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Plant extracts purification

Echinacea, also known as coneflowers, are brightly hued flowers with distinguished, cone-shaped flower heads. Over 200 medicines in the world are derived from coneflower extracts. Echinacea processing was introduced by Native Americans who were interested in the plant's medicinal qualities.

Echinacea extract

Elderberry falls squarely in the category of superfoods. Every part of the plant (flowers, berries, and bark) is loaded with vitamins, antioxidants, bioflavonoids, and other compounds. However, cyanide in the plant could be lethal if consumed raw, making elderberry extraction processing complex.

Elderberry extract

Only one percent of the entire plant species on the planet produces essential oils, but that amount has found its way into various products, from perfumes to foods. Flower extraction systems are similarly diverse, and picking the right ones depends on the organic material and the final product.

Flower extract

What’s the only living connection between our present world and the age of dinosaurs? The ginkgo biloba plant. Also known as the maidenhair tree, it is regarded as a living fossil and has been around for more than 200 million years. Ancient civilizations in China were already mastering ginkgo processing centuries ago and the tradition soon flourished around the world.

Ginkgo extract

Panax ginseng is a medicinal plant with a long history steeped in myth. The term “panax” itself is derived from a Greek word for “panacea” or “cure all”. As ginseng processing technology continues to develop, this famous traditional extract keeps finding new applications.

Ginseng extract

Oleochemicals

In the feed sector, it's common to talk about feed as balanced, compound, or concentrate. Many people use one of these terms to refer to any feed mill product. However, the processing of feed concentrates, only requires grinding and mixing. The further transformation into pellets adds is an added value for the market.

Feed concentrates

All plastics are polymers, but not all polymers are plastics. Polymer production is a multi-step process that transforms raw materials into products that we use in our day-to-day life with the help of polymer process equipment such as extruders, calenders and injection molding machines.

Polymers

Salt

When he was in Haiti in 1493, Christopher Columbus noticed that the natives were bouncing on rubber balls made from the milky sap of Hevea brasiliensis, also known as a rubber tree native to South America. The milky sap was nothing but latex, the source material for natural rubber. Latex processing technology includes equipment for coagulation techniques and rollers for natural latex and a sequence of mixers, pumps, and sieves for synthetic latex.

Latex

Continuous distillation process

Very low operating pressures

Short residence time

High evaporation rates

Low fouling on evaporator wall

Short Path Distillers

Chemical

Food

Pharmaceutical

Industrial Purification Systems

Purification is the removal of contaminating substances and by-products to increase the level of purity of the desired substance. Considerations for choosing a suitable purification system in the industry, include the physical state of the mixture, the desired product, required level of purity, the type of mixture, heat sensitivity of the product, number of purification steps needed, and the production volume. Industrial purification systems are used for the production of pure water in the food pharmaceutical and biotech industries.

Purification

Connect directly with world leading manufacturers of industrial purification systems and find technology to build or improve your production line.

Purification &#8211; Making.com

Industrial Purification Systems - Making.com

Biopharmaceuticals are drugs in which the active substance is manufactured or extracted from biological origin materials. They are usually produced in bioreactors by plant cells, microbial cells, yeast cultures, or mammalian cells. Also known as biomanufacturing, they are used to either treat or diagnose and prevent a patient’s medical condition or disease. Biopharmaceuticals are typically complex macromolecules administered by injection or infusions, and examples include vaccines, serums, and insulin.

Biopharmaceuticals

Cannabinoids are natural compounds obtained from the Cannabis sativa plant. Delta-9-tetrahydrocannabinol or THC is a psychotropic substance. Cannabidiol, or CBD, is non-psychotropic and often used for nutraceutical purposes. Cannabinoid equipment extracts THC and CBD from the plant and prepares the substance for formulations that treat pain, nausea, anxiety, and inflammations. Cannabinoids are processed in various forms, including creams, capsules, and oils.

