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Cannabinoids distilling

Cannabis seeds

Gummies make everything more colorful. The squishy droplets make a tasty and practical carrier of special ingredients such as CBD oil. Chewing the gum increases the bioavailability of the substance as opposed to vaping. But before the cannabidiol can take effect, it must first be processed through a line of CBD gummy equipment.

CBD gummies

While still forbidden in many countries, there's plenty of room for the use of cannabidiol, or CBD. It’s the second most present active ingredient of the cannabis plant and, no, it won’t get anybody high. What it does, really, once it’s out of the CBD oil processing equipment, is to provide many well-being and health benefits. They go from treating depression and anxiety to relieving pain and unmanageable diseases' symptoms.

CBD oil

Softgel capsules fast-track the delivery of medication to the bloodstream. Unlike solid pills, they do not need to be broken down by the body before the drugs can be absorbed. Moreover, they are optimal vehicles for oils and fat-soluble formulations that cannot be compressed into tablets.

Softgel capsules

The cannabis industry is one of the fastest growing in the world with a revenue of $20.47 billion in 2020 which is expected to soar up to $197.74 billion in 2028. The famous cannabis substance that causes marijuana's psychological effects is THC and it was first isolated in 1964. There are two methods of extracting THC from cannabis: solvent-based and non-solvent extraction. Each technique requires different THC oil extraction equipment.

All plastics are polymers, but not all polymers are plastics. Polymer production is a multi-step process that transforms raw materials into products that we use in our day-to-day life with the help of polymer process equipment such as extruders, calenders and injection molding machines.

Polymers

Nut oil

Fish oil was a folk remedy long before scientists identified the nutritional value of essential fatty acids. But Omega 3 processing has come a long way since the days of raw fish parts fermenting in a barrel. In fact, new supplement formulations of polyunsaturated fatty acids (PUFAs) may not use fish at all.

Omega 3 oil

The rapeseed flower evolved high concentrations of substances that are anti-nutritive at best and toxic at worst. But new varieties developed in the 1970s lowered the content of glucosinolates and erucic acids. From then, the use of oilseed rape spread to several applications, from edible oil to biofuel to animal feed. Rapeseed oil processing technology has thus become foundational to industries spanning food production, energy, cosmetics, and pharmaceuticals.

Rapeseed oil

Everything tastes like porridge, the saying goes. That may be an exaggeration, but in theory, reaction flavors could make everything taste the same. Thankfully, flavorists and chemists in the flavor industry are more inventive than that, and colorful process flavors treat our taste buds to a broad palette of sensations, flavors and aromas.

Reaction flavors

Can process temperature sensitive high boiling products

Can handle viscous and fouling products

Configuration based on customer's requirement is possible

Short Path Distillers

Wiped film distillers

Chemical

Food

Pharmaceutical

Industrial Distillation Equipment

Industrial distillation equipment is used in the process of separating different constituents of a liquid mixture. Considerations for choosing suitable distillation systems include the boiling points of the components, heat sensitivity of the product of interest, pressure requirements during the process, and the scale of production. Distillation is used for concentrating extracts such as herbal extracts, flavors, and aromas in the food industry. In the pharmaceutical industry, distillation is used in the production of active ingredients and in the chemical industry for the purification of chemical products.

Distillation

Find industrial distillation equipment to set up your production line and connect directly with world-leading machine and equipment manufacturers.

Distillation &ndash; Making.com

Industrial Distillation Equipment - Making.com

Biopharmaceuticals are drugs in which the active substance is manufactured or extracted from biological origin materials. They are usually produced in bioreactors by plant cells, microbial cells, yeast cultures, or mammalian cells. Also known as biomanufacturing, they are used to either treat or diagnose and prevent a patient’s medical condition or disease. Biopharmaceuticals are typically complex macromolecules administered by injection or infusions, and examples include vaccines, serums, and insulin.

Biopharmaceuticals

Cannabinoids are natural compounds obtained from the Cannabis sativa plant. Delta-9-tetrahydrocannabinol or THC is a psychotropic substance. Cannabidiol, or CBD, is non-psychotropic and often used for nutraceutical purposes. Cannabinoid equipment extracts THC and CBD from the plant and prepares the substance for formulations that treat pain, nausea, anxiety, and inflammations. Cannabinoids are processed in various forms, including creams, capsules, and oils.

