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flexible-intermediate-bulk-containers

Flexible-intermediate-bulk-containers

<span style="font-weight: 400">At last, you reached the final stage of processing your product - welcome to the packing world! Packing preserves and protects a product from damage, spoilage, and contamination while it makes its way from the production line to the consumer or further production. Depending on which industry your products belong to, the type of primary packaging equipment can change drastically. You need to pay careful attention to products with </span><span style="font-weight: 400">chemicals or hazardous substances since they can be potentially dangerous to human health. </span>

Packing

Bagging is the process of packaging measured portions of a product into bags that protect it from spoilage, enable easy and safe transportation, and secure the product against tampering and pilferage. The choice of bagging equipment depends on the desired mass or volume per bag, the flow characteristics of the product, and bag construction and design. Bags vary in size from small sachets to bulk flexible containers. Bagging systems are often the last processing step that is generally integrated into a production line.

Bagging

Adhesives are grouped according to their form, origin - natural or synthetic - and their material joining method. You can make natural adhesives from plant and animal sources such as bones, hide and skin, agar, dextrin. Manufacturers count with adhesive making equipment to produce synthetic adhesives from organic compounds. They include epoxy adhesives, cyanoacrylates (or super glue), acrylic adhesives and so on.

Adhesives

<p class="filterable-grid__description">Liquid dosage forms are designed for easy absorption. The body quickly carries the active ingredients through the system and triggers the required response. But the greatest advantage of this medicinal type is its flexibility in formulation and dispensation. From lotions and syrups to drops and sprays, liquid solutions can be adapted to different administration routes including parenteral, topical, and oral. The fundamental liquid dosage manufacturing process involves dissolving or suspending solutes in a fluid. But that is not enough. A precise blend of excipients is needed to make the medicine go down.</p>

Liquid dosage forms

Due to their potential hazardous nature, chemicals are classified for proper identification and safety during production. Chemical classification depends on their properties, structures and functions. In the chemical industry, you can regard them as basic chemicals such as acids, chemical products to produce plastic materials and finished chemicals for use in cosmetology. As a manufacturer or engineer, you want to know their reactivity when using chemical processing equipment.

Chemicals

A flexible intermediate bulk container is an industrial container designed for the transportation and storage of dry, flowable products in bulk packages. Selection of big bag filling equipment requires consideration of the type of particles to be packaged, type of bag to be used, filling weight/volume per bag, and production volume. Big bag filling equipment is used in the food industry for packaging seeds, spices, salt, and starch. In the pharmaceutical industry it is used for packaging of active ingredients; in the chemical industry for the filling of bulk chemicals, fertilizers, pigments, and plastic granules.

Industrial

In industrial settings where powders must be transferred from large bags to process equipment, maintaining control and safety is crucial. Efficient emptying of bulk materials minimizes contamination, spills, and product loss.
<h2>Discharge powders safely and efficiently</h2>
The Big Bag Emptying Station from De Dietrich Process Systems offers a contained, controlled environment to empty powders from Flexible Intermediate Bulk Containers (FIBCs) into subsequent processing steps. The station can handle everything from easy-flowing to highly consolidated powders and is customizable to meet unique plant requirements, whether for new installations or retrofits. Integration with the De Dietrich Powder Pump allows for seamless material transfer, while optional components like a fluidizing hopper, automatic bag tensioning, and high-containment cabinets enhance functionality. The station is controlled via PLC and HMI, suitable for hazardous areas, and can include batch weight monitoring. It’s an adaptable system designed for diverse industrial applications involving raw or intermediate powdered products.

Big bag emptying station for powder handling

Emptying

Handling

Integration

Powder

solid

Batch

Continuous

Management of big bags requires specialist handling and selection of cost-effective configurations for filling and weighing. Considerations also need to be made to for different bag contents; powder, granules, pellets or flakes.


<h2>Handle big bags of any product type quickly, easily and economically</h2>
Paglierani produces big bag filling machines and stations for weighing and bagging large dimension bags more easily and effectively. Designed for big bags and FIBCs (Flexible Intermediate Bulk Containers), they guarantee excellent performance, optimising production rates whilst minimising investment costs.

The BB simple series for weighing and bagging can be integrated into the BB equipped series which is complete with empty pallet dispensers and rollers that accumulate full pallets.

