Dries and Forms Precise Particles

The GSD GENESIS™ Spray Dryer from Freund delivers precision particle engineering for pharmaceutical and industrial needs. This equipment utilizes an innovative atomization process to convert liquids into uniform, dry powders swiftly and efficiently. It’s ideal for producing active pharmaceutical ingredients, excipients, and specialty chemicals. The modular design includes various nozzle options, enabling you to tailor the drying process to your specific product requirements. With an evaporation capacity ranging from 6 kg/hr to 50 kg/hr, it supports continuous, high-speed operations. The GENESIS™ boasts a touch screen control system for straightforward integration and automation within existing lines. EcoClean™ technology reduces water and chemical use, minimizing environmental impact and operational costs. Available in materials meeting CE, ATEX, UL, NFPA, and CSA standards, this system is engineered for safety and compliance in Class 1, Division 2 environments.

The post Commercial scale spray dryer for pharmaceutical materials appeared first on Making.com.

Processes and Granulates Powders into Uniform Granules

The GMXB-LAB Micro GRANUMEIST® by Freund is a lab-scale high shear wet granulator, integral to transforming powders into consistent, high-density granules for pharmaceutical, biopharmaceutical, and fine chemical applications. Its bottom-drive design ensures easy maintenance and user safety, while interchangeable product bowls provide flexibility across 1L to 6L batches. This granulator handles mixing and homogenizing processes with precision, supported by a peristaltic pump for both aqueous and solvent-based operations. The system also features user-defined speed settings and optional Smart-Safe™ containment for controlled environments. The integration of a color touchscreen control and USB data collection facilitates streamlined operations and process validations, ensuring compliance with industry standards.

The post High shear GMP wet granulator appeared first on Making.com.

Granulates and Mixes Powder into Dense Granules

The GMXB-Pilot GRANUMEIST® from Freund is a high shear wet granulation mixer designed for precise and efficient processing in the pharmaceutical, nutraceutical, and fine chemical industries. This equipment stands out due to its bottom-drive design, which facilitates easy cleaning, faster processing times, and enhanced safety. Featuring interchangeable bowls (10L, 25L, 65L) and user-defined mixer and chopper blade speeds, it supports both aqueous and solvent processes. Its integrated peristaltic pump and optional vacuum drying make it suitable for flexible batch operations. Containment is enhanced with the optional Smart-Safe™ system, while a color touchscreen offers validatable and automated process control, aligning with 21 CFR Part 11 compliance. Engineered for scalability and equipped with proportional mixer blade tip speeds, the GMXB-Pilot accommodates diverse granulation needs, from granulated vitamins to fine chemical powders. Additionally, its quick changeover design and options for jacketed and vacuum drying bowls streamline maintenance and operational efficiency.

The post Pilot High shear granulator for wet granulation appeared first on Making.com.

Facilitates Wet Granulation and Mixing

The GMX-LAB Micro GRANUMEIST® from Freund-Vector is a high shear granulator designed to deliver efficient wet granulation and homogenous mixing. Its top-drive design simplifies cleaning and maintenance, while ensuring faster processing times without compromising user safety. With a range of applications, including pharmaceuticals and nutraceuticals, it can produce immediate and extended-release tablets, as well as multivitamin and enzyme supplements.

The system features interchangeable 1L and 4L bowls, offering flexibility for varying batch sizes, and integrates user-defined settings for mixer and chopper blade speeds. Equipped with an optional jacketed bowl for product temperature control and an integrated peristaltic pump for precise solution addition, it ensures consistent granule formation. The Smart-Safe™ containment option enhances operational safety, while the proportional mixer blade tip-speeds and customizable bowl and blade geometries optimize processing outcomes.

Its color touchscreen control system simplifies operation, and the process control is designed for validation, supporting multiple end-point detection parameters. The unit supports scalability with its modular design and comes equipped with a USB data collection port for process monitoring. This portable and self-contained system is ideal for bench-top and pilot-scale operations in R&D and laboratory settings within pharmaceutical, biotech, and chemical industries.

The post High shear lab granulation system for powder processing appeared first on Making.com.

Performs Wet Granulation and Precise Mixing

The GMX-LAB Mini GRANUMEIST® from Freund-Vector is a compact high shear wet granulation system designed to streamline pharmaceutical, nutraceutical, and fine chemical production processes. This top-driven granulator facilitates efficient granule formation through targeted mixing and homogenization, essential for producing effervescent tablets, multivitamin capsules, and APIs. It integrates an interchangeable bowl system with capacities of 4L and 8L, allowing for tailored operations and scalable research outcomes. Intuitive user-defined settings, including mixer and chopper blade speeds, ensure precision, while the optional jacketed bowl provides temperature control for sensitive formulations. The GMX-LAB Mini supports both aqueous and solvent-based processing and is equipped with an integrated peristaltic pump for consistent solution addition. Enhanced with a color touchscreen control system, it offers validatable process control with multiple end-point detection parameters to adapt to varied laboratory and pilot-scale needs. Built with user safety and hygiene in mind, its quick change design requires no tools and includes Smart-Safe™ containment for contamination-free cleaning. This system complies with GMP standards, ensuring quality and traceability in your production line.

The post Mini High shear granulator for wet granulation appeared first on Making.com.