Cannabinoids

Due to their potential hazardous nature, chemicals are classified for proper identification and safety during production. Chemical classification depends on their properties, structures and functions. In the chemical industry, you can regard them as basic chemicals such as acids, chemical products to produce plastic materials and finished chemicals for use in cosmetology. As a manufacturer or engineer, you want to know their reactivity when using chemical processing equipment.

Chemicals

Essential oils are known as the liquid gems of nature. The sweet-smelling essences impact not just our senses but also our biochemical and cellular make-up. Besides aromatherapy, the products of an essential oil extraction system found applications in pharmaceuticals and foods.

Essential oil

Our food chain starts in the soil, growing crops and livestock. But between the fields and the stores, there is a line of industrial food processing equipment. Processes may be as minimalistic as cleaning fruit and as complex as homogenizing milk alternatives made from pressed legumes. In each case, processing technology is an important link in the food production chain.

Pharmaceutical developments walk side by side with health advances to provide new medicines, treatments, and therapies that have increased life quality and extended life expectancy by years. Pharmaceutical manufacturing equipment helps deliver products to a great deal of the population, but there’s a significant share that doesn’t benefit from them yet. Over 2 billion people cannot get the medicines they need, according to the United Nations Industrial Development Organization, and local production might be a way to provide for these people.

Pharmaceuticals

Ancient civilizations discovered that plant extracts were useful for the treatment of pathologies. The origin of plant extraction cannot be specifically verified, but we can infer that the earliest attempts at plant extraction were more intuitive than scientific. Today, the extraction of compounds is a precise process with plant extraction systems complimenting traditional knowledge.

Plant extracts

Can it be said that we live in the Plastic age? Basically, yes. From pillows over toothbrushes, and packaging to utensils, plastic is a widely used material in our day-to-day lives. But what is it? Plastics are synthetic or semi-synthetic materials built of polymers that are easily shaped into various structures with the help of plastic processing equipment such as extruders and molders.

Plastics

Process

R&amp;D

Continuous

Purification is the removal of contaminating substances and by-products to increase the level of purity of the desired substance. Considerations for choosing a suitable purification system in the industry, include the physical state of the mixture, the desired product, required level of purity, the type of mixture, heat sensitivity of the product, number of purification steps needed, and the production volume. Industrial purification systems are used for the production of pure water in the food pharmaceutical and biotech industries.

Purification

Industrial separation equipment encapsulates the separation process which is to separate components of a liquid mixture, for recovering dissolved solids from liquids. The choice of a suitable technology depends on the identification of the key physical or chemical property, such as size, mass, density, or boiling point, which sets the product of interest apart from the rest of the components. Separation technology is widely used in the pharmaceutical and chemical industries for the isolation of active ingredients and high-purity chemicals. As well as in waste management and recycling industries.

Separation

liquid

Pilot multi-stage distiller combines short path and wiped film distillation methods to helo you achieve the quality of your product.

If generating an scalable data and bring in results with small sample quantities of high-boiling, heat sensitive and highly viscous products using a short

Pilot multi-stage distiller &ndash; Making.com

We open production technology to everyone

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The humble chamomile flower holds a rich blend of compounds that soothe body and mind. A natural antidepressant and anti-inflammatory, chamomile oil found its way into the earliest pharmacopeia. As more of its properties were discovered, the oil became an elemental ingredient for a vast range of pharmaceutical and cosmetic recipes. Chamomile oil processing equipment developed at the same speed, offering manufacturers multiple production techniques to extract the liquid from the precious flower.

Chamomile oil

Elderberry falls squarely in the category of superfoods. Every part of the plant (flowers, berries, and bark) is loaded with vitamins, antioxidants, bioflavonoids, and other compounds. However, cyanide in the plant could be lethal if consumed raw, making elderberry extraction processing complex.

Elderberry extract

Only one percent of the entire plant species on the planet produces essential oils, but that amount has found its way into various products, from perfumes to foods. Flower extraction systems are similarly diverse, and picking the right ones depends on the organic material and the final product.