Big bag solutions

Pelleting equipment transforms powdered, mashed, or grounded material into a denser cylindrical shape. Pellet processing compresses the fine material against a perforated die, where it will be shaped and cut. Although granulating and extrusion also produce pellet-like products, manufacturing pellets is a distinct process.

Pelleting

There are many considerations when handling FIBC's (Flexible Intermediate Bulk Containers) or Big Bags, namely the kind of product, type of bag used, environmental aspects, system capacity and budget constraints. Bags need to be correctly hung, stretched and vibrated during filling to avoid unstable, poorly filled and unstackable bags. The major concerns when discharging bags are dust emissions, product loss and product contamination.


<h2>Safe and effective filling, weighing and discharge of Big Bags</h2>
TBMA has a wide range of expertise in the application of hygienic FIBC handling equipment, with proven reliability in practice, which allows correct assessment of the right system for every situation. TBMA Big-Bag filling systems can be supplied to handle weights ranging from 500 to 2000 kg. Filling capacities up to 70 bags per hour can be achieved depending on the type of product feed and system lay-out.

Hygienic FIBC handling line

Flexible intermediate bulk containers known as FIBC’s are commonly used in a wide variety of industrial processes. The pharmaceutical and bioprocess industries; however, require a higher degree of containment and a more carefully designed container. Experienced biopharmaceutical manufacturers know that equipment designed for general industry use often falls short and rigid containment and transfer solutions for the biotech industry are often awkward and inefficient. Producers that embrace flexible solutions designed specifically for the challenges of our industry will find an advantage over competitors.


<h2>A bulk transport and storage bag with superior product containment</h2>
ILC Dover is an industry leader in contained material handling solutions for high-tech manufacturers and end users including NASA. For transport and storage of bulk materials of a potentially more hazardous nature, the company has developed a bulk bag system with superior containment characteristics. Traditional FIBC’s often do not provide enough containment for use in the pharmaceutical and bioprocess industries. Their use in these industries can cause, compromised facility cleanliness, cross-contamination, and risk of employee exposure to unnecessary hazards. The G2PAC system from ILC Dover provides the same benefits as traditional FIBC’s like integrated lifting features and a 35” cubed size for easy use with standard pallets. However, this system also includes features that make it much more effective at containing products during transfer and storage. An inner liner is included made of ILC Dover’s ArmorFlex material that includes sleeves that are clamped to interfacing process equipment ensuring containment during transfer.  Individual sleeves are included to support both charging and offloading operations. The system can achieve containment levels down to 100ug/m^3 on an 8 hour TWA.

Flexible contained powder discharge into FIBC’s

Dosing systems are a line of hoppers, feeders, filling machines, and checkweighers that operate in sync to dispense materials accurately. Dosing is an essential feature of the packaging process, whether you’re filling shampoo bottles or tea bags. But dosing equipment is critical for formulations, too, particularly in the pharmaceutical and chemical industries. Imprecise dosing may cause quality degradation in the best-case scenario. In the worst scenario, it creates serious health risks.

Dosing

In industrial pelleting processes, consistently dosing powders is critical for achieving product uniformity and efficiency. Traditional methods often introduce variability and inefficiency, hampering overall production quality. Accurate loading of powders into feeders ensures seamless operation and quality control.
<h2>Precisely dose powders from big-bags</h2>
The Powder Dosing Big-Bag (PDBB) system by Hoopman Equipment is designed to facilitate the precise filling of a powder feeder for pelleting applications. The unit allows the use of big-bags to effectively dose powders by weight. By placing big-bags on designated funnels, users can fill the powder feeder with up to two types of powder per unit. If the setup does not allow enough hang-height for the big-bags, powder containers can be used as an alternative. The system is notable for its compatibility with different powder types and its design, ensuring that the bags bulge properly for smooth operation. This approach minimizes dosing errors and maintains product consistency, essential for quality pelleting processes.

Powder dosing system for big-bags

Filling lines are used extensively in all industries, such as food, pharmaceutical, chemical, and cosmetics, to accurately package different products into a container suitable for that product. Although the filling process is at the very end of the production line, it is no less important than the earlier steps. Last but not least, the idiom that dates back to 1382 when John Wyclif wrote the firste the laste, and the laste the firste, indicates just that the last things on a list are just as valuable as the previous ones. In this case, this idiom fits perfectly.

