Mixes and Granulates Small Batch Products

The P100 High-Shear Mixer Granulator from DIOSNA is an essential solution for industries like food, pharma solids, cosmetics, feed, and fine chemicals, where precise mixing and granulating are crucial. This compact unit excels in producing even mixtures and granulates across smaller batch processes, covering 30% to 90% of its total 120-liter volume. The mixer is designed with highly efficient mixing tools and a vessel geometry that promotes optimal product flow. It integrates seamlessly into various production settings, whether placed freely or against a technical zone wall, complying with ATEX requirements for safe operations under inert conditions. Known for its energy-efficient operation, the P100 is pressure shock resistant and includes features for easy cleaning, such as a swing-open spout housing. Ideal for producing granulated sugar, pharmaceutical tablets, face cream bases, and more, it adapts reliably to your production demands with flexible installation options and sturdy design.

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Mixes, Granulates, and Pelletizes Laboratory Batches

The P 1-6 high-shear mixer granulator from Diosna offers a compact, efficient solution for laboratories and R&D departments in the pharmaceutical, food, cosmetics, and fine chemical industries. This versatile equipment excels in mixing, granulating, and pelletizing diverse formulations, from sustained-release tablets and effervescent tablets to skincare creams and instant soup mixes. Its cylindrical-conical mixer geometry and high-shear design ensure perfect homogeneity and optimal active pharmaceutical ingredient (API) distribution across solid, wet, or hot melt granulations.

Designed with intuitive handling, the P 1-6 features a plug-and-play setup, facilitating easy operation without specialized tools, enabling swift scale-up from laboratory to production environments. Compatible batch sizes range from 0.04 to 2.7 kg, with bowl capacities of 0.25 to 6 liters, catering to both small-scale experimental and pilot-scale productions. The chopper speed is adjustable from 220 to 2,200 rpm, allowing precise control over particle size and distribution.

The P 1-6 can be equipped with an optional spheronizer to further enhance pellet production capabilities. Its robust build offers a high level of cleanliness and efficiency, ensuring compliance with industry standards for safe, contamination-free processing. With continuous innovation and optimization, Diosna ensures that the P 1-6 remains a reliable cornerstone for modern laboratory processing, offering customizable configurations to meet specific research needs.

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Mixes and Granulates Pharmaceutical Solids

The P 250-1250 from DIOSNA is a production-scale mixer granulator designed to master the challenges of pharmaceutical and chemical manufacturing. This piece of equipment excels in efficiently mixing and granulating pharmaceutical solids, combining robust high-shear technology with versatile application capability. It supports a variety of end-products, from tablet formulations and starter cultures to specialty chemical blends.

Working through a closed system, the DIOSNA mixer granulator optimizes the processes of mixing and granulation, ensuring consistent, high-quality outputs with each batch. The integrated DIOSNA-Toollift allows seamless inspection of shaft seals, simplifying maintenance and reducing downtime.

Engineered for seamless integration, it operates with advanced automation, including an integrated industrial PC that ensures data integrity and compliance with 21 CFR Part 11 standards. Easily adaptable, this equipment offers automated cleaning features and effective remote service capabilities for streamlined operations and reduced labor costs.

Crafted from corrosion-resistant materials, it meets global GMP standards, providing long-lasting reliability in demanding production environments. Whether you are in pharmaceuticals, food, cosmetics, feed, or fine chemicals, the P 250-1250 ensures your production line remains efficient and consistent.

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Mixes and Granulates Solid and Liquid Mixtures

The V10 – V100 from DIOSNA is a versatile universal mixer granulator designed for industries such as food, pharmaceuticals, chemicals, plastics, and cosmetics. What sets this equipment apart is its ability to combine mixing and granulating through spray technologies, ensuring uniform and reproducible particle sizes. The equipment accommodates a range of applications, including spice blends, pharmaceutical tablets, and cosmetic pigments. With a compact cylindrical-conical design, it offers easy operation through push-button controls and timers. This robust mixer handles batch, manual, pilot, and entry-level operations, supporting both solid and liquid product types. Available from 11.5 to 180 liters, the machine aligns with your production needs, ensuring efficient integration into existing processing lines. Built for durability, it supports a wide array of end-products like polymer additives and herbal extracts while optimizing energy usage through its powerful, adjustable chopper.

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Mixes and Granulates Industrial Scale Batches

The V250 – V1600 Universal Mixer Granulator from DIOSNA Dierks & Söhne GmbH offers robust and versatile mixing capabilities for industrial manufacturing. This equipment’s vertical design incorporates a cylindrical container with a conical top, a three-bladed bottom mixing tool, and a side-mounted chopper. It is ideal for blending food, pharmaceutical, cosmetic, and chemical materials, including bakery doughs and pharmaceutical granules. The V250 – V1600 accommodates volumes from 210 to 1,400 liters, supporting large-scale production with swift processing times. It features easy-to-use push-button controls and a compact, low-profile construction for seamless integration into existing production lines. Equipped with low-wear air gap seals and a large emptying valve, it ensures efficient operation and maintenance. Available in materials suitable for various industrial applications, the mixer granulates efficiently while meeting industrial compliance and offering customization and engineering support.

