Cultivates and Optimizes Microbial and Cell Cultures

The Desk Top Fermentor from Marubishi Bioengineering offers a versatile solution for biotech and pharmaceutical applications, accommodating various cell types from microbes to mammalian cells. Its unique hollowed bottom end plate facilitates accurate temperature control through mild heating and rapid cooling, ensuring optimal fermentation conditions. With interchangeable vessel sizes up to 10 liters, it provides full-scale fermentation capabilities in a compact form. Tailored for precision, it includes top or bottom entry driving systems and multiple stirring impellers to cater to different culture processes, such as aerobic and anaerobic fermentations. Ideal for producing biologics, vaccines, and enzyme supplements, this fermentor features a user-friendly interface, integration with bioprocess controllers, and options for data logging via USB. The equipment is energy-efficient, utilizing mass flow controllers for aeration and precise agitation systems. Available in materials that resist corrosion, it is suitable for harsh processing environments. The fermentor conforms to industry standards for quality and safety, offering seamless integration into existing production lines and easing operational challenges through its modular design and easy maintenance. Customizable features include pressure handling up to 0.2MPa(G) and optional automation enhancements, ensuring optimal performance across diverse fermentation applications.

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Sterilizes and Validates Pharmaceutical Components

The GSS P Steam Sterilizer from Getinge is engineered to meet the stringent demands of the pharmaceutical and biopharmaceutical industries. This autoclave stands out with its reliable contamination prevention and user-friendly operation. Employing a controlled steam sterilization process, it facilitates batch, high-speed, and continuous operations, perfectly suited for applications involving injectable vaccines, sterile saline solutions, and lyophilized drugs.

Designed with flexibility in chamber sizes ranging from 0.4 to 9 cubic meters, it integrates seamlessly into various production environments. The intuitive HMI and SIMATIC WinCC Unified enhance operator control and monitoring, promoting ease of use and safety. With materials crafted from GMP-compliant, sanitary stainless steel, the GSS P ensures hygiene and durability, while robotic welding and polishing guarantee superior finish and corrosion resistance.

Configured for global compliance, it supports GAMP5 validation and adheres to GMP standards, ensuring certification across diverse regulatory landscapes. The integrated Quality Process Management System facilitates seamless validation and monitoring, while options such as B & R, Siemens, or Allen Bradley control systems provide versatile automation and integration capabilities. Getinge further offers extensive customization and engineering support to optimize configuration and operational efficiency.

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Sterilizes Biopharmaceutical Products and Components

The FOF Saturated Steam Sterilizer by Fedegari is designed to meet the stringent requirements of the pharmaceutical and biopharmaceutical industries. This versatile sterilization solution excels in its ability to handle both solid and liquid products, such as vaccines, injectable drugs, and surgical instruments, with precision and reliability. Utilizing a sophisticated control system, the unit offers seamless integration into existing production lines, with both automatic and semi-automatic operations. Its stainless steel chamber, available in circular or square configurations, ranges from 200 to 6,800 liters and can be customized to fit specific throughput needs. The sterilizer ensures energy efficiency through optimized pressure control and maintains compliance with FDA and European standards, ensuring safety and reliability in critical applications. Maintenance is streamlined with Fedegari’s smart design, keeping downtime and operational costs low, while customizable engineering options allow for tailored solutions to your unique production requirements.

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Synthesizes, Distills, and Mixes Large-Scale Chemical Reactions

The QVF Universal-Reactor from De Dietrich Process Systems is your go-to solution for scaling up chemical reactions that exceed lab-scale capabilities. Designed for the pharmaceutical, fine chemicals, and specialty chemicals sectors, it allows for precise control in synthesizing active pharmaceutical ingredients, monoclonal antibodies, specialty polymers, and more. By employing a versatile, inert gas-compatible design, this reactor excels in handling liquid and gas processes under vacuum and EX-rated conditions. It facilitates seamless integration into existing lines with its robust, digitally controlled stirrer and OptiMix® baffle system, offering extraordinary mixing performance without splashing. Featuring a borosilicate glass construction and PTFE components, it ensures optimal chemical resistance and longevity. The reactor is equipped with CIP-nozzles, ensuring easy and reliable cleaning between batches, thus minimizing downtime. Compliance with European EX regulations guarantees safe operation in volatile environments. Whether for pilot studies or full-scale production, you can request custom configurations to best meet your specific operational needs.

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Opens Passive Valves for Sterilization Process

The Autoclave Passive Opener, by ChargePoint Technology, is engineered to effectively sterilize passive valves and integrated containers in pharmaceutical, biotech, and chemical industries. It stands out by securely opening passive units without requiring a full active assembly, using a hygienic tri-clamp option for secure docking within an autoclave. The design maximizes exposure of product contact surfaces through a unique ‘cruciform’ disc configuration, ensuring comprehensive sterilization during cleaning cycles. Compatible with valve sizes DN50 (2”) to DN200 (8”), this opener is constructed from corrosion-resistant PEEK and 316L or Alloy 22 materials, with FKM or FFKM seals for optimal chemical resistance. It supports GMP-compliant operations, allowing efficient drainage of condensate to maintain sterility assurance. Suitable for sterilization and containment of APIs, sterile powders, and biologic materials, it integrates seamlessly into manual and batch operations for demanding sterility and containment solutions.

