Cleans, Disperses, and Degasses Laboratory Components

The Ultrasonic Bath Cleaner Series UR from Retsch is designed for rigorous laboratory use, providing precise cleaning for test sieves, grinding tools, metal, and glass components. These cleaners operate via a high-frequency generator that induces ultrasonic oscillations within the cleaning fluid, generating cavitation that effortlessly dislodges contaminants, ensuring your equipment remains accurate and reliable. Ideal for laboratories across pharmaceutical, chemical, and material testing industries, it offers batch processing with manual, bench-top operation. With three models—UR 1, UR 2, and UR 3—tailored for diverse sieve sizes and batch requirements, the series ensures efficient dispersal and degassing processes while maintaining low energy consumption. Constructed for longevity and minimal maintenance, it facilitates ease of integration into any laboratory setting, offering a compact, robust solution for maintaining clean and contaminant-free laboratory equipment.

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Processes and Refines Microspheres for Drug Delivery Systems

The MSR™ MicroSphere Refiner by Powder Systems Limited (PSL) is a comprehensive solution for pharmaceutical and biotechnology manufacturers focused on drug delivery via microspheres. This fully automated system integrates multiple stages of processing, including classification, filtration, de-watering, washing, drying, freeze-drying, sampling, and recovery. Designed for aseptic, batch operations, it addresses the challenge of handling valuable microspheric products by maximizing product recovery and maintaining batch consistency.

Featuring capabilities for both liquid and solid product types, the MSR™ accommodates various vessel sizes, with options supporting product cake volumes from 1.25 to 21.8 liters. The flexible design of the MSR™ supports multi-product applications, making it adaptable to rapidly changing production requirements. Enhanced process control is ensured through the integration of Process Analytical Technology (PAT), allowing for real-time quality monitoring and adherence to Good Manufacturing Practices (GMP), GAMP5, and 21 CFR Part 11 regulations.

The unit’s modular design supports seamless integration into existing pharmaceutical production lines, with vessel materials ensuring chemical compatibility and corrosion resistance. Maintenance is simplified via a Clean-In-Place (CIP) option, promoting contamination-free operations. The MSR™ is engineered for scalability, enabling a smooth transition from R&D to commercial production, ensuring critical process parameters are maintained throughout scale-up.

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Processes and Optimizes Liquid Formulations

The LSP-600 ultrasonic liquid processor from Kinematica AG is designed for feasibility testing and procedure optimization in R&D and laboratory settings. This processor utilizes a robust 600 W ultrasonic generator paired with an air-cooled transducer, facilitating efficient mixing and homogenization. It’s particularly suited for applications in biopharmaceuticals, fine chemicals, nutraceuticals, cosmetics, and food industries, aiding in the formulation of vaccines, APIs, protein supplements, and more. Capable of handling up to 2 L of liquid, the LSP-600 is equipped with a full-wave Barbell Horn® and a medium-duty support stand for stable operation. Optional features like a flow-through reactor chamber and peristaltic pump enhance versatility. While not automated in standard form, it integrates smoothly into pilot and bench-top operations, offering precision and consistency. Constructed with durable materials, this equipment ensures reliable performance across various operational conditions, supporting stringent compliance and industry standards.

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Cools and Transfers Heat in Sterile Solutions

The PUREX WFI Cooler Sanitary Heat Exchanger from Hydropure Systems Pvt Ltd ensures optimal temperature management for pharmaceutical and biopharmaceutical sterile solutions. This equipment offers precise heat exchange to maintain the stability of injectable vaccines, protein therapeutics, and other sensitive formulations. Designed for seamless integration into your production line, it supports multiple processes including filtration, softening, ultrafiltration, reverse osmosis, and purification. The automation options provide flexibility, with standard package systems available for varying batch sizes and continuous operations. Constructed from corrosion-resistant materials, it meets stringent industry guidelines, ensuring compliance with GMP standards. Enhance energy efficiency and operational reliability with Hydropure’s expert engineering and customized solutions tailored to your specific requirements.

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Slices Bakery and Food Products Precisely

The Compact Ultrasonic Slicer from Bakon Food Equipment offers precision slicing designed specifically for bakery and food industries, addressing the need for consistent slice quality in various production environments. Utilizing ultrasonic technology, it provides clean, accurate cuts across a range of shapes and sizes—perfect for products from brownies to soups. Supporting both low and high-capacity operations, this slicer integrates seamlessly into automated production lines and is ideal for both artisan bakeries and large-scale food manufacturers. Its PLC-controlled system allows for easy integration and remote monitoring. Built with energy efficiency in mind, it reduces power consumption by optimizing slicing speeds. The durable stainless-steel construction ensures excellent corrosion resistance, making it suitable for diverse processing environments. Customization options are available to tailor slicing parameters to specific production needs, and engineering support is provided for bespoke solutions. Designed for ease of maintenance, it includes a cleaning-in-place (CIP) system to facilitate quick and thorough cleaning, minimizing downtime.

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Sterilizes and Decontaminates Surfaces and Spaces

The POSS Hydrogen Peroxide Ultrafine Particle Sterilizer from AUSTAR offers an innovative solution for thorough sterilization needs across pharmaceuticals and biotechnology sectors. Utilizing over-frequency oscillation technology, it generates ultrafine particles under 5μm, enhancing Brownian motion and minimizing condensation. Ideal for applications involving injectables, sterile vaccines, and aseptic containment, this sterilizer ensures a 6 log microbial reduction on surfaces and in spaces. It operates efficiently with 6-8% hydrogen peroxide, offering both manual control and seamless integration into small-scale operations. Designed for materials sensitive to corrosion, it supports compliance with stringent pharmaceutical standards. Easy maintenance and reliable contamination control are hallmarks of this meticulously engineered equipment.