Cannabinoids

Due to their potential hazardous nature, chemicals are classified for proper identification and safety during production. Chemical classification depends on their properties, structures and functions. In the chemical industry, you can regard them as basic chemicals such as acids, chemical products to produce plastic materials and finished chemicals for use in cosmetology. As a manufacturer or engineer, you want to know their reactivity when using chemical processing equipment.

Chemicals

Essential oils are known as the liquid gems of nature. The sweet-smelling essences impact not just our senses but also our biochemical and cellular make-up. Besides aromatherapy, the products of an essential oil extraction system found applications in pharmaceuticals and foods.

Essential oil

Our food chain starts in the soil, growing crops and livestock. But between the fields and the stores, there is a line of industrial food processing equipment. Processes may be as minimalistic as cleaning fruit and as complex as homogenizing milk alternatives made from pressed legumes. In each case, processing technology is an important link in the food production chain.

Fruit pulp is a mass of pressed fresh fruit not meant for immediate consumption. Production of fruit pulp avoids wasting food and preserves the flavors and nutrient value of the fruit product. Processed fruit pulp is an ingredient in beverages, sauces, baby foods, jellies, smoothies, and bakery products.

Tradition and manufacturing procedures dictate the distinction between fruit juice, puree, and pulp. Still, naming and labeling are complex and depend on regulations, type of fruit, texture, consistency, preservation methods, and sugar or solid content (measured in Degrees Brix). Depending on your desired output, there are various fruit pulper machines for different stages of production that make the process quicker and more efficient.

Fruit pulp

Pharmaceutical developments walk side by side with health advances to provide new medicines, treatments, and therapies that have increased life quality and extended life expectancy by years. Pharmaceutical manufacturing equipment helps deliver products to a great deal of the population, but there’s a significant share that doesn’t benefit from them yet. Over 2 billion people cannot get the medicines they need, according to the United Nations Industrial Development Organization, and local production might be a way to provide for these people.

Pharmaceuticals

Ancient civilizations discovered that plant extracts were useful for the treatment of pathologies. The origin of plant extraction cannot be specifically verified, but we can infer that the earliest attempts at plant extraction were more intuitive than scientific. Today, the extraction of compounds is a precise process with plant extraction systems complimenting traditional knowledge.

Plant extracts

Can it be said that we live in the Plastic age? Basically, yes. From pillows over toothbrushes, and packaging to utensils, plastic is a widely used material in our day-to-day lives. But what is it? Plastics are synthetic or semi-synthetic materials built of polymers that are easily shaped into various structures with the help of plastic processing equipment such as extruders and molders.

Plastics

Process

Continuous

Evaporation technology is used to reduce or remove the moisture content of a mixture. Considerations for choosing suitable evaporation equipment include the moisture content in the mixture, the boiling point of the solvent, heat sensitivity of the product, and the amount of material to be processed. Evaporators are used for applications such as obtaining fruit and vegetable concentrates in the food industry, concentrating aromas and herbal extracts in the cosmetics industry, and isolating active ingredients in the pharmaceutical industry.

Evaporation

Industrial separation equipment encapsulates the separation process which is to separate components of a liquid mixture, for recovering dissolved solids from liquids. The choice of a suitable technology depends on the identification of the key physical or chemical property, such as size, mass, density, or boiling point, which sets the product of interest apart from the rest of the components. Separation technology is widely used in the pharmaceutical and chemical industries for the isolation of active ingredients and high-purity chemicals. As well as in waste management and recycling industries.

Separation

liquid

The special design of short path evaporators by VTA allows operating pressures down to 0.001 mbar.

