Mixes and Granulates Powders for Tablet Production

The FabLife High Shear Mixer Granulator from Fabtech is engineered to tackle the rigorous demands of pharmaceutical and biotech processing. Its ergonomic design integrates a robust four-blade impeller and rapid chopper blades to ensure superior dry and wet granulation. Ideal for producing tablets, capsules, and granules, this machine delivers homogeneous mixing through precise binder distribution and controlled granule size growth. Available in lab, pilot, and commercial models, it suits various operational scales while maintaining adherence to GMP and 21 CFR Part 11 standards for regulatory compliance.

Built primarily from SS 316 for enhanced corrosion resistance, each unit features a PLC-controlled operation with customizable recipe settings, ensuring streamlined integration into your production line with pneumatic lids and discharge ports. The inclusion of a binder sprinkle nozzle and vent filter further enhances its efficiency, while the wet co-mill at discharge guarantees consistent drying. Focused on reducing energy use, this mixer is designed to help you maintain high efficiency and product quality. For ease of maintenance, the mixer allows quick access for cleaning, with an emphasis on minimizing downtime and ensuring a contamination-free environment.

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Mixes and Granulates Small Batch Products

The P100 High-Shear Mixer Granulator from DIOSNA is an essential solution for industries like food, pharma solids, cosmetics, feed, and fine chemicals, where precise mixing and granulating are crucial. This compact unit excels in producing even mixtures and granulates across smaller batch processes, covering 30% to 90% of its total 120-liter volume. The mixer is designed with highly efficient mixing tools and a vessel geometry that promotes optimal product flow. It integrates seamlessly into various production settings, whether placed freely or against a technical zone wall, complying with ATEX requirements for safe operations under inert conditions. Known for its energy-efficient operation, the P100 is pressure shock resistant and includes features for easy cleaning, such as a swing-open spout housing. Ideal for producing granulated sugar, pharmaceutical tablets, face cream bases, and more, it adapts reliably to your production demands with flexible installation options and sturdy design.

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Mixes and Granulates Pharmaceutical Solids

The P 250-1250 from DIOSNA is a production-scale mixer granulator designed to master the challenges of pharmaceutical and chemical manufacturing. This piece of equipment excels in efficiently mixing and granulating pharmaceutical solids, combining robust high-shear technology with versatile application capability. It supports a variety of end-products, from tablet formulations and starter cultures to specialty chemical blends.

Working through a closed system, the DIOSNA mixer granulator optimizes the processes of mixing and granulation, ensuring consistent, high-quality outputs with each batch. The integrated DIOSNA-Toollift allows seamless inspection of shaft seals, simplifying maintenance and reducing downtime.

Engineered for seamless integration, it operates with advanced automation, including an integrated industrial PC that ensures data integrity and compliance with 21 CFR Part 11 standards. Easily adaptable, this equipment offers automated cleaning features and effective remote service capabilities for streamlined operations and reduced labor costs.

Crafted from corrosion-resistant materials, it meets global GMP standards, providing long-lasting reliability in demanding production environments. Whether you are in pharmaceuticals, food, cosmetics, feed, or fine chemicals, the P 250-1250 ensures your production line remains efficient and consistent.

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Mixes, Granulates, and Dries in One Unit

The P/VAC 10-60 from DIOSNA is a versatile single-pot processor that excels in mixing, granulating, and drying operations within one compact unit. Its design allows for efficient processing of pharmaceutical tablets, cosmetics, foods, feed, and fine chemicals. It features an integrated peristaltic pump for precise liquid addition, ensuring batch consistency. The P/VAC 10-60 can be easily integrated into automated pilot and batch operations thanks to its PC control system with batch data logging and 21 CFR Part 11 compliance. Constructed with replaceable containers and seals, it offers durability in diverse production environments. This equipment supports energy-efficient operations by maintaining optimal motor speeds, and it includes CIP-capable features to simplify maintenance and reduce downtime. Suitable for R&D and processing departments, it meets stringent quality standards applicable to its industries.

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Mixes and Granulates Solid and Liquid Mixtures

The V10 – V100 from DIOSNA is a versatile universal mixer granulator designed for industries such as food, pharmaceuticals, chemicals, plastics, and cosmetics. What sets this equipment apart is its ability to combine mixing and granulating through spray technologies, ensuring uniform and reproducible particle sizes. The equipment accommodates a range of applications, including spice blends, pharmaceutical tablets, and cosmetic pigments. With a compact cylindrical-conical design, it offers easy operation through push-button controls and timers. This robust mixer handles batch, manual, pilot, and entry-level operations, supporting both solid and liquid product types. Available from 11.5 to 180 liters, the machine aligns with your production needs, ensuring efficient integration into existing processing lines. Built for durability, it supports a wide array of end-products like polymer additives and herbal extracts while optimizing energy usage through its powerful, adjustable chopper.

