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Equipment For Bioprocessing Dairy Products Equipment

People have always loved butter. Suffice it to say that Ancient Norsemen were buried with it to take to the afterlife. It seems impossible but making butter is all about separation. First, you separate the raw milk to get the buttercream using a cream separator. After cooling, mixing and pasteurizing your buttercream, the churning process separates it into buttermilk and butter grains. Then, mix butter grains with salt and use a butter churner to mix the ingredients again, before shaping begins using butter molds. Which butter-making equipment can improve your process?

Butter

Can you think of anything better than a slice of bread with some spreadable cheese for a snack? Production of cheese spread is similar to other types of processed cheese, but it contains more moisture to be soft and spreadable. Cheese spread starts with one or more types of cheese along with other ingredients and food additives such as stabilizers and emulsifiers. After mixing and vacuum cooking these ingredients, you can pour them into molds for cooling before packaging.

Cheese spread

To produce condensed milk, you need to remove a large portion of the water content from the milk. Usually, you add sugar to it to create a sweet flavor. First, milk is standardized and pasteurized. Then, it goes through an evaporation process to remove the excess water content while sugar is added. After that, the mixture undergoes homogenization. The condensed milk is cooled and crystallized before being ready for packaging.

Condensed milk

Curd

You usually make grated cheese from hard cheeses, like Cheddar, Parmesan, Edam, Red Leicester, etc. The process starts with processed cheese, in blocks or sliced, fed to the grating machine. After that, you mix it with ingredients that prevent molds from occurring and to reduce the grated cheese moisture. Then you dry the grated cheese and weigh it before it is ready for packing.

Grated cheese

Aphrodite’s Rock, the Limassol Carnival, and the Tomb of the Kings are defining features of Cyprus. But perhaps nothing characterizes the Mediterranean island as well as halloumi. The salty, springy cheese has been a staple of Cypriot homes for centuries. But halloumi production technology is now bringing this delicacy to others far away from the region.

Halloumi

Making ice cream is all about mixing and homogenizing. First you need to blend, pasteurize and standardize your mixture. Then store it in tanks and freeze and aerate the mix until it reached the right consistency. Now you can add fruits, cookies and other solids if you like. In the final step the mix goes through an air blast hardening machine and it's ready to store and ship.

Ice cream

Margerine

Basically, to make milk powder, you need to remove the water content from the liquid milk and turn it into powder. How to do it? After pasteurizing and homogenizing the milk, milk’s water content is removed through filtration, evaporation, and drying. You have then to cool and sieve it before filling the containers. Here's how you get milk powder.

Milk powder

Mozzarella

Cheese is the most demanding food in the entire dairy family to emulate using non-animal and dairy free ingredients. The complex physical and taste profiles of animal-derived milk products make plant-based cheese manufacturing challenging to pull off. But the growing appetite for lactose-free and non dairy products is serving alternative platters of cheese.

Plant-based cheese

Whey

After pasteurizing and homogenizing the raw milk, you need to ferment the milk with starter culture until solid curds and liquid whey is formed. Then, the liquid whey goes through a filtration and drying process to turn it into powder. Before sending it to packaging, flavorings are usually added.

Whey protein

Neige de lait in French or neve di latte in Italian, as referred to in very old texts and both meaning milk snow, has been used in recipes since the 15th century. Withstanding the test of time, whipped cream is still one of the most beloved dessert toppings. What starts with milk ends as a silky delicacy with the help of whipped cream equipment and specified manufacturing processes.

Whipped cream

Yogurt makers start with raw milk from animals like cows and goats and produce yogurt by standardizing milk, reducing fat content and increasing total solids before pasteurizing to remove harmful bacteria. After pasteurization, the milk undergoes homogenization to make it smoother and more consistent. The milk then receives yogurt cultures, and the product undergoes a fermentation process. Finally, you can cool and refrigerate the yogurt and prepare it for packing.

Yogurt

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Salad dressing has found its way onto dinner plates for millennia as a quick way to liven up leafy dishes. Experimentation with oil, vinegar, wine, salt, and other ingredients developed into the broad selection of dressings we enjoy today. Through a process of emulsifying the basic formula, adding additional elements, and then bottling and labeling the final mixture, consumers have easy access to reliable tastes on demand.

Salad dressing

Cell culture has been, over a little more than 100 years, an important method of research in laboratories. But medicine developments aside, we wonder if even the most positive of idealists could have also believed that cell cultures and tissue culture would possibly change the way – and what – we eat. From the lab to the dining table, there’s cell culture equipment to make even the unimaginable possible.

