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Maker - Product Challenge

Products

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Changemakers

<span style="font-weight: 400">At last, you reached the final stage of processing your product - welcome to the packing world! Packing preserves and protects a product from damage, spoilage, and contamination while it makes its way from the production line to the consumer or further production. Depending on which industry your products belong to, the type of primary packaging equipment can change drastically. You need to pay careful attention to products with </span><span style="font-weight: 400">chemicals or hazardous substances since they can be potentially dangerous to human health. </span>

Packing

The word parenteral comes from Greek and means outside the intestine (para=outside and enteron=intestine). In fact, when it comes to parenterals, we are referring to those dosage forms that are administered directly into the bloodstream using a hypodermic needle, avoiding going through the gastrointestinal tract. Using parenteral filling equipment, parenteral solutions are placed in containers such as vials, syringes, or ampoules.

Parenterals

Fill liquid pharmaceutical, nutraceutical and cosmetic products in ampoules and bottles with volumes ranging from 2 to 500ml and with maximum speed of 12,000 units per hour.


<h2>Fill liquid products in ampoules and bottles with fast product change-over</h2>
The new and innovative Romaco Macofar LF 200 series are an efficient solution for the filling of liquids and are perfectly adjusted to the increasing market requirements. The systems working in the medium and high speed range are suitable for products with different flow properties. All models are very easy to operate and individually configurable. The high degree of automation optimizes the process safety and the overall equipment effectiveness.

It has a weight of 1900 to 3800kg and speed of 4500 to 12,000 units per hour depending on the machine configuration.

High-speed small volume liquid filler

Filling ampoules or vials with parenteral fluids are an essential matter for which you need to consider the highest levels of safety and reliability in the process.


<h2>Customisable Ampoule filling machine with the highest filling accuracy</h2>
Rota’s filling machines allow the filling from small scale batches to mass production with optimal performance range. Filling can be done for the ampoules and vials that are from 0.2 ml to 30 ml and can afford up to 24.000 per hour.

Ampoules are the perfect containers to store parenteral fluids and their filling demands rigidly controlled sterile conditions. Rota’s own rotary pumps guarantee high filling accuracy in continuous operation without re-adjustment. This Ampoule filling machine comes with an easy to handle approach when looking to clean and sterilise the filling system, whether manually or with automatic CIP/SIP systems.

Ampoule filling machine

Any pre-filled syringe can be filled and closed with this fast and easy machine that helps in manual handling as well as for fully automated conveying of the tubs.


<h2>A processing machine for nested and pre-sterilized syringes</h2>
Rota has decades of experience as a supplier for the pharmaceutical industry. This processing machine for nested and per-sterilized syringes is a translation and integration of Rota’s experience for meeting the customer needs.

They main feature is the use of latest servo motor technology. Serial kinematics robotics (SCARA) and advanced control programming allow the precise execution of each individual processing step. It is provided with automated systems for de-bagging, lid and fleece inlay removal. The machine capacity covers a range of up to 22.000 syringes per hour.

Filling and closing machine for parenterals

Labels for ampoules, vials and bottles are typically applied at the end of the packaging process. What control and printing features do you want to excel within your particular work environment?


<h2>Tailor made labeling solutions for ampoules, vials and bottles</h2>
The labeling machines of Rota meet all requirements of the pharmaceutical industry in an optimal manner. You need properly attached and error-free labels to market your drugs. Rota machines are ideal for integration of any kind of control and printing features from various manufacturers, with top precision at high speeds.

Flexible solutions at in-feed and out-feed of the labeller allow its integration into packaging lines from other manufacturers, as well. Upright transport of all containers, whether of glass or plastic, guarantees a high precision application of labels. Rota labeling machines for ampoules, vials and bottles can label up to 24.000 containers per hour.

Labeling machines for pharmaceutical bottles

For smaller-scale production of vials and syringes for the injectables market, sterile conditions and accurate metering are still required for filling, stopping and crimping a wide range of container sizes.
<h2>Fill vials and syringes in basic, yet flexible, configuration</h2>
The i-Dositecno MI-I is specially designed for sterile pharma filling, able to fill sterile liquid and powder in doses from 1 to 500 mls into vials and syringes.