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Mixes and Granulates Industrial Scale Batches

The V250 – V1600 Universal Mixer Granulator from DIOSNA Dierks & Söhne GmbH offers robust and versatile mixing capabilities for industrial manufacturing. This equipment’s vertical design incorporates a cylindrical container with a conical top, a three-bladed bottom mixing tool, and a side-mounted chopper. It is ideal for blending food, pharmaceutical, cosmetic, and chemical materials, including bakery doughs and pharmaceutical granules. The V250 – V1600 accommodates volumes from 210 to 1,400 liters, supporting large-scale production with swift processing times. It features easy-to-use push-button controls and a compact, low-profile construction for seamless integration into existing production lines. Equipped with low-wear air gap seals and a large emptying valve, it ensures efficient operation and maintenance. Available in materials suitable for various industrial applications, the mixer granulates efficiently while meeting industrial compliance and offering customization and engineering support.

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Maximizes Mixing, Granulation, and Drying Efficiency

The CGS Granulation Line from DIOSNA Dierks & Söhne GmbH is engineered for pharmaceutical, food, and cosmetics industries to efficiently combine mixing, granulation, and drying processes. Geometrically optimized for seamless transition between mixer and dryer, this system minimizes product-contacting surfaces, enhancing product yield and reducing cleaning challenges. Its batch processing capability ranges from 25 to 600 kg, supported by an explosion protection feature compliant with ATEX standards, ensuring safety during solvent operations. The system’s flexibility includes integration with 21 CFR Part 11-compliant software for precise batch monitoring. Designed for ease of maintenance, the CGS Granulation Line features accessible components and supports PAT concepts to meet GAMP 5 standards.

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Granulates and Mixes Pharmaceutical Compounds

The containment mixer granulator from DIOSNA seamlessly integrates into pharmaceutical and fine chemical production lines, offering a tailored solution for precise granulation and mixing. Its innovative containment system ensures operator safety and product integrity by operating under hermetically sealed, negative pressure isolators. This equipment excels in producing pharmaceutical tablets and granules, cosmetic creams, and fine chemical compounds by facilitating essential processes such as mixing, granulation, and sampling with minimal exposure to contaminants. Designed for research, development, and pilot operations, it supports batch processing with flexibility in switching operations or conducting product testing mid-process. Compliance with OEB5 standards ensures high safety levels, while the inclusion of special transfer systems streamlines the charging and discharging of materials. Additionally, its construction allows for easy integration with existing systems, using a PLC-controlled interface for enhanced automation. Available customization options include additional scales, pumps, and mills to suit diverse production needs, all while maintaining efficient decontamination and minimal maintenance requirements.

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Mixes, Granulates, and Dries in One System

The VAC 150-1200 from DIOSNA is a robust single-pot processor engineered to streamline the mixing, granulation, and drying stages of production for pharmaceutical solids, cosmetics, and fine chemicals. Its dual-zone heating with a cylindrical mixing bowl and an efficient wall scraper ensures quick drying, even for adhesive products. The system operates under vacuum, with optional stripping gas distribution to augment drying efficiency. Suitable for production-scale operations, it accommodates diverse applications, including pharmaceutical tablets and cosmetic creams. The unit integrates seamlessly with an industrial PC, facilitating full automation and remote maintenance. It ensures compliance with 21 CFR Part 11 for quality assurance, while the CIP/WIP process allows effortless cleaning. Stainless steel construction provides durability and chemical compatibility, with customization options available for specific processing requirements.

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Granulates, Dries, and Coats Pharma, Cosmetics, and Chemicals

The Minilab RC from DIOSNA Dierks & Söhne GmbH is a versatile benchtop unit designed for R&D environments in pharmaceuticals, cosmetics, and fine chemicals. Its unique Rapid Change system allows seamless transitions between fluid-bed processing and drum coating, enabling efficient granulating, drying, and coating workflows. The unit features a transparent design for easy process monitoring and full control via an integrated graphic display. Applications include producing granules, face powder, and enteric-coated tablets. With bowl sizes ranging from 1 to 7 liters and batch capacities tailored for precise formulation, this equipment offers flexible operation for small-scale production trials. It boasts tool-free disassembly for easy cleaning and maintains a compact footprint for lab settings. The Minilab RC operates under strict compliance with GMP standards, ensuring quality and safety in your research processes.

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