Cell cultures

You can make emulsions by combining two immiscible liquids (oil and water, for example) in a suspension through the use of force. The use of emulsifiers is necessary to keep this mixture stable and permanent.

Emulsions

All plastics are polymers, but not all polymers are plastics. Polymer production is a multi-step process that transforms raw materials into products that we use in our day-to-day life with the help of polymer process equipment such as extruders, calenders and injection molding machines.

Polymers

Ketchup processing begins with tons of tomato paste that is mixed and heated together with sugar, vinegar, and spices in a cooking kettle. After cooking, any remaining fibers and particles are filtered out. Once it reaches the right viscosity, your tomato ketchup production process is finished and ready for packaging and transport.

Ketchup

Although invented in the 1990s by Rickard Öste, oat milk has only recently grown to be one of the most popular milk alternatives in coffee shops, and it owes it to its smooth mouthfeel and creamy texture. Extracted the plant materials from oats with water, this non-dairy milk is high in fibers, low in saturated fats, and eco-friendly. Oat milk processing equipment helps prepare raw materials, starting with harvest over kilning and making them into flakes or flour, and mixing the prepared materials with water and enzymes.

Oat milk

First mentioned on a stone slab of the Eastern Han dynasty in ancient China, soy milk has survived centuries and spread from Asia to Global consumption due to the rising popularity of plant-based alternatives. To produce soymilk, raw materials must be harvested, prepared, and blended with water and desired ingredients, such as flavors and vitamins, in soymilk processing equipment.

Soy milk

Easy to clean and maintain, minimal downtime

100% scalability guarantee

Cost-effective electric power

Adjustable pressure to 45,000 PSI

Highest process intensity in the industry

Sampling is the process of aseptically drawing a sample from the process for analysis, without disturbing the bioprocess itself. The bioprocess needs to be carefully controlled by measuring important process variables and parameters. These parameters include pH, temperature, dissolved oxygen, foam/level, and agitation. The controllers use PID or auto-tuning adaptive control to measure and regulate the process parameters. The choice of a suitable controller depends on the identification of critical process variables.

Biotech sampling and control

Continuous milling is a flow production method used to grind materials without interruption. It is often used in the production of foods, cosmetics, pharmaceuticals, chemicals, and minerals. The material to be processed flows in at one end and the milled output flows out at the other in a continuous process. By choosing the right combination of milling technology and processing power you can obtain the desired particle size distribution in an uninterrupted stream.

Continuous milling solutions

High-pressure homogenizers are used in bio-pharmacy applications to obtain intracellular components like enzymes and proteins from bacteria, fungi, and animal cells through cell rupture. They are also used in other biotech processes such as the production of nanoparticles for tissue engineering and in the development of new drugs, vaccines, antibiotics, and chemicals. The choice of a high-pressure homogenizer depends on the mixture to be processed, desired particle size distribution, and the type of force to be applied to the particles.

High pressure homogenizers

Research and development work often requires the production of small and ultra-small batches. Laboratory mills allow limited production of experimental batches without the need for interrupting work on production machines. Typical applications of laboratory mills include new product development, process improvement, and quality control work. The choice of a suitable laboratory mill depends on your milling technique requirement, the batch size range, and the nature of the product that needs to be processed.

Laboratory mills

Chemical

Cosmetic

Food

Pharmaceutical

Biotech Equipment

Biotech equipment is used for cellular and biomolecular processing to develop products that improve our lives and the planet. With the help of specialized lab equipment, the active substance is manufactured or extracted from biological origin materials and typically produced in bioreactors by plant cells, microbial cells, yeast cultures, or mammalian cells. Cell isolation, cultivation, cell banking, and culture expansion are called upstream processes. After harvest, the production process moves into a downstream process to meet purity and quality requirements which is divided into cell disruption, purification, and polishing. Biotechnology equipment makes use of various laboratory machinery such as bioreactors, centrifuges and incubators.

Biotech

Connect directly with world-leading manufacturers of biotech equipment and improve or set up your biotech production process.

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Biopharmaceuticals are drugs in which the active substance is manufactured or extracted from biological origin materials. They are usually produced in bioreactors by plant cells, microbial cells, yeast cultures, or mammalian cells. Also known as biomanufacturing, they are used to either treat or diagnose and prevent a patient’s medical condition or disease. Biopharmaceuticals are typically complex macromolecules administered by injection or infusions, and examples include vaccines, serums, and insulin.

Biopharmaceuticals

Due to their potential hazardous nature, chemicals are classified for proper identification and safety during production. Chemical classification depends on their properties, structures and functions. In the chemical industry, you can regard them as basic chemicals such as acids, chemical products to produce plastic materials and finished chemicals for use in cosmetology. As a manufacturer or engineer, you want to know their reactivity when using chemical processing equipment.