Flower extract

What’s the only living connection between our present world and the age of dinosaurs? The ginkgo biloba plant. Also known as the maidenhair tree, it is regarded as a living fossil and has been around for more than 200 million years. Ancient civilizations in China were already mastering ginkgo processing centuries ago and the tradition soon flourished around the world.

Ginkgo extract

Lavender oil is one of the most common essential oils in the market currently. Extracted from the herb Lavandula spp., this essential oil is used as a complementary medicine and as an additive. Studies have shown that lavender oil has sedative, carminative, anti-depressive, and anti-inflammatory properties. Like other essential oils, lavender oil extraction equipment must be capable of distillation, condensation, collection, and separation processes.

Lavender oil

The ancient Greeks believed feeding sea buckthorn to their horses would give them a lustrous hide. Indeed, full of lipids and carotenoids, the fruit did contribute to glowing, reddish coats. However, the thorny plant also has benefits for humans. Sea buckthorn processing equipment extracts this unique vegetable oil full of fatty acids. The liquid is a prominent component in various food, cosmetic, and pharmacological preparations.

Sea buckthorn oil

Tea tree oil, also known as melaleuca oil, is an essential oil with immune system stimulants produced mainly in Australia. The tea tree oil manufacturing process starts from the leaves of Melaleuca alternifolia. In terms of market value, the one for tea tree oil was valued at 38.8 million USD last 2017 and is projected to increase to 59.5 million USD by 2025.

Tea tree oil

Processing of high-boiling, high-viscosity or crystallizing product are possible

Can be operated at pressure range of 0.1 mbar to 1,000 mbar

Can be combined with additional evaporation stages

Pilot wiped film distiller units are used to process small product quantities that will enable a later scale up to an industrial system.

Generate scalable data and results during the pilot tests with wiped film distillation,  distill or dry of small product quantities with as little as 30

Pilot wiped film distiller &ndash; Making.com

Koala bears diet exclusively on eucalyptus leaves. But the large concentration of cineole in the tree keeps most other predators at bay. Humans, though, discovered ways to extract the substance and use it as a remedy against inflammations and other diseases. The eucalyptus oil production process keeps evolving to maximize yields, ensuring enough eucalyptus forests for koalas.

Eucalyptus oil

Rose oil is an essential oil extracted from the petals of either Rosa damascena and Rosa centifolia. Also known as liquid gold, rose oil production originated from Greece and is currently manufactured mainly in Bulgaria, Turkey, and Morocco. Studies have shown that rose oil has medicinal properties, exhibiting anti-inflammatory, anti-infective, and wound healing actions.

Rose oil

Can be operated at pressure range of 0.001 mbar to 1,000 mbar

Can handle highly viscous material with max. viscosity of 15,000 mPas (cP)

Products with high boiling points at 0.001 mbar can be evaporated

Pilot short path distillers are set up as modules and used to separate small product quantities that will enable a later scale up to an industrial system.

Generate scalable data and results during the pilot tests with short path distillation, distill or dry of small product quantities with as little as 30 kg

Pilot short path distiller &ndash; Making.com

Panax ginseng is a medicinal plant with a long history steeped in myth. The term “panax” itself is derived from a Greek word for “panacea” or “cure all”. As ginseng processing technology continues to develop, this famous traditional extract keeps finding new applications.

Ginseng extract

Mineral water is mother nature’s cocktail of dissolved solids. The concentration of essential chemicals in the water makes it an excellent source of nutrients and electrolytes. Although your bottled product retains most of the properties present at its natural condition, the water still needs some help before it can be safely consumed.

Mineral water

Can be configured based on customer's requirement

PLC and visualization option can be selected

Batch

The VTA Laboratory multi-stage distiller is a combination of the short path and wiped film distillation technique.

A laboratory multi-stage distillers that combines the wiped film and short path distillation technique allows you to test the separation of high-boiling,

Laboratory multi-stage distiller &ndash; Making.com

Oleochemicals

Provides visual observation of the distillation process

Proper and reliable tests can already be performed with 2 kg of crude material

Can handle material with max. Viscosity of 15,000 mPas (cP) at operating temperature

Options of continuous feeding systems and continuous discharging systems for distillate and residue can be selected

The VTA wiped film distillation laboratory unit is designed to distill small product quantities for acquiring reliable data of the separation process.

