Filters, Dries, and Processes Slurry for Pharmaceuticals

The SimpleFilter™ from Powder Systems Limited is an engineered solution for small scale and pilot batch processing in pharmaceutical, chemical, and biotech industries. This Nutsche filter dryer stands out with its compact, mobile design allowing for efficient filtration, drying, and washing of slurries, cakes, and solids. Its single plate pressure and vacuum vessel integrates a glove-bag containment system, ensuring safe discharge and sampling under a nitrogen purge. Available in 316L stainless steel or PFA-coated options, it offers significant corrosion resistance. The system is designed for GMP compliance, supporting applications such as API purification, specialty chemicals, and biopharmaceuticals. With vessel volumes ranging from 50 to 130 liters and configurable with agitation and CIP systems, SimpleFilter™ enhances adaptability and production agility, ensuring high product recovery and maintaining crucial process parameters consistent from R&D to commercial production stages.

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Enables Aseptic Sampling and Sterilization

The PE series of sampling devices from Equans – Pierre Guerin are engineered specifically for the rigorous demands of the food, beverage, and biopharmaceutical sectors. These devices are crafted from durable Stainless Steel EN 1.4404 (316 L) and are designed to be wall-mounted, ensuring seamless integration into your production line while maintaining aseptic conditions. Choose from four models—diaphragm, needle valve, manual sterilisable-in-place valve, or pneumatic sterilisable-in-place valve—to meet the specific needs of your operation. Ideal for sampling in applications requiring stringent quality and microbiological control, these devices support a variety of liquid end-products, including infant formula, vaccines, and energy drinks. Their robust construction ensures minimal maintenance while the clean-in-place and sterilisable-in-place features enhance operational efficiency. Suitable for environments upholding high standards of hygiene, these devices comply with industry certifications, delivering reliability and precision in your processing and sampling tasks.

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Fills and Caps Vials and Syringes Aseptically

The ISOL-AIR Series from the Marchesini Group provides a state-of-the-art solution for aseptic filling and containment tailored for pharmaceutical manufacturers and biotech companies. These containment cabinets, configurable as Closed RABS or Isolators, excel in filling and capping vials and syringes. Designed to support aseptic processes, they integrate seamlessly into your production line, optimizing filling capacities while ensuring operator and product protection. They cater to the production of vaccines, insulin, oncology drugs, and more, addressing complex sterile injectable requirements. The series features aseptic transfer connections through Rapid Transfer Ports (RTP) and is fully automated with a programmable Wash in Place (WIP) system, including manual spray guns for flexible cleaning options. The equipment supports bio-decontamination cycles by Vaporized Hydrogen Peroxide (VHP) and incorporates Environmental Monitoring Systems (EMS) for maintaining optimal processing conditions. Energy efficiency and product safety are prioritized with dedicated HVAC Air Handling Units (AHU) and Bag-IN/Bag-OUT filters for processing potent drugs. Marchesini Group’s commitment to quality ensures that these machines meet stringent pharmaceutical compliance standards, offering customizable configurations to suit your unique operational needs.

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Dedusts and Conveys Tablets and Capsules

The KD70A Series from Krämer AG is designed for efficient dedusting and conveying of tablets and capsules in the pharmaceutical, nutraceutical, and vitamin industries. This vertical vibratory deduster integrates seamlessly into your production line, using a gentle vibratory mechanism to remove excess dust while maintaining product integrity. Suitable for a wide range of tablet sizes, from standard aspirin and vitamin C tablets to micro-tablets, the KD70A Series ensures compliance with industry standards, including GMP and SMEPAC certification, and meets ATEX guidelines for dust containment. Its continuous operation capability, paired with an automatic control system, enhances throughput while minimizing manual intervention. Constructed from high-grade stainless steel, this equipment offers excellent corrosion resistance, ensuring longevity and reliability. The system supports quick cleaning protocols and easy maintenance to minimize downtime. Flexible integration options and engineering support allow customization to match specific production requirements, making it an indispensable addition to your facility.

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Recovers and Cleans Pipelines Efficiently

The SteriPig Product Recovery System from INOXPA is designed to revolutionize the recovery and cleaning processes in your pipeline operations. By employing a hygienic PIG—and propelled by compressed air—the system ensures maximum retrieval of residual high-value products, such as pharmaceutical gels and cosmetic creams, minimizing waste and optimizing pipeline cleanliness.

This system is especially beneficial for viscous media, effectively recovering and preparing pipelines for CIP without introducing contaminants. Its ability to handle complex media like ointments and emulsions is notable, positioning it as indispensable for pharmaceutical, cosmetic, and even food and beverage industries.

With connections ranging from 1 ½” to 3″ and a hygienic design in accordance with EHEDG specifications, SteriPig offers wide adaptability for various pipeline requirements. Featuring automatic butterfly valves and a control panel for automation, it seamlessly integrates into existing production lines, ensuring continuous, high-speed operations while promoting efficient use of resources.