With short path distillation, a substantial decrease of boiling temperature is obtained by reducing the operating pressure. It is a continuous process

Short path evaporators &#8211; Making.com

We open production technology to everyone

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The humble chamomile flower holds a rich blend of compounds that soothe body and mind. A natural antidepressant and anti-inflammatory, chamomile oil found its way into the earliest pharmacopeia. As more of its properties were discovered, the oil became an elemental ingredient for a vast range of pharmaceutical and cosmetic recipes. Chamomile oil processing equipment developed at the same speed, offering manufacturers multiple production techniques to extract the liquid from the precious flower.

Chamomile oil

Koala bears diet exclusively on eucalyptus leaves. But the large concentration of cineole in the tree keeps most other predators at bay. Humans, though, discovered ways to extract the substance and use it as a remedy against inflammations and other diseases. The eucalyptus oil production process keeps evolving to maximize yields, ensuring enough eucalyptus forests for koalas.

Eucalyptus oil

Lavender oil is one of the most common essential oils in the market currently. Extracted from the herb Lavandula spp., this essential oil is used as a complementary medicine and as an additive. Studies have shown that lavender oil has sedative, carminative, anti-depressive, and anti-inflammatory properties. Like other essential oils, lavender oil extraction equipment must be capable of distillation, condensation, collection, and separation processes.

Lavender oil

Rose oil is an essential oil extracted from the petals of either Rosa damascena and Rosa centifolia. Also known as liquid gold, rose oil production originated from Greece and is currently manufactured mainly in Bulgaria, Turkey, and Morocco. Studies have shown that rose oil has medicinal properties, exhibiting anti-inflammatory, anti-infective, and wound healing actions.

Rose oil

Tea tree oil, also known as melaleuca oil, is an essential oil with immune system stimulants produced mainly in Australia. The tea tree oil manufacturing process starts from the leaves of Melaleuca alternifolia. In terms of market value, the one for tea tree oil was valued at 38.8 million USD last 2017 and is projected to increase to 59.5 million USD by 2025.

Tea tree oil

Provides visual observation of the distillation process

A variety of size selection is available based on customer's requirement

Proper and reliable tests can already be performed with 2 kg of crude material

Continuous feeding systems and continuous discharging systems for distillate and residue options can be selected

R&amp;D

Batch

Industrial distillation equipment is used in the process of separating different constituents of a liquid mixture. Considerations for choosing suitable distillation systems include the boiling points of the components, heat sensitivity of the product of interest, pressure requirements during the process, and the scale of production. Distillation is used for concentrating extracts such as herbal extracts, flavors, and aromas in the food industry. In the pharmaceutical industry, distillation is used in the production of active ingredients and in the chemical industry for the purification of chemical products.

Distillation

The VTA Laboratory short path distiller integrate the short path distillation technique and are set-up as modules.

Get to reliable conclusions for the separation of high-boiling and heat-sensitive products using as little as 2 kg of crude material. Small scale thermal

Laboratory short path distiller &#8211; Making.com

The ancient Greeks believed feeding sea buckthorn to their horses would give them a lustrous hide. Indeed, full of lipids and carotenoids, the fruit did contribute to glowing, reddish coats. However, the thorny plant also has benefits for humans. Sea buckthorn processing equipment extracts this unique vegetable oil full of fatty acids. The liquid is a prominent component in various food, cosmetic, and pharmacological preparations.

Sea buckthorn oil

Everything tastes like porridge, the saying goes. That may be an exaggeration, but in theory, reaction flavors could make everything taste the same. Thankfully, flavorists and chemists in the flavor industry are more inventive than that, and colorful process flavors treat our taste buds to a broad palette of sensations, flavors and aromas.

Reaction flavors

Mineral water is mother nature’s cocktail of dissolved solids. The concentration of essential chemicals in the water makes it an excellent source of nutrients and electrolytes. Although your bottled product retains most of the properties present at its natural condition, the water still needs some help before it can be safely consumed.

Mineral water

Can be operated at pressure range of 0.1 mbar to 1,000 mbar

Can handle material with max. Viscosity of 15,000 mPas (cP) at operating temperature

Options of continuous feeding systems and continuous discharging systems for distillate and residue can be selected

Wiped film distillers

The VTA wiped film distillation laboratory unit is designed to distill small product quantities for acquiring reliable data of the separation process.