Filling

A loading system feeds your continuous or batch processing machine with the specified material or item in line with the flow of production. Loaders transfer the articles from one stage of preparation to the next with uniformity and accuracy.

Loading

When handling large volumes of powdered or granular materials, it's crucial to ensure a safe and dust-free environment. The risk includes potential dust exposure, which can be hazardous, and handling awkward and heavy Big Bags that might lead to safety concerns for operators.
<h2>Safely unload materials with minimal dust</h2>
The Modular Big Bag Unloading Station by Dinnissen ensures a safe and ergonomic product intake process. It allows the dust-free unloading of Big Bags, making it ideal for environments where both safety and efficiency are critical. Suitable for various materials including poorly flowing products, its modular design can accommodate numerous customizations. Options like an integrated hoisting system, negative pressure chamber for toxic products, and automatic weighing and dosing system can be added based on specific needs. This versatility allows the unloading station to fit seamlessly into different production lines, addressing stringent safety requirements and ensuring minimal residue in the bags. Dinnissen offers versions adhering to ATEX standards, making them suitable even for hazardous environments. The system’s efficient design allows it to be adapted both before and after the unloading process.

Modular big bag unloading station for various materials

Unloading

Weighing

In industries requiring the automated feeding of bulk materials into production systems, combining multiple sources like sacks and big bags can present challenges. Proper integration ensures efficient material handling, minimized dust, and optimized production processes.
<h2>Facilitates efficient bulk material loading</h2>
The combined pickup station from AZO is designed for both bagged products and big bags, offering flexibility and reliability in bulk material handling. The station can accommodate different loading methods, either by hanging big bags on mobile hoists or placing them on a loading table. The big bags are secured over the inlet pipe and clamped with a pressure disc, manually or pneumatically operated, allowing for easy discharge. For flow-resistant materials, auxiliary vibration or flexing devices ensure complete emptying. Alternatively, sacks can be opened and their contents discharged into a vacuum extraction hopper, which includes a filter to collect dust. This station is particularly useful for its ergonomic design and the capability to handle a variety of bulk materials in a closed and automated environment. Optional features such as textile insert winding devices and low level indication systems further enhance functionality.

Integrated pickup station for bagged products and big bags

Blending

Industrial feeding systems allows you to control the flow of solid bulk materials throughout the manufacturing line. After loading your material onto the vibrating hopper, a screw at the base drives it out in uniform doses to the next stage of processing. New feeding technologies are designed to deal with challenges of powders clumping together in the hopper (bridging and ratholing) that interrupt the outflow. Common feeder systems include centrifugal feeders, vibratory feeders as well as elevator, linear and pneumatic feeders.

Feeding

Vacuum

In industries handling bulk solids, managing dust during big bag connections poses significant operational challenges. Ensuring a clean and efficient discharge process is crucial for maintaining safety and minimizing environmental impact, especially with big bags lacking discharge spouts.
<h2>Ensures dust-free connection and efficient discharge</h2>
The Vac Docking system by AZO offers a reliable solution for the dust-free docking and discharge of big bags, ideal for those with no or short discharge spouts. This system consists of a cylindrical housing featuring a circumferential vacuum channel, creating a dust-tight seal upon contact. An underpressure generator forms a vacuum that prevents dust emission during discharge. This patented technology, registered under the number DE 20 2012 003 109.0 by the German Patent Office, facilitates quick and complete emptying of big bags. The construction from high-grade chromium-nickel steel ensures durability and ease of cleaning. Preferred for industries handling free-flowing bulk solids, the system streamlines operations by saving height and space.

Dust-free big bag connection system for bulk solids

Conveyor systems are used for moving materials from one location to another. Considerations for choosing a suitable industrial conveying system include the nature of the product, its physical state, the desired conveying rate, and sensitivity of the product to heat and mechanical shock. Conveying equipment is used in the food, pharmaceutical, chemical, biomass, and mineral industries to move materials around a warehouse as well as to transport bulk powders, granules, and grains for processing and filling. These types of systems are usually automated and there is a wide variety of solutions to choose when it comes to the type of conveyor. Types include screw, gravity, chain, roller and belt conveyors.