Reach reliable conclusions testing the distillation of high-boiling or highly viscous material using as little as 2 kg of crude material. Small scale

Laboratory wiped film distiller &ndash; Making.com

Echinacea, also known as coneflowers, are brightly hued flowers with distinguished, cone-shaped flower heads. Over 200 medicines in the world are derived from coneflower extracts. Echinacea processing was introduced by Native Americans who were interested in the plant's medicinal qualities.

Echinacea extract

A variety of size selection is available based on customer's requirement

Continuous feeding systems and continuous discharging systems for distillate and residue options can be selected

The VTA Laboratory short path distiller integrate the short path distillation technique and are set-up as modules.

Get to reliable conclusions for the separation of high-boiling and heat-sensitive products using as little as 2 kg of crude material. Small scale thermal

Laboratory short path distiller &ndash; Making.com

Find extraction solutions

The Cannabis sativa goes through a complex process after harvest. Specialized cannabinoid equipment chops the plant in preparation for gentle drying. Solvent extraction techniques using ethanol or supercritical fluids produce crude cannabis oil. But this requires further purification.

Distill the substance to <a href="https://making.com/thc-extract" target="_blank" rel="noopener">separate THC</a> from terpenes, lipids, impurities, and solvent residues. Finally, treat the cannabis isolate with a homogenizing system to break down the bonds and reduce the size of CBD particles.

Go for cannabinoid equipment that delivers gentle extraction 

<h3>Apply cold ethanol extraction to shorten the process stages</h3>
One method of CBD solvent extraction uses ethanol at a temperature of -40° C. In contrast to other techniques, this does not need a pressurized system. Feed the cold ethanol directly into the extraction equipment with the cannabis biomass.

The solvent forces the volatile compounds out of the plant, leaving behind the lipids. By removing the need for winterization, solvent recovery, and decarbing, cold ethanol extraction minimizes the cannabinoid equipment line and the process.

THC levels of distilled oils must be decreased to meet the thresholds defined by regulatory bodies. For instance, most EU countries impose a THC content limit of 0.2% in CBD products, including edibles such as <a href="https://making.com/cbd-gummies" target="_blank" rel="noopener">CBD gummies</a>.

Purified CBD extracts must be filled using sterile systems and deposited in sealed formats, whether capped jars or pouches. Another essential equipment category in cannabinoid production is labeling machines with serialization functions.

Decrease the THC content according to market requirements

Starch can lead to bacterial growth, and many jurisdictions restrict its use for molding. But <a href="https://making.com/stories/tech-is-was-keeping-vitamin-gummy-manufacturers-from-cutting-starch" target="_blank" rel="noopener">starchless depositing equipment</a> for CBD gummies has more advantages than contamination-free products.

The gum syrup takes much less to dry in the molding trays than by moisture absorption from starch. Moreover, starchless depositing produces high-definition shapes and a better yield from demolding.

Remove starch from CBD gummies

<h3>Formulate CBD oil products with other ingredients</h3>
CBD oil for medical treatment is dispensed in dosage forms such as <a href="https://making.com/ampoules" target="_blank" rel="noopener">ampoules</a>, syringes, and capsules. Filling medicinal dosage utensils requires cannabinoid equipment to meet GMP standards made from materials like 316L grade stainless steel or PTFE.

<a href="https://making.com/cbd-oil" target="_blank" rel="noopener">CBD oil formulations</a> are typically mixed with other ingredients like olive oil and terpenes. End products base the extract ratio on the target medicinal potency of cannabinoids per dose determined by pharmaceutical requirements.

Making Cannabinoids

Find industrial systems for for extracting, purifying, and processing cannabinoids and connect directly with leading technology suppliers.

Cannabinoids &ndash; Making.com

Find equipment for making Cannabinoids &ndash; Making.com

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Traditional extraction processes involving hot solvent (ethanol) or Co2 may produce varied results in the mass production of CBD oil. Moreover, the cannabidiol extraction process takes several days to complete, reducing the plant's output capacity. With a growing market for CBD products, companies need to produce high-quality materials consistently at a faster pace.
<h2>Save time with a continuous extraction system for CBD oil</h2>
Devex’s CryoEXS is a time-efficient solution to extract crude CBD oil from cannabis or hemp. It uses cold (-40 C) Ethanol as a solvent to extract useful substances. The equipment is available in 3 sizes depending on the capacity of dry cannabis biomass throughput.