Reach reliable conclusions testing the distillation of high-boiling or highly viscous material using as little as 2 kg of crude material. Small scale

Laboratory wiped film distiller &#8211; Making.com

Can be configured based on customer's requirement

PLC and visualization option can be selected

Can process temperature sensitive high boiling products

Can handle viscous and fouling products

The VTA Laboratory multi-stage distiller is a combination of the short path and wiped film distillation technique.

A laboratory multi-stage distillers that combines the wiped film and short path distillation technique allows you to test the separation of high-boiling,

Laboratory multi-stage distiller &#8211; Making.com

Fish oil was a folk remedy long before scientists identified the nutritional value of essential fatty acids. But Omega 3 processing has come a long way since the days of raw fish parts fermenting in a barrel. In fact, new supplement formulations of polyunsaturated fatty acids (PUFAs) may not use fish at all.

Omega 3 oil

The rapeseed flower evolved high concentrations of substances that are anti-nutritive at best and toxic at worst. But new varieties developed in the 1970s lowered the content of glucosinolates and erucic acids. From then, the use of oilseed rape spread to several applications, from edible oil to biofuel to animal feed. Rapeseed oil processing technology has thus become foundational to industries spanning food production, energy, cosmetics, and pharmaceuticals.

Rapeseed oil

Can be operated at pressure range of 0.001 mbar to 1,000 mbar

Can handle highly viscous material with max. viscosity of 15,000 mPas (cP)

Products with high boiling points at 0.001 mbar can be evaporated

Pilot short path distillers are set up as modules and used to separate small product quantities that will enable a later scale up to an industrial system.

Generate scalable data and results during the pilot tests with short path distillation, distill or dry of small product quantities with as little as 30 kg

Pilot short path distiller &#8211; Making.com

Processing of high-boiling, high-viscosity or crystallizing product are possible

Can be combined with additional evaporation stages

Pilot wiped film distiller units are used to process small product quantities that will enable a later scale up to an industrial system.

Generate scalable data and results during the pilot tests with wiped film distillation,  distill or dry of small product quantities with as little as 30

Pilot wiped film distiller &#8211; Making.com

Nut oil

Configuration based on customer's requirement is possible

Pilot multi-stage distiller combines short path and wiped film distillation methods to helo you achieve the quality of your product.

If generating an scalable data and bring in results with small sample quantities of high-boiling, heat sensitive and highly viscous products using a short

Pilot multi-stage distiller &#8211; Making.com

  Can be combined with a column to increase the number of theoretical plates

Separate high-boiling and highly viscous materials in a wiped film evaporator.

With wiped film distillation, a substantial decrease of boiling temperature is obtained by reducing the operating pressure. It is a continuous process

Wiped film evaporator &#8211; Making.com

<h3>Plant extraction equipment relies on heat treatment</h3>
Conventional extraction processes such as maceration, decoction, infusion, digestion, percolation, and hydrodistillation remain effective. But <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398001/" target="_blank" rel="noopener">advanced techniques</a> such as ultrasound-assisted extraction and microwave-assisted extraction reduce the heat impact on the target compounds.

An alternative technique uses the solvent extraction method, such as ethanol and C02, to dissolve the plant material and absorb the oils. The solvent is then evaporated, releasing the plant extract. Depending on the type of solvent used, high or low temperatures raise the levels of solubility and diffusion, but excessive heat risks perishing thermolabile components.

Place the plant in an oven with a temperature range above 40°C but not exceeding 50°C. In the case of delicate plants, freeze-drying <a href="https://www.intechopen.com/online-first/77433" target="_blank" rel="noopener">protects the thermolabile compounds</a>. Set drying temperatures to between -60°C and -80°C

Drying the materials before they are processed by plant extraction machines preserves them from enzymatic degradation.