Chemicals

According to a legend, Cleopatra soaked her sails in her perfume so that Mark Antony could smell her ships before they arrived. This is to say that, from soaps and shampoos to perfumes, conditioners and pomades, cosmetics have always been highly valued and used for their properties of aesthetic enhancement. Cosmetics are a broad class of topical agents applied for various purposes such as cleansing, protecting, beautifying, or otherwise altering your appearance. As a result, a wide array of processing equipment is used in the cosmetics industry.

Cosmetics

The topical route is a convenient route for the self-administration of drugs. But turning a pharmaceutical formulation into an easy-to-use cream involves specialized cream manufacturing equipment. Topical dosage forms are essentially an emulsion of oil and water.  But the ratios can be changed to process it into lotions, ointments, and gels.

Cream

Milk can be consumed as a stand-alone product (whole, low-fat or skim) or can be the starting point for food industry products such as cheese, butter, yogurt, condensed milk, and ice cream. In order to process milk and other dairy products, you need specialized dairy production equipment which then encapsulates different processes such as pasteurization, homogenization, and fermentation.

Dairy

Our food chain starts in the soil, growing crops and livestock. But between the fields and the stores, there is a line of industrial food processing equipment. Processes may be as minimalistic as cleaning fruit and as complex as homogenizing milk alternatives made from pressed legumes. In each case, processing technology is an important link in the food production chain.

Pharmaceutical developments walk side by side with health advances to provide new medicines, treatments, and therapies that have increased life quality and extended life expectancy by years. Pharmaceutical manufacturing equipment helps deliver products to a great deal of the population, but there’s a significant share that doesn’t benefit from them yet. Over 2 billion people cannot get the medicines they need, according to the United Nations Industrial Development Organization, and local production might be a way to provide for these people.

Pharmaceuticals

With the right processing machines, almonds, cashews, pine nuts, hemp, coconut, oat and soy can be processed into healthy plant-based milk. To produce it, grind the raw materials, screen, soak and mix them till you obtain a milky white liquid.

Plant-based milk

Sauces bring personality to a dish. From a spicy, dense Zhoug to a tangy, runny Suero, sauces add an extra dimension of flavor, texture, and mouthfeel. But developing recipes into industrial products with long shelf lives and consistent tastes is a complex process. Specialized sauce making equipment prepares and combines the ingredients into delicious, high-quality foods. The result is a sauce ready to elevate meals.

Sauce

Process

R&amp;D

Continuous

Formulation technologies are an integral process in many industries such as pharma and food. Chemical mixtures require strict handling to combine the separate ingredients into the homogenized recipe that makes your final product. Formulation technology stores, mixes and subjects the elements to a range processing parameters according to your specifications to develop the base material. The resulting formulas are then weighed, formed, packaged, or sent for further formulation.

Formulation

Homogenization is the process of reducing particle size in mixtures to improve the consistency, uniformity, and stability of the product. The choice of a homogenizer depends on the nature of the product, desired particle size, the physical state of the ingredients, and pressure requirements during the process. Homogenization is widely used in the biotech industry for cell lysis and in the pharmaceutical industry for the emulsification of creams and ointments; it also finds applications in the cosmetics and food industries for improving the consistency and uniformity of various products.

Homogenization

Milling machines are used to reduce the size of material by cutting, crushing, or grinding it. The choice of industrial milling equipment depends on the industry and the materials to work with. Besides, there is a significant difference between those aimed to remove layers from metal or other materials workpieces and those designed to reduce particle size for materials that come in bulk.

Milling

Industrial mixing equipment is used to combine two or more solid, liquid or gaseous segregated ingredients into a homogenous single product. The choice of mixing technology depends largely on the physical state of the ingredients and the desired final product. But the sensitivity of the ingredients, the process temperature, and pressure requirements are also critical factors. All these parameters result in a wide range of industrial mixers.

Mixing

liquid

solid

For maximum value, a high-pressure homogenizer that’s suitable for both laboratory and pilot/small scale pharmaceutical production is the ideal choice.

Pilot high pressure homogenizer - Making.com

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Cosmetic serums are a very light formulation with a high density of active ingredients dispersed in oil, water, or gel. This makes serums well suited to the delivery of vitamins, antioxidants, and anti-aging ingredients, but provide less moisturization and protection. Serum production is mainly divided into stages related to optimal mixing and preventing degradation of the active ingredients.