The dried cannabis is fed into the extractor simultaneously with the cold ethanol. This method helps avoid the extra 24 hours of extraction process needed for the winterization step used in traditional methods to eliminate undesired elements from the extract such as fats, waxes, pigments, etc. Additional cannabinoid losses that can occur during the winterization step are also avoided.  Then the mass is recirculated to achieve a highly efficient extraction. The crude CBD oil is then ready for short part distillation. The ethanol used in the extraction process is then sent back to the tank for purification and reuse.

Learn more about CBD oil extraction <a href="https://making.com/cbd-extraction-equipment/">here</a>.

Fully certified CBD crude oil extraction machine

Find out how trichome color can help you understand whether or not your cannabis plant is ready for harvest.

When producing CBD oil, it is not only crucial to choose the right extraction method (supercritical CO2 extraction or cold ethanol extraction), but also

How cannabis harvesting affects the quality of your final extract? &ndash; Making.com

How cannabis harvesting affects the quality of your final extract?

Irina Lescika

While CBD's popularity grows every day with its medical benefits always in the spotlight, not everyone knows that CBD extraction also involves a waste

How to create less waste when extracting CBD oil &ndash; Making.com

How to create less waste when extracting CBD oil

Deborah

Over the last few years, CBD has been actively used for medical purposes, to address anxiety, and for patients who suffer through the misery of insomnia.

The value of GMP certification when making CBD products &ndash; Making.com

The value of GMP certification when making CBD products

Full Spectrum, CBD Isolate and Broad Spectrum: What is the difference between the three types of CBD oils?

Several studies show that almost 62 percent of consumers use CBD to treat medical conditions, like pain, anxiety, and depression. In pharma, CBD products

Which type of CBD oil could you make? &ndash; Making.com

Which type of CBD oil could you make?

We are happy to share our knowledge on making pharmaceuticals and nutraceuticals. Send us a message and we will help you solve your production challenge.

IndustryExpertPharma

There are few methods to extract CBD oil from cannabis plant that are considered safe to use for consumers products: supercritical CO2 extraction or

Cryogenic ethanol for CBD oil extraction &ndash; Making.com

Cryogenic ethanol for CBD oil extraction

When processes call for homogenized emulsions with extremely fine particle sizes the traditional toothed ring dispensers are not always sufficient.  For extremely high levels of disintegration required to produce true micro-emulsions, extreme pressure cycling is more successfully used.
<h2>Homogenization with pressure shock to achieve extremely small particle sizes</h2>
The HPH High Pressure Homogenizer from IKA uses one or more piston pumps to apply pressure up to 2000 bar to the liquid medium to be homogenized.  The fluid is then fed through a homogenizing valve which very quickly reduces the pressure to the atmosphere.  This abrupt change in pressure in the moving fluid causes cavitation, a high degree of turbulent flow, and internal shearing forces in the fluid all of which serve to break up and distribute larger particles forming a very fine emulsion.  The pressure applied on the uphill side of the homogenizing valve is infinitely adjustable as is the flow rate through the valve, so the process can be easily adapted to achieve a wide range of outcomes and to accommodate fluids with different flow characteristics.  All parts that contact the product flow are stainless steel and autoclavable and the entire unit is designed for robustness and long service life.

High-pressure homogenizer

Thomas Jefferson, the third U.S. President once said, "Hemp is of the first necessity to the wealth and protection of the country." He said this  because

CBD oil production to achieve a new 'high' &ndash; Making.com

CBD oil production to achieve a new &#8216;high&#8217;

After threshing seeds from plant material, various cleaning steps still have to be done to ultimately have clean seed. This machine does all of these steps in one process. This makes this machine ideal for breeding stations, plants can also be threshed one by one.


<h2>Damage-free threshing of seeds</h2>
Manufactured by Seed Processing Holland, STM-350 is a seed thresher that’s suitable for processing stock seed productions and breeding stations. It threshes vegetables seeds, field crops and <a href="https://making.com/hemp-seeds/">the hemp seeds</a> out of pods, umbels and buds without damaging them.