Set drying temperatures to between 40°C and 50°C

In addition to featuring prominently in the pharmaceutical, cosmetic, and food industries, plant extracts are useful for animal care. Extracts derived from various plants are effective at <a href="https://parasitipedia.net/index.php?option=com_content&amp;view=article&amp;id=2553&amp;Itemid=2837" target="_blank" rel="noopener">destroying parasites</a> that target pets and livestock.

In fact, several plants contain natural active ingredients such as geraniol and eugenol that are deadly to pests. These chemical compounds in these plants are effective against parasites.

Plant extract applications in the animal care sector

<h3>Plant extraction technology oriented towards active packaging</h3>
Plant extracts can be applied to Active Packaging solutions. This novel procedure incorporates <a href="https://ift.onlinelibrary.wiley.com/doi/epdf/10.1111/1750-3841.12492" target="_blank" rel="noopener">antimicrobial compounds</a> in the plants in packaging film solutions.

The hydrophobicity of essential oils forms a boundary wall to minimize the migration of water vapor through the film. Meanwhile, the natural antioxidative properties in plant extracts add a protective layer to the packed products.

Plant Extraction Equipment

Connect with world-leading equipment manufacturers to find process and packaging technology for plant extraction and build and improve your production line.

Plant extracts &#8211; Making.com

Plant Extraction Equipment &#8211; Making.com

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The traditional method for gummy and jelly production uses starch to keep the ingredients from sticking to the mold trays. But, as an organic byproduct, starch raises concerns about microbial contamination. Moreover, starch leads to coarser edges of individual sweets, lowering the quality of the end products. The use of starch presents many hygiene and cross-contamination risks, as well as efficiency, quality and financial compromises.

<h2>Make high-definition gummies that are free from starch</h2>
The ServoForm Flexi system for gummies and jellies from Baker Perkins is designed for starch-free production. Starch-free depositing is both more hygienic and economic than traditional starch mogul production for the lower throughputs that are typically required for functional, nutraceutical and healthcare markets.

The ServoForm Flexi system offers the capability to produce gummies and jellies with longer setting times. 3D, solid, striped, centre-filled and layered products with gelatin, pectin or specialized gelling agents are deposited at final solids so no drying is required, only setting/conditioning.

A unique single-piece plastic mould allows for rapid product changeovers. The strong, rigid construction provides resistance to twisting to maintain depositing accuracy and stack stability, and is designed to survive both manual and automatic handling for multiple cycles. They are temperature resistant to allow hot product and automatic washing.

Flexible Output Line For Gummies and Jellies

Gummies make everything more colorful. The squishy droplets make a tasty and practical carrier of special ingredients such as CBD oil. Chewing the gum increases the bioavailability of the substance as opposed to vaping. But before the cannabidiol can take effect, it must first be processed through a line of CBD gummy equipment.

CBD gummies

To make candy, all you need to do is create a syrup by dissolving sugar and boiling it to your desired consistency. For medium to large scale candy production, candy making equipment fully automates the whole process and takes care of other production regulations and standards (such as hygiene and proper homogenization). Planning on getting one? There’s a wide range of choices to pick from.

Candy

Eating is more than just nutrition, but we have found ways to increase the nourishing power of our foods. Nutraceuticals manufacturing, from vitamin C powder and probiotics to omega 3 oil, is a concentration of natural ingredients and health supplements that complement our diets. While dietary supplements are not quite haute cuisine, the process of extraction and purification is no less a blend of science and art.

Nutraceuticals

One of the attractive qualities of cannabinoids is that they keep our stress responses in equilibrium. But for formulators of CBD gummies, preparing the

Two steps to stop formula deviation in CBD Gummies &#8211; Making.com

Two steps to stop formula deviation in CBD Gummies

Nathanael

With consumerism comes great responsibility. More and more are switching their diet towards vegan and vegetarian alternatives, varying from dairy to meat. As more plant-based meat technologies are being invented, the production is rising in popularity. Ever wondered which challenges come with that?

