Facilitates Dosing and Assembly of Medical Devices

The FRT Rotary Indexing Dosing and Assembly Platform from Harro Höfliger is a compact, versatile solution ideal for pharmaceutical and medical device manufacturers. It efficiently handles dosing, filling, and assembly processes using precise rotary indexing technology. The FRT is adept at assembling inhalers, cartridges, and diagnostic products within a limited space, ensuring seamless integration into existing production lines.

Equipped with sophisticated dosing methods and control systems, the FRT supports both fully automatic and semi-automatic operations, achieving up to 60 cycles per minute across multiple lanes. Designed for high-speed operations, it offers compliance with cleanroom standards up to class A 100,000 – 100, making it suitable for sensitive environments.

The platform incorporates barrier technology for operator and product safety, especially when dealing with highly active and toxic substances. Available in various materials to ensure chemical compatibility and featuring integrated containment systems, the FRT meets rigorous industry standards such as GMP and FDA compliance.

Efficient parts handling, enabled by vacuums, grippers, or tongs, allows for accurate component transfer and assembly. Additionally, Harro Höfliger offers customization options and engineering support to tailor the system to specific production needs, ensuring optimal performance and integration.

The post Rotary indexing table for dosing and assembly appeared first on Making.com.

Assembles and Inspects Medical and Pharmaceutical Products

The MRT Round Motion Assembly Platform from Harro Höfliger stands out for its compact, high-speed assembly of medical and pharmaceutical products. Utilizing precise rotary motion, this platform combines automated assembly, inspection, and dosing processes to efficiently produce metered-dose inhalers, diagnostic test strips, and transdermal delivery systems. The MRT’s modular design supports scalable production, integrating seamlessly with existing lines and upstream or downstream equipment. Capable of operating in clean room conditions (Class 100,000), it meets stringent regulatory requirements for pharmaceutical manufacturing. With options for electro-pneumatic or servo-motor control, it ensures both flexibility and precision in assembly operations. The MRT also minimizes space requirements while offering high throughput, reaching up to 80 cycles per minute, making it an ideal solution for manufacturers in the pharmaceutical and medical device industries seeking robust, customizable assembly solutions.

The post Round motion assembly platform for inhalers appeared first on Making.com.

Forms, Fills, Seals, Cuts, and Inspects Blisters

The MSP Blister Filling Machine from Harro Höfliger represents a robust solution for pharmaceutical and medical device manufacturing, offering precise control over blister forming, filling, and sealing processes. Utilizing either drum or membrane dosing, it ensures accurate micro-dosing of powders. Ideal for producing diverse end-products such as aluminum blister strips for inhalers, aseptic blister packs, and transdermal patches, it delivers extensive application versatility. The MSP’s drum dosing achieves outputs of up to 576 fill volumes per minute, while membrane dosing reaches 2400. Its compact design integrates seamlessly into production lines, complemented by downstream assembly and packaging equipment. With integrated barrier technology and X-ray inspection systems, it promotes both operator safety and product quality, fully compliant with GMP and FDA standards. The machine’s ergonomic design allows easy operation and maintenance, featuring a range of customizable options to meet specific production needs.

The post Commercial blister filling solution for dry powder appeared first on Making.com.

Forms, Fills, and Seals Micro-Dosed Blisters

The SSP2 from Harro Höfliger is a compact micro-dosing blister packaging machine designed for precision filling in pharmaceutical and medical device production. It specializes in forming, filling, sealing, cutting, and winding small-batch dry powder inhalers and diagnostic reagent cartridges. The machine allows for flexible production with drum and membrane dosing options for partial or complete cavity fills. It can process 144 fills per minute using drum dosing and up to 900 with membrane dosing across a web width of 150 mm. The SSP2 seamlessly integrates with existing production lines, offering automation and ease of use, while ensuring operator safety with its containment features. Its compact design requires minimal set-up space and continuous inspection guarantees consistent product quality. Available in materials that comply with GMP standards, it also facilitates easy maintenance and cleaning with ergonomic accessibility.

The post Micro-dosing system for inhalation blisters appeared first on Making.com.

Integrates Dosing, Filling, and Assembly Operations

The LOT Oval Motion Machine from Harro Höfliger is designed for the seamless integration of dosing, filling, and assembly processes within pharmaceutical and medical device manufacturing. This modular platform supports complex assembly tasks, providing precision in applications ranging from drug delivery devices and inhalers to eye care products and nasal dispensers. The machine accommodates cleanroom environments, with options for classes D to A, and operates at speeds of up to 60 cycles per minute. Its fully automatic setup allows for thorough inspection capabilities, including leak tightness and flow inspections, ensuring high-quality output. The compact design incorporates barrier technologies for operator protection and product integrity, and supports various welding and hemming techniques using thermal, laser, and ultrasonic methods. With its flexible configuration, the LOT Oval Motion Machine is GMP compliant and offers a customizable approach to meet specific production needs, featuring integrated film handling and labeling systems.

The post Liquid dosing and assembly platform for pharmaceutical products appeared first on Making.com.

