case fills it with product items in the desired configuration and applies the lid before the case is sealed. Case packer selection depends on the configuration of items in the case, the desired level of automation, and the primary packaging of the product item.

Case packers

A large number of cosmetic and pharmaceutical products are packed in cardboard cartons for protection and branding. For medium-scale production lines, the

Pharmaceutical and cosmetic industry products cartoner - Making.com

https://making-tst.imgix.net/2017/09/SC-5.jpg

A dishwasher tablet is an essential detergent. It consists of a pressed mixture of sodium and potassium salts, surfactant, fragrance, and other filler agents, mixed with the help of tablet making machines. The products’ use in America and Europe is high, unlike in the Asian continent, where the price limits its usage. Its global market size will reach $990 million in 2026 from $475.6million in 2019, according to Grand View Research forecasts.

Dishwasher tablets

High capacity continuous cartoner, specifically for cosmetic and pharmaceuticals

Full range of options to suit your exact production requirements

Modular concept for easy retro-fit and upgrade

For high capacity production of cosmetics and pharmaceuticals a high speed cartoner is vital for line efficiency. Automatic cartoners take carton blanks

Automatic cartoner for applications in pharma and cosmetics - Making.com

https://making-tst.imgix.net/2017/09/SC4-Machine-Frontside.jpg

Highest performance for large scale FMCG lines and pharmaceuticals

Lowered product chain for direct use with TFS 80-6/8 high-end tube filling machine

Full product identification using track and trace technology

Designed for high efficiency with minimal downtime

Cartoners take carton blanks which are formed and sealed, allowing the product to be inserted from the side, and then closing and passing on for final

High-capacity horizontal cartoner for pharma and cosmetics appliances - Making.com

https://making-tst.imgix.net/2017/09/SC-31.jpg

romaco-liquid-filling-brochure-pdf

Romaco-liquid-filling-brochure.pdf

romaco-macofar-lf200-datasheet-pdf

Romaco-Macofar-LF200-datasheet.pdf

The word parenteral comes from Greek and means outside the intestine (para=outside and enteron=intestine). In fact, when it comes to parenterals, we are referring to those dosage forms that are administered directly into the bloodstream using a hypodermic needle, avoiding going through the gastrointestinal tract. Using parenteral filling equipment, parenteral solutions are placed in containers such as vials, syringes, or ampoules.

Parenterals

Chewable tablets are suitable for patients who have difficulty swallowing. Chewable tablet formulation masks the natural flavors of pharma drugs and alters their aftertaste. But besides the taste, chewable tablets favor the bioavailability of pharmaceutical ingredients.

Chewable tablets

The fizz of effervescent tablets is commonly associated with a vitamin C boost. But the soluble pill is an excellent drug delivery method for pediatric and geriatric patients. Sometimes referred to as carbon tablets, manufacturing effervescent tablets binds biocarbonate and citric acid that produce the smooth hiss as they dissolve in liquid.

Effervescent tablets

When taking a tablet, it is usually the job of our stomach to break down the medication to make it ready to be absorbed into the bloodstream. However, some drugs are not meant to be dissolved in the stomach because the acidic pH of the stomach can disintegrate the drug, making it no longer effective. Using tablet coating equipment that applies a polymer barrier to the tablet makes it possible to protect it from stomach acidity.

Enteric Coated Tablets

Microtablets range between 1 and 4 millimeters, making the dosage form an excellent delivery system in polypharmacy. The size of the products makes them easier pills to swallow, but microtablets production brings a unique set of complexities.

Microtablets

Multilayer tablets are a popular fixed-dose combination (FDC) offering a range of release profiles for effective drug delivery. Multilayer tablet technology solves challenges to API consistency, allowing manufacturers to develop formulations from incompatible ingredients while optimizing the release profile for immediate release and controlled release.

Multi-layer tablets

The wave of liquid soaps and detergents in the 1950s revolutionized home and personal care. Cheap and convenient, these off-the-shelf products fit perfectly into the lifestyle of the time. A few decades later, though, plastic waste put the sustainability of hygiene products into question. Refill tablet production technology answers that by eliminating single-use plastic. Instead of picking up a new bottle every time, end-users complete the formulation process in a multi-use container and with a simple instruction: just add water.

Refill tablets

It is strange how two tablets can belong to the same but at the same time to a different category depending on how the tablet itself is classified. For example, chewable tablets and effervescent tablets have two different routes of administration but both belong to the category of uncoated tablets. Uncoated tablets are prepared by compression of granules in which no coating is added after compression. They may be single-layer or multi-layer tablets.

Uncoated tablets

There are slight differences between human and animal pharmaceuticals, but that dissimilarity is enough to create new production challenges. Veterinary tablets formulation reflects the diversity of enzymes that different species use to break down substances. Although the methods involved are comparable to human drug manufacturing, equipment and processes need to adapt to a wider dosage variability in veterinary tablets.