Conveying

Discharging

In the pharmaceutical and chemical manufacturing sectors, handling fine chemical powders poses challenges such as cross-contamination, precise dosing, and minimizing exposure to hazardous materials. Ensuring flexibility, safety, and scalability of processes is crucial for manufacturers aiming to maintain high production standards.
<h2>Achieve precise powder handling and contamination control</h2>
The Fine Chemical Powder System by Austar is designed to address the complexities of managing fine powders in pharmaceutical and chemical manufacturing. This system is adaptable to various production capacities, from large-scale automated operations for single product manufacturing to smaller, multifaceted workshops for handling multiple products. The equipment ensures minimal cross-contamination through strong tightness and diverse equipment combinations. It includes isolating devices such as isolators, glove boxes, and αβ valves for handling highly toxic and active raw materials. Additionally, automated unpacking devices, dust-free feeding systems, and vacuum conveying systems streamline the handling of raw materials packed in 25kg bags. For larger batches, FIBC systems for material transfer and positive pressure feeding bins for non-toxic materials in smaller quantities are utilized, maintaining safety and operational efficiency.

Fine chemical powder system

Industrial separation equipment encapsulates the separation process which is to separate components of a liquid mixture, for recovering dissolved solids from liquids. The choice of a suitable technology depends on the identification of the key physical or chemical property, such as size, mass, density, or boiling point, which sets the product of interest apart from the rest of the components. Separation technology is widely used in the pharmaceutical and chemical industries for the isolation of active ingredients and high-purity chemicals. As well as in waste management and recycling industries.

Separation

Almost all manufacturers will require industrial storage systems and solutions at some point during their production process. The raw materials that go into your products need dedicated storage solutions to protect them from spoilage and contamination before they enter the manufacturing cycle. Storage usually refers to particular storage space. For example, having enough warehouse storage. Or clearing out a production facility for more floor space.  However, in this case, we are referring to the equipment and solutions that make storage manageable and easier. Such equipment includes solutions such as storage racks, pallet racks and shelving systems. These are just some of many storage options available to manufacturers. Advanced technology facilitates the management of heavy duty and high density tank and silo systems by automating the delivery system and linking it with the rest of the production line.

Storage

When transitioning from refined oils to specialty fats, or enhancing existing facilities to handle these transformations, specialized processes for fat modification are essential. Challenges include achieving precise modifications, maintaining product integrity, and ensuring efficient use of resources.
<h2>Optimize fat modification with flexible, integrated systems</h2>
The fat modification process systems offered by Alfa Laval cover a range of techniques such as fat hardening, chemical or enzymatic interesterification, dry fractionation, and semi-continuous deodorization. These processes can be integrated with an upstream refinery, work as standalone processes, or supply feedstock to downstream facilities like margarine or shortening lines. Each system is designed with flexibility in mind to handle different specialty fats daily, utilizing minimal water and energy. For example, the fractionation process gently cools oils or fats in a precisely controlled manner, enabling separation into liquid and solid fractions without chemical modification. The hydrogenation process modifies oils and fats at temperatures of 150-200°C, improving their melting points, taste, and shelf life. The interesterification process allows combining various oils and fats to produce hard fats while maintaining consistency across different temperatures. Alfa Laval offers customizable solutions and equipment can meet various production needs within the edible oil industry.

Fat modification process systems

liquid

Active pharmaceutical ingredients demand high handling standards to prevent cross-contamination. Moreover, the processing of materials creates risks to occupational safety and health, especially where highly potent APIs are involved. But, while formulas may be kept separate during processing, loading them into different bagging machines leads to production inefficiencies.
<h2>Modular big bag filling equipment for powdered process bulk materials</h2>
Big Bag Filling station from Dec Group is a universal solution for the direct filling of big bags .  The station integrates into other process equipment like mixers or driers with gravity-assisted filling. In cases where headroom is limited, the station can be modeled for remote-filling instead. Here,  powder transfer technology moves the materials through a valve system for correct dosing.

The holding frame is either painted steel or stainless steel and has a big bag loop holder with a fast-release mechanism. The Big Bag Filling station includes a range of other solutions, including sieving, milling, metal detection and separation, sampling, weighing, and precise dispensing. The equipment uses a standard pallet jack for easy installation of pallets.