Fills and Assembles Drug Delivery Systems

The Pharma Custom Automation Solution by Comecer offers a specialized system for filling and assembling drug delivery devices and single-use disposables. This equipment stands out for its ability to handle complex and hazardous materials safely, integrating seamlessly into your aseptic processing line. It utilizes precise microdosing and dispensing techniques for high-potency ingredients, ensuring accuracy and safety. Primarily utilized in biopharmaceutical and pharmaceutical industries, it can efficiently produce end-products such as prefilled syringes, sterile IV solutions, and biologics. With robotics and barrier systems, it maintains sterile environments while facilitating high-speed operations. Designed for compliance with GMP and FDA standards, it offers flexible configurations to meet your unique production needs, supported by comprehensive engineering support and customization options.

The post Custom automation for drug-device filling and assembly appeared first on Making.com.

Fills and Closes Liquid Pharmaceutical Containers

The FVC 50606 from Bausch+Ströbel is an automated CombiSys filling and closing machine, designed for high-precision aseptic processing in pharmaceutical and biotech settings. This system is distinguished by its modular design and capability to handle up to 12,000 containers per hour. It automates dosing, filling, and closing tasks with integrated dosing systems for maximum efficiency, minimizing waste with the Zero Reject Principle. The machine is equipped with 100% IPC at full output, meeting all relevant GMP and FDA compliance standards. Its robust design supports RABS and isolator environments to ensure sterile conditions. With easy-to-use operational controls and quick set-up times, it provides seamless integration into existing production lines. The CIP/SIP system ensures thorough cleaning between batches without manual disassembly, enhancing productivity and reducing downtime. Customizable options, including various dosing system configurations, offer tailored solutions to specific production requirements.

The post Combisys filling and closing system for pharmaceutical containers appeared first on Making.com.

Fills, Seals, and Stoppers Vials, Syringes, and Cartridges

The TRUKING Flextron Series Nest Fillers are designed to meet the diverse challenges faced by modern pharmaceutical manufacturers. This equipment facilitates the seamless filling, sealing, and stoppering of vials, pre-filled syringes, and cartridges. Utilizing a fully servo-controlled and robotic design, it ensures high throughput with minimal breakage, processing up to 36,000 units per hour. Its versatility enables handling multiple formats in a single unit, optimizing efficiency across various formulations including biologics and IV solutions.

Automation is enhanced with features like automatic de-bagging and vacuum stoppering, promising precise and bubble-free end products. The system offers in-house OEL 5 containment within custom C-RABS and Isolators for maximum safety and compliance with stringent GAMP, cGMP, and FDA standards. An industrial PC controls operations, ensuring comprehensive data integrity and remote access.

Construction incorporates superior SS 316L for product contact parts, enabling effective cleaning with built-in CIP & SIP systems. Customizable footprints and modular designs are available to fit specific cleanroom requirements, providing an ideal solution for biopharmaceutical applications, including insulin and vaccine production. The TRUKING Flextron Series does more than fill—it integrates performance with compliance, efficiency with precision.

The post Nested fillers for vials, pre-filled syringes, and cartridges appeared first on Making.com.

Removes Pyrogens and Sterilizes Containers

The TRUKING Depyrogenization Tunnel is an essential solution for aseptic processing needs, leveraging advanced sterilization expertise to ensure optimal pyrogen removal. This cutting-edge tunnel utilizes state-of-the-art sterilization techniques, including a validated pressure differential system to maintain sterile conditions throughout the process. Designed to support biopharmaceutical and pharmaceutical tablet production, it ensures sterile manufacture of products like prefilled syringes, ampoules, and intravenous therapy bags.

Featuring a unique CNC-designed mesh belt and an auto wash-in-place system, it offers automatic cleaning and long-term operational reliability. With precise HEPA filter loading and negative pressure diversion technology, contaminant prevention is guaranteed. The tunnel supports automation and integration through IPC control, enabling audit trails and data integrity features compliant with 21 CFR Part 11.

Engineered for energy efficiency, the tunnel minimizes utility usage while maintaining strict compliance with GAMP, cGMP, and FDA regulations. It comes ready for customization with various material options, suited for diverse chemical processing environments, ensuring long-lasting performance and reducing maintenance downtime.

The post Sterilizing and depyrogenization tunnel for ampoules appeared first on Making.com.

Fills and Seals Ampoules for Pharmaceuticals

The Ampoule Filling and Sealing Machine from TRUKING TECHNOLOGY LIMITED offers pharmaceutical manufacturers and biotech companies a fully servo-driven solution for precise ampoule production. Utilizing state-of-the-art volumetric filling technology, it ensures dosing accuracy within ±0.5% to ±1%. This machine operates with an innovative walking beam design that minimizes vibration for superior sealing quality, even at high speeds. Applications include the production of insulin, vaccines, and antibiotic injectable liquids. With an industrial PC control system, it enables remote access and complies with 21 CFR Part 11, ensuring data integrity and audit trail capabilities. The compact ergonomic design supports seamless integration into existing production lines, while its customizable configuration caters to specific floor plan requirements. Additionally, it features an online CIP-SIP system for efficient cleaning and sterilization, making it suitable for aseptic processing environments. The equipment’s construction from SS316L and its progressive inert gas purging system further assure product quality by maintaining an oxygen residue of less than 1%.

The post High-speed ampoule filling unit appeared first on Making.com.