Granulates and Mixes Pharmaceutical Powders and Granules

The ROTO MIX from IMA Group is a high shear mixer granulator specially designed for the pharmaceutical industry, facilitating superior mixing, granulation, and agglomeration of powders. Inspired by proven Roto technology, it excels in achieving uniform granule size and cohesion, crucial for tablet and capsule production. Its unique impeller design minimizes product sticking, maximizing yield and maintaining a dust-free environment for safe solvent use. The versatile ROTO MIX is perfect for producing paracetamol granules, ibuprofen tablets, and vitamin supplements, supporting both batch and high-speed continuous operations. With bowl capacities ranging from 60 to 2,500 liters, it integrates smoothly into your production line, offering options for through-the-wall installation to optimize space. Its energy-efficient operation and Wash-In-Place system enhance cleanliness and reduce downtime, while compliance with GMP standards ensures it meets rigorous industry regulations. Plus, customization in impeller power and chopper speed allows adjustment to specific production needs.

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Processes and Granulates Liquids, Solids, and Powders

The AGT® Series Fluid Bed Granulators from Glatt Ingenieurtechnik offer versatile solutions for the granulation, drying, and coating of a wide range of products across food, chemical, and pharmaceutical industries. These systems efficiently transform liquids and solids into uniform granules through continuous or batch processing. The fluid bed technology, integrated with interchangeable process chambers, allows for maximum flexibility while handling temperature-sensitive materials with care. Equipped with PLC-controlled automation, this series ensures precise control and integration within existing production lines. The AGT® systems, available in different models like AGT®2700 and AGT®1600, excel in applications from food additives to active pharmaceutical ingredients, offering reliable processing with optional configurations to suit specific production needs. Enhanced energy efficiency and built-in CIP systems streamline operations and maintenance, ensuring compliance with industry standards.

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Processes and Granulates Powders into Uniform Granules

The GMXB-LAB Micro GRANUMEIST® by Freund is a lab-scale high shear wet granulator, integral to transforming powders into consistent, high-density granules for pharmaceutical, biopharmaceutical, and fine chemical applications. Its bottom-drive design ensures easy maintenance and user safety, while interchangeable product bowls provide flexibility across 1L to 6L batches. This granulator handles mixing and homogenizing processes with precision, supported by a peristaltic pump for both aqueous and solvent-based operations. The system also features user-defined speed settings and optional Smart-Safe™ containment for controlled environments. The integration of a color touchscreen control and USB data collection facilitates streamlined operations and process validations, ensuring compliance with industry standards.

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Processes Powders into Granules and Coated Tablets

The GMXB-LAB Mini GRANUMEIST® from Freund is a state-of-the-art high shear wet granulator designed for efficient and homogeneous granulation processes in pharmaceutical, chemical, biotech, and food industries. Its bottom-drive system allows for easy cleaning, maintenance, and user safety. The unit utilizes interchangeable product bowls (4L, 6L, and 10L) and user-defined mixer and chopper blade speeds, enhancing process flexibility. It’s ideal for producing paracetamol tablets, vitamin supplements, and more.

Offering integrated peristaltic pumps and optional jacketed and vacuum-drying bowls, it supports both aqueous and solvent processing. This makes it versatile in operations like wet granulation, mixing, drying, and coating. With a proportional mixer blade tip speed and bowl and blade geometries, it scales easily from lab to pilot operations. A color touchscreen gives you validatable process control with multiple endpoint detection parameters like mixer power and granulation time.

The GMXB-LAB Mini GRANUMEIST® ensures compliance with industry standards while offering customization options and engineering support for tailored solutions. The quick-changeover design requires no tools, minimizing downtime and ensuring efficient production cycles.

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Facilitates Wet Granulation and Mixing

The GMX-LAB Micro GRANUMEIST® from Freund-Vector is a high shear granulator designed to deliver efficient wet granulation and homogenous mixing. Its top-drive design simplifies cleaning and maintenance, while ensuring faster processing times without compromising user safety. With a range of applications, including pharmaceuticals and nutraceuticals, it can produce immediate and extended-release tablets, as well as multivitamin and enzyme supplements.

The system features interchangeable 1L and 4L bowls, offering flexibility for varying batch sizes, and integrates user-defined settings for mixer and chopper blade speeds. Equipped with an optional jacketed bowl for product temperature control and an integrated peristaltic pump for precise solution addition, it ensures consistent granule formation. The Smart-Safe™ containment option enhances operational safety, while the proportional mixer blade tip-speeds and customizable bowl and blade geometries optimize processing outcomes.