Big bag filling machine

Dust emissions, product loss and product contamination are the main risks when discharging products from different types of Big Bags. Variations in type of product, bag, environmental aspects, system capacity and budget can make selecting a big bag discharge system challenging.


<h2>Discharge single or multi-trip bags cleanly and safely</h2>
The TBMA range is based on a simple but very flexible modular concept, whereby the basic models can be extended with several options to obtain a complete solution for discharging Big Bags with or without plastic liners.
Suitable for free flowing or poor flowing products, the specially designed liner clamping mechanism enables a dust-free seal of the liner before product flow is allowed into the downstream system.
Each discharger can be supplied with a wide range of ancillary equipment for further dosing and conveying of the discharged products.

Big bag discharge system

Powdered products are handled every day in the pharmaceutical and bioprocess industries and an efficient means of filling drums while maintaining containment is needed to ensure safe and profitable production processes. Experienced biopharmaceutical manufacturers know that equipment designed for general industry use often falls short and rigid containment and transfer solutions for the biotech industry are often awkward and inefficient.  Producers that embrace flexible solutions designed specifically for the challenges of our industry will find an advantage over competitors.


<h2>A disposable drum liner  for continuous production of powders</h2>
ILC Dover is an industry leader in contained material handling solutions for high-tech manufacturers and end users including NASA. For powder discharge into drums, the company has developed the Dover Pac system. The Dover Pac Continuous Liner is typically used to offload powders from vessels into drums for the pharmaceutical and bioprocess industries. The liners interface directly with existing process equipment including down-flow booths and isolators. The liners are continuous which both eliminates cross-contamination of powders, and enhances operation efficiency by eliminating the need for the operator to constantly place new liners over a discharge nozzle as with traditional drum liners. The liners are shipped in pack lengths of 15 M to 45 M with each standard drum using about 1.5 M of liner material. Drums are continuously filled until the liner pack is spent. Spent packs are easily replaced by an operator without breaking the containment of the powder. The continuous liners are available for use with 580mm, 355mm, or 200mm canisters with adapters available for interfaces to smaller canisters if required.

Flexible contained powder discharge into drums

The essential objectives of containment systems are personnel protection and preventing the release of toxic or infectious material into the environment. Containment is also used to prevent a product or sample from contamination by the external environment. In the chemical and pharmaceutical industries, containment solutions are used to protect the personnel from the leaking of airborne particles of hazardous substances, as powders or liquids are handled or transferred during processing.

Containment

Transferring powders from drums to process equipment such as reactors or mills can create dusty and hazardous conditions in a manufacturing environment and can be a source of worker exposure to hazardous substances in the pharmaceutical and bioprocess industries. Experienced biopharmaceutical manufacturers know that equipment designed for general industry use often falls short and rigid containment and transfer solutions for the biotech industry are often awkward and inefficient. Producers that embrace flexible solutions designed specifically for the challenges of our industry will find an advantage over competitors.


<h2>Safely and easily empty powder drums without sacrificing containment</h2>
ILC Dover is an industry leader in contained material handling solutions for high-tech manufacturers and end users including NASA. The company's flexible contained drum transfer system allows operators to empty the powdered contents of drums used in the pharmaceutical and bioprocess industries without exposure to the contents. The contents are also protected from potential contamination during the transfer process using this equipment. A flexible containment chamber made from ILC Dover’s rugged Armorflex material is anchored to a raised stainless steel frame using ergonomic bungee cords. The containment chamber includes a discharge sleeve, a drum sleeve, and 2 glove sleeves for operator manipulation of the drum lid and internal liner under contained conditions. A closed drum is placed on the integrated pneumatic drum lift and the drum sleeve is attached. The discharge sleeve is attached to a ring in the frame designed to interface with downstream process equipment. The containment chamber is at a height off the floor which allows the powder to be gravity fed into downstream process equipment or containment solutions placed under it. The operator then raises the drum to the containment chamber with the simple actuation of a lever and opens the lid using the integrated glove sleeves. This manual interaction allows the operator to ensure that all powder flows out of the drum liner to the next process stage without being directly exposed to it. When the drum is empty, its spent liner is placed inside of it and its lid replaced. It is then lowered back to the floor and discarded. The sleeves in the flexible containment system are twisted closed and crimped off ensuring no powder contamination of the surrounding environment. The containment chamber is then discarded and the process repeated for each new drum to be transferred.

