Freeze Dries Vaccines and Liquid Formulations

The MINIFAST series from IMA Life represents a versatile solution for pharmaceutical and biotech R&D laboratories seeking precision in freeze drying. Bridging the gap between laboratory models and GMP production units, the MINIFAST employs patented FUSION™ shelf design to enhance drying efficiency and reliability. Available in MINIFAST 04 and MINIFAST 10 configurations, it supports shelf areas of 0.4 and 1.1 m², making it perfect for developmental and small-scale production of vaccines, monoclonal antibodies, and other sensitive liquid formulations. With a condensing capacity ranging from 8 to 20 kg and standard operating temperatures down to -85°C, it efficiently lyophilizes products while maintaining integrity. The rectangular chamber, made from corrosion-resistant AISI 304L stainless steel, ensures compatibility with stringent pharmaceutical standards. PLC-controlled operation and potential for integration into existing production systems add to its appeal for innovative R&D and pilot plant environments.

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Optimizes Freeze Drying for Biopharmaceuticals

The LYOFAST MINI from IMA Life is a compact pilot freeze dryer designed to bridge laboratory development and full-scale production. This equipment excels in optimizing freeze drying for critical applications such as vaccines, monoclonal antibodies, and lyophilized powders. It features four configurations, offering shelf areas from 1 to 2.8 m² with automatic stoppering pressure control. Integration is seamless with UAF, RABS, and isolators, supported by a compact SCADA system for comprehensive monitoring. The patented FUSION™ technology enhances heat transfer efficiency, allowing precise temperature control and energy usage reduction. Clean-in-place (CIP) and steam-in-place (SIP) systems ensure compliance with GMP standards, while flexible shelf spacing accommodates varied product types. Ideal for pharmaceutical, biotech, and food industries, the LYOFAST MINI supports R&D departments in scaling up freeze drying processes efficiently and reliably.

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Preserves Samples through Freeze-Drying and Lyophilization

The VirTis Genesis Pilot Freeze Dryer, from the esteemed Virtis brand, is engineered to deliver unmatched versatility for biopharmaceutical and research applications. It excels in freeze-drying by ensuring precise vacuum control and temperature uniformity, essential for producing lyophilized vaccines, monoclonal antibodies, and diagnostic assay kits. With over 100 flexible configurations, it accommodates both small-scale research and production needs, transitioning seamlessly from manual to automated operations. The Genesis Pilot features a full-color touchscreen and ethernet capabilities, enabling remote monitoring and integration into existing production lines. Constructed with 316L stainless steel, it offers superior chemical resistance, meeting stringent cGMP and 21 CFR Part 11 compliance requirements. Its customizable design supports cleanroom applications, while front-facing vacuum pump access minimizes downtime and streamlines maintenance processes.

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Precisely Freeze Dries and Vacuum Seals Samples

ZIRBUS technology’s VaCo Series offers a modular freeze dryer solution, adapted for precision in laboratory and pilot-scale applications. The series employs a robust freeze drying and lyophilization process, utilizing environmentally friendly natural refrigerants in compliance with EU F-Gas regulations. Available with condenser temperatures of either -50°C or -80°C, the VaCo 2, 5, and 10 models vary in condenser and ice capacities, tailoring to diverse operational needs. Ideal for biopharmaceuticals, nutraceuticals, and food products, the equipment integrates seamlessly into research and production lines, optimizing moisture removal from sensitive samples. Constructed with stainless steel, the series offers optional acrylic or stainless steel chambers for enhanced chemical compatibility, alongside customization options like heated shelves and vacuum controls, crucial for processing liquid and solid forms. Designed to meet the stringent requirements of the pharmaceutical, biotech, and food industries, the VaCo Series ensures consistent product quality, energy efficiency, and minimal environmental impact.

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Sterilizes and Conditions Liquid Pharmaceuticals

The SteriDelta W from Telstar is a superheated water shower sterilizer designed specifically for the sterilization of parenteral drugs and liquid pharmaceuticals in pharmaceutical and biopharmaceutical industries. This equipment leverages a high-flow recirculation system with a sanitary pump and heat exchanger to effectively sterilize, heat, and cool batches, ensuring containers emerge moist yet sterile. Ideal for processing liquid pharmaceuticals, the SteriDelta W showcases a compact and modular design, allowing seamless integration into existing production lines and ensuring compliance with European standards such as PED and CE marking. The design supports automatic operations and offers efficient sterilization cycles suitable for high-speed processing environments. Furthermore, its user-friendly features, including easy validation and maintenance, make it a versatile choice for demanding production conditions.