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Pre-washes and Ultrasonically Cleans Large Infusion Bottles

The Large Infusion Ultrasonic Pre-washing Machine from TRUKING Technology is engineered to enhance cleanliness in pharmaceutical manufacturing processes, specifically for large glass infusion bottles ranging from 30 to 500ml. Equipped with cutting-edge ultrasonic technology, this machine effectively removes difficult dust and particles from both the interior and exterior of bottles, ensuring high purity standards. It operates through a unique CNC integration approach, providing precise coupling and seamless integration with existing production lines.

Ideal for applications in biopharmaceuticals and pharmaceuticals, including vaccines, antibiotics, and IV fluids, it ensures bottles are thoroughly pre-washed before sterilization. With a processing capacity that adapts to continuous and high-speed operation, the machine offers flexibility with its mechanical-electrical integrative control, functioning both stand-alone and inline.

The machine incorporates an efficient water recycling system and dedicated nozzles to prevent cross-contamination, maintaining compliance with stringent cGMP and FDA regulations. Its ultrasonic cleaning, combined with star-wheel transmission, guarantees stable bottle handling during the process. Furthermore, customization options and comprehensive engineering support ensure the machine meets specific production demands, contributing to efficient line integration and reduced operational downtime.

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Extracts and Processes Hydrocarbon-Based Concentrates

The MEGA-miniMeP from ExtractionTek Solutions is a modular hydrocarbon extraction system engineered for cannabis and hemp concentrate producers. This closed-loop machine stands out with its ability to utilize propane, butane, or blended solvents, offering versatility across a range of extractions like shatter, wax, and live resin. With a material capacity of 20 liters, it processes up to 17.5 pounds per hour, making it ideal for high-throughput operations. The system’s design incorporates jacketed components to allow precise temperature control, crucial for optimizing extraction quality. The MEGA-miniMeP is PLC-controlled, facilitating seamless integration into existing workflows with minimal footprint, thanks to its compact 9-square-foot size. Constructed with U.S. Steel and high-quality components, it’s built to withstand rigorous use, while adhering to strict safety standards, including ASME and NFPA certifications, ensuring compliance across various operational jurisdictions.

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High-efficiency ultrasonic horn for liquid processing

The ultrasonic horn IUIP2500 designed by Cheersonic is an adaptable ultrasonic device for the industrial processing of liquid. The most representative process of ultrasound equipment is the extraction of natural active ingredients, which is widely used in traditional Chinese medicine preparation. Furthermore, ultrasonication is a proven technology for nanoparticles dispersion, a process broadly applied in emulsions preparation in industries such as health care, cosmetics, and food. The ultrasonic horn is a device with a transducer that transmits ultrasound energy to a liquid. When high-power ultrasound waves touch the liquid, cycles of high-and low-pressure are generated. In the low-pressure stage, small vapour bubbles are formed before they collapse. This phenomenon of bubble formation, growth and implosion is called acoustic cavitation. By breaking intermolecular bonds, the penetration of an active ingredient into a solvent is easier, and it allows for speeding up extraction time.

Employed for a lot of procedures such as emulsification, homogenization, extraction, dispersion, wet-milling and disintegration, ultrasonic barbells are mostly used for liquid treatment. Cheersonic has two types of ultrasonic horns, a prism, and a barbell, as a part of the laboratory, bench, and industrial-scale liquid treatment equipment. The ultrasonic horn can be customized according to customer needs in regard to the process. Power can range from 500watt up to 5000watt. Ultrasonic horns are made of titanium that is the most widely used alloy for its good acoustic transmission properties.

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Ultrasonic machine for extracting active ingredients in herbal medicine

The Prosonic1000 is a complete ultrasonic liquid treatment equipment that can be applied to the chemical and pharmaceutical (nanomaterial preparation), electronics (graphene preparation), food (sauces, mayonnaise, dietary supplements) and cosmetics (creams, ointments, lotions) industry. The machine designed by Cheersonic is a bridge between laboratory and small-scale production with the purpose to reduce the gap between experimental research and industrial production. The extraction process of natural products in the herbal medicine field is one of the most used applications for the Prosonic1000, but this ultrasonic equipment is also used for other procedures such as emulsification, homogenization, dispersion and lysis and cell disruption.

The operating principle of the Prosonic1000 is based on cavitation. During operation, a liquid is inserted into the tank through an open pump. The tank consists of two layers: internal and external layer. The internal layer stores the liquid, in which the ultrasonic horn transmits ultrasound waves. When high-power ultrasound waves touch the liquid, cycles of high-and low-pressure are generated. In the low-pressure stage, small vapour bubbles are formed before they collapse. This phenomenon of bubble formation, growth and implosion is called acoustic cavitation. By breaking intermolecular bonds, the penetration of an active ingredient into a solvent is easier, and it allows speeding up the extraction time. The ultrasonic horn can be customized according to customer needs in regard to the process. Moreover, the ultrasonic system has the ability to combine different operation modes, such as cyclic and static experimental methods.

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