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Inactivates Yeasts and Bacteria in Beverages

The C 8 Thermostabilizer from Cadalpe is engineered for beverage manufacturers seeking to ensure the biological stability of their products. This equipment excels in yeast and bacteria inactivation using a thermostabilization process and is suitable for beer, wine, spirits, and other beverages. Constructed with AISI 304 stainless steel and AISI 316 exchange plates, it ensures durability and sanitation. Its multi-stage operation allows for optional degassing and deoxygenation, enhancing product quality. The thermostabilizer is PLC-controlled for seamless integration into continuous, high-speed production lines. It supports CO2 saturation for certain applications, ensuring compatibility with carbonated products. Additionally, Cadalpe offers engineering support for customization, ensuring the equipment meets specific operational requirements.

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Propagates and Manages Yeast for Beverage and Food

The Yeast Plant from Bucher Unipektin offers a vital solution for beverage manufacturers and food producers requiring stringent control over yeast propagation. This system is engineered to operate under sterile conditions, ensuring the highest hygiene standards. The plant is designed for a flexible operation encompassing propagation, storage, pitching, homogenising, aeration, and the complete treatment process through autolysis and disposal. It excels in applications for producing baker’s yeast, brewer’s yeast, specialty ales, lagers, craft beers, and more.

Working on a continuous basis, the yeast plant integrates seamlessly into processing and final conditioning departments. It features various equipment groups, including specialized vessels for propagation, storage, and autolysis, all made to support efficient yeast management in liquid form. Each component is engineered for durability and compliance with high standards of cleanliness.

The system allows for tailored solutions with flexible design options to match specific operational requirements and is available with material selections optimizing corrosion resistance. Additionally, the integration of a full clean-in-place (CIP) mechanism facilitates easy maintenance, reducing downtime and risk of contamination. Bucher Unipektin provides customization and engineering support to ensure this yeast plant meets the precise needs of your production environment.

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Sterilises and Cools High Viscosity Liquids

The Scraped Surface Steriliser PE138 from Boema S.p.A. is engineered to address the complexities of sterilising high viscosity and particulate-containing liquids. Utilizing an innovative rotating shaft and swinging scrapers, it minimizes pressure on products, efficiently processing items like sauces and fruit purees. Capable of both vertical and horizontal installation, this modular system supports both heating and cooling phases, making it adaptable to various production needs. Its design allows for easy inspection and maintenance with quick disassembly seals and a hydraulic rotating shaft system. Ideal for aseptic preparations, the PE138 integrates seamlessly into continuous industrial processes, ensuring optimal performance in food, beverage, and nutraceutical sectors. Built with durable materials, it withstands rigorous operational demands while maintaining energy efficiency in processing high-capacity outputs.

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Deactivates and Sterilizes Contaminated Wastewater

The Killtank Wastewater Decontamination System, offered by Bioengineering AG, is designed to address the critical production need for the deactivation of pathogenic and genetically modified organisms in wastewater. This system employs a combination of batch or continuous heat sterilization processes to ensure thorough decontamination, adhering to local regulatory standards.

Ideal for biopharmaceutical manufacturers, research labs, and wastewater treatment facilities, the Killtank system plays a vital role in producing sterile effluents and safeguarding the environment. It features automated controls for both batch and continuous modes, integrating seamlessly into existing processes with options for manual operation where needed.

The system incorporates heat exchangers capable of pre-heating wastewater to 100°C and then elevating temperatures to 140°C for complete inactivation, followed by rapid cooling. Additionally, energy efficiency is enhanced through a built-in heat recovery system.

Constructed from materials that offer superior corrosion resistance, the Killtank is compliant with stringent safety and environmental standards, making it a reliable choice for managing biohazardous waste. Maintenance is simplified with an integrated Cleaning In Place (CIP) system, facilitating quick, contamination-free cleaning and ensuring minimal downtime.

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Processes and Deactivates Enzymes in Fruit and Vegetable Purees

The EOS TT LINE from Bertocchi provides a comprehensive cold extraction process designed for the production of high-quality fruit and vegetable purees. This system features tube-in-tube enzymatic deactivation, reducing mechanical and thermal stress to maintain product integrity in terms of texture, color, and consistency. Ideal for food and beverage manufacturers, fruit processors, and baby food producers, the EOS TT LINE efficiently processes a wide range of purees including apple, banana, and carrot, among others.

Capable of handling up to 12 tons per hour, the EOS TT LINE excels in continuous, high-speed operations. With a complete lineup of integrated systems including turbo extractors, enzyme deactivators, and both cold and hot deareators, it ensures seamless production line integration. The energy-efficient design reduces operational costs, while the automation allows precise process control. Constructed with durable materials for longer lifecycle and reduced maintenance needs, this equipment demonstrates reliability and a readiness to adapt through customization and engineering support tailored to specific operational needs.

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