Constructed from durable materials like AISI 316L and AISI 304 stainless steel, the SteriPig system is available in a range of materials to suit diverse process needs, including options with EPDM and Viton spheres. It adheres to stringent FDA standards, ensuring complete safety and efficiency in sensitive applications.

Furthermore, the system supports customization with various connection types and gasket materials, providing tailored solutions to meet specific operational demands. Designed for minimal maintenance through integrated CIP capabilities, the SteriPig system reduces downtime and enhances the productivity of your production environment.

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Compresses and Contains High-Risk Pharmaceutical Tablets

The PREXIMA THC from IMA Group is a high-containment tablet press designed for pharmaceutical manufacturers dealing with potent or hazardous compounds. Specially engineered to compress tablets while ensuring operator safety, it features sealed doors, negative pressure zones, and glove ports for secure handling during operations. Its standout configuration flexibility, with a unique 8-station turret, supports both B and D tooling types, catering to a wide range of tablet sizes. The machine is ideal for producing paracetamol, ibuprofen, and anti-cancer drugs, among others. With a maximum output of 96,900 tablets per hour, the PREXIMA THC ensures efficient throughput. Equipped with the MAX corporate HMI, it enhances operator efficiency and process predictability. The machine’s robust construction ensures compliance with GMP standards and facilitates easy cleaning and maintenance with built-in cleaning ports. Its design supports integration into existing production lines, accommodating R&D, pilot, and high-speed production workflows.

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Automates Aseptic Filling and Stoppering Operations

The INJECTA 36 from IMA Life is an advanced robotic system specially crafted to enhance aseptic fill-finish capabilities for pharmaceutical manufacturers and biotech companies. With a capacity to process up to 36,000 units per hour, it offers unparalleled speed and precision for handling pre-filled syringes, vials, and cartridges. The system employs robotics to fully automate filling, stoppering, and inspection processes, minimizing human intervention and reducing contamination risk. Its compatibility with isolation technology ensures flexibility in multi-product environments, while automatic in-process control guarantees accurate fill integrity. The INJECTA 36 seamlessly integrates into existing production lines, offering downstream connections for de-nesting and inspection tasks. Built to meet rigorous GMP standards, it is engineered for longevity and low maintenance with features like automatic weight cell calibration and a reduced isolator shell width for efficient space utilization.

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Ensures Aseptic Filling and Cross-Contamination Control

Developed by IMA Life, the ISOLATION TECHNOLOGY system is integral to aseptic fill-finish lines, particularly for pharmaceutical and biotech sectors. It minimizes human intervention with automated filling systems, ensuring sterility and containment for liquid and powder products like injectable vaccines and cytotoxic drugs. Leveraging cross-contamination control expertise, it integrates seamlessly into high-speed, continuous operations. Its robust design offers dedicated HVAC systems and customizable VPHP cycles, compatible with various isolators, vial washers, and alu-capping machines. The system’s energy-efficient components and remote monitoring capabilities enhance its operational efficiency, while its superior material options meet stringent GMP compliance standards. This system simplifies cleaning through integrated spray nozzles and CIP modes, supporting flexible configurations to suit specific processing needs.

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Opens and Prepares Sterile Packages

The BAG OPENING AND TUB/TRAY OPENING system from IMA Life is designed for aseptic processing facilities looking for a fully automated solution to handle sterile packaging. It uses robotic technology to efficiently open and de-lid double-bagged packages, ensuring minimal risk of cross-contamination during processing. Commonly utilized in the pharmaceutical and biotech industries, this system processes sterile vials, lyophilized drugs, and other injectable forms with precision.

Operating with continuous automation, the system integrates seamlessly within high-speed production lines. It features restricted barrier systems (RABS) and complies with Annex 1 regulations, confining operations and preserving sterility through every phase. Components like the robotic cutting arm and de-lidding station are engineered for durability and precision, and the entire unit is adaptable to various container configurations. Maintenance is streamlined with an emphasis on reducing operational downtime, making the system integral for modern sterile packaging environments.

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Controls and Isolates Hazardous Material Processing

The containment and isolation systems from Hosokawa Micron Ltd. are designed for sectors where safety and environmental protection are paramount. Known for their robust design and integration capabilities, these systems control and isolate hazardous materials during processing, ensuring optimal safety and compliance. They feature gloveboxes and downflow booths that support industries such as pharmaceuticals, chemicals, and nuclear fuel processing, making them essential for handling APIs, catalysts, and battery materials.

With precise filling and weighing systems, these solutions accommodate continuous, pilot, and manual operations, integrating seamlessly with existing production lines. Their automation capabilities allow for efficient process control and remote monitoring, enhancing operational efficiency and safeguarding personnel. Constructed from corrosion-resistant materials, these systems maintain integrity in challenging environments and are compliant with GMP standards for pharmaceuticals.

Additionally, the systems support efficient cleaning through CIP/SIP technologies, streamlining maintenance and reducing downtime. Hosokawa Micron provides comprehensive engineering support and customization options, ensuring tailored solutions for complex processing challenges.

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