Generates On-Demand High-Purity Hydrogen for Laboratory Use

The H-Genie® from ThalesNano is a compact and innovative solution designed for laboratory environments requiring on-demand hydrogen generation. This system stands out by eliminating the need for traditional gas cylinders, producing hydrogen directly from deionized water at high purity levels of 4.0 grade. It operates at pressures up to 100 bar, supporting diverse applications in fine chemicals, pharmaceuticals, and petrochemicals. With a flow rate adjustable up to 1 NL/min, it’s particularly effective for processes such as hydrogenation and catalyst screening. The unit’s versatility is enhanced by its compatibility with various reactors and its integration into both benchtop and automated setups. Designed with safety in mind, the H-Genie® includes an internal hydrogen detector and data monitoring capabilities, providing real-time system status through convenient data export. Its compact design minimizes the laboratory footprint, while its robust engineering ensures reliable performance under demanding conditions, compliant with stringent laboratory safety standards.

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Generates On-Demand Hydrogen for Laboratory Applications

The H-Genie Lite from ThalesNano is a compact hydrogen generator designed for laboratory environments, offering a safe and efficient solution for hydrogenation processes in chemical, pharmaceutical, and research labs. Generating hydrogen on-demand up to 50 bar, it eliminates the need for conventional cylinders, saving space and ensuring safety with built-in leak detectors. Its intuitive touchscreen interface allows quick setup and operation, making it suitable for pharmaceuticals, fine chemicals, and isotopically labeled compounds production. The H-Genie Lite’s compact design fits standard fume hoods, streamlining integration into existing lab setups, and operates using deionized water, ensuring high purity output with minimal consumption.

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Controls and Automates Flow Chemistry Reactions

The THS System Controller and ReAction Software from ThalesNano offer an advanced solution for laboratory automation and precision in the chemical and pharmaceutical sectors. This system facilitates seamless remote control and monitoring of flow chemistry reactors, integrating various modules such as reactors, hydrogen generators, and HPLC pumps for comprehensive process management. The software allows for individual parameter control, supporting diverse reaction types including hydrogenation, carbonylation, and photochemistry, making it ideal for producing active pharmaceutical ingredients, specialty chemicals, and other end-products. Compatible with existing lab setups, it provides real-time data logging and safety management features, including automated shutdowns and parameter adjustments. Designed for continuous and automated operations, the system supports both bench-top and remote control, enhancing operational efficiency and experimental reproducibility across multiple industries, including pharmaceutical, chemical, and biotech.

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Generates and Mixes Hydrogen for Flow Reactions

The H-Cube® Pro Hastelloy from ThalesNano is a continuous flow hydrogenation reactor designed for researchers and manufacturers in the pharmaceutical and fine chemical industries. This reactor stands out for its on-demand hydrogen generation from water via electrolysis, eliminating the need for external hydrogen cylinders. Its unique design features Hastelloy C wetted parts, providing superior chemical resistance essential for handling corrosive reagents like mineral acids and bases, as well as oxidizing agents.

Operating within a temperature range of 10 to 150°C and a pressure range up to 100 bar, the H-Cube® Pro Hastelloy efficiently manages hydrogenation processes with fine control over reaction conditions such as pressure, temperature, and flow rate. The integrated microHPLC pump ensures accurate solvent delivery, which, when mixed with hydrogen, supports a stable reaction environment.

Ideal for producing active pharmaceutical ingredients, custom fine chemical compounds, and specialty polymers, this reactor accommodates reactions with variable scales from milligrams to grams. Its pre-packed CatCart® columns simplify catalyst handling, enhancing throughput and reducing downtime. Suitable for bench-top operations, this equipment is a versatile solution for R&D and processing departments seeking reliable performance in complex hydrogenation applications.

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Generates Hydrogen and Facilitates High-Pressure Chemical Reactions

The Phoenix-H-Genie Hydrogenation Platform from ThalesNano offers a cutting-edge solution for chemical and pharmaceutical sectors, enabling seamless hydrogenation processes without the need for external hydrogen supplies. By generating hydrogen through the electrolysis of water, this system ensures on-demand, safe production up to 1 NL/min at pressures of up to 100 bar. Designed with versatility in mind, it accommodates both homogeneous and heterogeneous catalysts, operating at temperatures reaching 450°C.