Serums

Although the first association with almond milk might be the modern plant-based lifestyle trend, it is dated even back to the Middle Ages when it was used as an alternative to cow milk during Catholic fasting. Once harvested, almonds undergo a series of treatments in almond milk manufacturing equipment, such as bleaching, peeling, and grinding, to get the delicious final product for breakfast and desserts.

Almond milk

Creamier, sweeter and versatile are the key adjectives when talking about cashew milk, especially compared to other plant-based milk. Additionally, it is rich in vitamins B and D, as well as essential minerals. Being a blend of cashew kernels and water, the cashew nut milk processing equipment includes a peeling and washing machine, a colloid mill, and a blending tank.

Cashew milk

Made from roasted sesame seeds this plant-based spread has a versatile repertoire in many culinary applications, most commonly used in Middle Eastern cuisine. After the roasted seeds are cooled they must be grinded and milled to create a smooth paste. In many cases, you might need to homogenize the mixture to make sure the fats are fully incorporated into the nut spread. Add it to your sauces like hummus or salad dressings.

Tahini

Scaled to meet capacity, process and regulatory requirements

Designed for efficient, continuous 24/7 operation

Suitable for micro and nano emulsions and dispersions

Modular design for reduced maintenance costs

Colour touchscreen operation with real-time schematics and performance data

Metal

Mineral

We carry dozens of metals around every day. The ubiquitous smartphone is built with no less than 20 metals, each with specific behaviors and purposes. Metals are a pervasive class of materials that have defined entire eras of human development. It is no exaggeration to say that metal processing equipment is the core of our metallic world. But, paradoxically, this manufacturing technology itself is mainly made of metal.

The nearly 5,000 known minerals on earth share some characteristics to be classified as minerals – they are inorganic, solid, naturally occurring elements and have a particular chemical formula and an ordered internal geometric structure. However, minerals are not all the same. One way to divide them is based on their physical characteristics such as hardness, luster, color, and shape. For example, the diamonds we use to make jewelry are very hard minerals while talc is a soft mineral; gold is a shiny mineral while others are less so.

Minerals

For any industrial pharmaceutical process that relies on high pressure homogenization it’s vital that the equipment used is robust enough to cope with the

High pressure industrial homogenizer - Making.com

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Guaranteed scale-up from R&D to manufacturing

  Numerous pre- and post-processing options and accessories

Modular construction for reduced ongoing costs

Full user control over pressure

  Capable of continuous operations for use in small-scale production

Biotech and pharmaceutical development programs often require a mixing method that achieves both particle size reduction and complete cell lysis. When

High pressure pilot homogenizer - Making.com

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Flexible enough to use in the lab through to small-scale production

Fully customisable for process duration, pressure, flow and force

Simple to clean and maintain, no disassembly

100% scale-up guarantee

Can it be said that we live in the Plastic age? Basically, yes. From pillows over toothbrushes, and packaging to utensils, plastic is a widely used material in our day-to-day lives. But what is it? Plastics are synthetic or semi-synthetic materials built of polymers that are easily shaped into various structures with the help of plastic processing equipment such as extruders and molders.

Plastics

Offering lab-scale to small pharmaceutical production scale output for in one unit means maximum cost-benefit when acquiring a homogenizer. Capable of

High pressure air powered laboratory homogenizer - Making.com

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Toast spread, oatmeal topping or salad dressing - nut butter can be used in various ways. Although in a culinary sense classified as such, peanuts, almonds, cashews and pecans, the popular choices for nut butter are, botanically speaking, not nuts. They are processed in a series of nut butter processing equipment to get the creamy, rich product ready for consumption.

Nut butter

Designed for the lab, with minimum sample size only 5ml

  Simple to clean and maintain

It’s vital that small units for experimentation can scale up with 100% accuracy. Ease of use, reliability and simple maintenance means increased work

High pressure electric laboratory homogenizer - Making.com

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Some of the vaccines in use today were originally developed decades ago. But advances in research, expertise and vaccine development equipment provide immunizations from bacterial and viral diseases (antibodies and cell therapy) to more people every year. The Covid 19 pandemic highlights the urgent need to scale up the production of vaccines and ensure an automated as well as reproducible manufacturing environment.

Vaccines

Insulin is a hormone that controls blood glucose levels produced by the beta cells in the pancreas. As a medication, insulin was discovered by Frederick Banting and Charles Best in 1921, for which Banting was awarded a Nobel Prize in 1923. The insulin production process involves manipulating the biological precursor to insulin and cultivating it inside bacteria using specialized technology.