Flexible contained drum transfer system

Maintaining the purity of products as well as avoiding worker exposure to potentially harmful substances are critical to any biotech process and often there is no better way than a glove box to achieve these goals while allowing for manual handling of the materials. Experienced biopharmaceutical manufacturers know that equipment designed for general industry use often falls short and rigid containment and transfer solutions for the biotech industry are often awkward and inefficient. Producers that embrace flexible solutions designed specifically for the challenges of our industry will find an advantage over competitors.


<h2>A quickly implemented, low capital expenditure glove box for the biotech industry with excellent operator ergonomics</h2>
ILC Dover is an industry leader in contained material handling solutions for high-tech manufacturers and end users including NASA.  Making use of the company’s ArmorFlex brand of rugged plastic film designed for the biotech industry, the DoverPac Flexible Containment Technologies line of containment solutions are a glove boxes ready to be used to support your process with little capital expenditure and low implementation time.  The glove boxes consist of a stainless steel frame built to your requirements that is lined with a layer of ArmorFlex film.  The Armorflex is clear and highly flexible but is supported by the frame to form a convenient operator workspace.  Gloves and sleeves are integrated into the film and supported at the front of the frame.  Using these sleeves, an operator can manipulate items in the chamber without risk of exposure to contamination. The use of the simple frame and flexible clear plastic film make these units less expensive than traditional glove boxes while allowing better operator ergonomics by avoiding a fixed rigid containment box and limited viewing ports.

Flexible enclosures

Flexible disposable containment systems in the form of specially designed plastic bags are an excellent choice for addressing powder transfer challenges.  However the bags must be sealed in a way that economical, easy to use, and above all,  reliable.  Experienced biopharmaceutical manufacturers know that equipment designed for general industry use often falls short and rigid containment and transfer solutions for the biotech industry are often awkward and inefficient. Producers that embrace flexible solutions designed specifically for the challenges of our industry will find an advantage over competitors.


<h2>A reliable bag closure system designed for pharmaceutical processing</h2>
ILC Dover is an industry leader in contained material handling solutions for high-tech manufacturers and end users including NASA. The company's CripmLoc system reliably closes flexible containment systems (often in the form of a plastic bag) to ensure containment and contamination avoidance during and after powder transfer operations for the pharmaceutical and bioprocessing industries.    The system includes an ergonomically designed applicator gun and one-time-use plastic crimps of various sizes.  Two plastic crimps are loaded into the gun in preparation for the closing operation.  Each crimp completely closes the bag when installed.  Two crimps are simultaneously installed by a single actuation of the gun.  Cutting between the crimps thus allows areas of the bag to be separated from one another without losing containment of either section.  The flexible containment system is twisted in the area to be closed with the plastic crimp clamping the twisted material together maintaining closure.  Each crimp also includes a snap-in-place cap that covers the cut end of the twisted bag—further ensuring containment and resistance to infiltration of contaminants.  Crimps are readily removed by the gun by applying pressure to a particular surface of the closed crimp causing it to separate—this avoids the issue of potential plastic shard contamination when other closing devices are cut or broken during removal.

&nbsp;

Crimping system

Poly bottles with split butterfly valves are often used to transfer powders from bulk containment equipment to the point of use while avoiding cross contamination.  However, rigid bottles present several challenges which hinder production and reduce process efficiency.  Experienced biopharmaceutical manufacturers know that equipment designed for general industry use often falls short and rigid containment and transfer solutions for the biotech industry are often awkward and inefficient. Producers that embrace flexible solutions designed specifically for the challenges of our industry will find an advantage over competitors.


<h2>A powder transfer solution for split butterfly valve operations with excellent product recovery and no required cleaning</h2>
ILC Dover is an industry leader in contained material handling solutions for high-tech manufacturers and end users including NASA. The company's Standard Doverpac SF system is a powder transfer solution for split butterfly valve operations that replaces the polybottles traditionally used in these applications.  The system consists of a rugged plastic bag with a split butterfly valve type adapter on the bag’s sole opening. After interfacing with your equipment via the split butterfly valve, the bag is filled and removed and its side of the valve adapter closed. Its contents are then carried to the next point of use and emptied from the bag via the split butterfly valve interface. The bag is one time use and disposed of after emptying—avoiding the need for cleaning and cleaning validation.  New bags are stored in a tightly folded package—reducing the storage space required when compared to poly-bottles. The plastic bags are specifically designed for optimum powder flow and product recovery rates better than 99.5% can be achieved.  A removable and reusable physical restraint consisting of a durable fabric sling with integrated lifting features is available for use to contain and protect the plastic bag during transfer operations.  Use of the physical restraint allows exposure to pressure differentials up to .499 bar with a 2x safety factor.

