Fills, Seals, and Stoppers Vials, Syringes, and Cartridges

The TRUKING Flextron Series Nest Fillers are designed to meet the diverse challenges faced by modern pharmaceutical manufacturers. This equipment facilitates the seamless filling, sealing, and stoppering of vials, pre-filled syringes, and cartridges. Utilizing a fully servo-controlled and robotic design, it ensures high throughput with minimal breakage, processing up to 36,000 units per hour. Its versatility enables handling multiple formats in a single unit, optimizing efficiency across various formulations including biologics and IV solutions.

Automation is enhanced with features like automatic de-bagging and vacuum stoppering, promising precise and bubble-free end products. The system offers in-house OEL 5 containment within custom C-RABS and Isolators for maximum safety and compliance with stringent GAMP, cGMP, and FDA standards. An industrial PC controls operations, ensuring comprehensive data integrity and remote access.

Construction incorporates superior SS 316L for product contact parts, enabling effective cleaning with built-in CIP & SIP systems. Customizable footprints and modular designs are available to fit specific cleanroom requirements, providing an ideal solution for biopharmaceutical applications, including insulin and vaccine production. The TRUKING Flextron Series does more than fill—it integrates performance with compliance, efficiency with precision.

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Preserves and Stabilizes Sensitive Pharmaceutical Products

Truking Technology’s Industrial Freeze Dryer is engineered for pharmaceutical and biotech industries, offering a robust solution for moisture removal in sensitive formulations. It operates on a sublimation principle, ensuring reliable preservation of vaccines, antibiotics, and nutraceuticals. With a high-capacity throughput, it streamlines production lines by optimizing energy use through variable-speed motor control, reducing consumption by up to 30%. The system is fully automated with PLC integration, allowing for seamless operation and remote diagnostics. Built with corrosion-resistant stainless steel, it complies with GMP and FDA standards, featuring built-in CIP systems for efficient, contamination-free cleaning. Comprehensive customization options are available, supported by Truking’s expert engineering team for tailored production needs.

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Sterilizes and Seals Pharmaceutical Products

The TRUKING Autoclave from TRUKING TECHNOLOGY LIMITED stands out for its precision in sterilizing pharmaceutical products. It features a real-time F0 value processing system, allowing for accurate sterilization against pressure and temperature parameters. This system is ideal for applications in biopharmaceuticals, such as vaccines and injectable formulations, ensuring a high standard of safety and compliance with GMP and FDA requirements.

Designed for continuous and high-speed operation, the TRUKING Autoclave can handle large-scale production, integrating seamlessly with upstream and downstream processes thanks to its industrial PC control with remote access and audit trail capabilities. The innovative jacketed chamber supports faster cooling cycles while maintaining energy efficiency.

Constructed with advanced TIG welding technology and a mirror-finished chamber at Ra 0.5um, the autoclave minimizes contamination risks. It includes a liquid ring pump for low-noise operation and a unique chamber door sealing device to maintain sealing pressure during power outages. Maintenance is simplified with an easy-access modular design and online sterilization and integrity testing features.

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Removes Pyrogens and Sterilizes Containers

The TRUKING Depyrogenization Tunnel is an essential solution for aseptic processing needs, leveraging advanced sterilization expertise to ensure optimal pyrogen removal. This cutting-edge tunnel utilizes state-of-the-art sterilization techniques, including a validated pressure differential system to maintain sterile conditions throughout the process. Designed to support biopharmaceutical and pharmaceutical tablet production, it ensures sterile manufacture of products like prefilled syringes, ampoules, and intravenous therapy bags.

Featuring a unique CNC-designed mesh belt and an auto wash-in-place system, it offers automatic cleaning and long-term operational reliability. With precise HEPA filter loading and negative pressure diversion technology, contaminant prevention is guaranteed. The tunnel supports automation and integration through IPC control, enabling audit trails and data integrity features compliant with 21 CFR Part 11.

Engineered for energy efficiency, the tunnel minimizes utility usage while maintaining strict compliance with GAMP, cGMP, and FDA regulations. It comes ready for customization with various material options, suited for diverse chemical processing environments, ensuring long-lasting performance and reducing maintenance downtime.

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Fills and Seals Ampoules for Pharmaceuticals

The Ampoule Filling and Sealing Machine from TRUKING TECHNOLOGY LIMITED offers pharmaceutical manufacturers and biotech companies a fully servo-driven solution for precise ampoule production. Utilizing state-of-the-art volumetric filling technology, it ensures dosing accuracy within ±0.5% to ±1%. This machine operates with an innovative walking beam design that minimizes vibration for superior sealing quality, even at high speeds. Applications include the production of insulin, vaccines, and antibiotic injectable liquids. With an industrial PC control system, it enables remote access and complies with 21 CFR Part 11, ensuring data integrity and audit trail capabilities. The compact ergonomic design supports seamless integration into existing production lines, while its customizable configuration caters to specific floor plan requirements. Additionally, it features an online CIP-SIP system for efficient cleaning and sterilization, making it suitable for aseptic processing environments. The equipment’s construction from SS316L and its progressive inert gas purging system further assure product quality by maintaining an oxygen residue of less than 1%.