Operators need to manually feed the plants into the machine using the inlet table, where the pods and umbels are then broken down into smaller pieces with three polyurethane beaters. Since the beaters are constructed with polyurethane, they’re able to withstand strong forces.

The speed and the distance between the threshing basket and beaters can further be easily adjusted according to specific user requirements. Once the threshed seeds go through the threshing basket, they’re processed on a shaking screen, which sorts the seeds into one overflow and lower fraction. The overflow fraction is emptied into an anti-static bin, while the remaining seeds are moved to the air separator to be separated into heavier and lighter parts.

Once the seeds are separated from the pods or umbels, the good and heavy ones are collected in an anti-static bin. Lastly, STM-350 is designed with numerous clear polycarbonate windows, enabling operators to visually inspect and adjust the process wherever necessary.

Seed threshing machine

The quality of seeds and grains starts to deteriorate once they have been harvested. Thus, it’s essential to remove the impurities and dirt as soon as possible to ensure a high-quality product for end-users. In order to optimize seed quality, it’s advisable to pass them through an Air screen seed cleaning machine. However, a few machines can properly remove impurities, damaged particles, and dirt from seeds.


<h2>Separates impurities and ensures proper pre-cleaning of seeds</h2>
Manufactured by Seed Processing Holland, the <a href="https://making.com/equipment/seeds-blowing-machine-for-separation/">Air Screen Cleaning Machine cleans seeds</a> by separating dust, empty seeds, chaffs, and weeds. Its frame is constructed with steel, while its screen boat is designed with water-resistant wood to ensure longevity, durability, and reliability.

The screen boat can fit three screens, and each screen features a quick closing and opening system. The screens are also easily exchangeable, making the unit easy to clean and safe from seed contamination.

Moreover, it continuously cleans the screens to prevent clogging. Finally, the machine separates the waste and seeds into five different fractions, with the air channel removing dust, chaffs, and dirt from the seed. The air channel is further designed with a glass window, enabling operators to see the separation process.

Lastly, the capacity of the Air Screen Cleaning Machine depends on the type of seed and can range from 10 to 200 kg per hour.

Air screen seed cleaning machine

Hemp, as a plant, can be used to produce textiles, organic compost, fuel, and even food. The main processes of the hemp seed are sieving, grading, and dehulling or removal of the shell that covers the seeds. For these processes to happen, hemp farmers will need suitable processing equipment. These seeds can be used to create an oil with a by-product known as hemp cake or hemp meal. This by-product is used as a base substance for producing hemp protein powder. It is due to these by-products that the hemp industry is constantly growing globally.

&nbsp;

Hemp seeds

Feed

Whether for personal consumption or agricultural purposes, you process seeds to make them clean and maximize yield. Seed processing equipment includes the steps of polishing, threshing, separation, sorting, and drying. Some cases require additional processes. For example, the extraction of the seed from fruits or vegetables. Or, pressing the seed to extract oil.

Seeds

Hemp seed-based products have become a popular alternative source of protein for vegetarians and vegans. Hemp protein and hemp flour are considered as

How to separate seeds from hemp crop &ndash; Making.com

How to separate seeds from hemp crop

We are happy to share our knowledge on making different food products. Send us a message and we will help you solve your production challenge.

Foodie

Eating is more than just nutrition, but we have found ways to increase the nourishing power of our foods. Nutraceuticals manufacturing, from vitamin C powder and probiotics to omega 3 oil, is a concentration of natural ingredients and health supplements that complement our diets. While dietary supplements are not quite haute cuisine, the process of extraction and purification is no less a blend of science and art.

Nutraceuticals

Hemp as one of the most versatile plants is widely used to produce a variety of products, from papers and textiles using hemp fibres to hemp protein and flour.

Hemp as one of the most versatile plants is widely used to produce a variety of products, from papers and textiles using hemp fibres to hemp protein and

Freeze drying microencapsulated hemp seed oil &ndash; Making.com

Freeze drying microencapsulated hemp seed oil

Find production technology for Cannabinoids distilling, and connect directly with leading machine manufacturers worldwide.

Cannabinoids distilling

Which cannabinoids distilling equipment do you need?

Pilot multi-stage distiller

Pilot wiped film distiller

Pilot short path distiller

Laboratory multi-stage distiller

Laboratory wiped film distiller

Laboratory short path distiller

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