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Labels provide customers with important information about both your product and your brand. Different labeling technology attaches the printed film to the packaging using a range of methods such as shrink wrapping, side sealing, and adhesives. For added traceability and protection, you may also use serialization coding equipment and anti-tampering labeling systems.

Labeling

<em>“How clean does my equipment needs to be?” </em>That's what manufacturers often wonder about in order to meet the high sterilization standards the pharmaceutical industry demands. Lending manufacturers helping hand have been single-use bags, also known as disposable, first introduced in the late 1990s. They immediately gained popularity because they reduce the risk of cross-contamination, minimalize cleaning and sterilization demands, and require a low capital cost.

Single-use bags

<span style="font-weight: 400;">In the pharmaceutical industry, product serialization is the cornerstone of all legislative requirements for traceability. An automated inline coding and labeling system provides the easiest and most reliable way of addressing serialization needs without adversely impacting on line performance.</span>
<h2>Folding-box serialization units for high flexibility/high speed</h2>
<span style="font-weight: 400;">The Amacoder range from Hicof are industry-leading serialization solutions for the pharmaceutical industry, available in two specifications:</span>

<span style="font-weight: 400;">Amacoder FLEX - offers the maximum flexibility for packaging sizes. The maximum box depth is 300 mm and the maximum throughput is 75 boxes per minute (depending on box size). This is ideal for batch production and lines with frequent size changeover.</span>

<span style="font-weight: 400;">Amacoder SPEED - offers the highest speed at up to 150 boxes per minute for a maximum box depth capped at 200mm. This is perfect for dedicated smaller box lines where maximum throughput is desirable.</span>

<span style="font-weight: 400;">The Hicof Amacoder machines are supplied as standard with one inkjet printing unit and one cartridge and one camera on the operator side. Additional printing heads are available as an option. Two labelers enable the application of tamper-evident seals on both sides of the folding box. All box flap configurations are supported, making the Amacoder suitable for use with any existing line.</span>

<span style="font-weight: 400;">The Amacoder line has been designed to reduce moving parts and complexity as far as possible, offering an attractive price point as well as reducing the footprint to a minimum. The slower movement of boxes through the Amacoder means a very low rejection rate, offering further cost savings.</span>

<span style="font-weight: 400;">The code-reading camera is fully ISO/IEC 15415 compliant, and the complete coding and labeling line offers a comprehensive corporate, easy to operate, GxP compliant database to an integrated solution. The Amacoder IT system allows the processing of all serialization data, supports related business processes and offers optional interfaces to business and governmental partners.</span>

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Serialization coding and labeling equipment

The pharmaceutical sector is unquestionably one of the major industries that rely on the Blow-Fill-Seal process. Blow-Fill-Seal containers are used to store rinse solutions, eye drops, antiseptics, and infusion solutions. Quality inspections are usually required for this process to ensure that the product’s quality is uncompromised. However, when it comes to packaging delicate materials such as medicines, finding a labeling machine that ensures ease of use and maximum operator safety is incredibly difficult.
<h2>Ensure quality application of self-adhesive labels</h2>
Specifically designed for BFS container handling, Etima’s Pharma ML-BFS guarantees the inspection, data management, and labeling required to fulfill the needs and requirements of every client. The ML-BFS can be used for vials, boxes, and cylindrical or flat-surfaced containers. Its advanced technology ensures easy application of self-adhesive labels, while its Optical Character Recognition and Optical Character Verification technology detects and weeds out any printing errors. This technology also inspects the quality and legibility of the text and determines whether it meets the highest standards.

Featuring a diaphanous space and a curved finish, it is easy to maintain and clean, while can be adjusted quickly. This customized-machinery is designed to meet the requirements of every client and is further integrated with artificial inspection or vision, and Track &amp; Trace systems.

Labeling machine for BFS containers

It’s essential for pharmaceutical companies to provide the highest quality ampoules to customers and to maintain a high status in regards to quality provisions as well. The labeling on tubes and syringes helps healthcare workers accurately determine drug batch numbers, administration, expiry date, and other important medical information. However, accurately labeling syringes and tubes is often an extremely time-consuming process.
<h2>Apply self-adhesive labels quickly and precisely</h2>
Designed to apply self-adhesive pre-printed labels, the ETIMA PHARMA ERN is ideal for flat surfaces, oval containers, truncated cone, unstable cylindrical, and slightly conical containers. It is designed with up to 5 labeling heads and boasts an output of up to 25,000 containers/hour.

The base of the labeling machine is designed with a round footprint for quick and easy access, while its protection cabin features vertical lift doors to ensure ease of use. Lastly, the machine allows the integration of verification or inspection systems and market printing systems, further ensuring greater flexibility.

Labeling machine for ampoules

Including serialization and aggregation inspection systems to packaging lines helps manufacturers to make the distribution chain more efficient while ensuring consumer safety. Having different systems that handle serialization, aggregation and visual inspection can require different training and be time-consuming. A single system that can manage all three fuctionalities in one could be a solution to reduce effort, time, and cost.
<h2>Complete track and trace solution for serialization, aggregation and quality inspection</h2>
The Hector system from Hicof is a system with a complete track and trace system for serialization, aggregation and quality inspection. It can manage the process of serial numbering with different printing systems such as Thermo Inkjet, Continuous Inkjet or Laser printing. The Hector system has a controller that can be connected to cameras for the print inspection process. Its integrated register allows tracking processes through machines based on encoder signals. Hector system features a wide range of optical systems that helps in managing the aggregation of serialized products over multiple packaging levels. It can create individual identifiers of the aggregated container by connecting to label printing systems. Hector manages the visual quality inspection process as Pharmacode reading, filling control of Blister cavities, and quality inspection of tablets and molded products.

Serialization and aggregation inspection system

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Single-use bag labeling

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Serialization coding and labeling equipment

Labeling machine for BFS containers

Labeling machine for ampoules

Serialization and aggregation inspection system

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