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Granulates, Dries, and Coats Pharma, Cosmetics, and Chemicals

The Minilab RC from DIOSNA Dierks & Söhne GmbH is a versatile benchtop unit designed for R&D environments in pharmaceuticals, cosmetics, and fine chemicals. Its unique Rapid Change system allows seamless transitions between fluid-bed processing and drum coating, enabling efficient granulating, drying, and coating workflows. The unit features a transparent design for easy process monitoring and full control via an integrated graphic display. Applications include producing granules, face powder, and enteric-coated tablets. With bowl sizes ranging from 1 to 7 liters and batch capacities tailored for precise formulation, this equipment offers flexible operation for small-scale production trials. It boasts tool-free disassembly for easy cleaning and maintains a compact footprint for lab settings. The Minilab RC operates under strict compliance with GMP standards, ensuring quality and safety in your research processes.

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Kneads and Mixes Varied Dough Types Efficiently

DIOSNA’s PSPV 160A and 240A spiral kneaders provide an exceptional solution for dough processing across various applications. Constructed from premium stainless steel, these kneaders are designed to ensure thorough mixing and kneading of diverse doughs, including wheat, mixed bread, and wholemeal varieties. With capacities of up to 240 kg, these machines cater to both small and medium-sized businesses as well as industrial kitchens, enhancing production efficiency while maintaining high-quality end products like baguettes, ciabatta, and sourdough breads.

The spiral kneaders feature a robust design, offering either mobile or stationary operation with an extendable bowl, simplifying integration into existing production lines. The equipment is equipped with programmable logic controllers, allowing operators to easily manage and store process parameters for repeatable results. Furthermore, optional temperature and energy controls enhance operational precision and economic efficiency.

Constructed with easy-to-clean smooth surfaces and optional stainless steel fittings, these kneaders comply with high hygiene standards demanded by the food industry. DIOSNA also provides various customizable options, such as integrated temperature sensors or bowl wall scrapers, to meet specific operational requirements.

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Kneads and Mixes Dough Efficiently

The W 160-400 A from DIOSNA offers a versatile solution in kneading and mixing processes, tailored for artisanal and industrial food producers. This wendel mixer is distinct due to its unique opposing twin-tool design, which significantly reduces kneading times and minimizes dough heating, enhancing dough quality and consistency. Ideal for a wide range of applications, it efficiently processes bread, pastry, pizza, and cake doughs, as well as pharmaceutical granules and cosmetic creams.

The W 160-400 A accommodates batch capacities from 160kg to 400kg, integrating seamlessly into both small and large-scale production lines. Its PLC-controlled system ensures precise operation, and options for stainless steel construction enhance durability and hygiene. With reduced energy consumption from its optimized motor system, this mixer offers improved water absorption, granting you superior dough properties. Maintenance is simplified with its high ground clearance, allowing easy cleaning, and its compliance with industry standards ensures reliable performance across various sectors.

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Kneads and Mixes Doughs and Solids Efficiently

The WH 240-600 E/A from Diosna is a premium wendel mixer designed for rigorous hygiene standards and versatile mixing needs across food, pharmaceutical, and cosmetic industries. Its open frame with stainless steel construction minimizes contamination risks and simplifies cleaning, adhering to the European Hygienic Engineering & Design Group guidelines. Featuring oppositely rotating wendel tools, it delivers gentle dough kneading with minimal heat generation, ensuring optimal dough texture for products like bread, pastries, and pizza doughs.

Capable of handling batch capacities from 240kg to 600kg, this mixer suits diverse production scales and integrates seamlessly into existing lines with options for either movable bowls or under-bowl discharge systems. All electric operations eliminate hydraulic-related maintenance issues, enhancing reliability. Specifically engineered for the production of pharmaceutical tablets, face creams, and animal feed, it excels in wet cleaning efficiency due to its low-pressure compatibility, reducing downtime while maintaining cleanliness. Diosna offers options for configurations tailored to specific requirements, backed by compliance with leading industry standards.

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Mixes, Granulates, and Dries Pharmaceutical and Food Products

The CCS Granulation Line from DIOSNA is designed to optimize your pharmaceutical and food processing needs. This system seamlessly integrates mixer-granulation and fluid bed processing, allowing for efficient wet granulation followed by precise drying. Capable of producing pharmaceutical tablets, cosmetic cream bases, and nutrient-rich granules, it facilitates everything from yeast-based pre-doughs to specialty chemical granules.

Utilizing a through-the-wall installation, it ensures a strict separation of production and technical areas, promoting operational hygiene and workspace efficiency. With automation in mind, the system is equipped with PC control that complies with 21 CFR Part 11, paired with remote maintenance capabilities to support uninterrupted production.

The CCS Granulation Line is designed to meet stringent safety standards and withstand pressure shocks of up to 12 bar, adhering to ATEX regulations. Its energy-efficient design reduces operational costs while maintaining high throughput, suitable for both pilot and full-scale production. With flexible container sizes and an intuitive interface, it accommodates varied batch sizes effortlessly, ensuring your production line meets evolving demands.

Furthermore, the system supports recipe creation and comprehensive data acquisition, documented with compliant software, enhancing your quality control processes. Available with customizable options, it can be tailored to fit specific application needs, including special solutions for containment in pharmaceutical settings, ensuring your operations are both efficient and compliant with industry standards.

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