Extracts, Purifies, and Dispenses Lu-177 Radioisotopes

The Lu-177 N.C.A. Semiautomatic Production and Dispensing Plant, offered by Comecer, is a sophisticated system meticulously crafted to meet the demanding needs of radiopharmaceutical manufacturers and nuclear medicine facilities. This system is distinguished by its dual-chamber hot cell configuration—one chamber for extraction and purification, and the other for dispensing and terminal sterilization. It handles the complete workflow from separating Ytterbium-176 from Lutetium-177 to preparing terminally sterilized vials of Lu-177 radioisotope therapy doses.

Equipped with tele-manipulators, robotic dispensers, and semi-automatic dispensing technology, the system ensures precise micro-dose handling while maintaining safety with lead shielding and acid-proof fluoropolymer coatings. Its integration capability with customer-specific modules for automated extraction and purification enhances flexibility. The process automation is complemented by control systems for batch processing and remote handling, all while maintaining rigorous compliance with cGMP standards. Furthermore, the plant features a saturated steam autoclave and supports productivity of 50 vials in 8 hours, optimizing both efficiency and throughput in production. Customization options allow adaptation to specific operational needs, supported by comprehensive engineering support.

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Sterilizes and Conditions Pharmaceutical Liquid Products

The Steristeam Air Steam Autoclave from Steriflow is engineered for precision in sterilizing pharmaceutical and biopharmaceutical products, such as vaccine vials, pre-filled syringes, and saline solution bags. Its unique cascade water system ensures uniform temperature distribution, reducing cycle time and energy usage. Equipped with a powerful fan for effective heat transfer, it incorporates MPI technology for real-time monitoring and control, facilitating seamless integration into high-speed, automated production lines. Pre-heating and cooling phases are efficiently managed with adjustable steam injection and water level control via a radar system. Made with durable materials like stainless steel to withstand corrosive environments, the autoclave meets GMP and FDA compliance standards, making it ideal for critical medical applications. Optional configurations and expert engineering support are available to meet specific operational needs. Cleaning is simplified with a built-in CIP system, ensuring minimal downtime and maintenance.

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Sterilizes and Decontaminates Pharmaceutical and Medical Equipment

The Saturated Steam Autoclave, including the Robustex 90L model, from Steriflow, is engineered specifically for pharmaceutical and medical device sterilization. This equipment stands out due to its ability to efficiently utilize pure steam sterilization, employing a vacuum system to ensure complete air removal and precise pressure control for effective decontamination. Designed from high-grade stainless steel (304L or 316L), it accommodates a range of diameters and capacities, from 200 liters upwards, suitable for sterilizing products such as vaccines, surgical tools, and animal bedding pellets. Its cycle begins with air evacuation using a liquid ring vacuum pump, followed by steam introduction for optimal sterilization. The system integrates internal exchangers for quick refrigeration and vacuum drying. Controllable via a user-friendly GAMP-compliant panel, it automatically saves parameters, guaranteeing traceability and ease of use. Service flexibility is enhanced with regular maintenance options, including inflatable door seals and specialized engineering support for qualification and validation. Complying with stringent industry standards like GMP and FDA, these autoclaves ensure reliable high-purity processing, making them indispensable for pharmaceutical manufacturers and healthcare facilities.

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Sterilizes and Cools Liquid Pharmaceutical Products

The Static Steriflow Autoclave from Steriflow is engineered for precise sterilization processes in the pharmaceutical and biotech industries. Specializing in sterilizing liquid formulations like vaccines, insulin injectables, and saline solutions, it guarantees homogeneity thanks to its advanced cascading water and air back-pressure management systems. This autoclave operates with automatic cycles, ensuring minimal supervision and consistent treatment of up to 7 baskets of products. Its powerful pump reduces cycle time, enhancing throughput while maintaining energy efficiency. Designed with stainless steel for durability, it minimizes the use of liquids through an efficient hydraulic circuit, suitable for temperatures under 105°C. The user-friendly MPI Expert control system supports compliance with 21CFR part 11, ensuring traceable and secure operation. Maintenance is straightforward due to its single moving part—the pump—making it both reliable and cost-effective for pharmaceutical manufacturers. Whether customizing for different packaging or ensuring stringent safety standards, Steriflow offers engineering support to meet your needs.

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Sterilizes and Rotates Canned Food and Beverages

The Rotary Steriflow from Steriflow is an engineered-to-order autoclave designed for the food and beverage industry, focusing on sterilization and mixing processes. This robust system features a stainless steel drum and triangulated structure, ensuring it withstands heavy packaging like cans, bottles, and jars without production downtime. The cascading water mechanism optimizes heat transfer, reducing processing time and energy costs. Suitable for canned beans, rice pouches, and bottled juices, it operates in batch mode, accommodating up to 12 baskets depending on size. Integrated with powerful pumps, the cycle uniformity ensures all products receive consistent treatment. The system is configurable for various product types, including solid and liquid, making it ideal for both processing and R&D departments. Constructed to meet rigorous industrial standards, it simplifies maintenance with high durability and reliability in diverse production environments.

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Sterilizes and Cools Packaged Foods and Beverages

The Static Steriflow Cascading Water Autoclave from Steriflow offers a robust and reliable solution for food, beverage, and pet food producers seeking efficient batch sterilization. Utilizing a cascading water system, it ensures uniform thermal treatment and cooling of products, leading to consistent and high-quality output. Its design incorporates a powerful pump that shortens sterilization cycles, thus improving energy efficiency and reducing operational costs. This autoclave can process various packaged forms, including jars, cans, and pouches, making it suitable for products such as baby food, meats, and sauces.

With a capacity ranging from 1 to 12 baskets, it accommodates different production scales, while the reduced number of mechanical parts simplifies maintenance and decreases downtime. The MPI programmer automates cycles and provides easy control, enhancing integration into existing production lines. The Steriflow Static is constructed with durable materials, ensuring longevity and compliance with industry standards. Its user-friendly interface lowers training needs, making it an excellent choice for facilities requiring high flexibility and efficiency with minimal maintenance.

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