Flexible contained charging for split butterfly valves

Filling of transportation bags and discharging them into mix tanks or reactor vessels is often a source of contamination and there potential exposure of personnel to harmful substances.  Inadequate measures to avoid these issues often slow production and reduce profitability.  Experienced biopharmaceutical manufacturers know that equipment designed for general industry use often falls short and rigid containment and transfer solutions for the biotech industry are often awkward and inefficient. Producers that embrace flexible solutions designed specifically for the challenges of our industry will find an advantage over competitors.


<h2>A fast and clean powder transfer solution for maximum containment during both charging and offloading operations</h2>
ILC Dover is an industry leader in contained material handling solutions for high-tech manufacturers and end users including NASA. The company's DoverPac system provides high levels of reliable containment during both charging and offloading operations.  The system consists of a durable fabric bag with a tough plastic film liner.  The liner includes an upper sleeve for containment during the bag filling operation and a lower sleeve for containment during the offloading operation.  The fabric bag includes lifting points for crane hoisting and serves as a physical restraint keeping the liner and contained powder in a regular and protected shape during transport.  The discharging sleeve at the bottom of the liner includes 2 smaller lateral sleeves which allow for powder sampling for QC without breaking containment.  Both the upper and lower sleeves are manually clamped to your bulk storage hopper, mix tank, or reactor vessel and designed to be crimped, cut off, and eventually removed all while maintaining isolation and containment of the inside of the bag and the interior of your equipment.  In this way, the system provides maximum containment during powder transfer with the ease of use of a simple bag transfer material handling system.

Flexible contained powder charging solution

Filling of transportation bags and discharging them into mix tanks or reactor vessels is often a source of contamination and there potential exposure of personnel to harmful substances.  Inadequate measures to avoid these issues often slow production and reduce profitability.  Experienced biopharmaceutical manufacturers know that equipment designed for general industry use often falls short and rigid containment and transfer solutions for the biotech industry are often awkward and inefficient. Producers that embrace flexible solutions designed specifically for the challenges of our industry will find an advantage over competitors.


<h2>A fast and clean flexible powder transfer system</h2>
ILC Dover is an industry leader in contained material handling solutions for high-tech manufacturers and end users including NASA. The company's EZ BioPac is a single use solution to contamination free powder transfer for the bioprocessing and pharmaceutical industries.  The system consists of a rigid polypropylene stand with an integrated plastic bag.  The stand holds the bag in an open funnel shape for filling and doubles as a lifting point when the bag is ready to be emptied from the bottom.  The bag is oversized and includes enough material to fold back over the stand during filling to protect the stand from any spillage during filling.  The funnel shape of the supported bag in the filling configuration allows for easy manual addition and subtraction of material to ensure accurate fill weights.  A charge neck at the bottom is clamped to your reactor vessel or fill the tank for discharging and a system of clamps is used to manually control material flow and seal the bag for disposal after it is empty.  Isolation of the contained material is thus maximized, greatly reducing cross-contamination of the powder by substances from the work area, and of the work area by the handled powder.

Flexible contained handling of powder transfer bags

Biotech equipment is used for cellular and biomolecular processing to develop products that improve our lives and the planet. With the help of specialized lab equipment, the active substance is manufactured or extracted from biological origin materials and typically produced in bioreactors by plant cells, microbial cells, yeast cultures, or mammalian cells. Cell isolation, cultivation, cell banking, and culture expansion are called upstream processes. After harvest, the production process moves into a downstream process to meet purity and quality requirements which is divided into cell disruption, purification, and polishing. Biotechnology equipment makes use of various laboratory machinery such as bioreactors, centrifuges and incubators.

