Enables Aseptic Sampling and Sterilization

The PE series of sampling devices from Equans – Pierre Guerin are engineered specifically for the rigorous demands of the food, beverage, and biopharmaceutical sectors. These devices are crafted from durable Stainless Steel EN 1.4404 (316 L) and are designed to be wall-mounted, ensuring seamless integration into your production line while maintaining aseptic conditions. Choose from four models—diaphragm, needle valve, manual sterilisable-in-place valve, or pneumatic sterilisable-in-place valve—to meet the specific needs of your operation. Ideal for sampling in applications requiring stringent quality and microbiological control, these devices support a variety of liquid end-products, including infant formula, vaccines, and energy drinks. Their robust construction ensures minimal maintenance while the clean-in-place and sterilisable-in-place features enhance operational efficiency. Suitable for environments upholding high standards of hygiene, these devices comply with industry certifications, delivering reliability and precision in your processing and sampling tasks.

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Extracts, Purifies, and Dispenses Lu-177 Radioisotopes

The Lu-177 N.C.A. Semiautomatic Production and Dispensing Plant, offered by Comecer, is a sophisticated system meticulously crafted to meet the demanding needs of radiopharmaceutical manufacturers and nuclear medicine facilities. This system is distinguished by its dual-chamber hot cell configuration—one chamber for extraction and purification, and the other for dispensing and terminal sterilization. It handles the complete workflow from separating Ytterbium-176 from Lutetium-177 to preparing terminally sterilized vials of Lu-177 radioisotope therapy doses.

Equipped with tele-manipulators, robotic dispensers, and semi-automatic dispensing technology, the system ensures precise micro-dose handling while maintaining safety with lead shielding and acid-proof fluoropolymer coatings. Its integration capability with customer-specific modules for automated extraction and purification enhances flexibility. The process automation is complemented by control systems for batch processing and remote handling, all while maintaining rigorous compliance with cGMP standards. Furthermore, the plant features a saturated steam autoclave and supports productivity of 50 vials in 8 hours, optimizing both efficiency and throughput in production. Customization options allow adaptation to specific operational needs, supported by comprehensive engineering support.

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Performs Aseptic Sampling and Sterilization

The VESTA® Sampling System from GEA is an advanced aseptic sampling solution designed for the stringent requirements of the pharmaceutical, biotech, cosmetics, and food industries. It operates through a modular system that facilitates sampling at various process points with precision and sterility. The use of PTFE bellows ensures a hermetic seal, crucial for preventing contamination in processes involving sterile injectable drugs, vaccines, and protein beverages.

Integrating seamlessly into both manual and automated setups, the VESTA® system supports adaptation to specific customer requirements. It utilizes a robust stainless steel framework that can be positioned horizontally or vertically, ensuring versatility in diverse production lines. The system’s optional expansions, including IZMAG™ flow meters and automated bottle monitoring, enhance its functionality while maintaining metrological accuracy through continuous calibration.

The system adheres to GMP and FDA standards, ensuring compliance for pharmaceutical applications, and supports easy cleaning with CIP/SIP optimization. Its modular build allows customization for unique production demands, supported by GEA’s engineering expertise, ensuring it meets all necessary regulatory and operational standards.

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Separates Microcarrier Beads in Cell Culture

The Harvestainer Microcarrier Separation System from Thermo Scientific is a reliable solution for efficient separation of microcarrier beads in adherent cell culture processes. This closed, single-use system enhances production by increasing yields and minimizing contamination risks through its in-line processing capabilities. Ideal for biopharmaceutical applications, including the production of vaccines and monoclonal antibodies, the system is scalable for both small and large-scale operations. It features a pre-assembled bioprocess container (BPC) with a dip tube designed for optimal drainage, reducing manual decanting and maintenance needs. With capacities ranging from 3L to 50L, it supports compliance with strict bioprocessing standards, offering sterilized PETG material suitable for diverse biopharma and biotech environments. By reducing clean-in-place and steam-in-place requirements, it significantly cuts down water for injection usage, thus aligning with sustainable production practices.

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Separates Microcarriers for Adherent Cell Cultures

The Harvestainer™ Microcarrier Separation System from Thermo Scientific is a cutting-edge solution for efficient separation of microcarrier beads in adherent cell culture processes. This closed, single-use system enhances product yield and reduces water and cleaning requirements. Designed for biotech and pharmaceutical applications, it supports the production of monoclonal antibodies, viral vectors, and engineered T cells. Available in capacities of 3 L, 12 L, 25 L, and 50 L, the system integrates seamlessly into existing production lines, offering scalability and high recovery rates. Its design minimizes manual intervention with a dip tube and dipwell for optimal drainage, while operating at room temperature. Constructed from durable PETG material, this system meets sterility standards and requires no additional maintenance, reducing cycle times and process validations. Suitable for various operations, it supports compliance with stringent industry regulations, providing reliability and precision in demanding environments.

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Purifies Biomolecules and Accelerates Chromatography Processes

Sartorius’ Sartobind® Rapid A, part of its esteemed chromatography portfolio, is specialized for swift and efficient biomolecule purification. This membrane system excel in high-throughput applications, leveraging rapid cycling to achieve up to 14x productivity increase during capture stages, beneficial for monoclonal antibodies and vaccine manufacturing. It eliminates the need for column packing, reducing operational time and freeing up your resources. Designed for column-free operation, it requires no additional setup, ensuring immediate deployment within your production line. Capable of integrating with existing systems, it supports batch and continuous operations, ideal for pharmaceutical and biotechnology environments. The Sartobind® Rapid A offers substantial cost savings by minimizing resin volumes used, contributing to reduced operational costs and increased process efficiency. Every unit is constructed to uphold compliance with GMP standards, facilitating seamless production while ensuring safety and reliability. With membrane chromatography’s inherent energy efficiency, anticipate a reduction in energy consumption throughout your bioprocessing activities.

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