Veterinary tablets

The two-piece capsule is a visual shorthand for all types of medical remedies. Advances in technology have made the production of hard-gelatin capsules a convenient delivery method for drugs and other ingested substances. But the simple solution requires micrometric precision to be manufactured to the proper pharmaceutical standards.

Hard gelatin capsules

The nonproprietary name for HPMC – hydroxypropyl methylcellulose – is such a mouthful that it has two abbreviations. Hypromellose is the other one. The non-ionized material offers a safe alternative to gelatin capsules, especially as most common API and excipients are suitable HPMC capsule ingredients.

HPMC capsules

API making equipment must observe rigorous quality control standards across the entire manufacturing process. The pharmacodynamic properties of active pharmaceutical ingredients API make them highly sensitive to their environment, making API manufacturing and production a tightly regulated field.

Active pharmaceutical ingredients (API)

The click and puff of inhalers is a universal signal for respiratory conditions. Inhalers quickly grew into preferred drug delivery systems for asthma and COPD. Dry inhaler powder formulation produces a more stable drug than liquid dosage forms. Moreover, inhaler ingredients are more resistant to bacterial growth.

Dry inhaler powder

Output of up to 12,000 units per hour

Positive bottle transport system

Fast product change-over

Excellent Overall Equipment Efficiency and Low cost

 Low operating costs

Aseptic filling equipment is crucial for sensitive products, as they need to be filled into their primary packaging in an environment free from contamination caused by harmful bacteria, viruses, or other microorganisms. Choosing an aseptic filling solution requires consideration of the physical form of the product, the type of primary packaging, the volume to be dosed per package, and the production speed. Aseptic fillers are widely used for cleaning, filling, and sealing pre-sterilized vials, cartridges, ampoules, and syringes in the pharmaceutical industry. Aseptic filling is also used in the food industry to process for example, dairy products that need harmful bacteria's minimized, or ensure shelf-stable products that do not require refrigeration. In these industries, aseptic equipment is integrated into the production line for maximum isolation and sterilization. And, can either be configured as an automated or manual process, depending on standards that the products require.

Aseptic filling equipment

Bottle filling equipment entails transferring your products to a bottle which involves inspecting the material, and then conveyors feed it into the machine which then pours it into the vessels using volumetric technology and nozzles before capping them. Bottle filing varies not only in product type but in the size, shape, and material of the container too. Depending on your operation, filling systems may adopt in-line or rotary methods before transferring the bottles to the next stage of processing.

Bottle filling equipment

Liquid

Eating is more than just nutrition, but we have found ways to increase the nourishing power of our foods. Nutraceuticals manufacturing, from vitamin C powder and probiotics to omega 3 oil, is a concentration of natural ingredients and health supplements that complement our diets. While dietary supplements are not quite haute cuisine, the process of extraction and purification is no less a blend of science and art.

Nutraceuticals

Dosing systems are a line of hoppers, feeders, filling machines, and checkweighers that operate in sync to dispense materials accurately. Dosing is an essential feature of the packaging process, whether you’re filling shampoo bottles or tea bags. But dosing equipment is critical for formulations, too, particularly in the pharmaceutical and chemical industries. Imprecise dosing may cause quality degradation in the best-case scenario. In the worst scenario, it creates serious health risks.

Dosing

Filling lines are used extensively in all industries, such as food, pharmaceutical, chemical, and cosmetics, to accurately package different products into a container suitable for that product. Although the filling process is at the very end of the production line, it is no less important than the earlier steps. Last but not least, the idiom that dates back to 1382 when John Wyclif wrote the firste the laste, and the laste the firste, indicates just that the last things on a list are just as valuable as the previous ones. In this case, this idiom fits perfectly.

Filling

liquid

The Romaco Macofar LF 200 series are an efficient solution for the filling of liquids and are perfectly adjusted to the increasing market requirements.

Fill liquid pharmaceutical, nutraceutical and cosmetic products in ampoules and bottles with volumes ranging from 2 to 500ml and with maximum speed of

High-speed small volume liquid filler - Making.com

https://making-tst.imgix.net/2014/12/Macofar-LF-200.jpg

romaco-macofar-lvi-datasheet-pdf

Romaco-Macofar-LVI-datasheet.pdf

Output of up to 12000 vials per hour

Easy cleaning and maintenance

Quick, toolless changeover

Low operating costs

The Romaco Macofar LVI can be equipped with volumetric syringes or peristaltic pumps for filling liquids into glass or plastic containers of any shape.

These intermittent motion monobloc machines are designed for filling various liquids into glass or plastic containers with an output of up to 12000 vials

Cannabinoids Packing Equipment

Which cannabinoids packing technology do you need?

Vertical cartoner for pharmaceutical applications

High capacity cartoner for pharmaceutical applications

Horizontal cartoner for pharma and cosmetics

Pharmaceutical and cosmetic industry products cartoner

Automatic cartoner for applications in pharma and cosmetics

High-capacity horizontal cartoner for pharma and cosmetics appliances

High-speed small volume liquid filler

Monobloc small volume liquid filler

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