Its color touchscreen control system simplifies operation, and the process control is designed for validation, supporting multiple end-point detection parameters. The unit supports scalability with its modular design and comes equipped with a USB data collection port for process monitoring. This portable and self-contained system is ideal for bench-top and pilot-scale operations in R&D and laboratory settings within pharmaceutical, biotech, and chemical industries.

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Processes Powders into Uniform Granules

The GMX-25 Granumeist from Freund is a high shear granulation mixer meticulously designed to enhance your wet granulation process. Its top-drive mechanism simplifies cleaning and maintenance, promoting user safety and efficiency. Highly adaptable, this system features user-defined mixer and chopper speeds, and an integrated peristaltic pump for precise liquid addition. Ideal for pharmaceutical manufacturers, it effectively processes powders into granules, perfect for tablets and supplements. The GMX-25’s flexible design includes both aqueous and solvent processing capabilities, with an optional jacketed bowl for temperature control. Mounted on casters for portability, it incorporates a vertical shaft chopper and tip cart for easy handling. Compliant with industry standards, it supports both automatic and manual operations, offering batch and pilot scalability. Its Smart-Safe™ containment and optional advanced COMPUTM automation ensure process validation and data integrity under 21 CFR Part 11 compliance.

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Integrates Processes for Small-Scale Production

The AR 403 from ERWEKA GmbH is a highly adaptable modular processing unit designed for small-scale production and R&D in pharmaceuticals, cosmetics, and food industries. It features a robust three-phase AC motor offering torque up to 23 Nm, with electronic speed control ranging from 20 to 400 rpm. This unit excels in tasks including mixing, grinding, coating, and pelletization, accommodating diverse end-products such as effervescent tablets and eye shadow bases. The modular design allows for easy integration of various attachments like coating pans and pelletizers, enhancing versatility. Constructed with maintenance-free worm gear drives, the AR 403 ensures reliability and efficiency, while its compact size fits seamlessly into bench-top operations. Compliance options are available with IQ/OQ/PV documentation, making it suitable for GMP-compliant environments.

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Processes Wet Granules for Consistent Particle Size

The Wet Granulator FGS II from ERWEKA GmbH enhances pharmaceutical and chemical production by ensuring precise granule size through its oscillating rotor design. This granulator is ideal for creating uniform effervescent tablets and vitamin granules, accommodating a variety of material sieves from 0.315 mm to 3.15 mm to achieve desired particle sizes. Capable of processing up to 30 kg/h, the equipment integrates smoothly into manual or batch processing lines, suitable for pilot operations. Constructed with stainless steel components, it guarantees durability and compliance with industry standards. Safety features, like the emergency stop function, and optional specialized sieves allow for customization to meet specific production needs.

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Mills and Granulates for Uniform Particle Size

The MultiMill from SSPM Systems & Engineers Pvt. Ltd. is an expertly engineered milling solution for the pharmaceutical, nutraceutical, chemical, and food industries. This machine stands out with its robust design, integrating a non-vacuum rated top drive mechanism to efficiently mill and granulate, ensuring uniform particle sizes without generating unwanted particles. The MultiMill is versatile across various applications, including the production of pharmaceutical tablets, nutraceutical supplements, chemical catalysts, and protein bars. Its cGMP model ensures compliance with rigorous industry standards like FDA and MHRA for pharmaceutical quality. Equipped with a user-friendly control panel featuring a potentiometer for speed adjustments, it operates quietly, minimizing downtime and enhancing operator safety. Constructed with stainless steel contact parts and offering a seamless design for tool-free maintenance, it promises durability and ease of cleaning, making it an integral component in continuous or batch processing lines.

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Processes Powders into Uniform Granules

The Oscilla Granulator from SSPM Systems & Engineers Pvt. Ltd. is designed to optimize granulation processes for pharmaceutical and nutraceutical manufacturers. This equipment features a trolley mount design and a variable frequency drive, allowing for precise control over particle size. The 360° rotation of the impeller, coupled with an adjustable gap between the sieve and impeller, ensures uniform granulation of powders, essential for consistent dosing in tablets, capsules, and protein powders. Capable of processing between 100 to 300 kg per hour, the Oscilla Granulator supports batch operations and integrates seamlessly into existing production lines. Fabricated with SS 316 contact parts for enhanced corrosion resistance and SS 304 non-contact parts, this granulator adheres to industry standards, ensuring reliability in both pharmaceutical and food production environments. Available sieve sizes range from 1 mm to 12 mm, offering versatility in processing different product types. This granulator is ideal for manufacturers needing efficient, consistent granulation to improve the quality of end products such as paracetamol tablets and whey protein powder.

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