Insulin

Great industrial capability with a high tolerance for errors

Straight forward design reducing the learning curve

Easier and improved handling due to the integrated valved packing port

Chromatography systems

A beverage is any kind of liquid or drink, usually other than water, made for human consumption. Beverages are further classified into two categories: alcoholic beverages and non-alcoholic beverages. Alcoholic beverages refer to liquids that contain 1% to 75% of liquor and are produced by fermentation such as wine, beer, or distillation such as vodka, rum, tequila. Non-alcoholic beverages are drinks that don’t have any liquor such as tea, coffee, fruit juices, soft drinks, and carbonated beverages. They can be produced premix or postmix, depending on the setup of your production line.

Beverages

Liquid

Batch

In the food industry, as an example, during lab-testing and studies, chromatography columns are used to detect and quantify spoilage indicators such as

Lab-scale radial chromatography columns for virus validation - Making.com

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<h2>Equipment for making dairy products - How milk is processed</h2>
Dairy processing equipment covers multiple automated sub-processes to ensure the milk products quality is at its highest. Since milk is the main ingredient of dairy products, the standard process first requires a <a href="https://making.com/technologies/pasteurizing">pasteurization process</a>. A pasteurizer unit helps to remove harmful bacteria from the milk and extend its shelf life through heating using heat exchangers. From then on, pasteurized milk undergoes different processes depending on the desired output. Usually, the milk goes through a homogenizer after pasteurizing. This improves the milk’s texture before it goes to a fermentation vat where the good bacteria (also known as “starter culture”) is added. When the fermented milk reaches a desired level of acidity, it is cooled down to end the fermentation process.

<h2>Regulations relating to dairy products</h2>
Standards to produce dairy products vary according to countries and regions. For products such as <a href="https://making.com/yoghurt">yogurt</a>, there are classifications based on the content of milk fat or protein. For <a href="https://making.com/products/cheese">cheese</a>, there are standards about how much moisture or milk fat it must contain, or in case it is made from unpasteurized milk, there is a required aging time. Processes also have regulations. For example in the United States, during the pasteurization process, every particle of milk must be heated to 143 °F (61.7 °C) for 30 minutes (holding method) or to 160 °F (71.1 °C) for 15 seconds (flash method).

Nowadays, plant-based dairy products are booming in the market - in fact, <a href="https://making.com/products/plant-based-milk">plant-based milk</a> is a product that even non-vegans can't do without. This is why people have more and more interest in adding more greens to their diet, having a healthier lifestyle, or a lactose-free diet - in fact, lactose intolerance affects 5-17% of Europeans and about 44% of North Americans. However, since not everyone is totally ready to give up the original flavors of milk, many companies are turning to hybrid dairy products that can offer both of the best worlds. Hybrids are a combination of plant-based proteins and traditional dairy products – for instance, <a href="https://making.com/almond-milk">almond milk</a> and cow's milk. With hybrids, people can still enjoy the original flavor of milk with less sugar, lower fats, fewer calories, and high sources of dietary fiber.

Hybrids as an alternative dairy product

<a href="https://making.com/technologies/aseptic-filling-equipment">Aseptic filling</a> is a necessary process in the dairy industry that requires a sterile environment for operation. Because of it, equipment, containers, and packaging material are sterilized using steam, heat, and other treatments. This ensures that the product is free from contaminants and safe for consumption. Furthermore, the processing equipment needs to be stainless steel and should incorporate some sort of CIP cleaning system. CIP stands for "Clean In Place" which essentially means that the cleaning systems has been integrated into the machinery or equipment. The reason for this is to save time due to manufacturers not having to dismantle the machinery in order to clean them.

Aseptic filling as a production requirement for dairy products

One of the most common yet important processes in the production of dairy foods and products is <a href="https://making.com/technologies/sterilization">sterilization</a>. This food processing step ensures a clean final product and helps achieve a long shelf life. The products are heated for a certain amount of time and then cooled in preparation for packing. An autoclave is used as equipment to perform such tasks.

In conclusion, specialized dairy equipment is necessary to process milk and create products such as cheese, butter, and yogurt. The pasteurization, homogenization, and fermentation processes require specific equipment. and adhere to different regulations based on country and region. Aseptic filling and sterilization play a crucial role in making safe and clean dairy products with a longer shelf life. Moreover, hybrids of plant-based proteins and traditional dairy products are becoming more popular among consumers. Whether it's for a dairy farm or cheese making, it's important to use the right equipment to produce high-quality dairy products that meet regulatory requirements.

Equipment For Bioprocessing Dairy Products Equipment

Which equipment for bioprocessing dairy products technology do you need?

Pilot high pressure homogenizer

High pressure industrial homogenizer

High pressure pilot homogenizer

High pressure air powered laboratory homogenizer

High pressure electric laboratory homogenizer

Lab-scale radial chromatography columns for virus validation

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