Biotech

Flexible intermediate bulk containers

Plastic pollution is one of the biggest climate-related problems mankind has. So what are your options? A bioplastic machine can help create an alternative to traditional plastics. Bioplastics, differently from regular plastics, don’t cause environmental contamination. Also, they don’t contain harmful ingredients and additives. Even with these benefits, the annual production of bioplastics is still less than one percent of all plastic making. However, the market is witnessing steady growth due to a rise in demand.

Bioplastics

Carbon blacks are fine pigment particles that consist mainly of carbon. Its production became popular in the second century with the establishment of paper production. Hydrocarbons such as oil and natural gas are the basic raw materials for manufacturing them. However, the properties of carbon black differ depending on the processes carried out with the use of carbon machinery and production technology.

Carbon black

Crickets are better known for their nighttime serenades than for their nutritional notes, but their serious protein content as well as vitamin B12 content and iron, moves them into the category of superfoods. With a light brown color and a nutty taste, cricket protein powder is a versatile dietary ingredient that makes it difficult to go off-tune with your recipes.

Cricket protein

Dyes lend color to the things we consume. The foods we eat, the clothes we wear, and even the keyrings that separate your bunch all have a splash of dye added. Historically, colors were extracted from the natural world, but that process has been replaced by processing technology. Dye manufacturing equipment produces colors that are high in definition and consistency.

Extruded aquafeed

In the feed sector, it's common to talk about feed as balanced, compound, or concentrate. Many people use one of these terms to refer to any feed mill product. However, the processing of feed concentrates, only requires grinding and mixing. The further transformation into pellets adds is an added value for the market.

Feed concentrates

Feed premix delivers a quality blend of macro and micronutrients to meet the overall growth and health needs of animals. Although they constitute a small portion of the feed, they provide enormous benefits by adding a balanced, nutrient-rich feed that supports the animal health. Feed premix making equipment ensures a proper combination of important ingredients to generate a perfect blend.

Feed premixes

The fishmeal powder market forecast shows that its global market value will reach USD 10.3 billion by 2025. Expanding since 2019, at an annual growth rate of 6.5%. Fishmeal powder production has strong business potential with the increase of applications in animal feed, pet food, and fortified foods.

Fishmeal powder

There are two misconceptions about floating pellets. The first one is that they are made with a pellet mill, when the proper floating pellets-making machines are extruders. The second misconception is that floating feed is only used for fish. However, many other species consume feed on the water, such as crocodiles and birds.

Floating pellets

Fodder

When he was in Haiti in 1493, Christopher Columbus noticed that the natives were bouncing on rubber balls made from the milky sap of Hevea brasiliensis, also known as a rubber tree native to South America. The milky sap was nothing but latex, the source material for natural rubber. Latex processing technology includes equipment for coagulation techniques and rollers for natural latex and a sequence of mixers, pumps, and sieves for synthetic latex.

Latex

Also known as color concentrates for plastics, masterbatches are plastic granules that contain additives for coloring plastics. Their major purpose is to bring vibrance and improve the final product's appearance. In the process of making them, masterbatch production equipment is used to combine two major constituents—colorants and polymer-specific carriers.

Masterbatches

Growing populations and intensive farming in the last centuries reduced soil nitrate levels. Aware of the risks to food security, chemists Fritz Haber and Carl Bosch developed a way to industrialize synthetic nitrogen fertilizer production. They created the Haber-Bosch process for ammonia synthesis which is still used today. Manufacturers produce over a hundred million metric tons of nitrogenous fertilizers every year.

Nitrogen fertilizer

Poultry feed

Unlike natural resins, synthetic resins produced in the industry make up 30 to 60% of plastic composition. Silicone resins, gum arabic, epoxy resins, acrylic resin and carrageenan are some of the different types of synthetic resins that exist. You manufacture them using the chemical polymerization process. Synthetic resin making equipment can help you with that.

Synthetic resin

As traced back to the first half of the 19th century, attempts at synthetic rubber production were simply to reproduce the original material due to the rubber shortage following World War II. Synthetic rubber production processes differentiate between producing the rubber, which can be done via solution polymerization and emulsion polymerization and creating the final product with the help of techniques such as molding and vulcanization.

Synthetic rubber

A toner is a fine powder located in printer and copier cartridges. One peculiar property the product is their ability to act like liquids. Toner manufacturing equipment sees to it that the particle size is between 5 and 30 micrometers to flow through the cartridge.

Toner

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