Homogenizes and Granulates Powders Efficiently

The GMX GRANUMEIST® from Freund is a high shear wet granulator and mixer designed for pharmaceutical, nutraceutical, and fine chemical applications. It features a top-drive system, simplifying cleaning and maintenance while enhancing user safety. This equipment excels in creating consistent granule density and homogeneity for products like effervescent tablets, protein powders, and APIs. With bowl capacities ranging from 150L to 1200L, it supports batch operations and integrates easily into existing production lines with user-defined mixer and chopper speeds. The system offers optional vacuum drying for one-pot processing and an EcoClean™ technology for efficient cleaning. Compatible with cGMP standards, it promotes secure operations with a Smart-Safe™ containment option and features a color touch screen for process control, supported by multiple end-point detection parameters.

The post High shear wet granulation line appeared first on Making.com.

Processes and Dries with Solvent Recovery

The GSD-800 GENESIS™ from Freund is a GMP-compliant spray dryer highly suited for biopharmaceutical and chemical industries. It features a closed-loop system with nitrogen inerting for safely processing heat-sensitive materials while recovering solvents efficiently. This system accommodates a diverse range of applications, including the production of vitamins, enzymes, and pharmaceutical tablets. With an evaporation capacity of 4 kg/hr for water-based solutions, it ensures precise control over particle size and moisture content. The GSD-800 integrates seamlessly with your production line through its user-friendly COMPU™ control system, offering minimal operator interaction and optional 21 CFR Part 11 compliance for data integrity. Its modular gas disperser and various nozzle options allow tailored adjustment to meet specific particle characteristics and drying requirements. Built from durable materials that ensure chemical resistance, the system also includes an innovative cleaning mechanism for straightforward maintenance and removal of all product contact surfaces.

The post Pilot Gmp spray dryer system for small-scale manufacturing appeared first on Making.com.

Converts Liquids into Consistent Powders

The GSD-LAB Micro GENESIS™ from Freund is a benchtop spray dryer designed specifically for pharmaceutical and chemical R&D laboratories. This equipment features a stainless-steel drying chamber, and utilizes a 2-fluid atomizing nozzle for efficient drying and granulation. It supports both aqueous and solvent processes, making it versatile for developing monoclonal antibodies and peptide hormones. With an evaporation capacity of 0.5 kg/hr, it operates in single-pass mode for rapid formulation. The system is portable and suitable for use under a hood or inside an isolator, integrating seamlessly into existing lab setups. Energy-efficient, it offers options like a HEPA filter and Smart-Safe™ containment for enhanced safety and compliance with CE, ATEX, UL, and NFPA standards.

The post Benchtop spray dryer for drug discovery appeared first on Making.com.

Compacts and Granulates Pharmaceutical Powders

The GFC GRANUFORCE™ from Freund is a versatile roller compactor specifically designed for dry granulation and densification in pharmaceutical and nutraceutical manufacturing. Utilizing a cantilevered roll design with a vertical tapered feed screw system, it consistently produces uniform compacted sheets with enhanced density. This equipment is ideal for applications including the production of Metformin tablets, Vitamin C tablets, and paracetamol granules.

With a processing capacity of up to 700 kg per hour and models like the GFC-1230 and GFC-1540, it caters to both small and large-scale production needs. The system is integrated with Smart-Safe™ containment options and optional inline PAT monitoring, facilitating seamless automation and data-driven operations.

Energy efficiency is emphasized with the inclusion of amp and watt displays for precise roll and screw operation. Material options ensure robust performance, while compliance with industry standards guarantees alignment with GMP and FDA regulations. Maintenance is simplified with quick-change design and easy cleaning features, particularly in the GFC-1230 model, which supports rapid changeovers.

For precise customization, the GFC GRANUFORCE™ offers scalable roll and screw designs across different development stages, backed by validatable process controls and optional automated control systems for enhanced production flexibility.

The post Dry granulation system for powder compaction appeared first on Making.com.

Compacts and Granulates Powders into Uniform Sheets

The GFC-LAB Micro GRANUFORCE™ from Freund-Vector is a compact benchtop roll compactor designed for precision granulation in pharmaceutical and nutraceutical applications. Utilizing a cantilevered roll design, it densifies and compacts powders into uniform sheets, ideal for producing supplements and vitamin granules. The system handles small processing volumes, ranging from 5g to 1kg/hr, making it suitable for laboratory and development settings.

Equipped with a vertical tapered feed screw and a standard serrated roll structure, this compactor ensures consistent material feed and sheet density. The roll gap is controlled via hydraulic pressure, mimicking production-scale models, thus aligning with engineered scalability requirements. Its inline de-aeration design enhances product quality by removing trapped air before compaction.

The GFC-LAB Micro GRANUFORCE™ features manual adjustment capabilities for roll force and speed, providing flexibility in operation. Its smart-safe containment options minimize dust emissions, maintaining a clean processing environment. Cleaning is straightforward with minimal tools needed, aided by a quick-changeover design to reduce downtime. Additionally, it runs on a single electrical connection, making it portable and convenient for different workspaces.

Ready for integration into existing laboratory and R&D processes, this compactor supports continuous and batch operations, facilitating easy transition from development to production. The equipment complies with stringent pharmaceutical standards, ensuring it meets industry-specific requirements for hygiene and safety.

The post Benchtop roller compacting system appeared first on Making.com.