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Sterilizes Medical Devices and Hygroscopic Products

Ethylene oxide sterilization chambers from Telstar provide crucial sterilization solutions for the pharmaceutical and medical device industries. These turnkey chambers use ethylene oxide gas and vaporization for a thorough sterilization process, ensuring the safety of medical devices, intravenous solutions, and lyophilized vaccines. Featuring an automatic loading and unloading system, these chambers integrate seamlessly into production lines. Equipped with a SCADA system, they offer precise control over preconditioning, sterilization, and aeration phases. Their robust design supports compliance with strict GMP standards, and they include options for customizing chamber size and configurations to meet specific operational needs. The system’s connection to air purification systems ensures operator safety and environmental compliance, making it an essential component in maintaining sterile production environments.

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Unloads and Isolates Lyophilised Products

The Two Lyophiliser Unloading Isolators from Telstar offer specialized solutions for handling and unloading hygroscopic products post-freeze drying. These isolators are designed to provide low moisture control using dry N2 with precise dew point regulation. Ideal for pharmaceutical manufacturers and biotech companies, the equipment ensures safe manipulation of lyophilized vaccines, drugs, sterile injectables, and aseptic vials. With a structure comprising a left-hand chamber, middle pass chamber, and right-hand chamber, each with multiple glove ports, it facilitates seamless operation and prevents contamination. Fully compliant with GMP standards, these isolators support integration into existing aseptic and multi-chamber operations, offering engineering support for custom configurations.

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Ensures Safe Containment and Sterility

Telstar’s Containment Isolators are engineered to deliver unparalleled safety and sterility for pharmaceutical and biotech operations. Designed to protect operators and ensure product integrity, these isolators are ideal for handling hazardous materials and sterile injectable drugs. They integrate seamlessly with existing systems and support both stand-alone and continuous operations. Telstar offers customizable designs, including single and multi-chamber options, tailored to client needs. The isolators boast positive and negative pressure capabilities and are constructed from standardized mechanical and electrical components for reliability. With rigorous OEL containment validation to less than 200 picograms/m³ (OEB 8), they comply with GMP and ISO standards, ensuring suitability for cleanrooms of grade D and above. Built in the UK, these isolators feature energy-efficient solutions and ergonomic designs, and they include worldwide maintenance services to support long-term use.

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Provides Containment and Filters Air for Safety

The Telstar Downflow Booths are designed to meet stringent containment and air filtration requirements across diverse industries such as pharmaceuticals, chemicals, and robotics. Featuring ISO 5 air quality and negative pressure, these booths ensure triple protection for products, operators, and the environment. They are ideal for handling active pharmaceutical ingredients, chemical solvents, and optical components, offering modular customization to fit specific production needs.

Equipped with an efficient air handling system, Telstar Downflow Booths provide continuous contamination control, making them suitable for operations involving hazardous materials. Available in both standard and custom-built modular series, they can be integrated with additional equipment like scales and lifters, enhancing overall production line efficiency.

These booths are fully compliant with ISO 14644-1 and cGMP guidelines, ensuring stringent manufacturing standards are upheld. Designed with user-friendly features such as a complete 3D model and low maintenance requirements, they incorporate green technology options to optimize energy consumption. With ATEX explosion-proof versions, they cater to industries requiring robust safety measures against gas and dust hazards.

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Separates Operators from Critical Aseptic Environments

Telstar’s Restricted Access Barrier Systems (RABs) are designed to optimize aseptic processing by creating a high level of separation between operators and critical environments in pharmaceutical production. These systems are essential for manufacturing sterile injectable drugs, vaccines, and various biologics, offering a unique combination of physical barriers and dynamic airflow. RABs can be tailored to integrate with third-party equipment, ensuring compliance with GMP and current regulatory standards. They feature unidirectional laminar flow (active RABs) to maintain an ISO 5 positive pressure environment, crucial for protecting sensitive processes. With aseptic transfer capabilities for powders and liquids, and advanced environmental monitoring systems, these units are ideal for cleanrooms requiring enhanced sterility without the need for fully leak-tight isolators. Telstar supports customization and offers technical assistance, ensuring the RABs meet specific operational needs while facilitating ease of cleaning and maintenance through integrated systems.

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