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Ensures Aseptic Conditions and Personnel Safety

The Isolation System by TRUKING TECHNOLOGY LIMITED is engineered to provide exceptional aseptic conditions for sterile drug production. Utilizing a fully integrated hydrogen peroxide sterilization system, it ensures a sterility assurance level of SAL not greater than 10-6. This system is indispensable for the production of vaccines, injectable antibiotics, freeze-dried pharmaceuticals, and diagnostic reagents, aligning with stringent GMP and ISO standards. Constructed with SUS316L stainless steel, it features ergonomic design principles and comprehensive monitoring systems for temperature, humidity, and differential pressure. The ease of cleaning is facilitated by an optional WIP system for automatic chamber and pipeline maintenance. Customizable RTP valves and vertical rubber stopper cleaning machines can be configured to support specific industrial production needs. Compliant with 21CFR Part11 and certified by the EU CE, this isolation system offers pharmaceutical manufacturers, biopharmaceutical companies, and diagnostic reagent producers a robust solution for maintaining high standards of sterility and operational safety.

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Processes and Lyophilizes Pharmaceutical Products

The Industrial Freeze Dryer System from TRUKING integrates seamlessly into pharmaceutical production lines to enhance lyophilization processes for products such as vaccines, insulin, and diagnostic reagents. Utilizing a multi-stage freeze-drying method, the system efficiently removes moisture while preserving the structural integrity and potency of pharmaceuticals. With a high capacity, the system supports both pilot and large-scale operations, ensuring flexibility across batch and continuous processing modes. Engineered for energy efficiency, the system reduces consumption by 30% through optimized thermal management. It features PLC automation for precise control and remote monitoring, facilitating integration with existing information systems. Constructed from high-grade stainless steel, the dryer offers excellent corrosion resistance, compliant with GMP, cGMP, and FDA standards, making it ideal for sterile environments. An integrated Clean-In-Place (CIP) system guarantees swift and effective cleaning, minimizing downtime. Customization options available include chamber size adjustments and modular expansions to suit specific production requirements.

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Forms, Fills, and Seals Aseptic Containers

The TRUKING Blow Fill Seal Machine is a cutting-edge solution for aseptic packaging, ideal for pharmaceutical and biotech applications. It excels in forming, filling, and sealing containers with precision and reliability, ensuring product sterility and integrity. The machine utilizes an efficient extrusion and molding process, with a dosing system that consumes 30% less energy owing to optimized motor control. Capable of handling various container sizes from 0.5ml to 1 liter, it achieves a stable output of 24,000 units per hour for 2ml containers.

This machine is integral to processes where injectable and lyophilized products, ampoules, and pre-filled syringes are produced. It’s engineered to accommodate high-speed, continuous production environments with seamless integration into existing production lines through automated and PLC-controlled systems. Available in robust material options, it complies with stringent regulations such as GAMP, cGMP, and FDA standards. Maintenance is streamlined through a comprehensive CIP system, and custom molds and turnkey solutions are provided for specific client needs.

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Purifies Biopharmaceuticals and Diagnostic Reagents

Truking Technology’s AutoColumn AC series and EasyColumn series offer sophisticated solutions for biopharmaceutical and diagnostic reagent purification. The AutoColumn AC features a patented structural mechanics design, utilizing a double ball screw transmission for enhanced capacity and compactness, alongside a fluid simulation distributor ensuring high column efficiency. It supports automatic operations with a user-friendly wizard mode packing station and meets cGMP requirements, making it ideal for monoclonal antibody and freeze-dried vaccine production. The EasyColumn series provides a manual alternative with a unique lever-driven sealing system and 316L stainless steel construction for durability and corrosion resistance. Both series are equipped for optimal integration, ensuring streamlined processes for pharmaceutical and biotech industries.

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Purifies and Separates Biopharmaceutical Compounds

The AutoPrep and AutoSep series from TRUKING Technology are chromatography systems designed for the precise purification and separation of biopharmaceutical compounds. These systems excel with a sophisticated algorithm that enables fully automatic sample loading, collection, and monitoring. Ideal for applications involving insulin, monoclonal antibodies, vaccines, and more, this equipment supports both pilot and large-scale production. The AutoPrep series can process multiple samples concurrently with its multi-inlet system, and its modular installation simplifies maintenance. Equipped with a remote monitoring capability, it ensures efficient process control. Constructed to meet GMP regulations, it facilitates seamless integration into existing production lines and offers energy efficiency through optimized flow path management. Whether for R&D or manufacturing, these systems provide critical support in achieving consistent, high-purity products.

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