3,000 units per hour can be produced for formats up to 80 mm diameter in simple configuration, while 6,000 units per hour can be attained for smaller units up to 26 mm diameter in a double configuration.

Filling is achieved by means of peristaltic, stainless steel rotary, ceramic rotary or CIP/SIP rotary pump. Stoppers are introduced by servo-driven pick and place, however, capsule introduction and crimping heads are controlled by pneumatics.

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Start-up sterile filling line for injectables

<span style="font-weight: 400;">Automatic cartoning for cosmetic or pharmaceutical products is a requirement for all but the lowest volumes of production. Modern machines that can operate either standalone or as part of bespoke line offer the maximum flexibility to manufacturers. High accuracy and reliability are key to ensuring this vital part of the packing process allows your line to operate at maximum efficiency.</span>
<h2>Flexible cartoner for pharmaceutical and cosmetic products</h2>
<span style="font-weight: 400;">The A1 Cartoner from FamarTec is an alternate motion cartoning machine for the horizontal packaging of pharmaceutical products and cosmetics inside pre-glued cartons. The A1 can be operated as a standalone machine, or it can be coupled to a packaging machine such as a blister packer, tray loader, tube-filler, etc. It has an optimum capacity of 100 cartons per minute.</span>

<span style="font-weight: 400;">Designed to GMP standards, the A1’s balcony construction allows complete access to all parts of the machine, simplifying routine maintenance and service, as well as carton changeover. Brushless motors are used throughout for increased reliability, longevity and efficiency.</span>

<span style="font-weight: 400;">A range of closure methods can be accommodated, including slot, glue or combined glue and slot flap closure, and the machines are set up for the assembly of dedicated feed units for the product to be packed.</span>

<span style="font-weight: 400;">The compact layout and quick changeover makes the A1 ideal for almost all lines and production areas. The addition of a touchscreen control panel with icon control makes it simple and easy to operate and monitor.</span>

<span style="font-weight: 400;">A large range of optional units enables you to tailor A1 to your exact requirements. Options include automated instruction leaflet insertion, barcode reading, OCR/OCV systems for pre-printed codes and data, inspection systems to confirm the presence of instruction inserts and product within cartons, stamping, inkjet or laser coding systems, tamper-evident systems for glue or label tampering, and full integration with serialisation systems.</span>

Horizontal cartoner for pharmaceutical applications

Aluminum blisters are mainly used for packaging products that are sensitive to light, moisture or a combination of both, i.e. where a complete tightness is required


<h2>Fast cold form blister packaging for small batches</h2>
The Alu250 by Tommy Nielsen is designed to work for R&amp;D and smaller pharmaceutical batches or in laboratories. During blister production, pieces of foil - possibly already cut to the required shape - are placed on the blister-forming tool. The machine is then activated and the blister formed. Afterwards, the Alu-blisters can be sealed using a separate sealing machine - Universal S, FS or FSX.

The machine can make up to 1200 items per hour, depending on the blisters design.

Cold forming aluminum blister machine for capsules

Controlling contamination is on every manufacturer's mind when packaging items, such as syringes. When medical items are produced, packaging needs to have protective factors to exclude contamination of pharmaceutical products.
<h2>Flexible forming with vacuum for blister packaging</h2>
The Uniline by Tommy Nielsen is a fully automatic blister packing machine that both forms and seals. The machine forms blisters from roll stock. Forming can either be done positively with vacuum, negative with vacuum and compressed air or vacuum with plug assist. After the forming process, blisters are automatically cut and placed in sealed trays. Pre-printed and pre-cut cards are loaded into magazines from where these cards are automatically placed on top of the filled blister and sealed. The heating of the foil (PVC, PET, or PS) is obtained using thermostatic control.

The machine uses the whole width of the foil, which eliminates waste. The standard length of the lading section is 1500 mm. The maximum forming and sealing area is 200 x 400 mm or 200 x 600. The machine offers a variety of forming programs, and the blister length can be easily varied.

Automatic forming and sealing blister machine for packing syringes

Find production technology for Parenterals packing, and connect directly with leading machine manufacturers worldwide

Parenterals packing

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