Its modular nature means you can tailor configurations for specific lab setups, with components such as HPLC pumps and mixer modules enhancing its capabilities. This platform is particularly valuable in producing synthetic fuels, pharmaceuticals, and specialty chemicals, supporting continuous and scalable operations. The integrated mass flow controller provides precise monitoring, optimizing both reaction conditions and efficiency. The use of self-fillable Catcarts enables catalyst testing and synthesis in varied quantities, making it ideal for fine chemical and pharmaceutical research. Configured from durable materials and offering easy maintenance, the Phoenix-H-Genie ensures long-lasting performance in demanding chemical environments.

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Facilitates Safe Catalyst Handling and Efficient Reactions

ThalesNano’s CatCarts® offer a unique catalyst handling system designed for flow chemistry applications, providing a safe and efficient way to manage heterogeneous catalysis with minimal user contact. These stainless-steel cartridges are packed with a solid catalyst and feature an integrated filtration system to ensure only the liquid substrate passes through, eliminating the need for catalyst filtration. Compatible with the H-Cube® series and Phoenix flow reactors, CatCarts® excel in hydrogenation reactions where precise control and high reaction rates are crucial.

They are ideal for industries ranging from pharmaceutical manufacturing to chemical research, facilitating the production of APIs, specialty chemicals, and selective hydrogenation compounds. CatCarts® are available in various sizes to match your specific chemistry needs and allow for quick catalyst exchange and reuse, reducing downtime and increasing productivity. The system’s design enhances phase interaction, boosting mass transfer and reaction speed while allowing seamless integration into existing production lines. Customize your CatCarts® with the desired catalyst through ThalesNano’s custom loading service, ensuring the perfect fit for your process requirements.

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Generates On-Demand Hydrogen for Catalytic Reactions

The H-Cube® Mini Plus from ThalesNano offers a unique solution for laboratory-scale continuous flow hydrogenation. This compact system generates hydrogen on-demand through water electrolysis, eliminating the need for stored gas cylinders. It supports a range of catalytic reactions crucial in pharmaceuticals, fine chemicals, and agrochemicals, such as the production of antihypertensive drugs and active pharmaceutical ingredients. With its ability to operate from atmospheric pressure to 100 bar and temperatures up to 100°C, the H-Cube® Mini Plus ensures precise control over reaction conditions. The system’s automation features include an integrated video tutorial, making it user-friendly for research and development departments. Adaptable across liquid, gas, and solid product types, it maintains energy efficiency with its controlled operation. The use of CatCart® cartridges simplifies catalyst handling and enhances safety. Configurable for various scales, it is optimal for both experimental and small-scale production needs.

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Generates and Mixes Hydrogen for Chemical Reactions

The H-Cube® Pro from ThalesNano combines electrolytic hydrogen generation with precise reactor control for seamless integration into laboratory-scale chemical synthesis. Using an on-demand electrolysis system, it safely generates up to 60 NmL/min of hydrogen gas, eliminating the need for external hydrogen cylinders and enhancing laboratory safety. The reactor is designed for pharmaceutical, fine chemical, and agrochemical applications, facilitating reactions such as hydrogenation, reduction, and deuteration. It offers scalability from milligram to gram-scale production, making it suitable for R&D and bench-top laboratory operations.

Equipped with user-friendly software, the H-Cube® Pro allows real-time monitoring and parameter adjustment, improving reaction control and efficiency. The system’s versatility is enhanced with additional modules, such as the Phoenix Flow Reactor, enabling operations up to 450°C for more complex synthesis routes. Its design minimizes energy and solvent consumption through efficient reaction parameters and customizable hydrogen flow rates. Suitable for use with a variety of gases beyond hydrogen, when connected to the Gas Module, it widens chemical capabilities significantly.

Constructed from corrosion-resistant materials, the H-Cube® Pro maintains robustness and reliability across a range of chemicals. Its compact design, combined with flexible automation options like integration with an Autosampler system, supports optimization studies and high-throughput screening with minimal manual intervention. With potential custom configuration and ongoing support, ThalesNano’s reactor system enhances productivity in laboratories needing high-precision, continuous flow chemistry solutions.

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