Plant-based meat

Sauces bring personality to a dish. From a spicy, dense Zhoug to a tangy, runny Suero, sauces add an extra dimension of flavor, texture, and mouthfeel. But developing recipes into industrial products with long shelf lives and consistent tastes is a complex process. Specialized sauce making equipment prepares and combines the ingredients into delicious, high-quality foods. The result is a sauce ready to elevate meals.

Sauce

Industrially manufactured soups gained traction in the 19th century when canning was invented and they have been warming us ever since. Whether it’s a classic ready-to-eat canned soup, condensed soup or a dry soup mix, soup manufacturing equipment for mixing, cooking, boiling, or sterilizing caters to every manufacturer’s production requirements.

Soup

<span style="font-weight: 400">Spice manufacturing is one of the world's oldest trading products. The word spice refers to any dried part of a plant other than the leaves and is used for seasoning and food coloring. Spices are made from dried barks, roots, berries, and twigs, while green leafy parts of plants are considered herbs. Well-known examples include cinnamon, chilies, star anise, ginger, garlic salt, turmeric, cumin, or pepper, as well as pre-mixed blends such as Masala, Five-Spice Powder, or Old Bay.</span>

Spices

If you have cooked vegan food before, you would know how difficult it is to recreate umami flavor only from vegetables. Luckily, Senson Oy came up with

#Changemaker: Fava bean umami extract for your vegan diet! &#8211; Making.com

#Changemaker: Fava bean umami extract for your vegan diet!

Hyunji Kim

Cheese is the most demanding food in the entire dairy family to emulate using non-animal and dairy free ingredients. The complex physical and taste profiles of animal-derived milk products make plant-based cheese manufacturing challenging to pull off. But the growing appetite for lactose-free and non dairy products is serving alternative platters of cheese.

Plant-based cheese

Drying meat was the prevalent method of conserving meat cuts when food could not be chilled. But dried meat products developed into delicacies and remained a culinary mainstay long after the functional need for preservation was answered with refrigeration. The ancient techniques have been replaced by dried meat processing equipment, but the time-honored recipes remain unchanged.

Dried meat

Edible oils are fats that you can extract from various plants and animal tissues. The most popular sources are olives and sunflowers. You can use them for different cooking techniques, such as frying, baking, and other methods. Manufacturers are now finding ways to extract oils with a higher natural fat content efficiently using edible oil extraction machines.

Edible Oil

In Greek mythology, the people of ancient Attica chose Athena as their patron after the goddess gifted them the first olive tree ever. The Athenians

#Changemaker: A divine alternative to synthetic preservatives &#8211; Making.com

#Changemaker: A divine alternative to synthetic preservatives

There is an area at the southern tip of Africa called Cederberg mountain, which is one of a kind. Do you know why? Cederberg mountain is the only place

#Changemaker: Discovering the Rooibos plant applications &#8211; Making.com

#Changemaker: Discovering the Rooibos plant applications

Deborah

A freeze dryer for herbal medicine holds the promise of preserving the essence and can be interesting investment for farmers and traders.

Herbal medicine uses natural sources as a possible source of drugs. More than 80% of people worldwide relies on it for some part of primary healthcare.

The careful drying of herbal medicine &#8211; Making.com

The careful drying of herbal medicine

We are happy to share our knowledge on making pharmaceuticals and nutraceuticals. Send us a message and we will help you solve your production challenge.

Plant extracts purification

Which plant extracts purification equipment do you need?

Short path evaporators

Laboratory short path distiller

Laboratory wiped film distiller

Laboratory multi-stage distiller

Pilot short path distiller

Pilot wiped film distiller

Pilot multi-stage distiller

Wiped film evaporator

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